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| 1 | Role of radiation therapy in gastric adenocarcinoma显示文摘在有在美国的胃的癌症的病人的结果仍然保持令人失望,与约 23% 的五年的全面幸存率。本地人地区性的控制追随者外科的给定的高率,一个强壮的基本原理为辅助放射治疗的使用存在。使随机化的审判与辅助放射疗法显示出优异本地控制并且与辅助 chemoradiation 改进全面幸存。在由一位富有经验的外科医生经历了 D2 淋巴节点解剖的病人的辅助 chemoradiation 的利益不被知道,并且除了辅助化疗的辅助放射治疗的利益继续定义。在 unresectable 疾病, chemoradiation 在病人的一个小数字允许长期的幸存并且提供有效减轻。大多数试用独自与化疗或放射治疗相比显示出一个好处到联合形式治疗。使用外科手术前, intra 起作用, 3D 保角,并且在胃的癌症的调制放射治疗进一步正在答应,但是要求的紧张学习。当前的文章在能的将切除的治疗考察放射治疗的角色,集中于在美国的当前的建议并且 unresectable 胃的癌。 | Lisa Hazard John O'Connor Courtney Scaife | 2006 | World Journal of Gastroenterology2006，12，10： | 15 |
| 2 | 脑性瘫痪儿童的康复治疗:神经生理学方法与引导式教育方法显示文摘 | 魏国荣 O’connor | 2000 | 现代康复2000，4，10： | 12 |
| 3 | 中国上市公司业绩与总经理变更分析显示文摘本文研究了上市公司业绩与总经理的强制性变更和正常性变更的关系。研究结果显示,强制性总经理变更作为最极端的约束手段能够约束业绩差的总经理;差的业绩并不是导致总经理变更的原因。无论是强制性还是正常性总经理变更都对公司的业绩没有显著的影响,也就是说,总经理变更,特别是强制性总经理变更不能达到促进公司业绩提高的目的。 | 皮莉莉 Julian Lowe Christine O'Connor | 2005 | 甘肃社会科学2005，，3： | 9 |
| 4 | 非诺贝特治疗与2型糖尿病患者长期心血管病风险的关系显示文摘2型糖尿病患者心血管病风险高,部分原因在于高三酰甘油和低高密度脂蛋白胆固醇血症。而在他汀类药物治疗基础上,加强降低三酰甘油治疗,能否降低这种风险尚不清楚。该研究的目的是在使用他汀类药物治疗的2型糖尿病患者中,确定非诺贝特能否降低心血管病风险。 | 刘莉 叶鹏 Elam MB Ginsberg HN Lovato LC Corson M Largay J Leiter LA Lopez C O'Connor PJ Sweeney ME Weiss D Friedewald WT Buse JB Gerstein HC Probstfield J Grimm R Ismail-Beigi F Goff DC Jr Fleg JL Rosenberg Y Byington RP ACCORDION study investigators | 2017 | 中华高血压杂志2017，25，6： | 7 |
| 5 | Computed tomography and patient risk:Facts,perceptions and uncertainties显示文摘Since its introduction in the 1970s, computed tomography(CT) has revolutionized diagnostic decision-making. One of the major concerns associated with the widespread use of CT is the associated increased radiation exposure incurred by patients. The link between ionizing radiation and the subsequent development of neoplasia has been largely based on extrapolating data from studies of survivors of the atomic bombs dropped in Japan in 1945 and on assessments of the increased relative risk of neoplasia in those occupationally exposed to radiation within the nuclear industry. However, the association between exposure to low-dose radiation from diagnostic imaging examinations and oncogenesis remains unclear. With improved technology, significant advances have already been achieved with regards to radiation dose reduction. There are several dose optimization strategies available that may be readily employed including omitting unnecessary images at the ends of acquired series, minimizing the number of phases acquired, and the use of automated exposure control as opposed to fixed tube current techniques. In addition, new image reconstruction techniques that reduce radiation dose have been developed in recent years with promising results. These techniques use iterative reconstruction algorithms to attain diagnostic quality images with reduced image noise at lower radiation doses. | Stephen P Power Fiachra Moloney Maria Twomey Karl James Owen J O'Connor Michael M Maher | 2016 | World Journal of Radiology2016，8，12： | 7 |
| 6 | 磨矿介质材质与捕收剂添加方式对某铜镍硫化矿浮选的影响显示文摘通过磨矿和浮选试验研究了低碳钢和不锈钢两种磨矿介质与捕收剂添加方式对某铜镍硫化矿(Nkomati矿)浮选的影响。试验研究使用实验室用圆筒形棒磨机和机械搅拌式挂槽浮选机完成,通过浮选水回收率、精矿产率和有用矿物回收率分析了磨矿介质和捕收剂添加方式对铜镍硫化物浮选行为的影响。研究中对矿浆pH值、氧化还原电位(Eh)和溶解氧(Do)等溶液化学性质进行了测定,以考察磨矿介质及捕收剂添加方式对溶液化学性质的影响。磨矿介质对Nkomati矿的矿浆溶液化学性质和浮选行为具有显著影响,经低碳钢磨矿后,具有较高的铜、镍和磁黄铁矿回收率,EDTA可浸出铁的含量更高,Do值更低。不同磨矿介质磨矿条件下,捕收剂添加方式对铜镍矿浮选的影响规律不同,低碳钢磨矿时,捕收剂添加在浮选槽中的铜回收率较高;不锈钢磨矿时,捕收剂添加在磨机中的铜和镍的回收率较高。 | 宋振国 K Corin J G Wiese C T O'Connor | 2017 | 矿产保护与利用2017，37，6： | 6 |
| 7 | Gastroenterologist perceptions of faecal microbiota transplantation显示文摘AIM: To explore gastroenterologist perceptions towards and experience with faecal microbiota transplantation(FMT).METHODS: A questionnaire survey consisting of 17 questions was created to assess gastroenterologists' attitude towards and experience with FMT. This was anonymously distributed in hard copy format amongst attendees at gastroenterology meetings in Australia between October 2013 and April 2014. Basic descriptive statistical analyses were performed.RESULTS: Fifty-two clinicians participated. Twenty one percent had previously referred patients for FMT,8% more than once. Ninety percent would refer patients with Clostridium difficile infection(CDI) for FMT if easily available,37% for ulcerative colitis,13% for Crohn's disease and 6% for irritable bowel syndrome. Six percent would not refer any indication,including recurrent CDI. Eighty-six percent would enroll patients in FMT clinical trials. Thirty-seven percent considered the optimal mode of FMT administration transcolonoscopic,17% nasoduodenal,13% enema and 8% oral capsule. The greatest concerns regarding FMT were: 42% lack of evidence,12% infection risk,10% non infectious adverse effects/lack of safety data,10% aesthetic,10% lack of efficacy,4% disease exacerbation,and 2% inappropriate use; 6% had no concerns. Seventy seven percent believed there is a lack of accessibility while 52% had an interest in learning how to provide FMT. Only 6% offered FMT at their institution.CONCLUSION: Despite general enthusiasm,most gastroenterologists have limited experience with,or access to,FMT. The greatest concerns were lack of supportive evidence and safety issues. However a significant proportion would refer indications other than CDI for FMT despite insufficient evidence. These data provide guidance on where education and training are required. | Sudarshan Paramsothy Alissa J Walsh Thomas Borody Douglas Samuel Johan van den Bogaerde Rupert WL Leong Susan Connor Watson Ng Hazel M Mitchell Nadeem O Kaakoush Michael A Kamm | 2015 | World Journal of Gastroenterology2015，21，38： | 5 |
| 8 | New Species of Enantiornithes(Aves:Ornithothoraces) from the Qiaotou Formation in Northern Hebei,China显示文摘我们从北 Hebei 的更低的白垩纪 Qiaotou 形成在 enantiornithine 鸟的新种上报导,中国。新 taxon, Shenqiornis mengi 情报。et sp。nov,拥有几 enantiornithine synapomorphies,但是从另外的已知的种类是唯一的。标本有关于 enantiornithine 揭示新信息的一个保存得很好的颅骨头部的形态学。新 taxon 拥有一大与显示某 enantiornithines 可能有的一个长尖端细的颧骨的过程眼窝后部一充分 diapsid 颅骨,在 Confuciusornis。标本的牙齿形态学是唯一的并且多半在 Enantiornithes 以内代表以前未知的营养的专门化。 | WANG Xuri Jingmai K. O'CONNOR ZHAO Bo Luis M. CHIAPPE GAO Chunling CHENG Xiaodong | 2010 | Acta Geologica Sinica(English Edition)2010，84，2： | 5 |
| 9 | Helicobacter pylori resistance rates for levofloxacin, tetracycline and rifabutin among Irish isolates at a reference centre显示文摘 | A. O’Connor I. Taneike A. Nami N. Fitzgerald B. Ryan N. Breslin H. O’Connor D. McNamara P. Murphy C. O’Morain | 2013 | Irish Journal of Medical Science2013，，4： | 4 |
| 10 | Brain-derived neurotrophic factor and inflammation in depression:Pathogenic partners in crime?显示文摘Major depressive disorder is a debilitating disorder affecting millions of people each year.Brain-derived neurotrophic factor(BDNF)and inflammation are two prominent biologic risk factors in the pathogenesis of depression that have received considerable attention.Many clinical and animal studies have highlighted associations between low levels of BDNF or high levels of inflammatory markers and the development of behavioral symptoms of depression.However,less is known about potential interaction between BDNF and inflammation,particularly within the central nervous system.Emerging evidence suggests that there is bidirectional regulation between these factors with important implications for the development of depressive symptoms and antidepressant response.Elevated levels of inflammatory mediators have been shown to reduce expression of BDNF,and BDNF may play an important negative regulatory role on inflammation within the brain.Understanding this interaction more fully within the context of neuropsychiatric disease is important for both developing a fuller understanding of biological pathogenesis of depression and for identifying novel therapeutic opportunities.Here we review these two prominent risk factors for depression with a particular focus on pathogenic implications of their interaction. | Grace A Porter Jason C O’Connor | 2022 | World Journal of Psychiatry2022，12，1： | 4 |
| 11 | Chronic pancreatitis:A diagnostic dilemma显示文摘Typical clinical symptoms of chronic pancreatitis are vague and non-specific and therefore diagnostic tests are required, none of which provide absolute diagnostic certainly, especially in the early stages of disease. Recently-published guidelines bring much needed structure to the diagnostic work-up of patients with suspected chronic pancreatitis. In addition, novel diagnostic modalities bring promise for the future. The assessment and diagnosis of pancreatic exocrine insufficiency remains challenging and this review contests the accepted perspective that steatorrhea only occurs with > 90% destruction of the gland. | Sinead N Duggan Hazel M NíChonchubhair Oladapo Lawal Donal B O’Connor Kevin C Conlon | 2016 | World Journal of Gastroenterology2016，22，7： | 4 |
| 12 | 老年人处方遗漏筛查工具第2版(中文版)显示文摘近年来我国老年人口数量迅速增加,2013年老年人口突破2亿大关。老年人常伴有多种疾病且同时服用多种药物,容易出现药物相互作用和药物不良反应,所以老年人用药问题是医务人员关注的重点。老年人不适当用药问题主要包括两个方面:老年人需要避免使用的药物和老年人需要使用而未使用的药物。 | Denis O'Mahony David O'Sullivan Stephen Byrne Marie Noelle O'Connor Cristin Ryan Paul Gallagher 侯凯旋 邢晓璇 闫素英 | 2017 | 药物不良反应杂志2017，19，5： | 4 |
| 13 | Dominance network structure across reproductive contexts in the cooperatively breeding cichlid fish Neolamprologus pulcher显示文摘 | Cody J. DEY Q.Y. Joanne TAN Constance M. O'CONNOR Adam R. REDDON J. Ryan CALDWELL Sigal BALSHINE | 2015 | Current Zoology2015，61，1： | 4 |
| 14 | 手术中知晓事件的新分级标准显示文摘背景有外显记忆的手术中知晓事件的发生率仅为1/1000—2/1000。因其较罕见,为了更好的了解手术中知晓事件及其后遗效直,需要对大批量的研究数据进行统计。因此,对其进行标准描述和表达将很有价值。方法本研究创建了一种新的手术中知晓事件评估标准:0级:未发生手术中知晓;1级:仅存在听觉感知;2级:感知触觉(比如手术操作、气管插管);3级:感知痛觉;4级:感知麻痹(比如感到不能活动、说话或呼吸);5级:感知麻痹及痛觉。患者主述有恐惧、焦虑、窒息、末日感、濒死感及其他相关显性描述,另行附加“D”(distress[痛苦、悲伤])。本研究回顾了15项详细提供手术中知晓报告信息的研究。来自3个研究并创建了该项分级标准的5位麻醉医生,各自独立的评估了这些病例。另外20名相关人员(麻醉主治医生、麻醉住院医生、麻醉护士、医学生及其辅助工作人员),虽未参与该分级标准的创建,但也独立对手术中知晓事件进行了评估。用Flwiss’s κ系数评估观察者之间的一致性。结果对151例确认发生手术中知晓事件的成年病例进行数据分析。基础评估1~5级中,总体κ系数为0.851(95%可信区间CI0.847~0.856)。包括附加情感障碍“D”的评估中,总体κ系数为0.779(95%可信区间CI 0.776~0.783)。结论本研究创建了新的手术中知晓事件评估标准,在评估者间具有近乎完美的一致性,这将有助于手术中知晓事件的研究。 | George A. Mashour Roy K. Esaki Kevin K. Tremper David B. Glick Michael O'Connor Michael S. Avidan 潘鹏(译) 李文志(校) | 2009 | 麻醉与镇痛2009，，6： | 3 |
| 15 | 未控制高血压患者进行家庭血压监测与药剂师管理后的心血管事件及费用显示文摘未控制高血压是心血管病的主要病因。在16家初级保健诊所进行的整群随机试验结果表明:12个月的远程家庭血压监测与药剂师管理可较常规治疗24个月降压幅度更大。该文报道心血管事件(非致死性心肌梗死、非致死性脑卒中、心力衰竭住院、冠状动脉再血管化及心血管病死亡)与随访5年的花费。在远程干预组(TI组,n=228),10例患者发生15次心血管事件(5次心肌梗死、4次脑卒中、5次心力衰竭、1次心血管病死亡)。 | 赵狄(摘译) 刘莉(审校) Margolis KL Dehmer SP Sperl-Hillen J O’Connor PJ Asche SE Bergdall AR Green BB Nyboer RA Pawloski PA Trower NK Maciosek MV | 2020 | 中华高血压杂志2020，28，11： | 3 |
| 16 | 体质量状态变化与高血压发生的相关性显示文摘在美国近1/3的儿童和青少年是肥胖或超重的。虽然最近该比值保持稳定,但在过去40年中则呈快速上升的趋势。儿童肥胖与高血压显著相关。主要在初中和高中学生中进行的流行病学调查研究报道,高血压的发病率在0.8%~3.2%,而在肥胖学生中高血压发病率则〉10%。在大型的医疗保健系统门诊和小学儿童中进行的一项研究报道显示,正常体质量的儿童高血压总发病率为0.3%~0.9%,肥胖儿童为1.0%~9.2%。 | Parker ED Sinaiko AR Kharbanda EO Margolis KL Daley MF Trower NK Sherwood NE Greenspan LC Lo JC Magid DJ o'connor pj | 2016 | 中华高血压杂志2016，24，6： | 3 |
| 17 | Exceptional preservation of soft tissue in a new specimen of Eoconfuciusornis and its biological implications显示文摘We report on an exceptional specimen of Eoconfuciusornis preserving rare soft-tissue traces of the ovary and wing. Ovarian follicles preserve a greater hierarchy than observed in Jeholornis and enantiornithines,suggesting confuciusornithiforms evolved higher rates of yolk deposition in parallel with the neornithine lineage. The preserved soft tissues of the wing indicate the presence of a propatagium and postpatagium,whereas an alular patagium is absent. Preserved remnants of the internal support network of the propatagium bear remarkable similarity to that of living birds. Soft tissue suggests the confuciusornithiform propatagium could maintain a cambered profile and generate lift. The feathers of the wing preserve remnants of their original patterning; however, this is not strongly reflected by observable differences under scanning electron microscopy(SEM). The tail plumage lacks elongate rectrices, suggesting that the earliest known confuciusornithiforms were sexually dimorphic in their plumage. | Xiaoting Zheng Jingmai K. O'Connor Xiaoli Wang Yanhong Pan Yan Wang Min Wang Zhonghe Zhou | 2017 | National Science Review2017，4，3： | 3 |
| 18 | Cost benefit analysis of the use of tranexamic acid in primary lower limb arthroplasty: A retrospective cohort study显示文摘AIM: To examine the cost benefit conferred by the perioperative administration of intravenous tranexamic acid(TXA) in lower limb arthroplasty.METHODS: This study evaluates the use of TXA in 200 consecutive lower limb arthroplasties performed in a single surgeon series. The initial 100 patients(control group) underwent surgery without perioperative administration of TXA while the subsequent 100 patients(TXA group) all received 1 g TXA at the time of induction of anaesthesia. Pre- and post-operative haemoglobin, platelet count, haematocrit, the use of blood product post-operatively, length of stay were examined. A financial analysis of both groups was then undertaken. RESULTS: The mean age of patients in both groups was 63 ± 13 years. There were no significant differences between groups in terms of gender(P = 0.47), proportion of total hip replacement to total knee replacement(P = 0.25) or pre-operative haemoglobin(P = 0.43). In the control group, the transfusion rate was 22%. In the TXA group, the transfusion rate dropped to 2%(P < 0.001). The mean post-operative haemoglobin was 10.82 ± 1.55g/dL in the control group vs 11.33 ± 1.27 g/dL in the TXA group(P = 0.01). The total cost of transfused blood products was €11055 and €603 respectively. The mean length of stay in the control group was 6.53 ± 5.93 d vs 5.47 ± 4.26 d in the TXA group(P = 0.15) leading to an estimated financial saving of €114586. There was one pulmonary embolus in the control group and one deep venous thrombosis in the TXA group.CONCLUSION: Intravenous TXA reduces blood loss in lower limb arthroplasty. This leads to lower transfusion rates, shorter length of stay in hospital and significant financial savings. | Niall P McGoldrick Eabhann M O'Connor Nikos Davarinos Rose Galvin John F Quinlan | 2015 | World Journal of Orthopedics2015，6，11： | 3 |
| 19 | Omega-3 supplementation and non-alcoholic fatty liver disease: A systematic review and meta-analysis显示文摘 | Helen M. Parker Nathan A. Johnson Catriona A. Burdon Jeffrey S. Cohn Helen T. O’Connor Jacob George | 2011 | Journal of Hepatology2011，，4： | 3 |
| 20 | 血管加压素拮抗剂Tolvaptan对院内心力衰竭患者的疗效:随机对照试验显示文摘背景:美国每年约有一百万人因慢性心力衰竭而入院,多数与充血性心力衰竭恶化有关。利尿剂是充血性心力衰竭的主要治疗手段,可导致电解质紊乱和肾功能恶化。与利尿剂不同,血管加压素拮抗剂tolvaptan在减少心力衰竭患者血容量的同时对电解质和肾功能无副作用。 | Mihai Gheorghiade Wendy A. Gattis Christopher M. O'Connor 范琰(译) 刘梅林(校) | 2005 | 美国医学会杂志(中文版)2005，24，4： | 3 |
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