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| 1 | Phosphorus oxoanion-intercalated layered double hydroxides for high-performance oxygen evolution显示文摘合理设计和为氧进化反应(OER ) 的有效、划算的电极的控制制造为探讨崭新的精力危机是批评的。有特定的夹层阴离子的镍铁分层的双氢氧化物(NiFe-LDHs )( 即磷酸盐,亚磷酸盐,和次磷酸盐) 被一个一起沉淀方法制作并且作为氧进化 electrocatalysts 调查了。磷 oxoanion 的置闰在一个碱的答案提高了 OER 活动;最佳的表演(即, 215 mV, 37.7 mV/dec 的一个小 Tafel 斜坡,和稳定的电气化学的行为的一个低发作潜力) 与设置次磷酸盐的 NiFe-LDH 催化剂被完成,在传统的设置碳酸盐的 NiFe-LDH 上的示威戏剧的改进以活动和耐久性。这提高的表演被归因于在设置的磷的 oxoanions 和分享边的瞬间 6 之间的相互作用(M = Ni, Fe ) 层,它修改表面 Ni 地点的电子结构。这个概念应该为更有效的基于 LDH 的氧进化 electrocatalysts 的设计是鼓舞人心的。 | Ma Luo Zhao Cai Cheng Wang Yongmin Bi Li Qian Yongchao Hao Li Li Yun Kuang Yaping Li Xiaodong Lei Ziyang HUO Wen Liu Hailiang Wang Xiaoming Sun Xue Duan | 2017 | Nano Research2017，10，5： | 12 |
| 2 | Epac and PKA: a tale of two intracellular cAMP receptors显示文摘调停营地的发信号小径在生理、病理学的条件下面调整大量的重要生物过程,包括糖尿病,心失败和癌症。在真核细胞的房间,营地的效果被二无所不在地表示的细胞内部的营地受体,经典蛋白质 kinase A (PKA )/cAMP-dependent 蛋白质 kinase 和营地(Epac ) 直接激活的最近发现的交换蛋白质调停 /cAMP-regulated guanine 核苷酸交换因素。象 PKA 一样, Epac 包含一个进化联盟者为察觉到细胞内部的秒送信人营地层次控制多样的生物函数充当一个分子的开关的保存营地绑定领域。营地受动器的二个家庭的存在为以一种空间、时间的方式表明小径的营地的更精确、综合的控制提供机制。象他们丰富,分发和本地化, Epac 和 PKA 可以独立地扮演, synergistically 收敛或在调整特定的细胞的功能反对对方的亲戚一样取决于特定的细胞的环境。 | Xiaodong Cheng Zhenyu Ji Tamara Tsalkova Fang Mei | 2008 | Acta Biochimica et Biophysica Sinica2008，40，7： | 10 |
| 3 | Dongbeititan dongi,the First Sauropod Dinosaur from the Lower Cretaceous Jehol Group of Western Liaoning Province,China显示文摘我们此处描述一条 sauropod 恐龙的头部的骨骼在西方的辽宁省的 Beipiao 区域从更低的白垩纪 Jehol 组恢复了的一根部分柱子,东北中国。它拥有的特征的一间套房,包括骆驼它的 presacral 元素,在背面的肋骨的近似结束的 pneumatocoels 的存在,和特别腿节的中间地偏斜的近似部分的晚内部的结构,决定性地建立标本的 titanosauriform 亲密关系。它在有不同于另外的 titanosauriforms 一 craniocaudally 伸长有摆平的 cranioventral 极端和一张长、光滑、稍微凸的王牌的鸟喙骨耻骨的平坦的边。它代表新税在上, Dongbeititan 盾 i 情报。et sp。nov。比较研究建议 Dongbeititan 是基础 titanosauriform,比 Euhelopus 导出,但是少些比 Gobititan 和 Jiutaisaurus 发源的更多, Fusuisaurus,和 Huanghetitan。Dongbeititan 表示第一条 sauropod 恐龙从西方的辽宁省的更低的白垩纪 Jehol 组报导了。 | WANG Xuri YOU Hailu MENG Qingjin GAO Chunling CHENG Xiaodong LIU Jinyuan | 2007 | Acta Geologica Sinica(English Edition)2007，81，6： | 9 |
| 4 | Paleomagnetic data from the Late Carboniferous-Late Permian rocks in eastern Tibet and their implications for tectonic evolution of the northern Qiangtang-Qamdo block显示文摘We report paleomagnetic results from the Late Carboniferous-Late Permian strata in eastern Tibet (China), and aim to clarify the tectonic and paleogeographic evolution of the northern Qiangtang-Qamdo block, which is the key to the study of plate boundary between the Gondwanaland and the Eurasia during the late Paleozoic. Two hundred and nineteen samples-including limestone, muddy siltstone, basalt, lava, and tuff-were collected at 24 sites in the Upper Carboniferous and Middle-Upper Permian successions. A systematic study of rock magnetism and paleomagnetism yields three reliable paleomagnetic pole positions. Both hematite and magnetite occurred in the Late Carboniferous limestone samples. The demagnetization curve shows a characteristic double-component, with the remanent magnetization (ChRM) exhibiting a positive polarity (negative inclination). In the Late Permian limestone, tuff, and basalt, magnetic information were recorded primarily in magnetite, although a small fraction of them was found in hematite in basalt. The demagnetization curve illustrates a double or single component, with the ChRM showing a negative polarity (positive inclination), which has passed the classic fold test successfully. The single polarity features of the ChRM directions of the Late Carboniferous and Middle-Late Permian rocks are respectively related to the Kiaman positive and reversed polarities under the stratigraphic coordinates. This, in turn, indicates that both ChRMs directions represent the original remanence directions. By comparison with the previously published paleomagnetic results from the late Paleozoic rocks in the northern Qiangtang Range, we suggest that: (1) Qamdo and northern Qiangtang block were independent of each other during the Late Carboniferous to the Early Permian periods. The north Lancangjiang ocean basin between the two blocks may have closed before the Middle Permian and been involved in the continent-continent collision stage in the Late Permian-Early Triassic periods. (2) The northern Qiangtang-Qamdo Block paleogeographically was situated at low to intermediate latitudes in the Southern Hemisphere in the Late Carboniferous-Late Permian periods, and began to displace northward in the Early Triassic, with an amount of more than 5000 km northward transport from its current location. | CHENG Xin WU HanNing DIAO ZongBao WANG HaiJun MA Lun ZHANG XiaoDong YANG Gang HONG JingJing JI WenHua LI RongShe CHEN ShouJian ZHAO ZhenMing | 2013 | Science China Earth Sciences2013，56，7： | 8 |
| 5 | Propofol inhibits inflammation and lipid peroxidation following cerebral ischemia/reperfusion in rabbits显示文摘The present study established a rabbit model of global cerebral ischemia using the 'six-vessel' method,which was reperfused after 30 minutes of ischemia.Rabbits received intravenous injection of propofol at 5 mg/kg prior to ischemia and 20 mg/kg per hour after ischemia until samples were prepared.Results revealed that propofol inhibited serum interleukin-8,endothelin-1 and malondialdehyde increases and promoted plasma superoxide dismutase activity after cerebral ischemia/reperfusion.In addition,cerebral cortex edema was attenuated with little neuronal nuclear degeneration and pyknosis with propofol treatment.The cross-sectional area of neuronal nuclei was,however,increased following propofol treatment.These findings suggested that propofol could improve anti-oxidant activity and inhibit synthesis of inflammatory factors to exert a protective effect on cerebral ischemia/reperfusion injury. | Xiaodong Wei Xing Wan Bo Zhao Jiabao Hou Min Liu Bangchang Cheng | 2012 | Neural Regeneration Research2012，7，11： | 8 |
| 6 | Formation mechanism of a smooth, defectfree surface of fused silica optics using rapid CO2 laser polishing显示文摘Surface defects introduced by conventional mechanical processing methods can induce irreversible damage and reduce the service life of optics applied in high-power lasers.Compared to mechanical processing,laser polishing with moving beam spot is a noncontact processing method,which is able to form a defect-free surface.This work aims to explore the mechanism of forming a smooth,defect-free fused silica surface by high-power density laser polishing with coupled multiple beams.The underlying mechanisms of laser polishing was revealed by numerical simulations and the theoretical results were verified by experiments.The simulated polishing depth and machined surface morphology were in close agreement with the experimental results.To obtain the optimized polishing quality,the effects of laser polishing parameters(e.g.overlap rate,pulse width and polishing times)on the polishing quality were experimentally investigated.It was found that the processing efficiency of fused silica materials by carbon dioxide(CO2)laser polishing could reach 8.68 mm2 s−1,and the surface roughness(Ra)was better than 25 nm.Besides,the cracks on pristine fused silica surfaces introduced by initial grinding process were completely removed by laser polishing to achieve a defect-free surface.The maximum laser polishing rate can reach 3.88μm s−1,much higher than that of the traditional mechanical polishing methods.The rapid CO2 laser polishing can effectively achieve smooth,defect-free surface,which is of great significance to improve the surface quality of fused silica optics applied in high-power laser facilities. | Linjie Zhao Jian Cheng Mingjun Chen Xiaodong Yuan Wei Liao Qi Liu Hao Yang Haijun Wang | 2019 | International Journal of Extreme Manufacturing2019，1，3： | 8 |
| 7 | Dog sciatic nerve gap repaired by artificial tissue nerve graft显示文摘The feasibility of repairing dog sciatic nerve damage by using a biodegradable artificial tissue nerve graft enriched with neuroregenerating factors is investigated. The artificial nerve graft was implanted to a 30 mm gap of the sciatic nerve damage in 7 dogs. The dogs with the same nerve damage that were repaired by interposition of the autologous nerve or were given no treatment served as control group 1 or 2, respectively. The observations include gross and morphological observations, immune reaction, electrophysiological examination, fluorescence tracing of the neuron formation and the number of the neurons at the experimental sites, etc. Results showed that 6 months after the implantation of the graft, the regenerated nerve repaired the damage of the sciatic nerve without occurrence of rejection and obvious inflammatory reaction in all 7 dogs, and the function of the sciatic nerve recovered with the nerve conduction velocity of (23.91±11.35)m/s. The regenerated neurons and the forming of axon could be observed under an electron microscope. This proves that artificial tissue nerve graft transplantation can bridge the damaged nerve ends and promote the nerve regeneration. | GU Xiaosong, ZHANG Peiyun, WANG Xiaodong, DING Fei, PENG Luping and CHENG Hongbing(Nantong Medical College, The Key Laboratory of Neuroregeneration of Jiangsu Province, Nantong 226001, China) | 2003 | Progress in Natural Science:Materials International2003，13，8： | 6 |
| 8 | New Species of Enantiornithes(Aves:Ornithothoraces) from the Qiaotou Formation in Northern Hebei,China显示文摘我们从北 Hebei 的更低的白垩纪 Qiaotou 形成在 enantiornithine 鸟的新种上报导,中国。新 taxon, Shenqiornis mengi 情报。et sp。nov,拥有几 enantiornithine synapomorphies,但是从另外的已知的种类是唯一的。标本有关于 enantiornithine 揭示新信息的一个保存得很好的颅骨头部的形态学。新 taxon 拥有一大与显示某 enantiornithines 可能有的一个长尖端细的颧骨的过程眼窝后部一充分 diapsid 颅骨,在 Confuciusornis。标本的牙齿形态学是唯一的并且多半在 Enantiornithes 以内代表以前未知的营养的专门化。 | WANG Xuri Jingmai K. O'CONNOR ZHAO Bo Luis M. CHIAPPE GAO Chunling CHENG Xiaodong | 2010 | Acta Geologica Sinica(English Edition)2010，84，2： | 5 |
| 9 | Diaphragm wall-soil-cap interaction in rectangular-closed-diaphragm-wall bridge foundations显示文摘Rectangular-closed-diaphragm-wall foundation is a new type of bridge foundation.Diaphragm wallsoil-cap interaction was studied using a model test.It was observed that the distribution of soil resistance under the cap is not homogeneous.The soil resistance in the corner under the cap is larger than that in the border;and that in the center is the smallest.The distribution of soil resistance under the cap will be more uniform,if the sectional area of soil core is enlarged within a certain range.Due to the existence of cap,there is a“weakening effect”in inner shaft resistance of the upper wall segments,and there is“enhancement effect”in the lower wall segments and in toe resistance.The load shearing percentage of soil resistance under the cap is 10%–20%.It is unreasonable to ignore the effects of the cap and the soil resistance under the cap in bearing capacity calculations. | Hua WEN Qiangong CHENG Fanchao MENG Xiaodong CHEN | 2009 | Frontiers of Structural and Civil Engineering2009，3，1： | 5 |
| 10 | Paleomagnetic results from Late Carboniferous to Early Permian rocks in the northern Qiangtang terrane, Tibet, China, and their tectonic implications显示文摘Results of a systematic paleomagnetic study are reported based on Late Carboniferous to Early Permian sedimentary rocks on the north slope of the Tanggula Mountains,in the northern Qiangtang terrane(NQT),Tibet,China.Data revealed that magnetic minerals in limestone samples from the Zarigen Formation(CP^z)are primarily composed of magnetite,while those in sandstone samples from the Nuoribagaribao Formation(Pnr)are dominated by hematite alone,or hematite and magnetite in combination.Progressive thermal,or alternating field,demagnetization allowed us to isolate a stable high temperature component(HTC)in 127 specimens from 16 sites which successfully passed the conglomerate test,consistent with primary remnance.The tilt-corrected mean direction for Late Carboniferous to Early Permian rocks in the northern Qiangtang terrane is D_s=30.2°,I_s=-40.9°,k_s=269.0,a_(95)=2.3°,N=16,which yields a corresponding paleomagnetic pole at 25.7°N,241.5°E(dp/dm=2.8°/1.7°),and a paleolatitude of 23.4°S.Our results,together with previously reported paleomagnetic data,indicate that:(1)the NQT in Tibet,China,was located at a low latitude in the southern hemisphere,and may have belonged to the northern margin of Gondwana during the Late Carboniferous to Early Permian;(2)the Paleo-Tethys Ocean was large during the Late Carboniferous to Early Permian,and(3)the NQT subsequently moved rapidly northwards,perhaps related to the fact that the Paleo-Tethys Ocean was rapidly contracting from the Late Permian to Late Triassic while the Bangong Lake-Nujiang Ocean,the northern branch of the Neo-Tethys Ocean,expanded rapidly during this time. | YANG XingFeng CHENG Xin ZHOU YaNan MA Lun ZHANG XiaoDong YAN ZhaoSheng PENG XiMing SU HaiLun WU HanNing | 2017 | Science China Earth Sciences2017，60，1： | 5 |
| 11 | Combining docking and comparative molecular similarity indices analysis (COMSIA) to predict estrogen activity and probe molecular mechanisms of estrogen activity for estrogen compounds显示文摘Estrogen compounds are suspected of disrupting endocrine functions by mimicking natural hormones, and such compounds may pose a serious threat to the health of humans and wildlife. Close attention has been paid to the prediction and molecular mechanisms of estrogen activity for estrogen compounds. In this article, estrogen receptor α subtype (ERα)–based comparative molecular similarity indices analysis (COMSIA) was performed on 44 estrogen compounds with structural diversity to find out the structural relationship with the activity and to predict the activity. The model with the significant correlation and the best predictive power (R2 = 0.965, Q2LOO = 0.599, R2pred = 0.825) was achieved. The COMSIA and docking results revealed the structural features for estrogen activity and key amino acid residues in binding pocket, and provided an insight into the interaction between the ligands and these amino acid residues. | YANG XuShu WANG XiaoDong JI Li LI Rong SUN Cheng WANG LianSheng | 2008 | Chinese Science Bulletin2008，53，23： | 4 |
| 12 | An analytical model for estimating soil temperature profiles on the Qinghai-Tibet Plateau of China显示文摘Soil temperature is a key variable in the control of underground hydro-thermal processes. To estimate soil temperature more accurately, this study proposed a solution method of the heat conduction equation of soil temperature(improved heat conduction model) by applying boundary conditions that incorporate the annual and diurnal variations of soil surface temperature and the temporal variation of daily temperature amplitude, as well as the temperature difference between two soil layers in the Tanggula observation site of the Qinghai-Tibet Plateau of China. We employed both the improved heat conduction model and the classical heat conduction model to fit soil temperature by using the 5 cm soil layer as the upper boundary for soil depth. The results indicated that the daily soil temperature amplitude can be better described by the sinusoidal function in the improved model, which then yielded more accurate soil temperature simulating effect at the depth of 5 cm. The simulated soil temperature values generated by the improved model and classical heat conduction model were then compared to the observed soil temperature values at different soil depths. Statistical analyses of the root mean square error(RMSE), the normalized standard error(NSEE) and the bias demonstrated that the improved model showed higher accuracy, and the average values of RMSE, bias and NSEE at the soil depth of 10–105 cm were 1.41°C, 1.15°C and 22.40%, respectively. These results indicated that the improved heat conduction model can better estimate soil temperature profiles compared to the traditional model. | HU Guojie ZHAO Lin WU Xiaodong LI Ren WU Tonghua XIE Changwei QIAO Yongping SHI Jianzong CHENG Guodong | 2016 | Journal of Arid Land2016，8，2： | 4 |
| 13 | The pleiotropic role of exchange protein directly activated by cAMP 1 (EPAC1) in cancer: implications for therapeutic intervention显示文摘多种的秒送信人腺苷 3,5-cyclic monophosphate (营地) 调整无数生物过程在下面生理并且 pathophysiological 条件。营地 1 直接激活的交换蛋白质(EPAC1 ) 调停由充当 guanine 核苷酸的营地的细胞内部的功能把因素换作像地岬的敲击小 GTPases。最近的研究建议 EPAC1 在 immunomodulation,癌症房间迁居 / 转移,和新陈代谢起重要作用。这些结果,结合了 EPAC 特定的小分子禁止者的成功的发展,为癌症治疗作为一个有希望的治疗学的目标识别 EPAC1。 | Muayad Almahariq Fang C. Mei Xiaodong Cheng | 2016 | Acta Biochimica et Biophysica Sinica2016，48，1： | 4 |
| 14 | Highly Dispersed Cobalt Nanoparticles Embedded in Nitrogen-Doped Graphitized Carbon for Fast and Durable Potassium Storage显示文摘Potassium-ion batteries(KIBs)have great potential for applications in large-scale energy storage devices.However,the larger radius of K+leads to sluggish kinetics and inferior cycling performance,severely restricting its practical applicability.Herein,we propose a rational strategy involving a Prussian blue analogue-derived graphitized carbon anode with fast and durable potassium storage capability,which is constructed by encapsulating cobalt nanoparticles in nitrogen-doped graphitized carbon(Co-NC).Both experimental and theoretical results show that N-doping effectively promotes the uniform dispersion of cobalt nanoparticles in the carbon matrix through Co-N bonds.Moreover,the cobalt nanoparticles and strong Co-N bonds synergistically form a threedimensional conductive network,increase the number of adsorption sites,and reduce the diffusion energy barrier,thereby facilitating the adsorption and the diffusion kinetics.These multiple effects lead to enhanced reversible capacities of 305 and 208.6 mAh g^−1 after 100 and 300 cycles at 0.05 and 0.1 A g^−1,respectively,demonstrating the applicability of the Co-NC anode for KIBs. | Xiaodong Shi Zhenming Xu Cheng Han Runze Shi Xianwen Wu Bingan Lu Jiang Zhou Shuquan Liang | 2021 | Nano-Micro Letters2021，13，2： | 4 |
| 15 | Porous CoF2 Spheres Synthesized by a One-Pot Solvothermal Method as High Capacity Cathode Materials for Lithium-Ion Batteries显示文摘直到现在,有用作高能力阴极材料的 CoF 2 范围的稀罕报告。此处,多孔的 CoF 2 范围为解放作为阴极材料被综合并且学习。当氟的符号采购原料,多孔的 CoF 2 范围被一个灵巧的一个壶 solvothermal 方法用一只保险箱和便宜的铵氟化物综合。合成的性质能避免使用腐蚀剂氟的符号来源和另外的高温度的热处理。结构,形态学和在不同反应时间和 solvothermal 温度获得的样品的电气化学的性能被调查。结果证明为 20 h 在 200 °C 获得的 CoF 2 范围显示出更好电气化学的表演,包括一个高起始的分泌物能力,好能力保留和高 Coulombic 效率。它能交付 537.8 mA•h•g −1 的一个高起始的分泌物能力并且在为锂离子电池用作阴极材料的 30 个周期以后把 127.4 mA•h•g 作为 −1 。好电气化学的表演可以被归因于好 crystallinity,多孔的结构和相对中间的范围尺寸。 | Qun Guan Jianli Cheng Xiaodong Li Bin Wang | 2017 | Chinese Journal of Chemistry2017，35，1： | 4 |
| 16 | Re-isolation of Wuxiang Virus from Wild Sandflies Collected from Yangquan County, China显示文摘We previously isolated a new species of the genus Phlebovirus from wild sandflies collected from Wuxiang County in central China,which named the Wuxiang virus(WUXV).In this study,we re-isolated the WUXV from wild sandflies collected from two villages in Yangquan County,China in 2019.Four virus isolates that caused cytopathic effects in BHK-21 cells were successfully isolated from sandfly specimens collected from chicken pens and sheep pens.Phylogenetic analyses of the L,M and S gene segments of the viruses revealed that the four virus strains represented the previously isolated WUXV.The minimum infection rate(MIR)of the virus isolated from the sheep pen was 3.21,and the MIR of the virus isolated from the chicken pen was 3.45.The positive rates of Wuxiang virus neutralizing antibodies in serum samples of local healthy people and domestic chickens were 8.7%(4/46)and 100%(4/4),respectively,suggesting that Wuxiang virus can infect human and animal.In view of the fact that Wuxiang virus is infectious to humans and animals and has a relatively wide geographical distribution in China,it is of great public health significance to strengthen the investigation and study on the infection status of Wuxiang virus in humans and animals. | Qinyan Wang Shihong Fu Jingxia Cheng Xiuyan Xu Jing Wang Bin Wu Xiaodong Tian Yan Li Ying He Fan Li Kai Nie Songtao Xu Bin Wang Huanyu Wang Xiaoqing Lu Guodong Liang | 2021 | Virologica Sinica2021，36，5： | 4 |
| 17 | Ultrafast optical nonlinearity of blue-emitting perovskite nanocrystals显示文摘Perovskite nanocrystals(NCs) have strong nonlinear optical responses with a number of potential applications,ranging from upconverted blue-lasing to the tagging of specific cellular components in multicolor fluorescence microscopy. Here, we determine the one-photon linear absorption cross section of two kinds of blue-emitting perovskite NCs, i.e., CsPbCl_3 and CsPb(Cl_(0.53)Br_(0.47))_3, by utilizing femtosecond transient absorption spectroscopy. The wavelength-dependent nonlinear refraction and two-photon absorption have been measured at wavelengths from 620 to 720 nm by performing Z-scan measurements. The nonlinear optical responses of CsPb(Cl_(0.53)Br_(0.47))_3 are much more pronounced than those of CsPbCl_3 due to the larger structural destabilization of the former. | JUNZI LI CAN REN XIN QIU XIAODONG LIN RUI CHEN CHENG YIN TINGCHAO HE | 2018 | Photonics Research2018，6，6： | 3 |
| 18 | The complete reference genome for grapevine (Vitis vinifera L.) genetics and breeding显示文摘Grapevine is one of the most economically important crops worldwide.However,the previous versions of the grapevine reference genome tipically consist of thousands of fragments with missing centromeres and telomeres,limiting the accessibility of the repetitive sequences,the centromeric and telomeric regions,and the study of inheritance of important agronomic traits in these regions.Here,we assembled a telomere-to-telomere(T2T)gap-free reference genome for the cultivar PN40024 using PacBio HiFi long reads.The T2T reference genome(PN_T2T)is 69 Mb longer with 9018 more genes identified than the 12X.v0 version.We annotated 67%repetitive sequences,19 centromeres and 36 telomeres,and incorporated gene annotations of previous versions into the PN_T2T assembly.We detected a total of 377 gene clusters,which showed associations with complex traits,such as aroma and disease resistance.Even though PN40024 derives from nine generations of selfing,we still found nine genomic hotspots of heterozygous sites associated with biological processes,such as the oxidation–reduction process and protein phosphorylation.The fully annotated complete reference genome therefore constitutes an important resource for grapevine genetic studies and breeding programs. | Xiaoya Shi Shuo Cao Xu Wang Siyang Huang Yue Wang Zhongjie Liu Wenwen Liu Xiangpeng Leng Yanling Peng Nan Wang Yiwen Wang Zhiyao Ma Xiaodong Xu Fan Zhang Hui Xue Haixia Zhong Yi Wang Kekun Zhang Amandine Velt Komlan Avia Daniela Holtgräwe Jérôme Grimplet JoséTomás Matus Doreen Ware Xinyu Wu Haibo Wang Chonghuai Liu Yuling Fang Camille Rustenholz Zongming Cheng Hua Xiao Yongfeng Zhou | 2023 | Horticulture Research2023，10，5： | 3 |
| 19 | A recombinant receptor-binding domain in trimeric form generates protective immunity against SARSCoV-2 infection in nonhuman primates显示文摘A safe and effective vaccine is critical to combat the COVID-19 pandemic.Here,we developed a trimeric SARS-CoV-2 receptor-binding domain(RBD)subunit vaccine candidate that simulates the natural structure of the spike(S)trimer glycoprotein.Immunization with the RBD trimer-induced robust humoral and cellular immune responses,and a high level of neutralizing antibodies was maintained for at least 4.5 months.Moreover,the antibodies that were produced in response to the vaccine effectively cross-neutralized the SARS-CoV-2501Y.V2 variant(B.1.351).Of note,when the vaccine-induced antibodies dropped to a sufficiently low level,only one boost quickly activated the anamnestic immune response,conferring full protection against a SARSCoV-2 challenge in rhesus macaques without typical histopathological changes in the lung tissues.These results demonstrated that the SARS-CoV-2 RBD trimer vaccine candidate is highly immunogenic and safe,providing long-lasting,broad,and significant immunity protection in nonhuman primates,thereby offering an optimal vaccination strategy against COVID-19. | Limin Yang Deyu Tian Jian-bao Han Wenhui Fan Yuan Zhang Yunlong Li Wenqiang Sun Yanqiu Wei Xiaodong Tian Dan-dan Yu Xiao-li Feng Gong Cheng Yuhai Bi Yong-tang Zheng Wenjun Liu | 2021 | The Innovation2021，2，3： | 3 |
| 20 | Open-pore LiFePO_4/C microspheres with high volumetric energy density for lithium ion batteries显示文摘LiFePO_4/C microspheres with different surface morphologies and porosities were prepared from different carbon sources.The effects of the surface morphology and pore structure of the microspheres on their electrochemical properties and electrode density were investigated.The electrochemical performance and electrode density depended on the morphology and pore structure of the LiFePO_4/C microspheres.Open-pore LiFePO_4/C microspheres with rough surfaces exhibited good adhesion with current collectors and a high electrode density(2.6g/cm^3).They also exhibited high performance in a half cell and full battery with a high volumetric energy density. | Lei Wen Xiaodong Hu Hongze Luo Feng Li Huiming Cheng | 2015 | Particuology2015，13，5： | 3 |
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