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| 1 | Acute infectious osteomyelitis in children: new treatment strategies for an old enemy显示文摘Background Acute osteomyelitis still represents a significant clinical challenge,with an increasing incidence in paediatric population.A careful assessment and a rapid diagnosis with proper timing and choice of empirical antimicrobial therapy are necessary to avoid sequelae.The initial treatment should consist of empirical antibiotic therapy,to cover the major responsible pathogens in each age group.Data sources We made a literature search with PubMed and Cochrane database from 2000 to 2019 in English,French,and Spanish languages using the key words'osteomyelitis,children,clinical,diagnosis,and treatment'.Results The child's clinical features,age,and the microbiological profile of the geographic area should be evaluated for diagnosis and in the choice of antibiotic treatment.Latest data suggest the administration of intravenous antibiotics for a short period,with subsequent oral therapy,according to the improvement of clinical status and inflammatory markers.For children older than 3 months,the shift to oral medications is already possible after a short course of intravenous therapy,until recovery.The timing for the shift from cefazolin to cephalexin or cefuroxime,intravenous clindamycin to oral clindamycin,and intravenous ceftriaxone+oxacillin to oral equivalents will be decided according to the improvement of clinical status and inflammatory markers.We also present the approach to osteomyelitis due to difficult pathogens,such as Methicillin-resistant Staphylococcus aureus(MRSA)and Panton-Valentine leukocidin(PVL)-positive S.aureus infections.Conclusion In this review,we present the current approach to the clinical diagnosis and management of osteomyelitis in childhood,with an update on recent recommendations,as a useful instrument to understand the rationale of antibiotic therapy. | Sabrina Congedi Chiara Minotti Carlo Giaquinto Liviana Da Dalt Daniele Don | 2020 | World Journal of Pediatrics2020，16，5： | 8 |
| 2 | The Preoperative Manometric Pattern Predicts the Outcome of Surgical Treatment for Esophageal Achalasia显示文摘 | Renato Salvador Mario Costantini Giovanni Zaninotto Tiziana Morbin Christian Rizzetto Lisa Zanatta Martina Ceolin Elena Finotti Loredana Nicoletti Gianfranco Da Dalt Francesco Cavallin Ermanno Ancona | 2010 | Journal of Gastrointestinal Surgery2010，，11： | 2 |
| 3 | Nasal lavage leukotrienes in infants with RSV bronchiolitis 显示文摘 | Dalt L D Callegaro S Carraro S | 2007 | Pediatr Allergy Immunol2007，18，2： | 1 |
| 4 | Too Busy to Show up?An Analysis of Directors’Absences显示文摘 | Jiraporn P Wallace N Davidson III Peter Da Dalt Yixi Ning | 2009 | The Quarterly Review of Economics and Finance2009，，49： | 1 |
| 5 | Nasal Lavage Leukotrienes in infants with RSV bronchiolitis显示文摘 | Da Dalt L Callegaro S Carraro S | 2007 | Pediatr Allergy Immunol2007，18，2： | 1 |
| 6 | Nasal lavage leukotrienes in in- fants with RSV bronchiolitis 显示文摘 | da Dalt L Callegaro S Carraro S | 2007 | Pediatr Allergy Immunol2007，18，2： | 1 |
| 7 | On the Jitter requirements of the sampling clock for analog-to-digital converters 显示文摘 | DALT N D HARTENECK M SANDNER C | 2002 | IEEE on Circuits and System-Ⅰ: Fundamental Theory and Applications2002，49，9： | 1 |
| 8 | Nasal lavage leukotrienes in infants with RSV bronchiolitis显示文摘 | Dalt LD Callegaro S Carraro S | | 0，，02： | 1 |
| 9 | On the jitter requirements of the sampling clock for aim-og-to-digiital converters显示文摘 | Da Dalt N Harteneck M et a1 | 2002 | IEEE Transactions On Circuits and Systems I:Fundamental Theory and Applications2002，49，9： | 1 |
| 10 | The use of an insulin bolus in lowdose in sulin infusion for pediatric diabetic ketoacidosis显示文摘 | Lindsay R Dalte R G | 1989 | Pediatr Emdrg Care1989，5，2： | 1 |
| 11 | Pediatric Emergency Care Applied Research Network head injury clinical prediction rules are reliable in practice 显示文摘 | Schonfeld D Bressan S Da Dalt L | 2014 | Arch Dis Child2014，99，5： | 1 |
| 12 | Nasal lavage leukotrienes in infants with bronchiolitis显示文摘 | da Dalt L Cal legaro S Car rao S | 2007 | Pediatr Allergy Immunol2007，18，2： | 1 |
| 13 | Nasal lavage leuk- otrienes in infants with RSV bronehiolitis显示文摘 | Da Dalt L Callegaro S Carraro S | 2007 | Pediatr All- ergy Immunol2007，18，2： | 1 |
| 14 | Nasal lavageleukotrienes in infants with RSV bronchiolitis 显示文摘 | Da Dalt L Callegaro S Carraro S | 2007 | PediatrAllergy Immunol2007，18，2： | 1 |
| 15 | A model of quality assurance and quality improvement for post-graduate medical education in Europe显示文摘 | Da Dalt L Callegaro S Mazzi A | 2010 | Med Teach2010，32，2： | 1 |
| 16 | On the jitter requirements of the sampling clock for analog-to-digital conver-ters显示文摘 | N Da Dalt | 2002 | IEEE Trans on Circuits and Systems Ⅰ2002，49，9： | 1 |
| 17 | Changes in lipid and protein during starvation and the moulting cycle in the tiger prawn Penaeus esculencus显示文摘 | Barclay M C Dalt W Smith D M | 1983 | J Exp Mar Biol Ecol1983，68，： | 1 |
| 18 | Treatment of bronchiolitis: state of the art显示文摘 | Da Dalt L Bressan S Martinolli F | 2013 | Early Hum Dev2013，89，1： | 1 |
| 19 | Nasal lavage leukotrienes in infants with RSV bronchiolitis 显示文摘 | Da Dalt L Callegaro S Carraro S | 2007 | Pediatr Allergy Immunol2007，18，2： | 1 |
| 20 | Intrauterine adhesions after manual vacuum aspiration for early pregnancy failure显示文摘 | Dalt on VK Saunders NA Harris LH | 2006 | Fertil Steril2006，85，6： | 1 |
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