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| 1 | Nutritional and health benefits of semi-elemental diets: A comprehensive summary of the literature显示文摘AIM:To critically review and summarize the literature on nutritional and health outcomes of semi-elemental formulations on various nutritionally vulnerable patient populations who are unable to achieve adequate nutrition from standard oral diets.METHODS:We conducted a comprehensive literature search of Pubmed and Embase databases.We manually screened articles that examined nutritional and health outcomes(e.g.,growth,disease activity,gastrointestinal impairment,mortality,and economic impact)among various patient groups receiving semi-elemental diets.This review focused on full-text articles of randomized controlled clinical trials and other intervention studies,but pertinent abstracts and case studies were also included.Results pertaining primarily to tolerance,digestion,and absorption were summarized for each patient population in this systematic review.RESULTS:Results pertaining primarily to tolerance,digestion,and absorption were summarized for each patient population.The efficacy of semi-elemental whey hydrolyzed protein(WHP)diet have been reported in various nutritionally high risk patient populations including-Crohn’s disease,short bowel syndrome,acute and chronic pancreatitis,cerebral palsy,cystic fibrosis,cerebrovascular accidents,human immunodeficiency virus,critically ill,and geriatrics.Collectively,the evidence from the medical literature indicates that feeding with a semi-elemental diet performs as well or better than parenteral or amino acid based diets in terms of toler-ance,digestion,and nutrient assimilation measures across various disease conditions.CONCLUSION:Based on this comprehensive review of the literature,patient populations who have difficulty digesting or absorbing standard diets may be able to achieve improved health and nutritional outcomes through the use of semi-elemental WHP diets. | Dominik D Alexander Lauren C Bylsma Laura Elkayam Douglas L Nguyen | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，2： | 3 |
| 2 | 14-day triple, 5-day concomitant, and 10-day sequential therapies for Helicobacter pylori infection in seven Latin American sites: a randomised trial显示文摘 | E Robert Greenberg Garnet L Anderson Douglas R Morgan Javier Torres William D Chey Luis Eduardo Bravo Ricardo L Dominguez Catterina Ferreccio Rolando Herrero Eduardo C Lazcano-Ponce María Mercedes Meza-Montenegro Rodolfo Pe?a Edgar M Pe?a Eduardo Salazar- | 2011 | The Lancet2011，，9790： | 2 |
| 3 | Predictors of progression in Barrett’s esophagus II: baseline 17p (p53) loss of heterozygosity identifies a patient subset at increased risk for neoplastic progression显示文摘 | Brian J Reid Laura J Prevo Patricia C Galipeau Carissa A Sanchez Gary Longton Douglas S Levine Patricia L Blount Peter S Rabinovitch | 2001 | The American Journal of Gastroenterology2001，，10： | 2 |
| 4 | Difference in dietary intake between women with polycystic ovary syndrome and healthy controls 显示文摘 | Douglas C C Norris L E Oster R A | 2006 | Fertil Steril2006，86，2： | 1 |
| 5 | Wheat straw composition and placement effects on decomposition in agriculture of the Pacific Northwest显示文摘 | DOUGLAS C L | 1980 | Soil Science Am1980，44，： | 1 |
| 6 | Guidelines for Conscious Sedation and Monitoring During Gastrointestinal Endoscopy显示文摘 | J.Patrick Waring Todd H Baron William K Hirota Jay L Goldstein Brian C Jacobson Jonathan A Leighton J.Shawn Mallery Douglas O Faigel | 2003 | Gastrointestinal Endoscopy2003，，3： | 1 |
| 7 | Fertility sparing therapy for ovarian cancer has inherent risks and benefits显示文摘 | Douglas N C Fan L Pothuri B | 2005 | Arch Gynecol Obstet2005，272，4： | 1 |
| 8 | Crop rotation and residue management effects on soil carbon and microbial dynamics 显示文摘 | Collins H P Rasmussen P E Douglas C L | 1992 | Soil Science Society of America Journal1992，56，3： | 1 |
| 9 | Selective ETA receptor antagonism with BQ-123 is insufficient to inhibit angioplasty induced neointima formation in the rat 显示文摘 | Douglas S A Vickery-Clark L M Louden C | 1995 | Cardiovasc Res1995，29，5： | 1 |
| 10 | Resultsfrom the 1995 national college health risk behavior survey显示文摘 | Douglas K A Collins J L Warren C | 1997 | J Am College Health1997，46，2： | 1 |
| 11 | Cleaning up clostridium difficile infection显示文摘 | Matthew R T Scott C L Douglas R | 2002 | Mayo Clin Proc2002，76，9： | 1 |
| 12 | The design and performance of a real-time CORBA scheduling service显示文摘 | Christopher D G David L L Douglas C S | 2001 | Real-Time Systems2001，20，2： | 1 |
| 13 | Nitrogen and Phosphorus in Surface runoff and sediment from a Wheat - pea rotation in Northeastern Oregon 显示文摘 | Douglas C L King K A Zuzel J F | 1998 | Journal of Environment Quality1998，27，5： | 1 |
| 14 | A new test instrument and procedure for evaluation of fabrics containing phase-change material显示文摘 | Douglas C H Tifani L A | 2002 | ASHRAS45092002，，1： | 1 |
| 15 | Nitric oxide mediates mitogenic effect of VEGF on coronary venular endothelium 显示文摘 | MORBIDELLI L CHANG C H DOUGLAS J G | 1996 | Am J1996，270，： | 1 |
| 16 | Tacrolimus for the treatment of fistulas in patients with crohn’s disease: a randomized, placebo-controlled trial显示文摘 | William J Sandborn Daniel H Present Kim L Isaacs Douglas C Wolf Eugene Greenberg Stephen B Hanauer Brian G Feagan Lloyd Mayer Therese Johnson Joseph Galanko Christopher Martin Robert S Sandler | 2003 | Gastroenterology2003，，2： | 1 |
| 17 | Does increased nerve length within the treatment volume improve trigeminal neuralgia radiosurgery? a prospective double-blind, randomized study显示文摘 | John C Flickinger Bruce E Pollock Douglas Kondziolka Loi K Phuong Robert L Foote Scott L Stafford L.Dade Lunsford | 2001 | International Journal of Radiation Oncology Biology Physics2001，，2： | 1 |
| 18 | Significance of genetic information in risk assessment and individual classification using silicosis as a case model 显示文摘 | ERIN M C DOUGLAS P L BERRAN Y | 2002 | Ann Occup Hyg2002，46，4： | 1 |
| 19 | The rapid estimation of the layer charges of 2∶1 expanding clays from a single alkylammonium ion expansion显示文摘 | Oils A C Malla P B Douglas L A | 1990 | Clay Minerals1990，25，： | 1 |
| 20 | What Factors Predict the Response of Larger Brain Metastases to Radiosurgery?显示文摘 | Huai-che Yang Hideyuki Kano L Dade Lunsford Ajay Niranjan John C Flickinger Douglas Kondziolka | 2011 | Neurosurgery2011，，3： | 1 |
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