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| 1 | Fatigue behavior of Ti-6Al-4V cellular structures fabricated by additive manufacturing technique显示文摘Porous titanium and its alloys have been considered as promising replacement for dense implants, as they possess low elastic modulus comparable to that of compact human bones and are capable of providing space for in-growth of bony tissues to achieve a better fixation. Recently, the additive manufacturing(AM) method has been successfully applied to the fabrication of Ti-6 Al-4 V cellular meshes and foams.Comparing to traditional fabrication methods, the AM method offers advantages of accurate control of complex cell shapes and internal pore architectures, thus attracting extensive attention. Considering the long-term safety in the human body, the metallic cellular structures should possess high fatigue strength.In this paper, the recent progress on the fatigue properties of Ti-6 Al-4 V cellular structures fabricated by the AM technique is reviewed. The various design factors including cell shapes, surface properties, post treatments and graded porosity distribution affecting the fatigue properties of additive manufactured Ti-6 Al-4 V cellular structures were introduced and future development trends were also discussed. | Dechun Ren Shujun Li Hao Wang Wentao Hou Yulin Hao Wei Jin Rui Yang R.Devesh K.Misra Lawrence E.Murr | 2019 | Journal of Materials Science & Technology2019，35，2： | 15 |
| 2 | Resurrection of the Genus Leptomantis, with Description of a New Genus to the Family Rhacophoridae(Amphibia:Anura)显示文摘Genus Rhacophorus Kuhl and Van Hasselt, 1 822 is one of the most diverse genera of the family Rhacophoridae, and its taxonomy of genus Rhacophorus faces major challenges because of rapidly described new species and complex interspecies relations. In this study, we investigate the generic taxonomy within the genus Rhacophorus based on 1 972 bp of mitochondrial genes(12S rRNA, tRNA-val and 16S rRNA), containing 102 sequences from 58 species. The results reveal three well-supported and highly diverged matrilines that correspond with morphological characteristics and geographic distribution. Accordingly, we consider these three lineages as distinct genera: Rhacophorus sensu stricto, resurrected genus Leptomantis Peters, 1867, and the genus Zhangixalus gen. nov. | Dechun JIANG Ke JIANG Jinlong REN Jun WU Jiatang LI | 2019 | Asian Herpetological Research2019，10，1： | 8 |
| 3 | Kupffer cell restoration after partial hepatectomy is mainly driven by local cell proliferation in IL-6-dependent autocrine and paracrine manners显示文摘Kupffer cells(KCs),which are liver-resident macrophages,originate from the fetal yolk sac and represent one of the largest macrophage populations in the body.However,the current data on the origin of the cells that restore macrophages during liver injury and regeneration remain controversial.Here,we address the question of whether liver macrophage restoration results from circulating monocyte infiltration or local KC proliferation in regenerating livers after partial hepatectomy(PHx)and uncover the underlying mechanisms.By using several strains of genetically modified mice and performing immunohistochemical analyses,we demonstrated that local KC proliferation mainly contributed to the restoration of liver macrophages after PHx.Peak KC proliferation was impaired in Il6-knockout(KO)mice and restored after the administration of IL-6 protein,whereas KC proliferation was not affected in Il4-KO or Csf2-KO mice.The source of IL-6 was identified using hepatocyte-and myeloid-specific Il6-KO mice and the results revealed that both hepatocytes and myeloid cells contribute to IL-6 production after PHx.Moreover,peak KC proliferation was also impaired in myeloid-specific Il6 receptor-KO mice after PHx,suggesting that IL-6 signaling directly promotes KC proliferation.Studies using several inhibitors to block the IL-6 signaling pathway revealed that sirtuin 1(SIRT1)contributed to IL-6-mediated KC proliferation in vitro.Genetic deletion of the Sirt1 gene in myeloid cells,including KCs,impaired KC proliferation after PHx.In conclusion,our data suggest that KC repopulation after PHx is mainly driven by local KC proliferation,which is dependent on IL-6 and SIRT1 activation in KCs. | Yeni Ait Ahmed Yaojie Fu Robim M.Rodrigues Yong He Yukun Guan Adrien Guillot Ruixue Ren Dechun Feng Juan Hidalgo Cynthia Ju Fouad Lafdil Bin Gao | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 4 | Rational integration of defense and repair synergy on PEEK osteoimplants via biomimetic peptide clicking strategy显示文摘Polyetheretherketone(PEEK)has been widely used as orthopedic and dental materials due to excellent mechanical and physicochemical tolerance.However,its biological inertness,poor osteoinduction,and weak antibacterial activity make the clinical applications in a dilemma.Inspired by the mussel adhesion mechanism,here we reported a biomimetic surface strategy for rational integration and optimization of anti-infectivity and osteo-inductivity onto PEEK surfaces using a mussel foot proteins(Mfps)-mimic peptide with clickable azido terminal.The peptide enables mussel-like adhesion on PEEK biomaterial surfaces,leaving azido groups for the further steps of biofunctionalizations.In this study,antimicrobial peptide(AMP)and osteogenic growth peptide(OGP)were bioorthogonally clicked on the azido-modified PEEK biomaterials to obtain a dual-effect of host defense and tissue repair.Since bioorthogonal clicking allows precise collocation between AMP and OGP through changing their feeding molar ratios,an optimal PEEK surface was finally obtained in this research,which could long-term inhibit bacterial growth,stabilize bone homeostasis and facilitate interfacial bone regeneration.In a word,this upgraded mussel surface strategy proposed in this study is promising for the surface bioengineering of inert medical implants,in particular,achieving rational integration of multiple biofunctions to match clinical requirements. | Meng Li Jiaxiang Bai Huaqiang Tao Li Hao Weiling Yin Xiaoxue Ren Ang Gao Ning Li Miao Wang Shiyuan Fang Yaozeng Xu Liang Chen Huilin Yang Huaiyu Wang Guoqing Pan Dechun Geng | 2022 | Bioactive Materials2022，7，2： | 2 |
| 5 | Taxonomic Revision of Raorchestes menglaensis(Kou,1990)(Amphibia:Anura),with Descriptions of Two New Species from Yunnan,China显示文摘Raorchestes is a group of Bush frogs mainly distributed in South and Southeast Asia that are poorly recognized by morphological criteria.We recognize the true R.menglaensis(Kou) based on 10 specimens newly collected from the type locality.An expanded description is also provided,and we delist the recently reported record,R.parvulus(Boulenger) from China.Combing with morphological and molecular data,two new species are respectively described from Menghai and Lvchun,Yunnan,China.Raorchestes hillisi sp.nov.is distinguished from all other congeners by the following combination of morphological characters:(1) small body sized(males 15.9-17.7 mm,n=7;female 17.5 mm,n=1);(2) head longer than wide;(3) snout longer than eye diameter;(4) the tip of upper jaws slightly notched;(5) internasal space slightly less than interorbital space;(6) tympanum distinct;(7)fingers lacking lateral dermal fringe;(8) outside of toe Ⅰ and both sides of toe Ⅱ lacking lateral dermal fringe,other toes having weak lateral dermal fringes;(9) rudimentary web on toes;(10) lacking a series of tubercles along the outer sides of forearm and foot;(11) discs of fingers and toes not orange.Raorchestes huanglianshan sp.nov.is distinguished from all other congeners by the following combination of morphological characters:(1) small body size(males 17.0-19.6 mm,n=12;female 21.5 mm,n=1);(2) head slightly wider than long or equal;(3) snout longer than eye diameter;(4)the tip of upper jaws slightly notched;(5) internasal space distinctly less than interorbital space(6) tympanum distinct;(7) fingers lacking lateral dermal fringe;(8) toes lacking lateral dermal fringe;(9) rudimentary web on toes;(10)lacking a series of tubercles along the outer sides of forearm and foot;(11) discs of all fingers and toes orange or parts of them orange in life. | Ke JIANG Jinlong REN Jian WANG Junfeng GUO Zeng WANG Yonghong LIU Dechun JIANG Jiatang LI | 2020 | Asian Herpetological Research2020，11，4： | 1 |
| 6 | A power manager system with 78% efficiency for high-voltage triboelectric nanogenerators显示文摘Dear editor,The Internet of Things(Io T)refers to a growing trend to create relatively simple devices that interconnect and share data independent of computers or human intervention[1].In these applications,a continuous power supply system is necessary.There are many research studies that focus on environmental energy for self-powered portable electronics,which can minimize battery consumption and extend cell life.This is the | Lichuan LUO Dechun BAO Wuqi YU Zhaohua ZHANG Tianling REN | 2017 | Science China(Information Sciences)2017，60，2： | 0 |
| 7 | Bi-continuous Mg-Ti interpenetrating-phase composite as a partially degradable and bioactive implant material显示文摘Mg(and Mg alloys)and Ti(and Ti alloys)are two important classes of metallic implant materials which are respectively completely degradable and non-degradable after implantation.Making composites composed of them offers the promise for combining their property advantages for bone repair.Here,we present a Mg-Ti composite fabricated by pressureless infiltration of pure Mg melt into 3D printed Ti scaffold,and demonstrate a potential of the composite for use as new partially degradable and bioactive implant materials.The composite has such architecture that the Mg and Ti phases are topologically bicontinuous and mutually interspersed in 3D space,and exhibits several advantages over its constituents,such as higher strengths than as-cast pure Mg and Ti scaffold along with lower Young’s modulus than dense Ti.Additionally,the degradation of Mg phase may induce the formation and ingrowth of new bone tissues into the Ti scaffold to form mechanical interlocking between them;in this process,the Ti scaffold provides constant support and Young’s modulus adaptively decreases toward that of bone.Despite the accelerated corrosion than pure Mg,the composite remains non-cytotoxic and does not cause obvious adverse reactions after implantation as revealed by in vitro and in vivo experiments.This study may offer a new possibility for combining mechanical durability and bioactivity in implant materials,and allow for customized and targeted design of the implant. | Chenxi Dou Mingyang Zhang Dechun Ren Haibin Ji Zhe Yi Shaogang Wang Zengqian Liu Qiang Wang Yufeng Zheng Zhefeng Zhang Rui Yang | 2023 | Journal of Materials Science & Technology2023，，15： | 0 |
| 8 | Morphology and Histochemistry of Infralabial Glands of Two Species in the Slug-Eating Family Pareidae(Reptilia:Serpentes)显示文摘Pareidae and Dipsadidae,two independently evolved taxa in the Serpentes lineage,both feed exclusively on terrestrial mollusks(snails and slugs).Dipsadid snakes developed hypertrophic infralabial glands in their lower jaw,which are thought to be associated with their specialized feeding behaviors.However,whether a similar gland exists in pareid snakes is unknown.In this study,we examined the morphological characteristics of the infralabial glands in Pareas berdmorei and Pareas chinensis based on comparative anatomical,histochemical,and histopathological analysis.Our results demonstrated that both Pareas species had similar hypertrophied infralabial glands in the lower jaw,which consisted of tubules with mucinous properties and seromucous acini.The secretory granules of the seromucous cells also showed high electron density.The cytoplasm was rich in rough endoplasmic reticulum,mitochondria,and Golgi apparatus,suggesting that these cells may secrete protein substances,and play an important role in digesting mollusks.This study provides evidence of morphological convergence between Pareidae and Dipsadidae due to specialized diet adaptation,which will be the foundation for prospective functional research. | Dan WANG Jinlong REN Ke JIANG Wei WU Changjun PENG Hussam ZAHER Dechun JIANG Jiatang LI | 2022 | Asian Herpetological Research2022，13，3： | 0 |
| 9 | A power management circuit with 50%efficiency and large load capacity for tribo-electric nanogenerator显示文摘Recently, triboelectric nanogenerators(TENGs), as a collection technology with characteristics of high reliability, high energy density and low cost, has attracted more and more attention. However, the energy coming from TENGs needs to be stored in a storage unit effectively due to its unstable ac output. The traditional energy storage circuit has an extremely low energy storage efficiency for TENGs because of their high internal impedance.This paper presents a new power management circuit used to optimize the energy using efficiency of TENGs, and realize large load capacity. The power management circuit mainly includes rectification storage circuit and DC–DC management circuit. A rotating TENG with maximal energy output of 106 m W at 170 rpm based on PCB is used for the experimental verification. Experimental results show that the power energy transforming to the storage capacitor reach up to 53 m W and the energy using efficiency is calculated as 50%. When different loading resistances range from 0.82 to 34.5 k are connected to the storage capacitor in parallel, the power energy stored in the storage capacitor is all about 52.5 m W. Getting through the circuit, the power energy coming from the TENGs can be used to drive numerous conventional electronics, such as wearable watches. | Dechun Bao Lichuan Luo Zhaohua Zhang Tianling Ren Tianling RenTianling Ren | 2017 | Journal of Semiconductors2017，38，9： | 0 |
| 10 | Evolution of Phenotype and Mitochondrial Genome Reveals Limbless and Body-elongated Squamates may Change Their Energy Basis for Locomotion显示文摘Limb reduction in Squamata present the dramatic characteristic to focus and usually accompanied with particularly morphological modifications, impacting tremendous locomotion changing and might generate different energy requirement. Herein, we combined both morphological and mitochondrial genomic data to explore the evolution of phenotypic transformation and mitochondrial genome of limbless and body-elongated squamates. We collected phenotypic measurements of 503 individuals, representing limbed or limbless taxa across all major lineages in Squama ta to investiga te the morphological correla tions with limb-reduction. Furthermore, we provided the mitochondrial genome of the representative limbless and elongated species Dibamus bourreti(Angel, 1935) to detect selective constraints on limbless clades with published mitogenomes of other squa ma te reptiles. Our results evidenced tha t body elongation had certain negative relationship with limbreduction in Squamata lineage and Lacertilia lineage(R = –0.495, P < 2.2 e-16;R= –0.332, P = 1.1 e-13, respectively), while tail length showed slight correlation in both clades(R = 0.156, P = 4.3 e-04;R= 0.192, P = 2.1 e-05, respectively). Besides, detection demonstrated that ATP6 has experienced accelerated evolution among limbless lineages, suggesting selective pressure on mitogenomes may play an essential role in energy disparity for locomotion of limbed and limbless squamates. | Zeng WANG Wei WU Jinlong REN Changjun PENG Dechun JIANG Jiatang LI | 2021 | Asian Herpetological Research2021，12，2： | 0 |
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