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| 1 | Prostate cancer in Asia:A collaborative report显示文摘The incidence of prostate cancer(PCa)within Asian population used to be much lower than in the Western population;however,in recent years the incidence and mortality rate of PCa in some Asian countries have grown rapidly.This collaborative report summarized the latest epidemiology information,risk factors,and racial differences in PCa diagnosis,current status and new trends in surgery management and novel agents for castration-resistant prostate cancer.We believe such information would be helpful in clinical decision making for urologists and oncologists,health-care ministries and medical researchers. | Rui Chen Shancheng Ren 无 Ming Kwong Yiu Ng Chi Fai Wai Sam Cheng Lap Hong Ian Seiji Naito Tadashi Matsuda Elijah Kehinde Ali Kural Jason Yichun Chiu Rainy Umbas Qiang Wei Xiaolei Shi Liqun Zhou Jian Huang Yiran Huang Liping Xie Lulin Ma Changjun Yin Danfeng Xu Kexin Xu Zhangqun Ye Chunxiao Liu Dingwei Ye Xin Gao Qiang Fu Jianquan Hou Jianlin Yuan Dalin He Tiejun Pan Qiang Ding Fengshuo Jin Benkang Shi Gongxian Wang Xiuheng Liu Dongwen Wang Zhoujun Shen Xiangbo Kong Wanhai Xu Yaoliang Deng Haibo Xia Alexa NCohen Xu Gao Chuanliang Xu Yinghao Sun | 2014 | Asian Journal of Urology2014，1，1： | 13 |
| 2 | NIR-II ?uorescence in vivo confocal microscopy with aggregation-induced emission dots显示文摘Significantly reduced tissue scattering of fluorescence signals in the second near-infrared(NIR-Ⅱ,1,000–1,700 nm)spectral region offers opportunities for large-depth in vivo bioimaging.Nowadays,most reported works concerning NIR-II fluorescence in vivo bioimaging are realized by wide-field illumination and 2D-arrayed detection(e.g.,via InGaAs camera),which has high temporal resolution but limited spatial resolution due to out-of-focus signals.Combining NIR-II fluorescence imaging with confocal microscopy is a good approach to achieve high-spatial resolution visualization of biosamples even at deep tissues.In this presented work,a NIR-II fluorescence confocal microscopic system was setup.By using a kind of aggregation-induced emission(AIE)dots as NIR-II fluorescent probes,800 lm-deep 3D in vivo cerebrovascular imaging of a mouse was obtained,and the spatial resolution at 700 lm depth could reach 8.78 lm.Moreover,the time-correlated single photon counting(TCSPC)technique and femtosecond laser excitation were introduced into NIR-II fluorescence confocal microscopy,and in vivo confocal NIR-II fluorescence lifetime microscopic imaging(FLIM)of mouse cerebral vasculature was successfully realized. | Wenbin Yu Bing Guo Hequn Zhang Jing Zhou Xiaoming Yu Liang Zhu Dingwei Xue Wen Liu Xianhe Sun Jun Qian | 2019 | Science Bulletin2019，64，6： | 10 |
| 3 | Feedback Regulation of FLC by FLOWERING LOCUS T (FT) and FD through a 5’ FLC Promoter Region in Arabidopsis显示文摘Dear Editor, Recently, it was reported that the florigenic FT protein bound to a 3’ region of the potent floral repressor FLC (FLOWERING LOCUS C) to activate the expression of long noncoding antisense RNAs known as COOLAIR and consequently repress FLC expression to control flowering time and seed dormancy in Arabidopsis (Chen and Penfield, 2018). Here, we show that FT represses FLC expression through a 5' promoter region, but not COOLAIR. | Xiao Luo Tao Chen Xiaolin Zeng Dingwei He Yuehui He | 2019 | Molecular Plant2019，12，3： | 10 |
| 4 | Shale Gas Formation and Occurrence in China: An Overview of the Current Status and Future Potential显示文摘Shale gas is one of the most promising unconventional resources both in China and abroad. It is known as a form of self-contained source-reservoir system with large and continuous dimensions. Through years of considerable exploration efforts, China has identified three large shale gas fields in the Fuling, Changning and Weiyuan areas of the Sichuan Basin, and has announced more than 540 billion m^3 of proven shale gas reserves in marine shale systems. The geological theories for shale gas development have progressed rapidly in China as well. For example, the new depositional patterns have been introduced for deciphering the paleogeography and sedimentary systems of the Wufeng shale and Longmaxi shale in the Sichuan Basin. The shale gas storage mechanism has been widely accepted as differing from conventional natural gas in that it is adsorbed on organic matter or a mineral surface or occurs as free gas trapped in pores and fractures of the shale. Significant advances in the techniques of microstructural characterization have provided new insights on how gas molecules are stored in micro- and nano-scale porous shales. Furthermore, newly-developed concepts and practices in the petroleum industry, such as hydraulic fracturing, microseismic monitoring and multiwell horizontal drilling, have made the production of this unevenly distributed but promising unconventional natural gas a reality. China has 10–36 trillion m^3 of promising shale gas among the world's whole predicted technically recoverable reserves of 206.6 trillion m^3. China is on the way to achieving its goal of an annual yield of 30–50 billion m^3 by launching more trials within shale gas projects. | ZOU Caineng YANG Zhi PAN Songqi CHEN Yanyan LIN Senhu HUANG Jinliang WU Songtao DONG Dazhong WANG Shufang LIANG Feng SUN Shasha HUANG Yong WENG Dingwei | 2016 | Acta Geologica Sinica(English Edition)2016，90，4： | 9 |
| 5 | Percent free prostate-specific antigen for prostate cancer diagnosis in Chinese men with a PSA of 4.0-10.0 ng/mL:Results from the Chinese Prostate Cancer Consortium显示文摘Objective:To test the diagnostic performance of percent free prostate-specific antigen(%fPSA)in predicting any prostate cancer(PCa)and high-grade prostate cancer(HGPCa)in a retrospective multi-center biopsy cohort with a PSA level of 4.0e10.0 ng/mL in China.Methods:Consecutive patients with a PSA of 4.0-10.0 ng/mL who underwent transrectal ultrasound-guided biopsy were enrolled at 16 Chinese medical centers from January 1st,2010 to December 31st,2013.Total and free serum PSA determinations were performed using three types of electro-chemiluminescence immunoassays recalibrated to the World Health Organization(WHO)standard.The diagnostic accuracy of PSA,%fPSA,and %fPSA in combination with PSA(%fPSA t PSA)was determined using the area under the receiver operating characteristic(ROC)curve(AUC).Results:A total of 2310 consecutive men with PSA levels between 4.0 and 10.0 ng/mL were included,and the detection rate of PCa was 25.1%.The AUC of%fPSA and %fPSA t PSA in predicting any PCa was superior to PSA alone in men aged≥60 years(0.623 vs.0.534,p<0.0001)but not in men aged 40e59 years(0.517 vs.0.518,p=0.939).Similar result was yield in predicting HGPCa.Conclusion:In a clinical setting of Chinese men with 4.0e10.0 ng/mL PSA undergoing initial prostate biopsy,adding %fPSA to PSA can moderately improve the diagnostic accuracy for any PCa and HGPCa compared with PSA alone in patients≥60 but not in patients aged 40-59 years. | Rui Chen Liping Xie Xiaobing Cai Yiran Huang Liqun Zhou Lulin Ma Xu Gao Chuanliang Xu Shancheng Ren Pengfei Shao Danfeng Xu Kexin Xu Zhangqun Ye Chunxiao Liu Dingwei Ye Li Lu Qiang Fu Jianquan Hou Jianlin Yuan Dalin He Tie Zhou Fubo Wang Biming He Yinghao Sun | 2015 | Asian Journal of Urology2015，2，2： | 8 |
| 6 | Survey of E-Commerce Modeling and Optimization Strategies显示文摘Electronic commerce is impacting almost all commercial activities. The resulting emerging commercial activities bring with them many new modeling and optimization problems. This survey reviews pioneering works in this new area, covering topics in advertising strategy, web page design, automatic pricing, auction methods, brokerage strategy, and customer behavior analysis. Mathematical models for problems in these areas and their solution algorithms are discussed. In addition to presenting and commenting on these works, we also discuss possible extensions and related problems. The objective of this survey is to encourage more researchers to pay attention to this emerging area. | WANG Dingwei NUTTLE Henry L.W. FANG Shu-Cherng | 2005 | Tsinghua Science and Technology2005，10，z1： | 7 |
| 7 | High-throughput sequencing-based genome-wide identification of micro RNAs expressed in developing cotton seeds显示文摘Micro RNAs(mi RNAs) have been shown to play critical regulatory roles in gene expression in cotton. Although a large number of mi RNAs have been identified in cotton fibers, the functions of mi RNAs in seed development remain unexplored. In this study, a small RNA library was constructed from cotton seeds sampled at 15 days post-anthesis(DPA) and was subjected to high-throughput sequencing. A total of 95 known mi RNAs were detected to be expressed in cotton seeds. The expression pattern of these identified mi RNAs was profiled and 48 known mi RNAs were differentially expressed between cotton seeds and fibers at 15 DPA. In addition, 23 novel mi RNA candidates were identified in 15-DPA seeds. Putative targets for 21 novel and 87 known mi RNAs were successfully predicted and 900 expressed sequence tag(EST) sequences were proposed to be candidate target genes, which are involved in various metabolic and biological processes, suggesting a complex regulatory network in developing cotton seeds. Furthermore, mi RNA-mediated cleavage of three important transcripts in vivo was validated by RLM-5′ RACE. This study is the first to show the regulatory network of mi RNAs that are involved in developing cotton seeds and provides a foundation for future studies on the specific functions of these mi RNAs in seed development. | WANG YanMei DING Yan YU DingWei XUE Wei LIU JinYuan | 2015 | Science China(Life Sciences)2015，58，8： | 7 |
| 8 | Particle swarm optimization with a leader and followers显示文摘指野鹅成群的飞行机制,我们与一个领导人和追随者一起建议粒子群优化(PSO ) 的一个新奇版本。它被叫作鹅队优化(GTO ) 。象鹅角色分割,平行原则,总数原则和分开的原则那样的鹅队飞行的基本特征在推荐算法被实现。在 GTO,一个队被粒子与一个领导人和一些追随者一起形成。领导人的角色是决定搜索方向。追随者个别地根据他们的距离决定他们的飞的模式到领导人。因此,一个宽区域能被探索,粒子碰撞能确实被避免。当 GTO 被用于复杂非线性的函数的四个基准例子时,它比标准 PSO 有更好的计算表演。 | Junwei Wang Dingwei Wang | 2008 | Progress in Natural Science:Materials International2008，18，11： | 6 |
| 9 | Adjuvant hormone therapy after radical prostatectomy in highrisk localized and locally advanced prostate cancer: First multicenter, observational study in China显示文摘Objective: Potential of combined androgen blockade(CAB) has not been explored extensively in Chinese males with prostate cancer(PCa). Therefore, this study evaluated the 2-year prostate-specific antigen(PSA) recurrence rate and quality of life(Qo L) in patients with high-risk localized and locally advanced PCa receiving adjuvant hormone therapy(HT) after radical prostatectomy(RP).Methods: This prospective, multicenter, observational study conducted in 18 centers across China enrolled patients with high-risk factor(preoperative PSA>20 ng/m L or Gleason score >7) or locally advanced PCa. Different adjuvant HT were administered after RP according to investigator’s decision in routine clinical practice.Relationship of baseline and postoperative characteristics was assessed with recurrence rate. PSA recurrence rate and Functional Assessment of Cancer Therapy-Prostate(FACT-P) Qo L scores were recorded at 12 months and 24 months. Kaplan-Meier analysis was used to construct the PSA recurrence rate during follow-up.Results: A total of 189 patients(mean age: 66.9±6.5 years) were recruited, among which 112(59.3%) patients showed serum PSA>20 ng/m L preoperatively. The highest postoperative pathological advancement noticed was from clinical T2(c T2) to pathological T3(p T3)(43.9%) stage. The majority of the patients(66.1%) received CAB as adjuvant HT, for a median duration of 20.0 months. The least recurrence(15.2%) was noticed in patients treated with CAB, followed by those treated with luteinizing hormone-releasing hormone agonist(LHRHa)(16.1%), and antiandrogen(19.0%), with non-significant difference noted among the groups. None of the baseline or postoperative characteristics was related with PSA recurrence in our study. The 24-month FACT-P Qo L score of119 patients treated for >12 months showed significant improvement above baseline compared with those treated for ≤12 months.Conclusions: Adjuvant CAB therapy after RP showed reduction trend in 2-year PSA recurrence rate in highrisk Chinese patients with localized and locally advanced PCa, compared with adjuvant anti-androgens(AA) or LHRHa therapy. Further long-term therapy(>12 months) significantly improved Qo L compared to short-term HT therapy, suggesting the beneficial effect of long-term CAB therapy in improving Qo L. | Dingwei Ye Wei Zhang Lulin Ma Chuanjun Du Liping Xie Yiran Huang Qiang Wei Zhangqun Ye Yanqun Na | 2019 | Chinese Journal of Cancer Research2019，31，3： | 4 |
| 10 | A Novel Algorithm Supporting QoS for Traffic Engineering in MPLS Networks显示文摘A Queue Tuning Algorithm (QTA) supporting Quality of Service (QoS) for traffic engineering in Multi-Protocol Label Switching (MPLS) networks is proposed. The algorithm aims at mapping different traffic onto different queues according to the result of Cyclic Redundancy Check (CRC),which can preserve the order of packets within a flow in traffic. Simulation indicates that QTA can meet the need of traffic with QoS requirement while realizing load balancing in MPLS | CUIBing-feng ZHANGXu DINGWei | 2004 | The Journal of China Universities of Posts and Telecommunications2004，11，3： | 4 |
| 11 | Vertical structure of longitudinal differences in electron densities at mid-latitudes显示文摘由使用为气象学,电离层,和气候卫星观察系统的星座,观察,和全球电离层和 Thermosphere 为模拟建模,在电子密度 Ne 的纵的差别的高度的依赖被学习在中间纬度第一次。不同高度的依赖被揭示:(1 ) 在里面北(南部) 半球,在在低于 180 的高度的白天主要有 wave-1 变化 ? 在超过 220 的一整个天的 km,而是 wave-2 (wave-1 ) 变化 ? km;(2 ) 转变(或分离) 层主要在白天发生在 180 和 220 以内 ? km,在更低的高度的从那的出现颠倒的纵的变化。太阳的照明是为在更低的高度的 Ne 的带的差别的嘴巧的机制之一。在更高的高度,中立的风和太阳的照明起了重要作用。中立的风效果在 EuropeanAsian 部门在 Ne 说明了纵的差别。中立作文变化和中立的风效果两个都贡献了转变层的形成。 | Hui Wang Dingwei Liu Jing Zhang | 2016 | Science Bulletin2016，61，3： | 4 |
| 12 | ABR Flow Control Algorithm in ATM Networks: a Neural Network Approach显示文摘A Neural Network( NN ) approach to ABR flow control algorithm in ATM networks is proposed. The NN predicts the queue length, its variation and possible cell loss, then regulates the source rate adaptively. Therefore, more appropriate value of the explicit rate can be determined in the corresponding field of the RM cells. This approach performs better than the traditional static feedback control. Additionally, the performance of this algorithm under CBR background traffic is discussed, and the simulatino results show that the neural network is also efficient. | GAOHong DINGWei | 2000 | The Journal of China Universities of Posts and Telecommunications2000，7，4： | 3 |
| 13 | A phase 3,double-blind,randomized placebo-controlled efficacy and safety study of abiraterone acetate in chemotherapynaı¨ve patients with mCRPC in China,Malaysia,Thailand and Russia显示文摘Objective:This double-blind,placebo-controlled phase 3 study was designed to compare efficacy and safety of abiraterone acetate+prednisone(abiraterone)to prednisone alone in chemotherapy-naı¨ve,asymptomatic or mildly symptomatic metastatic castrationresistant prostate cancer(mCRPC)patients from China,Malaysia,Thailand and Russia.Methods:Adult chemotherapy-naı¨ve patients with confirmed prostate adenocarcinoma,Eastern Cooperative Oncology Group(ECOG)performance status(PS)grade 0e1,ongoing androgen deprivation(serum testosterone<50 ng/dL)with prostate specific antigen(PSA)or radiographic progression were randomized to receive abiraterone acetate(1000 mg,QD)t prednisone(5 mg,BID)or placebo t prednisone(5 mg,BID),until disease progression,unacceptable toxicity or consent withdrawal.Primary endpoint was improvements in time to PSA progression(TTPP).Results:Totally,313 patients were randomized(abiraterone:n Z 157;prednisone:n Z 156);and baseline characteristics were balanced.At clinical cut-off(median follow-up time:3.9 months),80% patients received treatment(abiraterone:n Z 138,prednisone:n Z 112).Median time to PSA progression was not reached with abiraterone versus 3.8 months for prednisone,attaining 58%reduction in PSA progression risk(HR=0.418;p<0.0001).Abirateronetreated patients had higher confirmed PSA response rate(50%vs.21%;relative odds=2.4;p<0.0001)and were 5 times more likely to achieve radiographic response than prednisonetreated patients(22.9%vs.4.8%,p=0.0369).Median survival was not reached.Most common(≥10% abiraterone vs.prednisone-treated)adverse events:bone pain(7%vs.14%),pain in extremity(6%vs.12%),arthralgia(10%vs.8%),back pain(7%vs.11%),and hypertension(15%vs.14%).Conclusion:Interim analysis confirmed favorable benefit-to-risk ratio of abiraterone in chemotherapy-naı¨ve men with mCRPC,consistent with global study,thus supporting use of abiraterone in this patient population. | Dingwei Ye Yiran Huang Fangjian Zhou Keji Xie Vsevolod Matveev Changling Li Boris Alexeev Ye Tian Mingxing Qiu Hanzhong Li Tie Zhou Peter De Porre Margaret Yu Vahid Naini Hongchuan Liang Zhuli Wu Yinghao Sun | 2017 | Asian Journal of Urology2017，4，2： | 3 |
| 14 | Fuzzy Logic QoS Dynamic Source Routing for Mobile Ad Hoc Networks显示文摘Considering the characters of dynamic topology and the imprecise state information in mobile ad hoc network,we propose a Fuzzy Logic QoS Dynamic Source Routing (FLQDSR) algorithm based on Dynamic Source Routing (DSR) protocol while adopting fuzzy logic to select the appropriate QoS routing in multiple paths which are searched in parallel. This scheme considers not only the bandwidth and end-to-end delay of routing, but also the cost of the path. On the otherh and the merit of using fuzzy logic is that it can be implemented by hardware. This makes the realization of the scheme easier and faster. However our algorithm is based on DSR, the maximal hop count should be less than 10, i.e., the scale of mobile ad hoc network should not be very large. Simulation results show that.FLQDSR can tolerate a high degree of information imprecision by adding the fuzzy logic module which integrates the QoS requirements of application and the routing QoS parameters to determine the most qualified one in every node. | ZHANGXu CHENGSheng FENGMei-yu DINGWei | 2004 | The Journal of China Universities of Posts and Telecommunications2004，11，4： | 3 |
| 15 | Hot-band absorption of indocyanine green for advanced anti-stokes fluorescence bioimaging显示文摘Bright anti-Stokes fluorescence(ASF)in the first near-infrared spectral region(NIR-I,800 nm–900 nm)under the excitation of a 915 nm continuous wave(CW)laser,is observed in Indocyanine Green(ICG),a dye approved by the Food and Drug Administration for clinical use.The dependence of fluorescence intensity on excitation light power and temperature,together with fluorescence lifetime measurement,establish this ASF to be originated from absorption from a thermally excited vibrational level(hot-band absorption),as shown in our experiments,which is stronger than the upconversion fluorescence from widely-used rare-earth ion doped nanoparticles.To test the utility of this ASF NIR-I probe for advanced bioimaging,we successively apply it for biothermal sensing,cerebral blood vessel tomography and blood stream velocimetry.Moreover,in combination with L1057 nanoparticles,which absorb the ASF of ICG and emit beyond 1100 nm,these two probes generate multi-mode images in two fluorescent channels under the excitation of a single 915 nm CW laser.One channel is used to monitor two overlapping organs,urinary system&blood vessel of a live mouse,while the other shows urinary system only.Using in intraoperative real-time monitoring,such multi-mode imaging method can be beneficial for visual guiding in anatomy of the urinary system to avoid any accidental injury to the surrounding blood vessels during surgery. | Jing Zhou Xiaoxiao Fan Di Wu Jie Liu Yuhuang Zhang Zikang Ye Dingwei Xue Mubin He Liang Zhu Zhe Feng Andrey N.Kuzmin Wen Liu Paras N.Prasad Jun Qian | 2021 | Light(Science & Applications)2021，10，10： | 3 |
| 16 | Analysis of Reliability for 3-State Device Network with Link-Capacities显示文摘This paper presents a concept of the 3-state device system with link-capacity, whichcan, besides its normal operative state, assume two different failure states: an open-mode and ashorted-mode failure state. The 3-state system reliability analysis often uses flow required andprobability of the device to compute the probability of the system with link-capacity. We use themethod of max-flow and min-cut theorem, give four theorems to reduce 3-state device network withlink-capacity reliability problems to 2-state problems. For practical, relevant network sizes (up to100 components), the algorithm is fast and efficient. | Zhang Ying Liu Yanqiu(Department of Mathematics and Physics, Shenyang Polytechnic University,110023, P. R. China)Wang Dingwei(Department of Systems Engineering, Northeastern University,Shenyang 110023, P. R.China) | 1999 | Journal of Systems Engineering and Electronics1999，10，2： | 2 |
| 17 | Bound ^(14)C-metsulfuron-methyl residue in soils显示文摘Bound residue(BR) of 14 C-metsulfuron-methyl ( 14 C-BR) in seven kinds of soil was significantly negative-related to soil pH and positive-related to the clay content during the initial 20 d of incubation, but only was significantly negative-related to soil pH after 30 d incubation. Again, the soil pH was found to be the dominant factor affecting BR formation from 14 C-metsulfuron-methyl among the basic properties(soil pH, clay, OM and CEC etc.) of soil. The maximum content of 14 C-BR in the 7 soils accounted for 19.3%-52.6% of applied amount. In addition, the composition of the 14 C-BR in fluvio marine yellow loamy(S 7) at the 90 d of incubation was identified using the coupling technique of LC-MS and isotope tracing method. The results showed that the 14 C-[2-amino-4-hydroxyl-6-methyl-1, 3, 5]-triazine, 14 C-[2-amino-4-methoxy-6-methyl-1, 3, 5]-triazine and 14 C-metsulfuron-methyl parent compound constituted the main components of the BR derived from 14 C-metsulfuron-methyl in the S 7. The relative percentage of the three compounds accounted for 41.4%, 35.8% and 19.3% of total recovery radioactivity, respectively. The results also indicated that a non-radioactive component, 2-methylformate-benzenesulfonyl-isocyanate, one of the degraded products of metsulfuron-methyl in soil, was also found to be one of the components of the BR. The parent compound in BR can well explain the phytotoxic effect on substitution crops caused by the BR derived from metsulfuron-methyl in soil. | YEQing-fu DINGWei WANGHai-yan HANAi-liang SUNJin-he | 2005 | Journal of Environmental Sciences2005，17，2： | 2 |
| 18 | A Rate of Convergence of Physics Informed Neural Networks for the Linear Second Order Elliptic PDEs显示文摘In recent years,physical informed neural networks(PINNs)have been shown to be a powerful tool for solving PDEs empirically.However,numerical analysis of PINNs is still missing.In this paper,we prove the convergence rate to PINNs for the second order elliptic equations with Dirichlet boundary condition,by establishing the upper bounds on the number of training samples,depth and width of the deep neural networks to achieve desired accuracy.The error of PINNs is decomposed into approximation error and statistical error,where the approximation error is given in C2 norm with ReLU^(3)networks(deep network with activation function max{0,x^(3)})and the statistical error is estimated by Rademacher complexity.We derive the bound on the Rademacher complexity of the non-Lipschitz composition of gradient norm with ReLU^(3)network,which is of immense independent interest. | Yuling Jiao Yanming Lai Dingwei Li Xiliang Lu Fengru Wang Yang Wang Jerry Zhijian Yang | 2022 | Communications in Computational Physics2022，31，4： | 2 |
| 19 | Application of fluorescence in situ hybridization in the detection of bladder transitional-cell carcinoma: A multi-center clinical study based on Chinese population显示文摘Objective:To evaluate the diagnostic value of fluorescence in situ hybridization(FISH)in bladder cancer.Methods:We enrolled healthy volunteers and patients who were clinically suspected to have bladder cancer and conducted FISH tests and cytology examinations from August 2007 to December 2008.Receiver operating characteristic(ROC)curve analysis was performed and the area under curve(AUC)values were calculated for both the FISH and urine cytology tests.Results:A cohort of 988 healthy volunteers was enrolled to establish a reference range for the normal population.A total of 4807 patients with hematuria were prospectively,randomly enrolled for the simultaneous analysis of urine cytology,FISH testing,and a final diagnosis as determined by the pathologic findings of a biopsy or a surgically-excised specimen.Overall,the sensitivity of FISH in detecting transitional-cell carcinoma was 82.7%,while that of cytology was 33.4%(p<0.001).The sensitivity values of FISH for non-muscle invasive and muscle invasive bladder transitional-cell carcinoma were 81.7%and 89.6%,respectively(p=0.004).The sensitivity values of FISH for low and high grade bladder cancer were 82.6%and 90.1%,respectively(p=0.002).Conclusion:FISH is significantly more sensitive than voided urine cytology for detecting bladder cancer in patients evaluated for gross hematuria at all cancer grades and stages.Higher sensitivity using FISH was obtained in high grade and muscle invasive tumors. | Liqun Zhou Kaiwei Yang Xuesong Li Yi Ding Dawei Mu Hanzhong Li Yong Yan Jinyi Li Dongwen Wang Wei Li Yulong Cong Jiangping Gao Kewei Ma Yajun Xiao Sheng Zhang Hongyi Jiang Weilie Hu Qiang Wei Xunbo Jin Zhichen Guan Qingyong Liu Danfeng Xu Xin Gao Yongguang Jiang Weimin Gan Guang Sun Qing Wang Yanhui Liu Jianquan Hou Liping Xie Xishuang Song Fengshuo Jin Jiafu Feng Ming Cai Zhaozhao Liang Jie Zhang Dingwei Ye Lin Qi Lulin Ma Jianzhong Shou Yuping Dai Jianyong Shao Ye Tian Shizhe Hong Tao Xu Chuize Kong Zefeng Kang Yuexin Liu Xun Qu Benkang Shi Shaobin Zheng Yi Lin Shujie Xia Dong Wei Jianbo Wu Weiling Fu Zhiping Wang Jianbo Liang | 2019 | Asian Journal of Urology2019，6，1： | 2 |
| 20 | Path selection model and algorithm for emergency logistics management显示文摘 | Yuan Y Dingwei W | 2009 | Computers & In- dustrial Engineering2009，56，： | 1 |
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