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| 1 | Lesion-symptom mapping with NIHSS sub-scores in ischemic stroke patients显示文摘Background Lesion-symptom mapping(LSM)is a statistical technique to investigate the population-specific relationship between structural integrity and post-stroke clinical outcome.In clinical practice,patients are commonly evaluated using the National Institutes of Health Stroke Scale(NIHSS),an 11-domain clinical score to quantitate neurological deficits due to stroke.So far,LSM studies have mostly used the total NIHSS score for analysis,which might not uncover subtle structure–function relationships associated with the specific sub-domains of the NIHSS evaluation.Thus,the aim of this work was to investigate the feasibility to perform LSM analyses with sub-score information to reveal category-specific structure–function relationships that a total score may not reveal.Methods Employing a multivariate technique,LSM analyses were conducted using a sample of 180 patients with NIHSS assessment at 48-hour post-stroke from the ESCAPE trial.The NIHSS domains were grouped into six categories using two schemes.LSM was conducted for each category of the two groupings and the total NIHSS score.Results Sub-score LSMs not only identify most of the brain regions that are identified as critical by the total NIHSS score but also reveal additional brain regions critical to each function category of the NIHSS assessment without requiring extensive,specialised assessments.Conclusion These findings show that widely available sub-scores of clinical outcome assessments can be used to investigate more specific structure–function relationships,which may improve predictive modelling of stroke outcomes in the context of modern clinical stroke assessments and neuroimaging. | Deepthi Rajashekar Matthias Wilms M Ethan MacDonald Serena Schimert Michael D Hill Andrew Demchuk Mayank Goyal Sean P Dukelow Nils Daniel Forkert | 2022 | Stroke & Vascular Neurology2022,7,2: | 7 |
| 2 | AIDS-associated plasmablastic lymphoma presenting as a poorly differentiated esophageal tumor: A diagnostic dilemma显示文摘Plasmablastic lymphoma (PBL) is a rare form of diffuse large B-cell lymphoma characterized by weak/absent expression of conventional B-cell markers and strong expression of plasma cell markers. It is strongly associated with human immunodeficiency virus (HIV) and Epstein Barr virus infection, and shows an unusual tropism to the oral cavity. Herein we describe a patient with AIDS who presented with weight loss and dysphagia owing to a large gastroesophageal mass. His radiographic and endoscopic findings and long history of cigarette consumption suggested carcinoma. Biopsy demonstrated a poorly differentiated tumor stained negatively to routine lymphoid markers including CD20. However, gene rearrangement studies confirmed a B-cell process and a more detailed immunohistochemical analysis revealed the cells stained positively for CD138 (plasma cell antigen). These findings were diagnostic of PBL. Our report reviews the wide differential diagnosis of PBL and underscores the importance of a broad array of viral and molecular studies needed to establish this diagnosis. | Deepthi Mani Donald G Guinee Jr David M Aboulafia | 2008 | World Journal of Gastroenterology2008,14,27: | 4 |
| 3 | ZrO2-reinforeed Ni - P plate: An effective catalytic surface for hydrogen evolution 显示文摘 | Shibli S M A Dilimon V S Deepthi T | 2006 | Appl Surf Sei2006,253,4: | 1 |
| 4 | Improving the perform-ance of processing for small files in Hadoop : A case study of weatherdata analytics显示文摘 | PRASADG 1NAGESH H R DEEPTHI M | 2014 | International Journal of Computer Science & In-formation Technology2014,5,5: | 1 |
| 5 | Antioxidant activity of some substituted 1,2,4-triazo-5-thione schiff base显示文摘 | Valentina P Ilango K Deepthi M | 2009 | J Pharm Sci and Res2009,1,2: | 1 |
| 6 | Role ofnanofibrous poly (caprolactone) scaffolds in human mese-nchymal stem cell attachment and spreading for in vitrobone tissue engineeringresponse to osteogenic regulators显示文摘 | Binulal NS Deepthy M Selvamurugan N | 2010 | Tissue Eng Part A2010,16,2: | 1 |
| 7 | ZrO2-reinforced Ni-P plate: An effective catalytic surface for hydrogen evolution 显示文摘 | Shibli S M A Dilimon V S Deepthi T | 2006 | Applied Surface Science2006,253,4: | 1 |
| 8 | 查看详情显示文摘 | Deepthi M V Sharma M Sailaja R R N | | 0,,: | 1 |
| 9 | ZrO2-reinforced Ni-P plate: an effective catalytic surface for hydrogen evolution 显示文摘 | Shibli S M A Dilimon V S Deepthi T | 2006 | Appl Surf Sei2006,253,: | 1 |
| 10 | 查看详情显示文摘 | Sailaja R Deepthi M | | 0,,9: | 1 |
| 11 | Mechanical and thermal properties of coMPatibilized composites of polyethylene and esterified lignin 显示文摘 | Sailaja R R N Deepthi M V | 2010 | Materials and Design2010,31,9: | 1 |
| 12 | Channel estimation algorithm using an improved DFT for MIMO-OFDM systems显示文摘 | Deepthi Harika J Ramana Reddy M | 2012 | IOSRJECE2012,2,2: | 1 |
| 13 | Physicochemical and nanostrnctural properties of gelatin from uneconomical marine cornet fish (Fistularia petimba)显示文摘 | NAZEER R A KAVYA M DEEPTHI | 2013 | Food Science2013,22,1: | 1 |
| 14 | ZrO2 - reinforced Ni - P plate: An effective catalytic surface for hydrogen evolution 显示文摘 | SHIBLI S M A DIL1MON V S DEEPTHI T | 2006 | Applied Surface Science2006,253,4: | 1 |
| 15 | Mechanical and thermal properties of compatibilized composites of polyethylene and esterified lignin显示文摘 | Sailaja R R N Deepthi M V | 2010 | Materials&Design2010,31,9: | 1 |