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| 1 | In-vitra interac tions of itraconazole with flucytosine against clinical isolates of Cryptococcus neoformans显示文摘 | Domenico G Francesca C | 1999 | J Antimicrob Chemother1999，44，1： | 1 |
| 2 | Heme oxygenase-1 expression in the left atrial myocardium of patients with chronic atrial fibrillation related to mitral valve disease: its regional relationship with structural remodeling 显示文摘 | DOMENICO C M D SERGIO C M D ROBERTA M B | 2008 | Human Pathology2008，39，： | 1 |
| 3 | Erlotinib inhibits progression to dysplasia in a colitis-associated colon cancer model显示文摘AIM:To investigate the role of epidermal growth factor receptor(EGFR) in colitis-associated dysplasia using the EGFR tyrosine kinase inhibitor erlotinib.METHODS:Sprague-Dawley rats received trinitrobenzene sulfonic acid(TNBS;30 mg in 50% ethanol,ic),followed 6 wk later by reactivation with TNBS(5 mg/kg,iv) for 3 d.To induce colitis-associated dysplasia,rats then received TNBS(iv) twice a week for 10 wk.One group received erlotinib(10 mg/kg,ip) for 1 wk before the start of the reactivation of the colitis and 2 wk after(21 d);the rest received the vehicle.After rats were euthanized,the colons were removed and analyzed for damage and expression of the EGFR downstream effectors Erk1/2 and c-Myc.RESULTS:Ninety percent of the vehicle-treated animals had dysplasia in any region of the colon.Erlotinib-treated animals had a significant decrease in the incidence of dysplasia compared to vehicle-treated animals in all regions of the colon(50.00% ± 11.47% vs 90.00% ± 10.00% in proximal,P < 0.05;15.00% ± 8.19% vs 50.00% ± 16.67% in mid,P < 0.05;and 20.00% ± 9.17% vs 70.00% ± 15.28% in distal,P < 0.01).Erlotinib-treated animals also had reduced cell proliferation,reduced active Erk1/2,and reduced c-Myc in colon epithelium compared with the vehicle-treated animals.In vitro,erlotinib treatment was shown to markedly decrease c-Myc and pErk1/2 levels in rat epithelial cells.Proliferation of rat epithelial cells was stimulated by epidermal growth factor and inhibited by erlotinib(P < 0.05).CONCLUSION:Erlotinib can decrease the development of colitis-associated dysplasia,suggesting a potential therapeutic use for erlotinib in patients with long-standing colitis. | Beatriz Pagán Angel A Isidro Myrella L Cruz Domenico Coppola Caroline B Appleyard | 2011 | World Journal of Gastroenterology2011，17，44： | 1 |
| 4 | Second trimester neutrophil gelatinase associated lipoealin as a potential prediagnostic marker of preeclampsia 显示文摘 | Rosario D Giovanni B Domenico G | 2008 | Acta Obstet Gynecol Scand2008，87，： | 1 |
| 5 | Growth of AlN piezoelectric film on diamond for high-frequency surface acoustic wave devices显示文摘 | MASSIMILIANO B DOMENICO C | 2001 | IEEE Trans UltrasonFerroelectr2001，52，6： | 1 |
| 6 | Three-Dimensional Electroanatomical Voltage Mapping and Histologic Evaluation of Myocardial Substrate in Right Ventricular Outflow Tract Tachycardia 显示文摘 | Domenico C Cristina B Loira L | 2008 | J Am Coll Cardiol2008，51，： | 1 |
| 7 | Development of Small Molecule Inhibitors and Probes of Human SUMO Deconjugating Proteases显示文摘 | Victoria E. Albrow Elizabeth L. Ponder Domenico Fasci Miklós Békés Edgar Deu Guy S. Salvesen Matthew Bogyo | 2011 | Chemistry & Biology2011，，6： | 1 |
| 8 | Sudden cardiac death in young people with apparently normal heart 显示文摘 | Domenico C Cristina B Gaetano T | 2001 | Cardiovasc Res2001，50，2： | 1 |
| 9 | Deoxyribonucleic acid (DNA) biosensors for environmental risk assessment and drug studies显示文摘 | GRAZIANA B DOMENICO O ELENA S | 2006 | Analyfica Chimica Acta2006，57，： | 1 |
| 10 | Plasma and serum levels of D dimmer andtheir correlation with other haemostatic parameters in pregnancy显示文摘 | Domenico P Bandinelli B | 2002 | Thromb Res2002，105，： | 1 |
| 11 | Three-dimensional electro- anatomical voltage mapping and histologie evaluation of myocardial substrate in fight ventricular outflow tract tachyeardia显示文摘 | Domenico C Cristina B Loira L | 2008 | J Am Coll Cardiol2008，51，7： | 1 |
| 12 | Grids and Grid Technologies for Wide-Area Distributed Computing 显示文摘 | MARK B RAJKUMAR B DOMENICO L | 2002 | International Journal of Software: Practice and Experience (SPE)2002，32，15： | 1 |
| 13 | Effect of methylguanidine in a model of septic shock induced by LPS显示文摘 | Marzocco S Di Paola R Ribecco MT Sorrentino R Domenico B Genesio M | 2004 | Free Radic Res2004，38，： | 1 |
| 14 | Thermo-struc tural behaviour of an UHTC made nose cap of a reentry vehicle显示文摘 | Rosario B Aniello R Domenico T | | 0，，03： | 1 |
| 15 | Surface complexation modeling of phosphate adsorption by water treatment residual显示文摘 | Michael A B Domenico G Cristian P | 1998 | Journal of Environmental Quality1998，27，： | 1 |
| 16 | Growth of AIN piezoelectric film on diamond for high-frequency surface acoustic wave devices 显示文摘 | Massimiliano B Domenico C Fabio D P | 2005 | IEEE Trans UFFC2005，52，10： | 1 |
| 17 | Prevalence of body iron excess in the metabolic syndrome显示文摘 | Claudia B Ilaria T Domenico G | 2005 | Diabetes Care2005，28，2： | 1 |
| 18 | Nonfilamentous Candida albicans mutants are avirulent 显示文摘 | Lo H Kohler J R Di Domenico B | 1997 | Cell1997，90，5： | 1 |
| 19 | Comparison of two current modulation strategies for matrix converters under unbalanced input voltage conditions 显示文摘 | FREDE B DOMENICO C CHRISTIAN K | 2002 | IEEE Transactions on Industrial Electronics2002，49，2： | 1 |
| 20 | 50 W CW visible laser source at 589 nm obtained via frequency doubling of three coherently combined narrow-band Raman fiber amplifiers显示文摘 | Luke R T Yan Feng Domenico B C | 2010 | Opt Express2010，18，8： | 1 |
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