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| 1 | 骨桥蛋白通过激活NF-κB通路促进根尖周炎的骨质破坏显示文摘Dong M,Yu X,Chen W,et a1.Osteopontinpromotes bone destruction in periapieal periodontitisby activating the NF—κB pathway.Cell PhysiolBiochem,2018,49:3.目的:根尖周炎由细菌感染引起.导致牙槽骨破坏和牙脱落。骨桥蛋白(OPN)是一种磷酸化糖蛋白.参与骨代谢。方法:对33例慢性根尖周炎患者和10例因正畸切除健康牙体组织(对照)的患者进行研究.建立小鼠根尖周炎动物模型进行体内实验.分析OPN与根尖周炎中骨质破坏的关系。在体外培养成骨细胞和破骨细胞并用脂多糖处理。NF—κB的抑制剂用于预处理转染的细胞。结果:OPN增加破骨细胞增殖和分化,但减少成骨细胞增殖和分化。OPN在根尖周炎期间激活NF—KB通路.加速P65从细胞质向细胞核的转移和磷酸化。结论:OPN在根尖周炎的发展过程中发挥重要作用.并且在根尖周炎期间骨关节代谢中起双重作用.将破骨细胞与成骨细胞联系起来。其潜在的机制可能与NF—κB途径有关。 | Dong M Yu X Chen W 赵泽亮 | 2018 | 中国口腔颌面外科杂志2018，16，6： | 14 |
| 2 | 不同丘脑神经环路分别调控组织损伤和抑郁样状态引起的机械痛敏显示文摘丘脑是疼痛传导通路中重要的脑区之一,疼痛的上行传导与下行调控通路中均有丘脑参与调节。组织损伤和负面情绪(如抑郁)都能引起痛觉敏化,但是否由不同的丘脑环路调控尚不清楚。目的:探讨丘脑调控组织损伤引起的痛敏和抑郁情绪产生痛敏的机制。方法:(1)动物模型:注射完全弗氏佐剂(CFA)建立小鼠慢性炎症痛模型或通过保留性神经损伤(SNI)建立小鼠神经病理性疼痛模型;采用慢性束缚应激(CRS)或慢性不可预测应激(CUS)诱导小鼠出现抑郁样行为的同时引起痛敏;(2)行为学实验:采用von Frey hair纤维丝检测机械痛敏;采用社交行为、悬尾实验和强迫游泳检测抑郁样情绪。 | Zhu X Tang HD Dong WY 王佳昕(译) 刘风雨(校) | 2021 | 中国疼痛医学杂志2021，27，7： | 7 |
| 3 | High-dose methylprednisolone can induce remissions in patients with fludarabine- refractory chronic lymphocytic leukaemia显示文摘 | Xu, W Miao, KR Hong, M Zhu, DX Fang, C Dong, HJ Wang, DM Cao, X Li, JY | 2010 | 南京医科大学学报(自然科学版)2010，30，11： | 5 |
| 4 | Diurnal variation of ozone flux over corn field in Northwestern Shandong Plain of China显示文摘High concentration ground-level ozone(O3)has adverse effects on plant growth and photosynthesis.Compared to the O3concentration-based index,the O3flux-based(especially stomatal O3uptake)index has been considered the better criterion for assessing the impact of ozone on vegetation and ecosystems.This paper reports on a study of O3flux using the eddy covariance technique over a corn field in the Northwestern Shandong Plain of China.Diurnal variation of atmospheric O3concentration,deposition velocity and flux,and their relationships to environmental factors are analyzed.The results show that:(1)During the observation period(9 August–28 September,2011),there was a strong diurnal variation of O3concentration,with low(16.5 nL L?1)and high(60.1 nL L?1)O3mean concentrations observed around 6:30 and 16:00,respectively.Mean O3concentrations during daytime(6:00–18:00)and nighttime(18:00–6:00)were 39.8±23.1 and 20.7±14.1 nL L?1(mean±std),respectively.The maximum observed concentration was 97.5 nL L?1.The concentration was mainly affected by solar radiation and air temperature.(2)Whether daytime or nighttime,ground-level O3flux is always downward.The diurnal course of mean deposition velocity was divided into 4 phases:a low and stable process during nighttime,fast increasing in early morning,relatively large and steady changes around noon,and quickly decreasing in later afternoon.Daytime and nighttime mean deposition velocities were 0.29 and 0.09 cm s?1,respectively.The maximum deposition velocity was 0.81 cm s?1.The magnitude of deposition velocity was influenced by the corn growth period,and its diurnal variation was significantly correlated with global radiation and relative humidity.(3)O3flux was affected by variations of both O3concentration and deposition velocity,with mean O3fluxes-317.7 and?70.2 ng m?2s?1during daytime and nighttime,respectively.There was strong correlation between O3flux and CO2flux or latent heat flux.By comparing the deposition velocities of daytime and nighttime,we infer that stomatal uptake was probably the main sink of ground-level O3. | ZHU ZhiLin SUN XiaoMin DONG YunShe ZHAO FengHua Franz X MEIXNER | 2014 | Science China Earth Sciences2014，57，3： | 5 |
| 5 | 查看详情显示文摘 | W C Huang H Y Tam P K A Wai X Y Dong H Ming J P Xie | | 中国物理快报(英文版)0，，： | 4 |
| 6 | 改性十六烷基甜菜碱表面活性剂在个人护理品中的应用显示文摘开发了一种温和的源自天然原料的表面活性剂。它能够与各种水溶助长性表面活性剂复配并有效地提高护发和护肤产品的温和性、黏度及发泡性。 | Susan X M Dong Branko Sajic Anatoly Dameshek 谢文炳 | 2012 | 日用化学品科学2012，35，2： | 3 |
| 7 | 急性缺血性卒中低剂量组织型纤溶酶原激活物静脉溶栓:备选还是新标准?显示文摘组织型纤溶酶原激活物(tissue plasminogen activator,t PA)静脉溶栓是目前唯一被证实对急性缺血性卒中(acute ischemic stroke,AIS)有效的内科治疗手段,但tPA最佳剂量问题一直存在争议,国际脑血管病指南推荐采用标准剂量(0.9 mg/kg)治疗。由于种族差异等因素,有人认为亚洲AIS患者选择低剂量tPA可能更为合适。 | dong y cao w cheng x 张玉生 | 2018 | 中国卒中杂志2018，13，2： | 2 |
| 8 | Cancer mortality among silicostics in Chinas metallurgical industry 显示文摘 | Wang Z Dong D Liang X | 1996 | Inter J Epidemiol1996，25，5： | 2 |
| 9 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 2 |
| 10 | In vivo chondrogenesis of adult bone-marrow-derived autologous mesenchymal stem cells显示文摘 | Chen J Wang C Lu S Wu J Guo X Duan C Dong L Song Y Zhang J Jing D Wu L Ding J Li D | 2006 | 中国生物学文摘2006，20，5： | 2 |
| 11 | Impaired cardiac contractile function in ventricular myocytes from leptin-deficient ob/ob obese mice显示文摘 | Dong F Zhang X Yang X | 2006 | J Endocrinol2006，188，1： | 1 |
| 12 | Electronic structure and optical properties of the Co-doped anatase TiO2 studied from first principles 显示文摘 | Weng H M Yang X P Dong J M | 2004 | Phys Rev2004，69，12： | 1 |
| 13 | Information technology in supply chains: The value of IT-enabled resources under competition 显示文摘 | Dong S Xu S X Zhu K X | 2009 | Information Systems Research2009，20，1： | 1 |
| 14 | Molecular sensing with the tunnel junction of an Au nanogap in solution 显示文摘 | DONG X D XIA Y ZHU G Y | 2007 | Nanotechnology2007，18，39： | 1 |
| 15 | Study of polystyrene and acrylomtrile-styrene copolymer as special beta-nucleating agents to induce the crystallization of isotactic polypropylene 显示文摘 | SU Z Q DONG M GUO Z X | 2007 | Macromolecules2007，40，： | 1 |
| 16 | Costimulation,coinhibition and cancer显示文摘 | Inman B A Frigola X Dong H | 2007 | Curr Cancer Drug Targets2007，7，1： | 1 |
| 17 | Studies on CdSalen immobilized onto N-(4-pyridylmethylidene) chitosan显示文摘 | Hu D Cui Y L Dong X L | 2001 | Reactive and Functional Polymers2001，48，13： | 1 |
| 18 | Seed-mediated synthesis of branched gold nanoparticles with the assistance of citrate and their surface-enhanced Raman scattering properties显示文摘 | Zou X Q Ying E B Dong S J | 2006 | Nanotechnol2006，17，： | 1 |
| 19 | Effects of platelet-activating factor,tumor necrosis factor,and interleukin-1α on the expression of apolipoprotein M in HepG2 cells显示文摘 | Xu N Zhang XY Dong X | 2002 | Biochem Biophys Res Commun2002，292，4： | 1 |
| 20 | Mesenchymal stem cell-based repair of articular cartilage with polyglycolic acid-hydroxyapatite biphasic scaffold显示文摘 | Zhou X Z Leung V Y Dong Q R | 2008 | Int J Artif Organs2008，31，6： | 1 |
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