|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A human herpesvirus miRNA attenuates interferon signaling and contributes to maintenance of viral latency by targeting IKKε显示文摘类型我发信号的干扰素(IFN ) 是调停的主要反应抗病毒的天生的免疫。IFN 抄写依赖于抄写因素 IRF3/IRF7 和 NF-B 的激活。许多病毒的蛋白质作为能够防碍 IFN 发信号从主人便于避免被显示出天生的有免疫力的反应。这里,我们报导那病毒的 miRNA, miR-K12-11,由 Kaposi 的联系肉瘤的 herpesvirus (KSHV ) 编码了为 IFN 通过指向 I-kappa-B kinase epsilon (IKK ) 发信号和行为的调整是批评的。miR-K12-11 的宫外的表示导致了减少的 IKK 表示,当 miR-K12-11 的抑制被发现在感染 KSHV 的房间恢复 IKK 表示时。重要地, miR-K12-11 的表示稀释了由减少的调停 IKK 的 IRF3/IRF7 phosphorylation 并且由禁止刺激基因(ISG ) 的 IKK 依赖的 IFN 的激活发信号的 IFN,允许抗病毒的免疫的 miR-K12-11 抑制。我们的数据建议由 miR-K12-11 指向的 IKK 是 KSHV 利用调制在 KSHV 生命周期期间发信号的 IFN 的重要策略,特别在潜伏。我们也证明 IKK 能与 12-O-tetradecanoylphorbol 13 醋酸盐的处理 synergistically 提高 KSHV 复活。而且, miR-K12-11 的抑制提高了小囊的口炎病毒感染导致的 KSHV 复活。一起拿,我们的调查结果也建议 miR-K12-11 能由指向 IKK 贡献 KSHV 潜伏的维护。 | Deguang Liang Yuan Gao Xianzhi Lin Zhiheng He Qinglan Zhao Qiang Deng Ke Lan | 2011 | Cell Research2011，21，5： | 15 |
| 2 | Operator valued frames and structured quantum channels显示文摘Operator-valued frames are natural generalization of frames that have been used in many applied areas such as quantum computing, packets encoding and sensor networks. We focus on developing the theory about operator-valued frame generators for projective unitary representations of finite or countable groups which can be viewed as the theory of quantum channels with group structures. We present new results for operator-valued frames concerning (general and structured) dilation property, orthogonal frames, frame representation and dual frames. Our results are complementary to some of the recent work of Kaftal, Larson and Zhang, and in some cases our treatment is more elementary and transparent. | HAN DeGuang LI PengTong MENG Bin TANG WaiShing | 2011 | Science China Mathematics2011，54，11： | 8 |
| 3 | Effects of casein glycomacropeptide supplementation on growth performance,intestinal morphology, intestinal barrier permeability and inflammatory responses in Escherichia coli K88 challenged piglets显示文摘Casein glycomacropeptide(CGMP) is a bioactive peptide derived from milk with multiple functions. This study was aimed at evaluating the effects of CGMP as a potential feed additive on growth performance,intestinal morphology, intestinal barrier permeability and inflammatory responses of Escherichia coli K88(E. coli K88) challenged piglets. Eighteen weaning piglets were randomly assigned to three groups.Control group and K88 challenged group received a basal diet, and CGMP treated group received the basal diet supplemented with 1% of CGMP powder. The trail lasted for 12 days, K88 was orally administered to the piglets of K88 challenged group and CGMP treated group on days 8-10. The results showed that the diet containing 1% CGMP significantly alleviated the decrease in average daily gain(P <0.05),increase in pathogenic bacteria amounts in intestinal contents(P < 0.05), intestinal morphology(P > 0.05) and barrier permeability damage(P < 0.05), and acute inflammatory response(P < 0.05)induced by E. coli K88 infection. In conclusion, CGMP supplementation in the diet protected the weaning piglets against E. coli K88 infection. | Yili Rong Zeqing Lu Haiwen Zhang Lin Zhang Deguang Song Yizhen Wang | 2015 | Animal Nutrition2015，，2： | 7 |
| 4 | Precipitation Behavior of TiN in Bearing Steel显示文摘The precipitation behavior of titanium nitride (TiN) in bearing steel and effects of TiN inclusions on quality of the steel have been studied by thermodynamic calculation and experiment. The results show that with the increase of the content of Ti and [N], the properties of bearing steel decreased; adjusting the content of N and Ti could influence the precipitation occasion and condition of TiN in the steels. If Ti content is less than 30 x 10-6 and nitrogen content is less than 53x 10-6, the temperature of TiN precipitation is under the solidus temperature and the size is small so that they have little harmful and even beneficial effect on the properties owing to grain refinement. | Deguang ZHOU, Jie Ftf, Xichun CHEN and Jing LIInstitute of Electric Metallurgy, University of Science and Technology Beijing, Beijing 100083, China | 2003 | Journal of Materials Science & Technology2003，19，2： | 6 |
| 5 | Eco-spatial Structure of Urban Agglomeration显示文摘In terms of ecological theory, this paper makes a comprehensive analysis of the mutualism and co- evolutionary mechanism between the eco-spatial structure and socio-economic development of the urban agglomeration, and maps out optimized modes of the eco-spatial structure of the urban agglomeration. The analysis is a case study of the urban agglomeration on different levels of global, national, provincial and local scales, on the basis of those conclusions are drawn: 1) Within the scope of the urban agglomeration, the cities should be reasonably sized and appropriately densified; the spatial combination of the urban agglomeration ought to be orderly, and its eco-spatial structure ought to be optimized and efficient; the relationship between the economic society and eco-spatial environment ought to be that of mutual benefit and co-evolution. 2) “The mode of corridor group network” is a certain trend evoked from the spatial structure of urban agglomeration. 3) The eco-spatial structure of urban agglomeration under “the mode of corridor group network” can further increase the environmental capacity of urban agglomeration, and is in favor of the harmonious relationship between man and nature. | GUO Rongchao MIAO Changhong LI Xuexin CHEN Deguang | 2007 | Chinese Geographical Science2007，17，1： | 5 |
| 6 | Discussions on real-world acupuncture treatments for chroni clow-back pain in older adults显示文摘Chronic low-back pain(CLBP) is one of the most common pain conditions. Current clinical guidelines for low-back pain recommend acupuncture for CLBP. However, there are very few high-quality acupuncture studies on CLBP in older adults. Clinical acupuncture experts in the American Traditional Chinese Medicine Association(ATCMA) were interested in the recent grant on CLBP research announced by the National Center for Complementary and Integrative Health. The ATCMA experts held an online discussion on the subject of real-world acupuncture treatments for CLBP in older adults. Seven participants, each with more than 20 years of acupuncture practice, discussed their own unique clinical experience while another participant talked about the potential mechanism of acupuncture in pain management. As a result of the discussion, a picture of a similar treatment strategy emerged across the participants for CLBP in older adults. This discussion shows that acupuncture may have complicated mechanisms in pain management, yet it is effective for the treatment of chronic pain involving maladaptive neuroplasticity;therefore, it should be effective for CLBP in older adults. | Arthur Yin Fan Hui Ouyang Xinru Qian Hui Wei David Dehui Wang Deguang He Haihe Tian Changzhen Gong Amy Matecki Sarah Faggert Alemi | 2019 | Journal of Integrative Medicine2019，17，2： | 5 |
| 7 | A CIB1-LIKE transcription factor GmC IL10 from soybean positively regulates plant flowering显示文摘CRYPTOCHROME-INTERACTING basic helix-loop-helix 1(CIB1) is a well characterized transcriptional factor which promotes flowering through the physical interaction with the blue light receptor CRYPTOCHROME 2(CRY2) in Arabidopsis. However, the role of its counterpart in crop species remains largely unknown. Here, we describe the isolation and characterization of a CIB1 homolog gene, Glycine max CIB1-LIKE10(GmC IL10), from soybean genome. The m RNA expression of GmC IL10 in the unifoliate leaves shows a diunal rhythm in both long day(LD) and short day(SD) photoperiod, but it only oscillates with a circadian rhythm when the soybean is grown under LDs, indicating that the clock regulation of GmC IL10 transcription is LD photoperiod-dependent. Moreover, its m RNA expression varies in different tissue or organs, influenced by the develpomental stage, implying that GmC IL10 may be involved in the regulation of multiple developmental processes. Similar to CIB1, Gm CIL10 was evident to be a nuclei protein and ectopically expression of GmC IL10 in transgenic Arabidopsis accelerates flowering under both LDs and SDs, implying that CIBs dependent regulation of flowering time is an evolutionarily conserved mechanism in different plant species. | YANG DeGuang ZHAO Wang MENG YingYing LI HongYu LIU Bin | 2015 | Science China(Life Sciences)2015，58，3： | 4 |
| 8 | Carbon Segregation of Bearing Steel Concasting Billet显示文摘The formation mechanism of 'white band' and central carbon segregation of high-carbon Cr bearing steel concasting billets are discussed in this paper. The maximum oxygen content in the steel produced by concasting process was 13 ?10-6 with an average oxygen content of 9.3?10-6. Comparison of metallurgical quality and fatigue property between the concasting steel (CC) and ingot casting steel (IC) showed that the carbon segregation (C/C0) in former steel was 0.921.10 and its fatigue life was equal to that of the latter steel. | Deguang ZHOU, Jie FU and Ping WANG (University of Science and Technology Beijing, Beijing 100083, China) Junhao XU, Yaqing XIE and Zheng LI (Daye Special Steel Co. Ltd, Huangshi 435001, China) | 2000 | Journal of Materials Science & Technology2000，16，3： | 4 |
| 9 | Synthesis and Microstructure Analysis of Autoclaved Aerated Concrete with Carbide Slag Addition显示文摘Synthesis of autoclaved aerated concrete(AAC) has been carried out with carbide slag addition, and the carbide slag could be used as a main material to produce the AAC with the compressive strength about 2 MPa and the density below 0.6 g?cm-3. In this study, quartz sand acted as frame structure phase in the matrix, and quartz addition also infl uenced the Si/Ca of starting material. Tobermorite and CSH gel were formed readily at 62%, which seemed to enhance the compressive strength of samples. Curing time seemed to affect the morphology of phase produced, and specimen with the plate-like tobermorite formed at 10 h appeared to have a better compressive strength development than the fiber-like one at 18 h. The higher curing temperature seemed to favor the tobermorite and CSH gel formation, which also exerted a significant effect on the strength development of the samples. On the micro-scale, the formed CSH gel was filled in the interface of the matrix, and the tobermorite appeared to grow in internal-surface of the pores and interstices. The tobermorite or/and CSH formation seemed to densify the matrix, and therefore enhanced the strength of the samples. | 范俊杰 CAO Deguang 景镇子 ZHANG Yi PU Li JING Yani | 2014 | Journal of Wuhan University of Technology(Materials Science)2014，29，5： | 4 |
| 10 | A UNIFIED MULTIAXIAL FATIGUE DAMAGE PARAMETER显示文摘According to the critical plane principle,a unified multiaxial fatigue damage parameteris presented based on the varying behaviour of the strains on the critical plane.Both the parameters ofthe maximum shear strain amplitude and normal strain excursion between adjacent turning points ofthe maximum shear strain on the critical plane are considered in the multiaxiaI fatigue damage parame-ter presented.An equivalent strain amplitude is made with both parameters of the maximun shearstrain amplitude and normal strain excursion by means of yon Mises criterion.Thus a new multiaxialfatigue damage model is given based on the critical plane approach.The results show that the multiaxi-al fatigue damage parameter proposed in this paper may be used under either proportional or nonpro-portional loading,and may also be reduced to a uniaxial form.It is used to predict multiaxial fatiguelife and good agreement is demonstrated by experimental data. | Shang Deguang Wang Dejun Xu Hao | 1998 | Acta Mechanica Solida Sinica1998，11，3： | 4 |
| 11 | A new checkpoint against ferroptosis显示文摘By taking different approaches,two research groups made the same discovery that a CoQ oxidoreductase(renamed as ferroptosis suppressor protein-1,or FSP1)can inhibit ferroptosis,a form of cell death driven by iron-dependent phospholipid peroxidation.As FSP1 is expressed in various cancers and can halt ferroptosis even in the absence of glutathione peroxidase 4(GPX4),which was previously considered indispensable for ferroptosis surveillance,the potential of FSP1 as a new cancer therapeutic target should be explored. | Deguang Liang Liang Deng Xuejun Jiang | 2020 | Cell Research2020，30，1： | 4 |
| 12 | The Shanghai Cooperation Organization: Heading Toward New Glory显示文摘 | Zhang Deguang is Secretary General of the Shanghai Cooperation Organization. | 2006 | China International Studies2006，26，2： | 3 |
| 13 | Derivations and Isomorphisms of Certain Reflexive Operator Algebras | Hou Chengjun Han Deguang Department of Mathematics, Qufu Normal University, Qufu 273165, China Institute of Mathematics, Fudan University, Shanghai 200433, China Department of Mathematics, Qufu Normal University, Qufu 273165, China | 1998 | Acta Mathematica Sinica,English Series1998，14，1： | 3 |
| 14 | Constructing super Gabor frames:the rational time-frequency lattice case显示文摘For a time-frequency lattice Λ = A Z d × B Z d , it is known that an orthonormal super Gabor frame of length L exists with respect to this lattice if and only if |det( AB) | = 1 L . The proof of this result involves various techniques from multi-lattice tiling and operator algebra theory, and it is far from constructive. In this paper we present a very general scheme for constructing super Gabor frames for the rational lattice case. Our method is based on partitioning an arbitrary fundamental domain of the lattice in the frequency domain such that each subset in the partition tiles R d by the lattice in the time domain. This approach not only provides us a simple algorithm of constructing various kinds of orthonormal super Gabor frames with flexible length and multiplicity, but also allows us to construct super Gabor (non-Riesz) frames with high order smoothness and regularity. Several examples are also presented. | LI ZhongYan 1 & HAN DeGuang 2, 1 Department of Mathematics and Physics, North China Electric Power University, Beijing 102206, China 2 Department of Mathematics, University of Central Florida, Orlando, FL 32816, USA | 2010 | Science China Mathematics2010，53，12： | 3 |
| 15 | CONTINUITY AND LINEARITY OF ADDITIVE DERIVATIONS OF NEST ALGEBRAS ON BANACH SPACES显示文摘This paper discusses the problem concerning the continuity and linearity of additive derivation of nest algebras on normed spaces. It is proved that erevy linear derivation of a nest algebra algN is continuous provided that one of the following conditions is satisfied:(1)0+(包含)0.(2)X-(包含于)X.(3)there exists a non-trivial idempotnet p in algN such that the range of p belongs to N, It is also proved that every additive derivation of a nest algebra is automatically linear if the underlying normed space is infinite dimemnsional. | HAN DEGUANG Department of Mathematics, Qufa Normal University, Qufu 273165, Shandong, China. | 1996 | Chinese Annals of Mathematics,Series B1996，17，2： | 3 |
| 16 | Carbon isotopic compositions of individual terpenoids in heavy oils from Karamay oilfield显示文摘The carbon isotopic compositions of individual terpenoids in the heavy oils from the Karamay oilfield were determined by using the method of enrichment of terpanes with molecular sieve 13X and GC-IRMS technique. The terpanes, selectively enriched from the biodegraded oils with molecular sieve 13X, can meet the demand of GO-IRMS analysis. The carbon isotopic compositions of the hopanoids (δ13C-31.7‰—-37.8‰) infer that their main source is probably non-methanotrophic bacteria,and that the depositional environment of source rocks is a strongly reductive, rapidly depositional, and closed-semi-closed saline lagoon. | Yongqiang Xiong Ansong Geng Deguang Liu | 1999 | Chinese Science Bulletin1999，44，3： | 2 |
| 17 | Rapid detection of orf virus by loop-mediated isothermal amplification based on the DNA polymerase gene显示文摘 | Jida Li Deguang Song Wenqi He Yingfu Bao Rongguang Lu Gaoli Su Gaili Wang Huijun Lu Kui Zhao Feng Gao | 2013 | Archives of Virology2013，，4： | 2 |
| 18 | Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry显示文摘 | CHEN Rui JIANG Xinning SUN Deguang | 2009 | Journal of Proteome Research2009，8，2： | 1 |
| 19 | Efficacy and safety of bronchoscopic cryotherapy for granular endobronchial tuberculosis 显示文摘 | Deguang Mu Dongyan Nan Wangping Li | 2011 | Respiration2011，82，3： | 1 |
| 20 | Metformin reverses multidrug resistance in human hepatocellular carcinomaBel?7402/5?fluorouracil cells显示文摘 | Sunbin Ling Yu Tian Haiquan Zhang Kaiqi Jia Tingting Feng Deguang Sun Zhenming Gao Fei Xu Zhaoyuan Hou Yan Li Liming Wang | 2014 | Molecular Medicine Reports2014，，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员