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| 1 | Multislice CT angiography in coronary artery disease: Technical developments, radiation dose and diagnostic value显示文摘Multislice computed tomography (CT) angiography has been increasingly used in the detection and diagnosis of coronary artery disease because of its rapid technical evolution from the early generation of 4-slice CT scanners to the latest models such as 64-slice, 256-slice and 320-slice CT scanners. Technical developments of multislice CT imaging enable improved diagnostic value in the detection of coronary artery disease, and this indicates that multislice CT can be used as a reliable lessinvasive alternative to invasive coronary angiography in selected patients. In addition, multislice CT angiography has played a significant role in the prediction of disease progression and cardiac events. Despite promising results reported in the literature, multislice CT has the disadvantage of having a high radiation dose which could contribute to the radiation-induced malignancy. A variety of strategies have been currently undertaken to reduce the radiation dose associated with multislice CT coronary angiography while in the meantime acquiring diagnostic images. In this article, the author will review the technical developments, radiation dose associated with multislice CT coronary angiography, and strategies to reduce radiation dose. The diagnostic and prognostic value of multislice CT angiography in coronary artery disease is briefly discussed, and future directions of multislice CT angiography in the diagnosis of coronary artery disease will also be highlighted. | Zhonghua Sun, Discipline of Medical Imaging, Department of Imaging and Applied Physics, Curtin University of Technology, Perth, Western Australia 6845, Australia | 2010 | World Journal of Cardiology2010，2，10： | 19 |
| 2 | Characteristics of Clostridium difficile infection in patients hospitalized with myelodysplastic syndrome or acute myelogenous leukemia显示文摘AIM To evaluate factors associated with Clostridium difficile infection (CDI) and outcomes of CDI in the myelodysplastic syndrome(MDS) and acute myeloid leukemia (AML) population.METHODS After IRB approval,all MDS/AML patients hospitalized at the University of Maryland Greenebaum Comprehensive Cancer Center between August 2011 and December 2013 were identified.Medical charts were reviewed for demographics,clinical information,development of CDI,complications of CDI,and mortality.Patients with CDI,defined as having a positive stool PCR done for clinical suspicion of CDI,were compared to those without CDI in order to identify predictors of disease.A t-test was used for comparison of continuous variables and chisquare or Fisher's exact tests were used for categorical variables,as appropriate.RESULTS Two hundred and twenty-three patients (60.1% male,mean age 61.3 years,13% MDS,87% AML) had 594 unique hospitalizations during the study period.Thirtyfour patients (15.2%) were diagnosed with CDI.Factors significantly associated with CDI included lower albumin at time of hospitalization (P < 0.0001),prior diagnosis of CDI (P < 0.0001),receipt of cytarabine-based chemotherapy (P = 0.015),total days of neutropenia (P = 0.014),and total days of hospitalization (P = 0.005).Gender (P = 0.10),age (P = 0.77),proton-pump inhibitor use (P = 0.73),receipt of antibiotics (P = 0.66),and receipt of DNA hypomethylating agent-based chemotherapy (P = 0.92) were not significantly associated with CDI.CONCLUSION CDI is common in the MDS/AML population.Factors significantly associated with CDI in this population include low albumin,prior CDI,use of cytarabine-based chemotherapy,and prolonged neutropenia.In this study,we have identified a subset of patients in which prophylaxis studies could be targeted. | Kamini Shah Bryan F Curtin Christopher Chu Daniel Hwang Mark H Flasar Erik von Rosenvinge | 2017 | World Journal of Clinical Oncology2017，8，5： | 3 |
| 3 | Effects of acidity on mineralization: pH-dependence of organic matter mineralization in weakly acidic soils显示文摘 | Denis Curtin C.A. Campbell Abdul Jalil | 1997 | Soil Biology and Biochemistry1997，，1： | 2 |
| 4 | Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders显示文摘 | E Joanna Baxter Linda M Scott Peter J Campbell Clare East Nasios Fourouclas Soheila Swanton George S Vassiliou Anthony J Bench Elaine M Boyd Natasha Curtin Mike A Scott Wendy N Erber Anthony R Green | 2005 | The Lancet . 2005 (9464)2005，，： | 2 |
| 5 | Characteristics of Missed or Interval Colorectal Cancer and Patient Survival: A Population-Based Study显示文摘 | N. Jewel Samadder Karen Curtin Thérèse M.F. Tuohy Lisa Pappas Ken Boucher Dawn Provenzale Kerry G. Rowe Geraldine P. Mineau Ken Smith Richard Pimentel Anne C. Kirchhoff Randall W. Burt | 2014 | Gastroenterology2014，，4： | 2 |
| 6 | 提高葡萄酒品质的有效途径(Ⅰ)——酒精发酵最重要的影响因素和保障策略显示文摘葡萄酒的感官品质取决于葡萄品种、酵母菌种、酿酒单宁、橡木制品等因素之间的相互作用,酿造工艺以及陈酿老熟阶段的生物化学变化。本文主要研究在酒精发酵过程中,如何选择酵母菌种以及如何进行酒精发酵的科学管理,以帮助酿酒师酿造出消费者青睐的高品质葡萄酒。 | 郭永亮 杜玉斌 Chris Curtin Ellie King | 2009 | 中外葡萄与葡萄酒2009，，3： | 2 |
| 7 | Association of total choles- teroL/high -density lipoprotein cholesterol ratio with proximal coro- nary atherosclerosis detected by multislice computed tomography 显示文摘 | Nair D Carrigan TP Curtin RJ | 2009 | Prey Cardiol2009，12，1： | 1 |
| 8 | Relationship of Ki-ms mutations in colon cancers to tumor location, stage, and survival : a population - based study 显示文摘 | Samowitz WS Curtin K Schaffer D | 2000 | Cancer Epide- miol Biomarkers Prey2000，9，： | 1 |
| 9 | The value of the tip-apex distance in predicting failure of fixation of peritrochanteric fractures of the hip显示文摘 | Baumgaertner MR Curtin SL Lindskog DM | 1995 | J Bone Joint Surg [Am]1995，77，7： | 1 |
| 10 | Early cleft palate repair and speech outcome显示文摘 | Dorf D Curtin JW | 1982 | Plast Reconstr Surg1982，70，1： | 1 |
| 11 | Diet, activity, and lifestyle associations with p53 mutations in colon tumors 显示文摘 | Slattery ML Curtin K Ma K | 2002 | Cancer Epidemiol Biomark Prey2002，11，： | 1 |
| 12 | Design a Direct 6-GHz Local Oscillator with a Wideband Integer-N PLL synthesizer显示文摘 | Mike Curtin | 1999 | Analog Dialogue1999，35，： | 1 |
| 13 | Comparison of CT and MR imaging in staging of neck metastases显示文摘 | Curtin HD Ishwaran H Mancuso AA | 1998 | Radiology1998，207，1： | 1 |
| 14 | Inflammatory and antiglioma effects of an adenovirus expressing human soluble Fms-like tyrosine kinase 3 ligand (hsFlt3L):treatment with hsFlt3L inhibits intracranial glioma progression 显示文摘 | Ali S Zirger JM Curtin JF | 2004 | Mol Ther2004，10，6： | 1 |
| 15 | Flt3L and TK gene therapy eradicate multifocal glioma in a syngeneic glioblastoma model 显示文摘 | KING G D MUHAMMAD A K CURTIN J F | 2008 | Neuro Oncol2008，10，1： | 1 |
| 16 | Posterior interosseous nerve:an alterna- tive to sural nerve biopsy 显示文摘 | Richards TA Curtin CM | 2010 | Plast Reconstr Surg2010，126，4： | 1 |
| 17 | Novel poly (ADP- ribose) polymerase- 1 inhibitor, AG14361, restores sensitivity to temozolomide in mismatch repair-deficient cells显示文摘 | CURTIN NJ WANG LZ YIAKOUVAKI A | 2004 | Clin Cancer Res2004，10，3： | 1 |
| 18 | Isolation of cancer stem cel s from adult glioblastoma multiforme显示文摘 | Yuan X Curtin J Xiong Y | | 0，，58： | 1 |
| 19 | Paclitaxel in the treatment of carcinosarcoma of the uterus: a gynecologic oncology group study显示文摘 | Curtin JP Blessing JA Soper JT | 2001 | Gynecol Oncol2001，83，2： | 1 |
| 20 | The catalytic oxidation of ammonia: Influence of water and sulfur on selectivity to nitrogen over promoted copper oxide/alumina catalysts显示文摘 | Curtin T Regan F O Deconinck C | 2000 | Catal Today2000，55，2： | 1 |
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