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44篇 您的检索式:作者名="Darja"
    题名 作者 年代 出处 被引量
1Estrogen-mediated downregulation of HIF-1αsignaling in B lymphocytes influences postmenopausal bone loss显示文摘In the bone marrow, B cells and bone-resorbing osteoclasts colocalize and form a specific microenvironment. How B cells functionally influence osteoclasts and bone architecture is poorly understood. Using genetically modified mice and highthroughput analyses, we demonstrate that prolonged HIF-1α signaling in B cells leads to enhanced RANKL production and osteoclast formation. In addition, deletion of HIF-1α in B cells prevents estrogen deficiency-induced bone loss in mice.Mechanistically, estrogen controls HIF-1α protein stabilization through HSP70-mediated degradation in bone marrow B cells.The stabilization of HIF-1α protein in HSP70-deficient bone marrow B cells promotes RANKL production and osteoclastogenesis.Induction of HSP70 expression by geranylgeranylacetone(GGA) administration alleviates ovariectomy-induced osteoporosis.Moreover, RANKL gene expression has a positive correlation with HIF1 A expression in human B cells. In conclusion, HIF-1αsignaling in B cells is crucial for the control of osteoclastogenesis, and the HSP70/HIF-1α axis may serve as a new therapeutic target for osteoporosis.Xianyi Meng Zhen Lin Shan Cao Iga Janowska Koshiro Sonomoto Darja Andreev Knab Katharina Jinming Wen Karl Xaver Knaup Michael Sean Wiesener Gerhard Krönke Marta Rizzi Georg Schett Aline Bozec 2022Bone Research2022,10,2:6
2Engineering bone tissue from human embryonic stem cells显示文摘Darja Marolt 2012Proc Natl Acad Sci U S A2012,109,22:1
3A two-step synthesis of NiZn-W hexaferrites显示文摘Darja Lisjak Andrej Znidarsic Anna Sztanislav 0,,10:1
4The mechanism of the low-temperature formation of barium hexaferrite 显示文摘LISJAK Darja DROFENIK Miha 2007Journal of the European Ceramic Society2007,27,16:1
5The low-Temperature Sintering of M-Type Hexaferrites显示文摘Darja L 2012Journal of The European Ceramic Society2012,32,:1
6The Low-Temperature Sintering Mechanism of Sr-Hexaferrite Using the Addition of CuO 显示文摘Darja L Richard L 2012The American Ceramic Society2012,95,10:1
7β-cyelodextrin as retarding reagent in polyaerylonitrile dyeing 显示文摘Bojana Voncina Vera Vivod Darja Jau$ovec 2007Dyes and Pigments2007,74,3:1
8Doubtful and discordant results in fluorescent antibody test for rabies diagnosing显示文摘Peter Hostnik Marjeta Strancar Darja Barlic-Maganja 2001Veterinarski Arhiv2001,71,2:1
9A comparative study of the electnochemical deposition kinetics of iron-palladium alloys on a flat electrode and in a porous alumina template显示文摘Kostevsek Nina Rozman Kristina Zuzek Pecko Darja el al 2014Electrochimica Acta2014,125,12:1
10The corrosion behavior of Cr-(CN) PVD hard coatings deposited on various substrates显示文摘Darja Kek Merl Peter Panjian Mila Cekada 2004Electrochimica Acta2004,49,:1
11Highly Aensitive One-tube RT-PCR and Microplate Hybridization Assay for the Detection and for the Discrimination of Classical Swine Fever Virus from other Pestivirus显示文摘Darja Barli-Maganja Joe Grom 2001Journal of Virological Methods2001,95,:1
12Expression of bone resorption genes in osteoarthritis and in osteoporosis显示文摘Darja Bitenc Logar Radko Komadina Janez Pre?elj Barbara Ostanek Zoran Tro?t Janja Marc 2007Journal of Bone and Mineral Metabolism2007,,4:1
13Effects of Pamidronate on Human Alveolar Osteoblasts In Vitro显示文摘Darja Marolt Matthew Cozin Gordana Vunjak-Novakovic Serge Cremers Regina Landesberg 2012Journal of Oral and Maxillofacial Surgery2012,,5:1
14Water solubility in haplobasaltic melts 显示文摘 Harald Behrens 2003European Journal of Mineralogy2003,15,5:1
15Association between neurological signs and developmental outcome:Pilot results in preterm group显示文摘Darja P P Jana K 2009Croatian Medical Journal2009,50,4:1
16Computer simulation of needle and take-up lever mechanism using the ADAMS software package显示文摘 Karl Gotlih 2003Fibres & Textiles in Eastern Europe2003,11,4:1
17β-Cyclodextrin as Retarding Reagent in Polyacrylonitrile Dyeing显示文摘Voneina B Vivod V Darja J 2007Dyes and Pigments2007,74,3:1
18Drape behaviour of seamed fabrics显示文摘SIMONA J DARJA 2 2007Fibers and Polymers2007,8,5:1
19Cell death: apoptosis versus necrosis显示文摘DARJA K ABRAHAM M ROSARIO S 2002International Journal Of Oncology2002,21,:1
20Impedance and XPS study of benzotriazole films formed on copper,copper-zinc alloys and zinc in chloride solution显示文摘Tadeja K Darja Kek M Ingrid M 2008Corrosion Science2008,50,7:1
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