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| 1 | Switches in expression of Plasmodium falciparum var genes correlated with changes in antigenic and cytoadherent phenotypes of infected erythrocytes 显示文摘 | Smith JD Chitnis CE Craig AG | 1995 | Cell1995,82,1: | 1 |
| 2 | Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes 显示文摘 | Smith JD Chitnis CE Craig AG et ol | 1995 | Cell1995,82,1: | 1 |
| 3 | Multiple fertile queens in colonies of the red imported fire ant, Solenopsis invicta 显示文摘 | Glancey BM Craig CH Stringer CE | 1973 | J Ga Entomol Soc1973,8,: | 1 |
| 4 | Outcomes research in oncology: History, conceptual framework, and trends in the literature显示文摘 | Stephanie JL Craig CE Jane CW | 2000 | J National Cancer Institute2000,92,3: | 1 |
| 5 | Improving diabetic and hypertensive retinopathy with a medical food containing L-methylfolate: a preliminary report显示文摘Background:Homocysteine and vitamin D may play a role in the development of diabetic and hypertensive retinopathy in patients with diabetes mellitus(DM)and hypertension.Supplementing food with L-methylfolate and vitamin D theoretically may improve diabetic and hypertensive retinopathy,however,the outcome of these nutritional approaches has not been fully examined.A retrospective case review was done of cases of retinopathy reversal in patients on Ocufolin^(TM) and a similar nonprescription multivitamin,Eyefolate^(TM).In this study,they were administered L-methylfolate(2.7 mg and 3.0 mg,respectively)and vitamin D3(4500 IU each).These dosages are significantly above the RDA but well below levels associated with toxicity.Case presentation:Seven patients had nonproliferative diabetic retinopathy(NPDR)and some of them had hypertension.One patient had only hypertensive retinopathy.All patients were instructed to take Ocufolin^(TM)medical food as a food supplement.Baseline genetic testing for MTHFR polymorphisms was conducted.Fundus photography was used to document the fundus condition of the enrolled eyes in 8 NPDR patients at the initial and follow-up visits.Microaneurysms(MA)and exudates were observed to be improved in some trial patients.All subjects had one or more MTHFR polymorphisms.All had diabetic retinopathy,hypertensive retinopathy,or both.MAs were resolved,and exudates were decreased in 8/8 cases after taking the medical food.Retinal edema was found in 2/8 cases and improved or resolved in both cases after taking the medical food or the supplement.The best corrected visual activity was stable or improved in 8/8 cases.Conclusion:We report a series of diabetic and hypertensive retinopathy cases with MTHFR polymorphisms and the improvement of retinal microvasculature(mainly MAs)in serial fundus photography after taking a medical food or supplement containing L-methylfolate and vitamin D.It appears that the use of nutritional supplements and medical foods containing L-methylfolate and vitamin D may be effective in facilitating the improvement of diabetic and hypertensive retinopathy. | Jianhua Wang Craig Brown Ce Shi Justin Townsend Giovana Rosa Gameiro Peng Wang Hong Jiang | 2019 | Eye and Vision2019,6,1: | 1 |
| 6 | DNA barcoding is no substitute for taxonomy 显示文摘 | Mahe CE Craig H | 2005 | Nature2005,434,: | 1 |
| 7 | Mitoehondrial DNA mutaions in individuals occupationally exposed to ionizing radiation显示文摘 | Craig SW Kevin CE Janet TC | 2006 | Radiat Res2006,165,2: | 1 |
| 8 | The rising incidence of childhood type 1 diabetes in New South Wales,1990-2002显示文摘 | Taplin CE Craig ME Lloyd M | | 0,,: | 1 |
| 9 | Switches in expression of Plasmodiumfalciparum var genes correlate with changes in anti- genic and cytoadherent phenotypes of infected erythrocytes 显示文摘 | Smith JD Chitnis CE Craig AG | 1995 | Cell1995,82,1: | 1 |
| 10 | Switches in expression of Plasmodium falciparum var genes correlated with changes in antigenic and cytoadherent phenotypes of infected erythrocytes 显示文摘 | Smith JD Chitnis CE Craig AG | 1995 | Cell1995,82,1: | 1 |
| 11 | Prognostic factors following curative resection for pancreatic adenocarcinoma显示文摘 | Michael WC Craig CE | 2003 | Ann Surg2003,237,1: | 1 |
| 12 | The histopathology of regeneration in massive hepatic necrosis显示文摘 | Craig CE Quaglia A Selden C | 2004 | Semin Liver Dis2004,24,: | 1 |
| 13 | Significant antenatal factors in the development of lumbar spinal stenosis显示文摘 | Porter RW Craig CE | 1997 | Spine1997,22,18: | 1 |
| 14 | Mitochondrial DNA mutaions in individuals occupationally exposed to ionizing radiation显示文摘 | Craig SW Kevin CE Janet TC | 2006 | Radiat Res2006,165,2: | 1 |
| 15 | Switches in expression of Plasmodium falciparum vat genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes显示文摘 | Smith JD Chitnis CE Craig AG | 1995 | Cell1995,82,1: | 1 |
| 16 | Switches in expression ofPlasmodium falciparum var genes correlate with changes in anti-genic and cytoadherent phenotypes of infected erythrocytes显示文摘 | Smith JD Chitnis CE Craig AG | 1995 | Cell1995,82,: | 1 |
| 17 | Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes显示文摘 | Chitnis CE Craig AG | 1995 | Cell1995,82,1: | 1 |
| 18 | Nutritional and medical food therapies for diabetic retinopathy显示文摘Diabetic retinopathy(DR)is a form of microangiopathy.Reducing oxidative stress in the mitochondria and cell membranes decreases ischemic injury and end-organ damage to the retina.New approaches are needed,which reduce the risk and improve the outcomes of DR while complementing current therapeutic approaches.Homocysteine(Hcy)elevation and oxidative stress are potential therapeutic targets in DR.Common genetic polymorphisms such as those of methylenetetrahydrofolate reductase(MTHFR),increase Hcy and DR risk and severity.Patients with DR have high incidences of deficiencies of crucial vitamins,minerals,and related compounds,which also lead to elevation of Hcy and oxidative stress.Addressing the effects of the MTHFR polymorphism and addressing comorbid deficiencies and insufficiencies reduce the impact and severity of the disease.This approach provides safe and simple strategies that support conventional care and improve outcomes.Suboptimal vitamin co-factor availability also impairs the release of neurotrophic and neuroprotective growth factors.Collectively,this accounts for variability in presentation and response of DR to conventional therapy.Fortunately,there are straightforward recommendations for addressing these issues and supporting traditional treatment plans.We have reviewed the literature for nutritional interventions that support conventional therapies to reduce disease risk and severity.Optimal combinations of vitamins B1,B2,B6,L-methylfolate,methylcobalamin(B12),C,D,natural vitamin E complex,lutein,zeaxanthin,alpha-lipoic acid,and n-acetylcysteine are identified for protecting the retina and choroid.Certain medical foods have been successfully used as therapy for retinopathy.Recommendations based on this review and our clinical experience are developed for clinicians to use to support conventional therapy for DR.DR from both type 1 diabetes mellitus(T1DM)and type 2 diabetes mellitus(T2DM)have similar retinal findings and responses to nutritional therapies. | Ce Shi Peng Wang Shriya Airen Craig Brown Zhiping Liu Justin H.Townsend Jianhua Wang Hong Jiang | 2020 | Eye and Vision2020,7,1: | 1 |
| 19 | Nutritional and medical food therapies for diabetic retinopathy显示文摘Diabetic retinopathy(DR)is a form of microangiopathy.Reducing oxidative stress in the mitochondria and cell membranes decreases ischemic injury and end-organ damage to the retina.New approaches are needed,which reduce the risk and improve the outcomes of DR while complementing current therapeutic approaches.Homocysteine(Hcy)elevation and oxidative stress are potential therapeutic targets in DR.Common genetic polymorphisms such as those of methylenetetrahydrofolate reductase(MTHFR),increase Hcy and DR risk and severity.Patients with DR have high incidences of deficiencies of crucial vitamins,minerals,and related compounds,which also lead to elevation of Hcy and oxidative stress.Addressing the effects of the MTHFR polymorphism and addressing comorbid deficiencies and insufficiencies reduce the impact and severity of the disease.This approach provides safe and simple strategies that support conventional care and improve outcomes.Suboptimal vitamin cofactor availability also impairs the release of neurotrophic and neuroprotective growth factors.Collectively,this accounts for variability in presentation and response of DR to conventional therapy.Fortunately,there are straightforward recommendations for addressing these issues and supporting traditional treatment plans.We have reviewed the literature for nutritional interventions that support conventional therapies to reduce disease risk and severity.Optimal combinations of vitamins B1,B2,B6,L-methylfolate,methylcobalamin(B12),C,D,natural vitamin E complex,lutein,zeaxanthin,alpha-lipoic acid,and n-acetylcysteine are identified for protecting the retina and choroid.Certain medical foods have been successfully used as therapy for retinopathy.Recommendations based on this review and our clinical experience are developed for clinicians to use to support conventional therapy for DR.DR from both type 1 diabetes mellitus(T1DM)and type 2 diabetes mellitus(T2DM)have similar retinal findings and responses to nutritional therapies. | Ce Shi Peng Wang Shriya Airen Craig Brown Zhiping Liu Justin HTownsend Jianhua Wang Hong Jiang | 2022 | Eye and Vision2022,8,6: | 0 |