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| 1 | A high-quality genome assembly of quinoa provides insights into the molecular basis of salt bladder-based salinity tolerance and the exceptional nutritional value显示文摘 | Changsong Zou Aojun Chen Lihong Xiao Heike M Muller Peter Ache Georg Haberer Meiling Zhang Wei Jia Ping Deng Ru Huang Daniel Lang Feng Li Dongliang Zhan Xiangyun Wu Hui Zhang Jennifer Bohm Renyi Liu Sergey Shabala Rainer Hedrich Jian-Kang Zhu Heng Zhang | 2017 | Cell Research2017，27，11： | 22 |
| 2 | Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection显示文摘Structural principles underlying the composition and synergistic mechanisms of protective monoclonal antibody cocktails are poorly defined.Here,we exploited antibody cooperativity to develop a therapeutic antibody cocktail against SARS-CoV-2.On the basis of our previously identified humanized cross-neutralizing antibody H014,we systematically an a lyzed a fully human n aive antibody library and rationally identified a potent neutralizing antibody partner,P17,which confers effective protection in animal model.Cryo-EM studies dissected the nature of the P17 epitope,which is SARS-CoV-2 specific and distinctly different from that of HOI4.High-resolution structure of the SARS-CoV-2 spike in complex with HOM and P17,together with functional investigations revealed that in a two-antibody cocktail,synergistic neutralization was achieved by S1 shielding and conformational locking,thereby blocking receptor attachment and viral membrane fusion,conferring high potency as well as robustness against viral mutation escape.Furthermore,cluster analysis identified a hypothetical 3rd antibody partner for further reinforcing the cocktail as pan-SARS-CoVs therapeutics. | Hangping Yao Yao Sun Yong-Qiang Deng Nan Wang Yongcong Tan Na-Na Zhang Xiao-Feng Li Chao Kong Yan-Peng Xuc Qi Chen Tian-Shu Cao Hui Zhao Xintian Yan Lei Cao Zhe Lv Dandan Zhu Rui Feng Nanping Wu Wenhai Zhang Yuhao Hu Keda Chen Rong-Rong Zhang Qingyu Lv Shihui Sun Yunhua Zhou Run Yan Guan Yang Xinglu Chanjuan Liu Xiangyun Lu Linfang Cheng Hongying Qiu Xing-Yao Huang Tianhao Weng Danrong Shi Weidong Jiang Junbin Shao Lei Wang Jie Zhang Tao Jiang Guojun Lang Cheng-Feng Qinc Lanjuan Li Xiangxi Wang | 2021 | Cell Research2021，31，1： | 5 |
| 3 | Phyto-phospholipid complexes(phytosomes): A novel strategy to improve the bioavailability of active constituents显示文摘Although active constituents extracted from plants show robust in vitro pharmacological effects, low in vivo absorption greatly limits the widespread application of these compounds. A strategy of using phyto-phospholipid complexes represents a promising approach to increase the oral bioavailability of active constituents, which is consist of ‘‘label-friendly'phospholipids and active constituents. Hydrogen bond interactions between active constituents and phospholipids enable phospholipid complexes as an integral part. This review provides an update on four important issues related to phyto-phospholipid complexes: active constituents, phospholipids, solvents, and stoichiometric ratios. We also discuss recent progress in research on the preparation, characterization, structural verification, and increased bioavailability of phyto-phospholipid complexes. | Mei Lu Qiujun Qiu Xiang Luo Xinrong Liu Jing Sun Cunyang Wang Xiangyun Lin Yihui Deng Yanzhi Song | 2019 | Asian Journal of Pharmaceutical Sciences2019，14，3： | 4 |
| 4 | Ferroelectricity of nanocrystalline BaTiO_3 ceramics by first principle calculation显示文摘The vibrational modes of BaTiO3 in different crystalline phases have been investigated by means of density functional theory pseudo potential method.The evidence of tetragonal to orthorhombic and orthorhombic to rhombohedral phase transitions present for 8 nm BaTiO3 ceramics further demonstrates that the similar successive transitions in 8 nm BaTiO3 ceramics from rhombohedral to orthorhombic,tetragonal and cubic transitions are as those in coarse BaTiO3 ceramics. | DENG XiangYun ZHANG HaiTao LI Ting LI DeJun LI JianBao WANG XiaoHui LI LongTu | 2010 | Chinese Science Bulletin2010，55，20： | 4 |
| 5 | The effects of modulation period,modulation ratio,and deposition temperature on microstructure and mechanical properties of ZrB_2/W multilayers显示文摘Monolithic ZrB2,W coatings and ZrB2/W multilayers with different modulation periods and modulation ratios were synthesized by ion beam assisted deposition at room temperature and 400°C.X-ray diffraction (XRD),scanning electron microscopy (SEM),surface profiler,and nanoindention were employed to investigate the influences of the deposition temperature and the modulation period on the growth,textures,interface structure,and mechanical properties of the multilayers.The results indicated that the multilayer with modulation period of 13 nm synthesized at room temperature possessed a higher hardness of 23.8 GPa.Deposition temperature gave a significant contribution to mechanical property enhancement.The 400°C-deposition temperature led to a maximum hardness and elastic modulus value of 32.1 and 399.1 GPa for ZrB2/W multilayer with a modulation period of 6.7 nm.Its critical load increased to 42.8 mN and residual stress decreased to -0.7 GPa.A higher deposition temperature can cause an increase in interfacial atomic mixture and mobility of surface species,which induceds an increase in areal atomic density and dislocation pinning.These results as well as small nanoscale grain sizes should be related to hardness increase. | LIU MengYin,TAN Ming,LIU GuangQing,WANG HaiYuan,XUE FengYing,DENG XiangYun & LI DeJun College of Physics and Electronic Information Science,Tianjin Normal University,Tianjin 300387,China | 2010 | Science China(Technological Sciences)2010，53，9： | 4 |
| 6 | In vitro comparison of the hemocompatibility of diamond-like carbon and carbon nitride coatings with different atomic percentages of N显示文摘Carbon nitride (CNx) and diamond-like carbon (DLC) coatings were prepared by dc magnetron sputtering at room temperature. Different partial pressures of N2 were used to synthesize CNx to evaluate the relationship between the atomic percentage of nitrogen and hemocompatibility. Auger electron spectroscopy and atomic force microscopy indicated atomic percentages of N of 0.12 and 0.22 and that the CNx coatings were smooth. An in vitro study of the hemocompatibility of the coatings revealed that both CNx coatings had better anticoagulant properties and lower platelet adhesion than DLC. Compared with CN0.12, the CN0.22 coating showed longer dynamic clotting time (about 42 min), static clotting time (23.6 min) and recalcification time (45.6 s), as well as lower platelet adhesion (102 cells μm 2), aggregation, and activation. The presence of nitrogen in the CNx coatings induced their enhanced hemocompatibility compared with DLC. | ZHAO MengLi LI DeJun ZHANG YiTeng GUO MeiXian DENG XiangYun GU HanQing WAN RongXin | 2012 | Science China(Life Sciences)2012，55，4： | 3 |
| 7 | 显示文摘 | Deng Xiangyun Wang Xiaohui Wen Hai | 2006 | Journal of the American Ceramic Society2006，89，： | 1 |
| 8 | Influence of modulation ratio on structure and properties of nanoscale ZrB_2/ZrAlN multilayered coatings显示文摘ZrB2/ZrAlN multilayered coatings with various modulation ratios(t ZrB2:t ZrAlN)and constant modulation periods were prepared by magnetron sputtering system at room temperature.SEM,XRD,surface profiler and nano-indenter were employed to investigate the influences of tZ rB 2:tZrAlNon the microstructure and mechanical properties of the coatings.Sharp interfaces and nanoscale multilayered modulation were confirmed by SEM.The multilayer with modulation period of 40 nm and ratio of 3:1 displayed the highest hardness(36.4 GPa)and critical fracture load(76.477 mN)with lower stress.The polycrystalline structure and multilayered modulate structure were directly responsible for the enhanced mechanical properties. | LI DeJun 1,KANG YuanBin 1,DONG Lei 1,DENG XiangYun 1,LIU Hao 2 &SUN XueLiang 2 1College of Physics and Electronic Information Science,Tianjin Normal University,Tianjin 300387,China 2 Department of Mechanical&Materials Engineering,University of Western Ontario,London ON,Canada | 2010 | Science China(Technological Sciences)2010，53，3： | 1 |
| 9 | Preparation and pro-perties of mullite-bonded porous SiC ceramics using porousalumina as oxide显示文摘 | Bai Chengying Deng Xiangyun | 2014 | Mater Charact2014，90，： | 1 |
| 10 | Influence of Ar/N_2 Flow Rate on Structure and Property for TaN/NbN Multilayered Coatings显示文摘有 nanoscale 双性人层时期的 TaN/NbN multilayered 涂层被 RF (收音机频率)以不同 Ar/N2 流动率综合磁控管 sputtering.XRD (X光检查衍射) andNano Indenter 系统被采用调查 Ar/N2 流动率的影响(F_( Ar ):F_( N2 ))在微观结构和机械性质上涂层。低角度的 XRD 模式显示了定义 awell 的作文调整和 multilayered 涂层的层结构。所有 multilayered 涂层几乎比 rule-of-mixtures 价值揭示了更高的坚硬整体黝黑并且 NbNcoatings.At F_( Ar ):F_( N2 ) =10 , multilayered 涂层拥有了理想的坚硬,有弹性的模量,内部压力,和破裂抵抗,在另外的 Ar/N2 flowrates.The 与相比综合了有强壮的混合的分层的结构黝黑( 110 ),( 111 ),( 200 )并且 Nb2N ( 101 )质地应该与提高的机械性质有关。 | Xuehua ZHANG Yuanbin KANG Sipeng LIU Qiang LI Ying YANG Xiangyun DENG Dejun LI | 2007 | Journal of Materials Science & Technology2007，23，4： | 1 |
| 11 | Generalized assembly of sandwich-like 0D/2D/0D heterostructures with highly exposed surfaces toward superior electrochemical performances显示文摘Heterostructures composed of two-dimensional(2D)nanosheets and zero-dimensional(0D)nanoparticles(NPs)have attracted increasing attention because of the synergy arising from the coupling interactions between the two mixed-dimensional components.Despite recent advances,it remains a challenge to fabricate 2D/0D heterostructures with clean and accessible surfaces,which is highly desirable for the diversity of catalytic,sensing,and energy storage applications.Herein,we report a generalized methodology that enables the facile assembly of sandwich-like 0D/2D/0D heterostructures with facilitated mass-transport channels and exposed surface active sites.A ligand-exchange strategy with HBF4 is employed to strip off the surface-coating ligands of colloidal NPs,rendering them positively charged and dispersible in polar solvents.This allows subsequent electrostatic assembly of NPs with oppositely charged 2D nanosheets to afford sandwich-like 0D/2D/0D heterostructures.The barely covered surfaces and the advantageous architectures of such sandwich-like 0D/2D/0D heterostructures induce the desired synergistic effect,making them particularly suitable for electrochemical energy storage and conversion.We demonstrate this by employing MXene/NiFe_(2)O_(4) and MXene/Fe3O4 heterostructures for high-performance electrocatalytic oxygen evolution and supercapacitors,respectively. | Shuqing Xue Guanhong Wu Mingzhong Li Zihan Liu Yuwei Deng Wenqian Han Xuanyu Lv Siyu Wan Xiangyun Xi Dong Yang Angang Dong | 2022 | Nano Research2022，15，1： | 0 |
| 12 | Fabrication of flexible α-MnO_2 nanowire membranes with superior mechanical strength显示文摘The Assembly of one-dimensional(1D)nanostructures such as nanowires/nanorods/nanotubes into twodimensional(2D)macrostructured films is attracting considerable research interest because of their unique properties and wide applications.In this study,flexible membranes were successfully fabricated using a-MnO2nanowires synthesized through a hydrothermal method.The effects of thickness and post-annealing temperature on the mechanical properties of the membranes were investigated in detail.Nano-indentation measurements showed that the modulus of the as-prepared 11.75 lm-thick membrane reached5.765 GPa,and the modulus increased with the increasing post-annealing temperature.Thus,the fabricated membranes with superior mechanical strength can have potential applications such as in photocatalysis,filtering,and supporting substrates. | Xingyue Zhao Xiaochong Zhao Jianbao Li Xiangyun Deng Hong Lin | 2014 | Chinese Science Bulletin2014，59，13： | 0 |
| 13 | Effects of Addition of Amino Acids or Soybean Phospholipid in Diet on Slaughter Performance and Meat Quality of Pigs显示文摘[Objectives]The study aims to discuss the effects of addition of arginine and glutamic acid or soybean phospholipid,vitamin E and yeast selenium in diet on the slaughter performance and meat quality of long(white)×large(York)binary hybrid pigs.[Methods]27 long×large castrated hybrid boars with the body weight of(54.4±0.15)kg were randomly divided into 3 groups,with 3 replicates per group and 3 pigs per replicate.Group A was the control group,in which the pigs were fed basal diet;in group B,0.8%arginine and 0.60%glutamate were added to the basal diet;in group C,75 g of soybean phospholipid,20 g of vitamin E and 8 g of yeast selenium were added to every 100 kg of the basal diet.The trial period was 60 d.After the experiment was ended,one test pig with similar body weight was selected from each replicate for slaughter and meat determination.[Results]The average weight gain and eye muscle area of the pigs in group B were significantly higher than those in group C(P<0.05),and also showed an increasing trend compared with group A,but there was no statistically significant difference(P>0.05);there was no significant difference between group B or C and group A in the average weight gain and eye muscle area(P>0.05).There was no significant difference in other slaughter performance between the three groups(P>0.05).Besides,there was also no significant difference in the content of various amino acids,total amino acids and total umami amino acids between the three groups(P>0.05).The inosine content in the longissimus dorsi muscle and muscle cooking loss of binary hybrid pigs in group C were significantly better than those in group B(P<0.05),and also had a tendency to be better than those in group A,but there was no significant difference(P>0.05);there was no significant difference between group B or C and group A in the inosine content and muscle cooking loss of the pigs(P>0.05).In addition,there was no significant difference in other meat traits and chemical composition of the longissimus dorsi muscle between group B or C and group A(P>0.05).[Conclusions]The addition of arginine and glutamic acid or soybean phospholipid,vitamin E and yeast selenium in diet had no significant effect on the growth rate,slaughter performance and meat traits of long×large binary hybrid pigs. | Sicong LUO Shaobo LI Xiangyun HU Min CHEN Lingxiu GAN Tingju HUANG Wenjie LU Junxiang HUANG Haimei DENG Jiahuang YANG Cui YANG Xiuliang LI | 2023 | Asian Agricultural Research2023，15，4： | 0 |
| 14 | The Discovery of Deep High-Resistivity Block and Inadequately Consolidated Magma Chambers in Gaoligongshan Oblique Collisional Orogen and its Tectonic Implications显示文摘Objective The Gaoligongshan oblique collisional orogen is located in the southern section of the Hengduan Mountains,and belongs to one of the main Late Yanshanian-Himalayan oblique collisional orogens in the Sanjiang area.Many researchers have studied the geology,geochemistry and geophysics of this region,and many research achievements have been obtained from deep geophysical exploration of the region,especially using the magnetotelluric(MT)sounding technique.However,detailed | YU Nian WANG Xuben HU Xiangyun LI Dewei DENG Fangjin CAI Xuelin | 2017 | Acta Geologica Sinica(English Edition)2017，91，3： | 0 |
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