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| 1 | ISUOG实用指南(更新版):胎儿心脏超声筛查指南解读显示文摘本文是对以往国际妇产科超声学会(The International Society of Ultrasound in Obstetrics and Gynecology,ISUOG)发表的关于孕中期胎儿心脏超声筛查常规[1]的修订和更新版本,为产前超声筛查先天性心脏病的最新观点。新的ISUOG指南与其他指南相一致,推荐将超声筛查胎儿心脏的左右心室流出道观和四腔观列入常规筛查。 | 孙夫丽 吴青青 王莉 Carvalho JS Allan LD | 2014 | 中华医学超声杂志(电子版)2014,11,4: | 25 |
| 2 | 接受治疗的老年高血压患者的血压、抗高血压药物应用、衰弱指标与严重摔伤风险的关系显示文摘一些研究表明,降压药物、低收缩压和舒张压与跌倒风险增加相关。许多老年人表现出衰弱的指征,这可能会增加跌倒的风险。该研究纳入脑卒中地区和种族差异原因(the reasons for geographic and racial differences in stroke,REGARDS)研究中年龄≥65岁的受试者5236例,探索收缩压、舒张压、抗高血压药物类别数量以及衰弱指标与严重跌倒损伤风险的关系, | 刘莉 叶鹏 Bromfield SG Ngameni CA Colantonio LD Bowling CB Shimbo D Reynolds K Safford MM Banach M Toth PP Muntner P | 2017 | 中华高血压杂志2017,25,8: | 19 |
| 3 | Irritable bowel syndrome and functional constipation management with integrative medicine: A systematic review显示文摘BACKGROUND Irritable bowel syndrome(IBS)and functional constipation(FC)are two commonly encountered functional gastrointestinal disorders in clinical practice and are usually managed with Western medicines in cooperation with traditional Chinese medicine(TCM)interventions.Although clinical practice guidelines(CPGs)have been developed to assist clinicians with their decisions,there are still gaps in management with regard to integrative medicine(IM)recommendations.AIM To comprehensively review the currently available CPGs and to provide a reference for addressing the gaps in IBS and FC management.METHODS We searched mainstream English and Chinese databases and collected data from January 1990 to January 2019.The search was additionally enriched by manual searches and the use of publicly available resources.Based on the development method,the guidelines were classified into evidence-based(EB)guidelines,consensus-based(CB)guidelines,and consensus-based guidelines with no comprehensive consideration of the EB(CB-EB)guidelines.With regard to the recommendations,the strength of the interventions was uniformly converted to a 4-point grading scale.RESULTS Thirty CPGs met the inclusion criteria and were captured as data extraction sources.Most Western medicine(WM)CPGs were developed as EB guidelines.All TCM CPGs and most IM CPGs were identified as CB guidelines.Only the 2011 IBS and IM CPG was a CB-EB set of guidelines.Antispasmodics and peppermint oil for pain,loperamide for diarrhea,and linaclotide for constipation polyethylene glycol and lactulose as osmotic laxatives,bisacodyl and sodium picosulfate as stimulant laxatives,lubiprostone and linaclotide as prosecretory agents,and prucalopride were strongly recommended or recommended in FC.TCM interventions were suggested based on pattern differentiation,while the recommendation level was considered to be weak or insufficient.CONCLUSION WM CPGs generally provide a comprehensive management algorithm,although there are still some gaps that could be addressed with TCM.Specific high-quality trials are needed to enrich the evidence. | Liang Dai Linda LD Zhong Guang Ji | 2019 | World Journal of Clinical Cases2019,7,21: | 14 |
| 4 | 西双版纳尚勇自然保护区野生印支虎及其三种主要有蹄类猎物种群现状调查显示文摘中国野生印支虎及其猎物种群状况的野外实地研究一直处于空白。本研究使用足迹鉴别法、粪堆计数法,首次对西双版纳尚勇自然保护区野生印支虎种群数量现状及该区域内的虎猎物种群状况进行了调查研究。结果显示:2004—2009年间,确认西双版纳保护区存在3只成年印支虎个体(2雌1雄),西双版纳尚勇保护区拥有比较丰富的有蹄类种群,其中虎的主要猎物:水鹿平均密度为7.63(7.40—9.23)只/km2;赤麂平均密度为17.39(11.33—24.94)只/km2,野猪平均密度为10.26(7.69~14.51)只/km2,该区域虎猎物生物量为1715.74kg,/km2。本研究还探讨了该区域印支虎种群的保护前景以及中国境内开展虎种群调查的适用办法等。 | 冯利民 王利繁 王斌 James LD Smith 张立 | 2013 | 兽类学报2013,33,4: | 14 |
| 5 | 常规脂蛋白检测和载脂蛋白在心血管病预测中的比较显示文摘总胆固醇和高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)测量值对于心血管病风险评估至关重要,但对于其他脂质用于风险预测的效用一直存在争议。该研究纳入来自英国生物银行(Biobank)的无基线心血管病、未服用他汀类药物、有相关的脂质指标(n=346 686)的受试者。 | Welsh C Celis-Morales CA Brown R Mackay DF Lewsey J Mark PB Gray SR Ferguson LD Anderson JJ Lyall DM Cleland JG Jhund PS Gill J MR Pell JP Sattar N Welsh P 刘青(译) 叶鹏(摘、审校) | 2019 | 中华高血压杂志2019,27,7: | 10 |
| 6 | 饲用山羊豆显示文摘饲用山羊豆(Galega orientalis Lam.)源自高加索地区,在爱沙尼亚境内生长良好,对气候条件温和及北方地区是一种极具潜力的豆科牧草。饲用山羊豆可持续高产,其最大特点是在苜蓿种子成熟不良地区,能够获得稳定、较高的种子产量。 | H.Nómmsalu H.Meripóld J.Metlitskaja H.Raig 曾彦军 | 1998 | 国外畜牧学(草原与牧草)1998,,1: | 8 |
| 7 | Would integrated Western and traditional Chinese medicine have more benefits for stroke rehabilitation? A systematic review and meta-analysis显示文摘Background Stroke is a major cause of death or long-term disability worldwide.Many patients with stroke receive integrative therapy consisting of Western medicine(WM)and routine rehabilitation in conjunction with Chinese medicine(CM),such as acupuncture and Chinese herbal medicine.However,there is no available evidence on the effectiveness of the combined use of WM and CM interventions in stroke rehabilitation.Aims The purpose of this meta-analysis is to evaluate the results of all individual studies to assess the combined use of CM and WM in stroke rehabilitation compared with WM only.Methods The Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines were followed.MEDLINE,EMBASE,Cochrane and China National Knowledge Infrastructure(CNKI)were searched.The included outcomes were dependency,motor function,depression and swallowing function.Subgroup analysis was performed,and publication bias was assessed using funnel plots.Summary of review 58 studies and 6339 patients were included in the meta-analysis.Subgroup analysis revealed that combined therapy comprising both acupuncture and WM had a superior effect on improving dependency and swallowing function compared with standard WM therapy alone.Potential superiority of combined therapy comprising CM and WM in improving depression compared with standard WM therapy was also found.Conclusions Our results indicate that the combined use of CM and WM could be more efficacious in stroke rehabilitation compared with the use of WM therapy alone.However,most studies were short in duration(2 to 4 weeks)and prone to different types of biases,which prevents making any conclusion regarding the long-term effects and raises concerns regarding true efficacy in context of high likelihood of Hawthorn bias.So,more randomised controlled trials with more rigorous design and longer duration of treatment and follow-up need to be conducted to compare WM alone versus WM and CM combined. | Linda LD Zhong Ya Zheng Alexander Y Lau Norman Wong Liang Yao Xingyao Wu Tengteng Shao Zhenxing Lu Huijuan Li Chun Sum Yuen Jianwen Guo Suzanne Lo Janita Chau Kam Wa Chan Bacon Fung Leung Ng Zhaoxiang Bian Edwin Chau-leung Yu | 2022 | Stroke & Vascular Neurology2022,7,1: | 7 |
| 8 | Evidence-Based Chinese Medicine Clinical Practice Guideline for Stomach Pain in Hong Kong显示文摘Stomach pain in Chinese medicine(CM) is a very common disorder in clinical practice and it has been listed as one of the pilot three conditions in Hong Kong to develop evidence-based CM clinical practice guidelines(CM CPGs). The aim of this stomach Pain CPG is to summarize the treatment methods of stomach pain with CM and evaluate reasonably, then to guide local licensed CM practitioners and provide beneficial reference for social medical decision makers and patients. In this manuscript, we defined stomach pain in CM and the category of chronic gastritis in Western medicine. The clinical manifestation, CM pattern classification, and CM intervention including herbal medicine treatment based on pattern differentiation, symptomatic treatment, acupuncture treatment, regulation and nursing were illustrated. | ZHONG Linda LD SHI Nan-nan DAI Liang ZIEA Tat Chi NG Bacon TANG Xu-dong BIAN Zhao-xiang LU Ai-ping | 2017 | Chinese Journal of Integrative Medicine2017,23,10: | 6 |
| 9 | 文献快报(22):儿童中增加运动、减少静坐、提高蔬果摄入--“积极生活5年”学校为基础的群组随机对照实验显示文摘为评价布里斯托大学开展的"积极生活五年级"规划(active for life year 5,AFLY5)能否在儿童中有效增加运动、减少静坐、提高蔬果摄入,抽取英格兰西南部60所小学四年级(8-9岁)学生为研究对象,在进入五年级时开展干预。这一干预活动包括教师培训、规定课程和亲子家庭规划,结局指标包括加速度计评价每日中等至高强度体力活和静坐时间、自我报告每日蔬果摄入。 | KIPPING RR HOWE LD JAGO R 孙莹 陶芳标 | 2014 | 中国学校卫生2014,35,11: | 6 |
| 10 | 全髋关节置换中髋臼假体位置对磨损的影响显示文摘髋臼杯倾斜角对全髋关节置换非常重要。研究显示,髋臼杯的倾斜角应≤45°,否则会加剧磨损。 | Wan Z Boutary M Dorr LD | 2009 | 中华骨科杂志2009,29,3: | 4 |
| 11 | Neuroprotective effects of daidzein on focal cerebral ischemia injury in rats显示文摘Daidzein, a plant extract, has antioxidant activity. It is hypothesized, in this study, that daidzein exhibits neuroprotective effects on cerebral ischemia. Rat models of middle cerebral artery occlusion were intraperitoneally administered daidzein. Biochemical and immunohistochemical tests showed that superoxide dismutase and nuclear respiratory factor 1 expression levels in the brain tissue decreased after ischemia and they increased obviously after daidzein administration; malondialdehyde level and apoptosis-related cysteine peptidase caspase-3 and caspase-9 immunoreactivity in the brain tissue increased after ischemia and they decreased obviously after daidzein administration. Hematoxylin-eosin staining and luxol fast blue staining results showed that intraperitoneal administration of daidzein markedly alleviated neuronal damage in the ischemic brain tissue. These findings suggest that daidzein exhibits neuroprotective effects on ischemic brain tissue by decreasing oxygen free radical production, which validates the aforementioned hypothesis. | Adem Bozkurt Aras Mustafa Guven Tar?k Akman Adile Ozkan Halil Murat Sen Ugur Duz Y?ld?ray Kalkan Coskun Silan Murat Cosar | 2015 | Neural Regeneration Research2015,10,1: | 4 |
| 12 | Outcome of the efficacy of Chinese herbal medicine for functional constipation:A systematic review and meta-analysis显示文摘BACKGROUND Functional constipation(FC)is a common and chronic gastrointestinal disease and its treatment remains challenging.AIM To evaluate the efficacy and safety of Chinese herbal medicine(CHM)on efficacy rate,global symptoms,bowel movements and the Bristol Stool Scale score in patients with FC by summarizing current available randomized controlled trials(RCTs).METHODS RCTs with CHM to treat FC were identified by a systematic search of six databases from inception to October 20,2020.Two independent reviewers assessed the quality of the included articles and extracted data.Meta-analyses were performed to odds ratio(OR),mean differences(MD)and 95%confidence interval(CI)using random-effects models.Subgroup analyses and sensitivity analyses were used to explore and interpret the sources of heterogeneity.The funnel plot,Begg’s test and Egger’s test were used to detect publication bias.RESULTS Ninety-seven studies involving 8693 patients were included in this work.CHM was significantly associated with a higher efficacy rate(OR:3.62,95%CI:3.19-4.11,P<0.00001)less severe global symptoms(OR:4.03,95%CI:3.49-4.65,P<0.00001)compared with control treatment,with the low heterogeneity between studies(I2=0%,P=0.76).CHM was also associated with more frequent bowel movements(MD 0.83,95%CI:0.67-0.98,P<0.00001),a lower score on the Bristol Stool Scale(OR:1.63,95%CI:1.15-2.32,P<0.006),and a not significant recurrence rate(OR:0.47,95%CI:0.22-0.99,P=0.05).No serious adverse effects of CHM were reported.CONCLUSION In this meta-analysis,we found that CHM may have potential benefits in increasing the number of bowel movements,improving stool characteristics and alleviating global symptoms in FC patients.However,a firm conclusion could not be reached because of the poor quality of the included trials.Further trials with higher quality are required. | Zipan Lyu Yibo Fan Yang Bai Tao Liu Linda LD Zhong Hui-Feng Liang | 2022 | World Journal of Clinical Cases2022,10,15: | 4 |
| 13 | Flexible organic light-emitting diodes with poly-3,4-ethylene-dioxythiophene as transparent anode显示文摘The flexible oragnic light-emitting diodes (OLEDs) fabricated on poly -3,4-ethylenedioxythiophene/poly -styrenesulfonate(PEDOT/PSS) coated substrates were demonstrated. How the fabricating processes and the device structure will affect the device performance was studied and the atomic force microscopy was employed to analyze the mophorlogy of the conducting polymer anode. Under optimized conditions, flexible OLEDs with PEDOT anode showed the brightness up to 2760 cd/m2 and maximum external quantum efficiency of 1.4%. These data are comparable to those of conventional flexible OLEDs with ITO anode. | Qiu, Y Duan, L Wang, LD | 2002 | Chinese Science Bulletin2002,47,23: | 4 |
| 14 | Intussusception in adults: an unusual and challenging condition for surgeons显示文摘 | Nazif Erkan Mehmet Hac?yanl? Mehmet Y?ld?r?m Hasan Sayhan Enver Vardar Alper F?rat Polat | 2005 | International Journal of Colorectal Disease2005,,5: | 3 |
| 15 | Intestinal mucosal MMP-1 – a prognostic factor in colon cancer显示文摘 | Marcus Langenski?ld Marie-Lois Ivarsson Lena Holmdahl Peter Falk Christina K?bj?rn-Gustafsson Eva Angenete | 2013 | Scandinavian Journal of Gastroenterology2013,,5: | 3 |
| 16 | Lamivudine resistance mutations in patients infected with hepatitis B virus genotype D显示文摘AIM: To determine the distribution of viral genotypes for primary or acquired lamivudine resistance. METHODS: A total of 283 patients with chronic hepatitis B virus (HBV) infection (245 patients with chronic hepatitis B and 38 inactive hepatitis B surface antigen carriers) were included in the study. The HBV geno-type was determined by using quantitative real-time polymerase chain reaction and sequence analysis, and tyrosine-methionine-aspartate-aspartate (YMDD) motif mutations were determined using the reverse transcriptase hybridization method. RESULTS: Lamivudine resistance was determined in a total of 25 (10.7%) chronic hepatitis B patients. Eight subjects (4%) had primary resistance to lamivudine, and 17 (53.1%) had secondary resistance to lamivudine. Genotype D, which was isolated from 267 of the patients with chronic HBV infection, was the dominant genotype in Turkey. CONCLUSION: Identification of YMDD motif mutations should have a positive impact on the selection of proper antiviral medication for patients, even for those who are nucleoside nave. | Orhan Yιldιz Bilgehan Aygen Nese Demirtürk Tuna Demirdal Dilara Inan Taner Yιldιrmak Arzu Kantürk Ediz Tütüncü Hepatitis B Study Group | 2011 | World Journal of Gastroenterology2011,17,45: | 3 |
| 17 | 心电图左心室肥厚电压标准与心血管病死亡率的关系显示文摘目前已提出多种使用心电图来诊断左心室肥厚的方法。它们识别病理性肥厚的灵敏度有限,至少部分是由于它们不能区分病理性和生理性肥厚。为此,Ha等使用心血管病死亡作为病理性肥厚的替代指标,比较主要的心电图左心室肥厚标准的预测能力。 | 刘莉 叶鹏 Ha LD Elbadawi A Froelicher VF | 2017 | 中华高血压杂志2017,25,12: | 3 |
| 18 | Salvage gamma knife stereotactic radiosurgery followed by bevacizumab for recurrent glioblastoma multiforme: a case-control study显示文摘We evaluated the efficacy and safety of gamma knife stereotactic radiosurgery(GKSR)followed by bevacizumab combined withchemotherapy in 11 patients with recurrent glioblastoma multiforme who experienced tumor progression despite aggressive | Park KJ Kano H Iyer A Liu X Niranjan A Flickinger JC Lieberman FS Lunsford LD Kondziolka D | 2012 | 中国神经肿瘤杂志2012,10,4: | 3 |
| 19 | Whether Syndrome Differentiation Affects Treatment Result:Study Protocol of MaZiRenWan(麻子仁丸)for Functional Constipation in A Randomized Controlled Trial显示文摘Background: Syndrome is one of the most important concepts in Chinese medicine(CM) theory. However, it was not well accounted in most of randomized controlled trials(RCTs). Objective: To determine whether CM syndrome differentiation affects the treatment results, functional constipation(FC) was selected as a target disease, and MaZiRenWan(麻子仁丸, MZRW), a classic CM formula commonly used for constipation with excessive heat syndrome, was selected for study. Methods: It is an 18-week prospective double-blinded, doubledummy RCT, including 2-week run-in, 8-week treatment and 8-week post treatment follow-up. A total of 120 FC patients diagnosed as excessive heat syndrome will be recruited from the First Teaching Hospital of Tianjin University of Traditional Chinese Medicine and the Baokang Affiliated Hospital of Tianjin University of Traditional Chinese Medicine. Patients will be randomly allocated into fixed MZRW(f_MZRW) granule group, modified MZRW(m_MZRW) granule group or bisacodyl group. For m_MZRW group, no more than two herbal granules can be added according to the syndrome differentiation for individual participants. The primary end point is the mean of complete spontaneous bowel movements(CSBMs) per week during the treatment period. Secondary end points include mean of CSBMs per week during follow-up, stool form, global symptom improvement, constipation and constipation-related symptoms assessment, CM syndrome change, and reported adverse events. Discussion: This trial is designed to evaluate the effectiveness of these three interventions for FC patients with the CM syndrome of excessive heat, and to determine the change of CM syndrome and the progress of disease during the treatment course. The results are important to explore whether syndrome differentiation is important for the therapeutic effect of a formula on a disease. | CHENG Chung-wah ZHANG Li ZHAO Chen ZHONG Linda LD SHI Li-jie DAI Liang ZHENG Rui CHEN Jing LI Ge ZHAI Jing-bo KUN Wai LU Ai-ping SHANG Hong-cai BIAN Zhao-xiang | 2019 | Chinese Journal of Integrative Medicine2019,25,3: | 3 |
| 20 | 成年小鼠中枢神经系统损伤后TT-301可抑制小胶质细胞活化及改善其预后(英文)显示文摘BACKGROUND Microglial inhibition may reduce secondary tissue injury and improve functional outcome following acute brain injury.Utilizing clinically relevant murine models of traumatic brain injury and intracerebral hemorrhage,neuroinflammatory responses and functional | James ML Cantillana V Kernagis DN Dawson HN Klaman LD Laskowitz DT | 2012 | 中华神经外科疾病研究杂志2012,11,2: | 3 |