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| 1 | Lesion-symptom mapping with NIHSS sub-scores in ischemic stroke patients显示文摘Background Lesion-symptom mapping(LSM)is a statistical technique to investigate the population-specific relationship between structural integrity and post-stroke clinical outcome.In clinical practice,patients are commonly evaluated using the National Institutes of Health Stroke Scale(NIHSS),an 11-domain clinical score to quantitate neurological deficits due to stroke.So far,LSM studies have mostly used the total NIHSS score for analysis,which might not uncover subtle structure–function relationships associated with the specific sub-domains of the NIHSS evaluation.Thus,the aim of this work was to investigate the feasibility to perform LSM analyses with sub-score information to reveal category-specific structure–function relationships that a total score may not reveal.Methods Employing a multivariate technique,LSM analyses were conducted using a sample of 180 patients with NIHSS assessment at 48-hour post-stroke from the ESCAPE trial.The NIHSS domains were grouped into six categories using two schemes.LSM was conducted for each category of the two groupings and the total NIHSS score.Results Sub-score LSMs not only identify most of the brain regions that are identified as critical by the total NIHSS score but also reveal additional brain regions critical to each function category of the NIHSS assessment without requiring extensive,specialised assessments.Conclusion These findings show that widely available sub-scores of clinical outcome assessments can be used to investigate more specific structure–function relationships,which may improve predictive modelling of stroke outcomes in the context of modern clinical stroke assessments and neuroimaging. | Deepthi Rajashekar Matthias Wilms M Ethan MacDonald Serena Schimert Michael D Hill Andrew Demchuk Mayank Goyal Sean P Dukelow Nils Daniel Forkert | 2022 | Stroke & Vascular Neurology2022，7，2： | 7 |
| 2 | Antioxidant activity of some substituted 1,2,4-triazo-5-thione schiff base显示文摘 | Valentina P Ilango K Deepthi M | 2009 | J Pharm Sci and Res2009，1，2： | 1 |
| 3 | Design implementation and analysisof hardware efficient stream ciphers using LFSR based hashfunctions显示文摘 | Deepthi P P Sathidevi P S | 2009 | Computers & Security2009，28，34： | 1 |
| 4 | Design implementation and analysis of hardware efficient stream ciphers using LFSR based hash functions显示文摘 | Deepthi P P Sathidevi P S | 2009 | Computers & Security2009，28，34： | 1 |
| 5 | An Adaptive Technique for the Extraction of Object Region and Boundary from Images with Complex Environment显示文摘 | Deepthi P Valaparla Vijayan K Asari | | IEEE0，，： | 1 |
| 6 | TGFB1 functional gene polymorphisms(C-509T and T869C) in the maternal susceptibility to pre-eclampsia in South Indian women显示文摘 | Deepthi G Chaithri PK Latha P | 2015 | Scand J Immunol2015，82，4： | 1 |
| 7 | Purification and Characterization of Bacteriocin Produced by Lactobaeillus plantarum Isolated from Cow Milk显示文摘 | N Ravi SankarV Deepthi Priyanka P Srinivas Reddy | 2012 | International Journal of Microbiological Research2012，，2： | 1 |
| 8 | TGFB1 Functional Gene Polymorphisms(C-509T and T869C)in the Maternal Susceptibility to Pre-eclampsia in South Indian Women显示文摘 | Deepthi G Chaithri PK Latha P | 2015 | Scand J Immunol2015，，4： | 1 |
| 9 | Effect of porogen on the catalytic activity of molecular imprinted polymers 显示文摘 | DEEPTHI K P MATHEW B | 2013 | Asian J Chem2013，，： | 1 |
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