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| 1 | Association of gene variants with susceptibility to type 2 diabetes among Omanis显示文摘AIM:To investigate the association of 10 known common gene variants with susceptibility to type 2diabetes mellitus(T2D)among Omanis.METHODS:Using case-control design,a total of992 diabetic patients and 294 normoglycemic Omani Arabs were genotyped,by an allelic discrimination assay-by-design TaqMan method on fast real time polymerase chain reaction system,for the following gene variants:KCNJ11(rs5219),TCF7L2(rs7903146),CDKAL1(rs10946398),CDKN2A/B(rs10811661),FTO(rs9939609 and rs8050136),IGF2BP2(rs4402960),SLC30A8(rs13266634)CAPN10(rs3792267)and HHEX(rs1111875).T2D patients were recruited from the Diabetes Clinic(n=243)and inpatients(n=749)at Sultan Qaboos Univesity Hospital(SQUH),Muscat,Oman.Adult control participants(n=294)were volunteers from the community and from those visiting Family Medicine Clinic at SQU,for regular medical checkup.The difficulty in recruiting Omani participants with no family history of diabetes was the main reason behind the small number of control participants in this study.Almost all volunteers questioned had a relativewith diabetes mellitus.Inspite of the small number of normoglycemic controls in this study,this sample was sufficient for detection of genes and loci for common alleles influencing T2D with an odds ratio of≥1.3reaching at least 80%power.Data was collected from June 2010 to February 2012.RESULTS:Using binary logistic regression analysis,four gene variants showed significant association with T2D risk:KCNJ11(rs5219,P=5.8×10^(-6),OR=1.74),TCF7L2(rs7903146,P=0.001,OR=1.46),CDKAL1(rs10946398,P=0.002,OR=1.44)and CDKN2A/B(rs10811661,P=0.020,OR=1.40).The fixation index analysis of these four gene variants indicated significant genetic differentiation between diabetics and controls{[KCNJ11(rs5219),P<0.001],[TCF7L2(rs7903146),P<0.001],[CDKAL1(rs10946398),P<0.05],[CDKN2A/B(rs10811661),P<0.05]}.The highest genotype variation%between diabetics and controls was found at KCNJ11(2.07%)and TCF7L2(1.62%).This study was not able to detect an association of T2D risk with gene variants of IGF2BP2(rs4402960),SLC30A8(rs13266634),CAPN10(rs3792267)and HHEX(rs1111875).Moreover,no association was found between FTO gene variants(rs9939609 and rs8050136)and T2D risk.However,T2D risk was found to be significantly associated with obesity(P=0.002,OR=2.22);and with the Waist-to-Hip ratio(n=532,P=1.9×10^(-7),OR=2.4),[among males(n=234,P=1.2×10^(-4),OR=2.0)and females(n=298,P=0.001,OR=6.3)].CONCLUSION:Results confirmed the association of KCNJ11(rs5219),TCF7L2(rs7903146),CDKAL1(rs10946398)and CDKN2A/B(rs10811661)gene variants with susceptibility to T2D among Omani Arabs. | Sawsan Al-Sinani Nicolas Woodhouse Ali Al-Mamari Omaima Al-Shafie Mohammed Al-Shafaee Said Al-Yahyaee Mohammed Hassan Deepali Jaju Khamis Al-Hashmi Mohammed Al-Abri Khalid Al-Rassadi Syed Rizvi Yengo Loic Philippe Froguel Riad Bayoumi | 2015 | World Journal of Diabetes2015，6，2： | 3 |
| 2 | Genital tuberculosis in adolescent girls from low socioeconomic status with acute ectopic pregnancy presenting at a tertiary care hospital in urban Northern India: are we missing an opportunity to treat?显示文摘 | Ananya Banerjee Shashi Prateek Sunita Malik Deepali Dhingra | 2012 | Archives of Gynecology and Obstetrics2012，，6： | 2 |
| 3 | Fault Pattern Diagnosis and Classification in Sensor Nodes Using Fall Curve显示文摘The rapid expansion of Internet of Things(IoT)devices deploys various sensors in different applications like homes,cities and offices.IoT applications depend upon the accuracy of sensor data.So,it is necessary to predict faults in the sensor and isolate their cause.A novel primitive technique named fall curve is presented in this paper which characterizes sensor faults.This technique identifies the faulty sensor and determines the correct working of the sensor.Different sources of sensor faults are explained in detail whereas various faults that occurred in sensor nodes available in IoT devices are also presented in tabular form.Fault prediction in digital and analog sensors along with methods of sensor fault prediction are described.There are several advantages and disadvantages of sensor fault prediction methods and the fall curve technique.So,some solutions are provided to overcome the limitations of the fall curve technique.In this paper,a bibliometric analysis is carried out to visually analyze 63 papers fetched from the Scopus database for the past five years.Its novelty is to predict a fault before its occurrence by looking at the fall curve.The sensing of current flow in devices is important to prevent a major loss.So,the fall curves of ACS712 current sensors configured on different devices are drawn for predicting faulty or non-faulty devices.The analysis result proved that if any of the current sensors gets faulty,then the fall curve will differ and the value will immediately drop to zero.Various evaluation metrics for fault prediction are also described in this paper.At last,this paper also addresses some possible open research issues which are important to deal with false IoT sensor data. | Mudita Uppal Deepali Gupta Divya Anand Fahd S.Alharithi Jasem Almotiri Arturo Mansilla Dinesh Singh Nitin Goyal | 2022 | Computers, Materials & Continua2022，，7： | 1 |
| 4 | Emergency preparedness and bioterrorism: a sur- vey of the Nebraska medical center staff and physicians 显示文摘 | Patricia A Lenaghan Philip W Smith Deepali Ganga-har | 2006 | Journal of Emergency Nursing2006，，5： | 1 |
| 5 | A comparison of lectronic waste recycling in Switzerland and in India 显示文摘 | DEEPALI SINHA-KHETRIWALA PHILIPP KRAEUCHIB MARKUS SCHWANINGER | 2005 | Environmental Impact Assessment Review2005，，25： | 1 |
| 6 | Motility Response to Insulin-like Growth Factor-I (IGF-I) in MCF-7 Cells is Associated with IRS-2 Activation and Integrin Expression显示文摘 | Xihong Zhang Sailaja Kamaraju Fumihiko Hakuno Tomohiro Kabuta Shin-Ichiro Takahashi Deepali Sachdev Douglas Yee | 2004 | Breast Cancer Research and Treatment2004，，2： | 1 |
| 7 | Global perspectives on Ewaste显示文摘 | Roll Widmer Heidi Oswald-Krapf Deepali Sinha-Khetriwal el al | 2005 | Env Impact Assess Rev2005，25，5： | 1 |
| 8 | Service level agreements in IP networks显示文摘 | Gaurav J Deepali S Shekhar V | 2002 | Information Management and Computer Security2002，10，4： | 1 |
| 9 | Bile duct changes in different etiologic types of end-stage chronic liver disease: a study on native explant livers显示文摘 | Deepali Jain Nabeen C Nayak | 2012 | Journal of Clinical Pathology2012，65，4： | 1 |
| 10 | Synthesis and characterization of polyim- ides and eo-polyimides having pendant benzoic acid moiety显示文摘 | Kulkarni M Kothawadea S Arabaleb G Mahesh K Sandeep K Girish Arabaleb Deepali W Vijayamohananb K Kulkarni R P Vernekar S P | 2005 | Polymer2005，46，： | 1 |
| 11 | Global perspectives on e-waste 显示文摘 | Rolf W Heidi O K Deepali S K | 2005 | Environmental Impact Assessment Review2005，25，43： | 1 |
| 12 | Oxidative absorption of hydrogen sulfide using an iron‐chelate based process: chelate degradation显示文摘 | Girish M. Deshmukh Aparna Shete Deepali M. Pawar | 2012 | J. Chem. Technol. Biotechnol2012，，3： | 1 |
| 13 | A comparison of electronic waste recycling in Switzerland and in India显示文摘 | Deepali Sinha-Khetriwala Philipp Kraeuchib Markus Schwaninger | 2005 | Environmental Impact Assessment Review2005，25，5： | 1 |
| 14 | Enhanced supercapacitance of multiwalled carbon nanotubes functionalized with ruthenium oxide显示文摘 | Girish A Deepali W Mahesh K | 2003 | Chemical Physics Letters2003，376，： | 1 |
| 15 | Enhanced expression of the shape Bacillus thuringiensis cry9Aa2 gene in transgenic plants by nucleotide sequence modification confers resistance to potato tuber moth显示文摘 | Andrew P. Gleave Deepali S. Mitra Ngaire P. Markwick Bret A.M. Morris Lesley L. Beuning | 1998 | Molecular Breeding1998，，5： | 1 |
| 16 | Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis显示文摘 | Zhou Yong Huang Xiangwei Hecker Louise Kurundkar Deepali Kurundkar Ashish Liu Hui Jin Tong-Huan Desai Leena Bernard Karen Thannickal Victor J | 2013 | Journal of Clinical Investigation2013，，3： | 1 |
| 17 | Utilization of industrial wastes and unprocessed micro-riflers for making coat effective mortars显示文摘 | AGARWAL S K Gulati Deepali | 2006 | Construction and Building Materials2006，20，10： | 1 |
| 18 | Global perspectives on e-waste显示文摘 | Rolf Widmer Heidi Oswald-Krapf Deepali Sinha-Khetriwal Max Schnellmann Heinz B?ni | 2005 | Environmental Impact Assessment Review2005，，5： | 1 |
| 19 | A comparison of electronic waste recycling in Switzerland and in India显示文摘 | Philipp Kraeuchib Markus Schwaninger | 2005 | Environmental Impact Assessment Review 252005，，： | 1 |
| 20 | Isolation and identification of a new antibacterial entity from the Antarctic cyanobacterium Nostoc CCC 537显示文摘 | Ravi K. Asthana Deepali Manoj K. Tripathi Arunima Srivastava Akhilesh P. Singh Sureshwar P. Singh Gopal Nath Ranjana Srivastava Brahm S. Srivastava | 2009 | Journal of Applied Phycology2009，，1： | 1 |
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