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24篇 您的检索式：作者名="David PL"

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	题名	作者	年代	出处	被引量
1	miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus显示文摘AIM: To investigate miR-200 family expression in Barrett's epithelium, gastric and duodenal epithelia, and esophageal adenocarcinoma. METHODS: Real-time reverse transcriptase-polymerase chain reaction was used to measure miR-200, ZEB1 and ZEB2 expression. Ingenuity Pathway Analysis of miR-200 targets was used to predict biological outcomes. RESULTS: Barrett's epithelium expressed lower levels of miR-141 and miR-200c than did gastric and duodenal epithelia (P < 0.001). In silico analysis indicated roles for the miR-200 family in molecular pathways that distinguish Barrett's epithelium from gastric and duodenalepithelia, and which control apoptosis and proliferation. All miR-200 members were downregulated in adenocarcinoma (P < 0.02), and miR-200c expression was also downregulated in non-invasive epithelium adjacent to adenocarcinoma (P < 0.02). The expression of all miR-200 members was lower in Barrett's epithelium derived high-grade dysplastic cell lines than in a cell line derived from benign Barrett's epithelium. We observed signif icant inverse correlations between miR-200 family expression and ZEB1 and ZEB2 expression in Barrett's epithelium and esophageal adenocarcinoma (P < 0.05). CONCLUSION: miR-200 expression might contribute to the anti-apoptotic and proliferative phenotype of Barrett's epithelium and regulate key neoplastic processes in this epithelium.	Cameron M Smith David I Watson Mary P Leong George C Mayne Michael Z Michael Bas PL Wijnhoven Damian J Hussey	2011	World Journal of Gastroenterology2011，17，8：	13
2	Human retinal pigment epithelium cell changes and ex- pression of αB-crystallin: A biomarker for retinal pigment epi- thelium cell change in age-related macular degeneration 显示文摘	Soma DE David M Salero E Lederman PL Temple S Stern JH	2007	Arch Ophthalmol2007，125，5：	1
3	An evaluation of process and out comes from learning through reflective practice groups on a post -registration nursing course显示文摘	Hazel PL David BL Dorothy AS	2000	J of Adv Nur2000，31，3：	1
4	Xenotransplantation of cells and tissues: application to a range of diseases, from diabetes to Alzheimer's显示文摘	Robert PL David KCC	1998	Mole Med Tod1998，4，1：	1
5	An evaluation of process and outcomes from learning through reflective practice groups on a post-registration nursing course显示文摘	Hazel PL David BL Dorothy AS	2000	J of Adv Nur2000，31，3：	1
6	The risk of lymphoma and im- munomodulators in patients with inflammatory bowel diseases:results from a population-based cohort in Eastern Europe显示文摘	Lakatos PL Lovasz BD David G	2013	Journal of Crohn & colitis2013，7，5：	1
7	An evaluation of process and outcomes from learning through reflective practice groups on a post-registration nursing course显示文摘	Hazel PL David BL Dorothy AS	2000	J of Adv Nur2000，31，3：	1
8	Replicating a Colles fracture in an excised radius: Revisiting testing proto- cols显示文摘	David WW Derek PL Gary SB	2012	Journal of Biomechanics2012，45，6：	1
9	Teaching inpatient communication skills to medical students显示文摘	David PL Larry B	2005	Academic Medicine2005，，2：	1
10	Measuring patientstrust inPhysicians when assessing quality of care 显示文摘	David HT Mark AH Gregory PL	2004	Health Affairs (Millwood)2004，，4：	1
11	Association of adherence to therapy and complementary and alternative medicine use with demographic factors and disease phenotype in Patients with inflammatory bowel disease显示文摘	Lakatos PL Czegledi Z David G	2010	J Crohns Colitis2010，4，3：	1
12	Adjunctive platelet glycoprotein Ⅱb/Ⅲa receptor inhibition with tirofiban before primary angioplasty improves anglographic outcomes: results of the tirofiban given in the emergency room before primary angioplasty (TIGER-PA) pilot trial 显示文摘	David PL Niall AH Bonnie LH	2003	Circulation2003，107，11：	1
13	Hypoglossal nerve transfer for laryngeal reinnervation: apreliminary study显示文摘	Randal C Paniello PL J David D	1999	Ann Otol Rhinol Lamgol1999，108，3：	1
14	Sacral Nerve Stimulation for the Treatment of Severe Faecal Incontinence: Results After 10 Years Experience显示文摘	M. Dolores Ruiz Carmona José Martín Arévalo David Moro Valdezate Vicente Plá Martí Félix Checa Ayet	2014	Cirugía Espa?ola (English Edition)2014，，：	1
15	Regulatory T cells attenuate mycobacterial stasis in alveolar and blood-derived macrophages from patients with tuberculosis显示文摘	Semple PL Binder AB Davids M		0，，：	1
16	Aneurysms of the distal anterior cerebral artery:results in consecutively managed patients显示文摘	Stephen PL Gary GF	2007	Neurosurgery2007，60，：	1
17	Sinistral portal hyper-tension splenectomy or expectant management显示文摘	John PL David MN Duabe I	1993	AnnSurg1993，217，1：	1
18	Regulatory T cells attenuate mycobacterial stasis in alveolar and blood-derived macrophages from patients with tuberculosis显示文摘	Semple PL Binder AB Davids M	2013	Am J Respir Crit Care Med2013，187，11：	1
19	Sex-specific migration patterns in Central Asian populations, revealed by analysis of Y-Chromosome short tandem repeats and mtDNA 显示文摘	Anna PL Francesc C David C	1999	Am J Hum Genet1999，65，：	1
20	College students' perceptions about alcohol and consensual sexual behavior:Alcohol leads to sex显示文摘	Kristen PL David WP Melissa AL William HG		0，，01：	1

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