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| 1 | Development of an Arabic version of the National Eye Institute Visual Function Questionnaire as a tool to study eye diseases patients in Egypt显示文摘AIM:To develop and test an Arabic version of the National Eye Institute Visual Function Questionnaire-25(NEI-VFQ-25).METHODS:NEI-VFQ-25 was translated into Arabic according to WHO translation guidelines. We enrolled adult consenting patients with bilateral chronic eye diseases who presented to 14 hospitals across Egypt from October to December 2012, and documented their clinical findings. Psychometric properties were then tested using STATA.RESULTS:We recruited 379 patients, whose mean age was(54.5±15)y. Of 46.2% were males, 227 had cataract,31 had glaucoma, 23 had retinal detachment, 37 had diabetic retinopathy, and 61 had miscellaneous visual defects. Non-response rate and the floor and ceiling numbers of the Arabic version(ARB-VFQ-25) were calculated. Internal consistency was high in all subscales(except general health), with Cronbach-α ranging from0.702-0.911. Test-retest reliability was high(intraclass correlation coefficient 0.79).CONCLUSION:RB-VFQ-25 isareliableandvalidtool for assessing visual functions of Arabic speaking patients. However, some questions had high non-response rates and should be substituted by available alternatives. Our results support the importance of including self-reported visual functions as part of routine ophthalmologic examination. | Nizar Saleh Abdelfattah Mohamed Amgad Ahmed A Salama Marina E Israel Ghada A Elhawary Ahmed E Radwan Mohamed M Elgayar Tamer M EL Nakhal Islam T Elkhateb Heba A Hashem Doha K Embaby Amira A Elabd Reem K Elwy Magdi S Yacoub Hamdy Salem Mohamed Abdel-Baqy Ahmad Kassem | 2014 | International Journal of Ophthalmology(English edition)2014，7，5： | 8 |
| 2 | Effect of mucin production on survival in colorectal cancer:A case-control study显示文摘AIM: To investigate the impact of mucin production on prognosis in colorectal cancer, in terms of overall survival (OS) and time to disease progression (TTP) in patients with mucinous compared to those with non-mucinous colorectal cancer (NMCRC), matched for age, gender, and tumor stage.METHODS: Thirty five patients with mucinous colorectal cancer (MCRC) were matched for age, gender, and tumor stage with 35 controls having NMCRC. OS and TTP were compared among 4 groups divided according to mucin content: group A (50%-75% mucin), group B (75%-100% mucin), group C or controls (< 50% mucin). Group D consisted of all patients with tumors having < 75% mucin (controls and groups A together).RESULTS: Median survival in MCRC and NMCRC groups was 46.2 and 112.9 mo, respectively (P = 0.26). OS in groups A and B was 70.1 and 32.8 mo (P = 0.46), and in groups B and D was 32.8 and 70.1 mo, respectively (P = 0.143). TTP in MCRC and NMCRC was 50.17 and 44.77 mo, respectively (P = 0.795). TTP in groups A, B, and D was 70.1, 24.8, and 65.5 mo, respectively. Twenty-eight percent of patients with MCRC had poorly differentiated adenocarcinoma versus 8.6% in NMCRC patients (P = 0.028).CONCLUSION: MCRC is associated with a non-significant decrease in median survival and TTP, particularlywhen mucin content is > 75% of tumor volume. However, it tends to be more poorly differentiated. A larger study matching for stage and grade is needed. | Mirna H Farhat Kassem A Barada Ayman N Tawil Doha M Itani Hassan A Hatoum Ali I Shamseddine | 2008 | World Journal of Gastroenterology2008，14，45： | 6 |
| 3 | prevention of renal dysfunction by nutraceuticals prepared from oil rich plant foods显示文摘Objective:To investigate the protective effect of extracts prepared from avocado,walnut,flaxseed and Eruca sativa seeds in a rat model of kidney dysfunction induced by intraperitoneal cisplatin.Methods:Ethanol and petroleum ether extracts mixture was prepared from each plant.Six groups of rats were conducted:control healthy,cisplatin group and four test groups where rats were given daily oral dose of each extract mixture before cisplatin injection.Different biochemical and cytogenetic parameters and kidney histopathology were determined.Acute toxicity was tested for the nutraceuticals.Total phenolic contents,faity acids(FA) and unsaponifiable matter were assessed in the extracts.Results:Walnut ethanol extract showed the highest content of total phenolic.FA analysis revealed that all the studied plants were rich in unsaturated FA.Gas-liquid chromatographic investigation of the unsaponifiable matter showed the presence of campeslerol.stigmaslerol and β—sitosterol in all the studied plants.Cisplatin treatment induced significant increase in plasma urea,creatinine and malondialdehyde along with significant reduction of plasma albumin,total protein,calalase and total antioxidant as well as reduction in creatinine clearance.Histopathological examination proved the induction of kidney dysfunction.Some sorts of chromosomal aberration and spermshape abnormalities were noticed after cisplatin treatment.Administration of extracts mixtures produced improvements in biochemical,histopathological and cytogenetic parameters.Conclusions:Administration of the studied nutraceuticals proved to possess protective role against cisplatin—induced nephrotoxicity,chromosomal aberration and abnormal sperms.All studied uutraceuticals showed complete safety. | Sahar Y.Al-Okbi Doha A.Mohamed Thanaa E.Hamed Reham SH.Esmail Souria M.Donya | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，4，8： | 5 |
| 4 | SOX9 in biliary atresia: New insight for fibrosis progression显示文摘Background:Liver fibrosis is a hallmark determinant of morbidity in biliary atresia(BA)even in successfully operated cases.Responsible factors for this rapid progression of fibrosis are not completely defined.Aberrant expression of the transcription factor SOX9 and hepatic progenitor cells(HPCs)proliferation have roles in fibrogenesis in cholestatic disorders.However,they were not investigated sufficiently in BA.We aimed to delineate the relation of SOX9 and HPCs to fibrosis and its progression in BA.Methods:Forty-eight patients with BA who underwent an initial diagnostic liver biopsy(LB)and consequent intraoperative LB were recruited and compared to 28 cases with non-BA cholestasis that had an LB in their diagnostic workup.Liver fibrosis,tissue SOX9 and HPC expressions were studied in both BA and non-BA-cholestasis cases.Liver fibrosis,SOX9,and HPCs’dynamic changes in BA cases were assessed.Relation of fibrosis and its progression to SOX9 and HPCs in BA was assessed.Results:SOX9 and HPCs in ductular reaction(DR)form were expressed in 100%of BA and their grades increased significantly in the second biopsy.The rapidly progressive fibrosis in BA,represented by fibrosis grade of the intraoperative LB,correlated significantly to SOX9-DR and HPC-DR at the diagnostic(r=0.420,P=0.003 and r=0.405,P=0.004,respectively)and the intraoperative(r=0.460,P=0.001 and r=0.467,P=0.001,respectively)biopsy.On the other hand,fibrosis,SOX9-DR,and HPC-DR were significantly lower in non-BA cases at a comparable age(P<0.001,P=0.006,and P=0.014,respectively).Conclusions:Fibrosis in BA is rapidly progressive within a short time and is significantly correlated to SOX9 and HPCs.Assessment of targeting SOX9 and HPCs on fibrosis progression is warranted. | Hanaa Ahmed El-Araby Magdy Anwar Saber Noha Mohamed Radwan Doha Maher Taie Nermin Mohamed Adawy Ahmad Mohamed Sira | 2021 | Hepatobiliary & Pancreatic Diseases International2021，20，2： | 3 |
| 5 | 显示文摘 | Doha S G Kimb E B Leeb B H | 2004 | Jour Magn Magn Mater2004，272，： | 1 |
| 6 | Charaeteristies and synthesis of Cu-Ni ferrite nanopowders by coprecipitation method with ultrasound irradiation 显示文摘 | Doha S G Kimb E B Lee B H | 2004 | Magnet Magnet Mater2004，，： | 1 |
| 7 | Polymorphism of the C-reactive protein (CRP) gene is related to senan CRP level and arterial pulse wave velocity in healthy elderly Japanese 显示文摘 | Morita A Nakayama T Doha N | 2006 | Hypertens lies2006，29，5： | 1 |
| 8 | The sodium/iodide symporter (NIS):Characterization,reg- ulation,and medical significance显示文摘 | Orsolya Doha N Antonio De La Vieja Viktoriya Paroder | 2007 | Endocrine Reviews2007，24，1： | 1 |
| 9 | Deposition rates on smooth surfaces and coagulation of aerosol particles inside a test chamber显示文摘 | HUSSEIN T HRUSKA A DOHA NYOSOV (A) P | | 0，，： | 1 |
| 10 | Ketorolac amide prodrugs for transdermal delivery: stability and in vitro rat skin permeation studies 显示文摘 | Kima BY Doha HI Leb TN | 2005 | Int J Pharm2005，293，4： | 1 |
| 11 | A Polymorphism in IL28B Distinguishes Exposed, Uninfected Individuals From Spontaneous Resolvers of HCV Infection显示文摘 | Susanne Knapp Usama Warshow K.M. Alexander Ho Doha Hegazy Ann–Margaret Little Andrew Fowell Graeme Alexander Mark Thursz Matthew Cramp Salim I. Khakoo | 2011 | Gastroenterology2011，，1： | 1 |
| 12 | Jacobi spectral Galerkin method for elliptic Neumann problems显示文摘 | DOHA E H BHRAWY A H ABD-ELHAMEED W M | 2009 | Numer Algor2009，50，： | 1 |
| 13 | Integrals of Bernstein polynomials:an application for the solution of high even-order differential equations 显示文摘 | Doha E H Bhrawy A H Saker M A | 2011 | Applied Mathematics Letters2011，，24： | 1 |
| 14 | Effects of cranberry juice consumption on vascular function in patients with coronary artery disease显示文摘 | DOHA M M HOLB M HAMBURG N M | 2011 | Am J Clin Nutr2011，93，： | 1 |
| 15 | Integrals of Bernstein polynomials: An application for the solution of high even-order differential equations显示文摘 | DOHA E H BHRAWY A H SAKER M A | 2011 | Appl Math Lett2011，24，4： | 1 |
| 16 | Integrals of Bernstein poly- nomials : an application for the solution of high even-order differential equations显示文摘 | DOHA E H BHRAWY A H SAKER M A | 2011 | Applied Mathematics Letters2011，24，4： | 1 |
| 17 | Susceptibility patterns and virulence genotypes of Helicobacter pylori affecting eradication therapy outcomes among Egyptian patients with gastroduodenal diseases显示文摘BACKGROUND Helicobacter pylori(H.pylori)is a significant human pathogen that is responsible for a variety of illnesses,including mucosa-associated lymphoid tissue lymphoma,gastric cancer,peptic ulcers,and gastritis.AIM To investigate the frequency of H.pylori infection and its resistance patterns among Egyptian patients and to determine the influence of H.pylori virulence genetic determinants on the eradication success of 14-d triple therapy regimen.METHODS H.pylori infections were investigated in 72 patients with gastroduodenal complications suggestive of H.pylori infection.The cagA and vacA genotypes of cultured strains were studied using polymerase chain reaction.The patients underwent 14 d of triple-therapy treatment.The treatment response was examined using histology and a rapid urease test 6 wk after therapy discontinuation.RESULTS The intention-to-treat eradication rate was 59.2%(95%CI:48.2%-70.3%).Rates of H.pylori resistance to clarithromycin,amoxicillin,and metronidazole were 52.8%,81.9%,and 100%,respectively.Successful eradication of H.pylori was more significantly associated with vacA s1-positive strains[adjusted odds ratio(aOR)=0.507,95%CI:0.175-0.822].A significant association was found between failed eradication rate and H.pylori strains resistant to clarithromycin(aOR=0.204,95%CI:-0.005 to 0.412)and amoxicillin(aOR=0.223,95%CI:0.026-0.537).CONCLUSION This study’s low H.pylori eradication rate following 14-d triple therapy is concerning and worrying.H.pylori pan-resistance to metronidazole followed by the high resistance to ciprofloxacin,amoxicillin,and clarithromycin in this research is challenging and of great concern. | Ahmed Morad Asaad Gasser El-Azab Eman Abdelsameea Osama Elbahr Ahmed Kamal Mohamed Abdel-Samiee Ahmed Abdelfattah Heba Abdallah Doha Maher Ahmed El-Refaie Samar Ebrahim Ghanem Shamshul Ansari Samah Mohammed Awad | 2023 | World Journal of Gastroenterology2023，29，19： | 1 |
| 18 | On the rate of convergence of the Legendre spectral collocation method for multidimensional nonlinear Volterra-Fredholm integral equations显示文摘While the approximate solutions of one-dimensional nonlinear Volterra-Fredholm integral equations with smooth kermels are now well understood,no systematic studies of the numerical solutions of their multi-dimensional counterparts exist.In this paper,we provide an efficient numerical approach for the multi-dimensional nonlinear Volterra-Fredholm integral equations based on the multi-variate Legendre-collocation approach.Spectral collocation methods for multi-dimensional nonlinear integral equations are known to cause major difficulties from a convergence analysis point of view.Consequently,rigorous error estimates are provided in the weighted Sobolev space showing the exponential decay of the numerical errors.The existence and uniqueness of the numerical solution are established.Numerical experiments are provided to support the theoretical convergence analysis.The results indicate that our spectral collocation method is more flexible with better accuracy than the existing ones. | Nermeen A Elkot Mahmoud A Zaky Eid H Doha Ibrahem G Ameen | 2021 | Communications in Theoretical Physics2021，73，2： | 0 |
| 19 | From appropriation to formal intervention:An analytical framework for understanding the appropriation process in residual spaces of Cairo显示文摘The paper addresses the issue of how residual spaces are intervened upon through formal and informal processes.It argues that a profound understanding for the dynamics of informal interventions,denoted by appropriation,could enhance the performance of their formal peers.Adopting a qualitative approach,the paper departs from Lefebvre's unitary theory of space and arrives at an analytical framework that helps to understand the appropriation processes in residual spaces.It,then,attempts to empirically challenge the applicability of this framework through analyzing a Cairene residual space that has undergone two cycles of intervention:a formal and informal one. | Doha Eissa Marwa Hassan Khalil Aly Gabr Ahmed Abdelghaffar | 2019 | Frontiers of Architectural Research2019，8，2： | 0 |
| 20 | Application of four machine-learning methods to predict short-horizon wind energy显示文摘Renewable energy has garnered attention due to the need for sustainable energy sources.Wind power has emerged as an alternative that has contributed to the transition towards cleaner energy.As the importance of wind energy grows,it can be crucial to provide forecasts that optimize its performance potential.Artificial intelligence(AI)methods have risen in prominence due to how well they can handle complicated systems while enhancing the accuracy of prediction.This study explored the area of AI to predict wind-energy production at a wind farm in Yalova,Turkey,using four different AI approaches:support vector machines(SVMs),decision trees,adaptive neuro-fuzzy inference systems(ANFIS)and artificial neural networks(ANNs).Wind speed and direction were considered as essential input parameters,with wind energy as the target parameter,and models are thoroughly evaluated using metrics such as the mean absolute percentage error(MAPE),coefficient of determination(R~2),and mean absolute error(MAE).The findings accentuate the superior performance of the SVM,which delivered the lowest MAPE(2.42%),the highest R~2(0.95),and the lowest MAE(71.21%)compared with actual values,while ANFIS was less effective in this context.The main aim of this comparative analysis was to rank the models to move to the next step in improving the least efficient methods by combining them with optimization algorithms,such as metaheuristic algorithms. | Doha Bouabdallaoui Touria Haidi Faissal Elmariami Mounir Derri El Mehdi Mellouli | 2023 | Global Energy Interconnection2023，6，6： | 0 |
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