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| 1 | Sacroiliac joint stability: Finite element analysis of implant number, orientation, and superior implant length显示文摘AIM To analyze how various implants placement variables affect sacroiliac(SI) joint range of motion. METHODS An experimentally validated finite element model of the lumbar spine and pelvis was used to simulate a fusion of the SI joint using various placement configurations of triangular implants(iF use Implant System~?). Placement configurations were varied by changing implant orientation, superior implant length, and number of implants. The range of motion of the SI joint was calculated using a constant moment of 10 N-m with a follower load of 400 N. The changes in motion were compared between the treatment groups to assess how the different variables affected the overall motion of the SI joint. RESULTS Transarticular placement of 3 implants with superior implants that end in the middle of the sacrum resulted in the greatest reduction in range of motion(flexion/extension = 73%, lateral bending = 42%, axial rotation = 72%). The range of motions of the SI joints were reduced with use of transarticular orientation(9%-18%) when compared with an inline orientation. The use of a superior implant that ended mid-sacrum resulted in median reductions of(8%-14%) when compared with a superior implant that ended in the middle of the ala. Reducing the number of implants, resulted in increased SI joint range of motions for the 1 and 2 implant models of 29%-133% and 2%-39%, respectively,when compared with the 3 implant model.CONCLUSION Using a validated finite element model we demonstrated that placement of 3 implants across the SI joint using a transarticular orientation with superior implant reaching the sacral midline resulted in the most stable construct. Additional clinical studies may be required to confirm these results. | Derek P Lindsey Ali Kiapour Scott A Yerby Vijay K Goel | 2018 | World Journal of Orthopedics2018，9，3： | 3 |
| 2 | Multidisciplinary approach for multifocal, bilobar hepatocellular carcinoma: A case report and literature review显示文摘BACKGROUND Hepatocellular carcinoma(HCC) is the second most lethal malignancy worldwide. There has been virtually no change in the survivability of HCC in spite of improvement in therapies. Surgery is considered the ideal first, curative intervention, however most patients present in advanced stages with unresectable disease. Therefore, systemic and liver-directed non-operative therapies are initially offered to downstage the disease. To ensure optimal management, a multidisciplinary team approach is often warranted. Our case highlights the benefits of a multidisciplinary approach in a young woman with multifocal, bilobar HCC.CASE SUMMARY A 36-year-old Chinese woman with untreated hepatitis B was found to have large bilobar HCC during work up for abdominal pain. Her initial serum alphafetoprotein was significantly elevated to 311136 ng/mL. Computed tomography scan demonstrated bulky bilobar liver masses, consistent with intermediate stage HCC, Barcelona Clinic Liver Cancer Stage B. Her case was discussed and a personalized care plan was developed at the Multidisciplinary Center for Advanced Minimally Invasive Liver Oncologic Therapies at the University of Washington. She initially underwent bilobar transarterial chemoembolization with partial response of the left lobar tumor. Salvage hypofractionated proton beam radiation therapy was delivered to the right lobe followed by two additional transarterial chemoembolizations to the left lobe with good response.Finally, to remove left lobar residual disease, she was taken to the operating roomfor a left hepatectomy eleven months after her initial presentation. She continues to be without evidence of disease.CONCLUSION Coordinating the multiple HCC treatment modalities is complex and our case highlights the benefits of a multidisciplinary approach. | Kevin P Labadie Stephanie K Schaub Derek Khorsand Guy Johnson Smith Apisarnthanarax James O Park | 2019 | World Journal of Hepatology2019，11，1： | 2 |
| 3 | A novel flow battery-A lead acid battery显示文摘 | AHMED H DEREK P RICHARD W | 2004 | Phys Chem Chem Phys2004，，6： | 1 |
| 4 | B-type natriuretic peptide limits infarct size in rate isolated hearts via KATP channel opening显示文摘 | Savio P Souza D Derek M | 2003 | Sm J Physiol Heart Circ Physiol2003，284，6： | 1 |
| 5 | Location of sources of evoked scalp potentials: corrections for skull and scalp thicknesses显示文摘 | James P A Stanley A K Derek H F | 1981 | IEEE Transaction Biomedical Engineering1981，28，6： | 1 |
| 6 | Role of prior exposure on anaerobic degradation of naphthalene and phenanthrene in marine harbor sediments显示文摘 | Lnry A Hayes Kelly P Nevin Derek R Lovley | 1999 | Organic Geochemistry1999，30，： | 1 |
| 7 | Engineered and Designed Peptide-based Fibrous Biomaterials显示文摘 | CAIT E M DEREK P WPPLFSON N | 2004 | Current Opinion in Solid State and Materials and Science2004，，8： | 1 |
| 8 | The Use of an Interspinous Implant in Conjunction With a Graded Facetectomy Procedure 显示文摘 | Fuchs P D Derek PL Ken YH | 2005 | SPINE2005，30，11： | 1 |
| 9 | B-type natriuretic peptide limits infarct size in rate isolated hearts via KATPchannel opening显示文摘 | Savio P D'Souza Derek M | 2003 | Sm J Physiol Heart Circ Physiol2003，284，： | 1 |
| 10 | Approximate conditional mean particle filtering for linear/nonlinear dynamic state space models显示文摘 | Derek Yee Reilly Kirubarajan J P Punithakumar T K | 2008 | Signal Processing2008，56，12： | 1 |
| 11 | Development of progres- sive landslide failure in cohesive materials显示文摘 | David N P Toru H Derek J P | 2005 | Geology2005，33，3： | 1 |
| 12 | Cooperative control for oceansampling: the glider coordinated control system 显示文摘 | Derek P Zhang F M Leonard N E | 2008 | IEEE Trans-actions on Control Systems Technology2008，16，4： | 1 |
| 13 | Electrobiocommodities: powering microbial production of fuels and commodity chemicals from carbon dioxide with electricity显示文摘 | Derek R Lovley Kelly P Nevin | 2013 | Current Opinion in Biotechnology2013，，3： | 1 |
| 14 | Vitamin C and quinapril abrogate LVH and endothelial dysfunction in aortic-banded guinea pigs显示文摘 | John P Salah I Derek L Donaldson F Lewis M | 2001 | Am J Physiol Heart Circ Physiol2001，281，： | 1 |
| 15 | Cooperative control for ocean sampling: the glider coordinated control system显示文摘 | DEREK P ZHANG F M LEONARD N E | 2008 | IEEE Transactions on Control Systems Technol- ogy2008，16，4： | 1 |
| 16 | Influence of iron on the synthesis and stability of yttrium silicate apatite显示文摘 | JULIEN PARMENTIER KATH LIDDELL DEREK P THOMPSON | 2001 | Solid State Sciences2001，3，： | 1 |
| 17 | Solvent-resistant photocurable“liquid teflon”for microfluidic device fabrication显示文摘 | Jason P Rolland R Michael Van Dam Derek A Schorzman | 2004 | Journal of the American Chemical Society2004，126，8： | 1 |
| 18 | In situ light scattering measurements of mainstream and sidestream cigarette smoke显示文摘 | CHUNG I P DEREK D R | 1996 | Aerosol Science and Technology1996，24，2： | 1 |
| 19 | Understanding the origin, activation and regulation of matrix‐producing myofibroblasts for treatment of fibrotic disease显示文摘 | Rafael Kramann Derek P DiRocco Benjamin D Humphreys | 2013 | J Pathol2013，，3： | 1 |
| 20 | Organic matter mineralization with reduction of ferric iron in Anaerobic sediments 显示文摘 | Derek R Lovley Elizabeth J P Phillips | 1986 | Applied and Environmental Microbiology1986，51，4： | 1 |
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