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| 1 | FibroSURE^(TM) and FibroScan~ in relation to treatment response in chronic hepatitis C virus显示文摘AIM:To compare histological endpoint assessment using noninvasive alternatives to biopsy during treatment in a chronic hepatitis C virus(HCV)cohort.METHODS:Patients with chronic HCV were randomized to receive interferon-based therapy for 24(genotypes 2/3)or 48(genotype 1)wk.FibroSURE~TM(FS)was assessed at baseline and at week-12 post-treatment follow-up.Baseline biopsy for METAVIR was assessed by a single pathologist.FibroScan~ transient elastogra-phy(TE)was performed during treatment in a patient subset.RESULTS:Two thousand and sixty patients(n = 253 in Asia)were classif ied as METAVIR F0-1(n = 1682)or F2-4(n = 378).For F2-4,FS(n = 2055)had sensitiv-ity and specif icity of 0.87 and 0.61,respectively,with area under the receiver-operating curve of 0.82;corre-sponding values for TE(n = 214)and combined FS/TE(n = 209)were 0.77,0.88 and 0.88,and 0.93,0.68 and 0.88.Overall FS/TE agreement for F2-4 was 71%(κ = 0.41)and higher in Asians vs non-Asians(κ = 0.86 vs 0.35;P < 0.001).Combined FS/TE had 97% accuracy in Asians(n = 33).Baseline FS(0.38 vs 0.51,P < 0.001)and TE(8.0 kPa vs 11.9 kPa,P = 0.006)scores were lower in patients with sustained virological response than in nonresponders,and were maintained through follow-up.CONCLUSION:FS and TE may reliably differentiate mild from moderate-advanced disease,with a potential for high diagnostic accuracy in Asians with chronic HCV. | Keyur Patel Mireen Friedrich-Rust Yoav Lurie Mircea Grigorescu Carol Stanciu Chuan-Mo Lee Eugene R Schiff Dieter Hussinger Michael P Manns Guido Gerken Isabelle Colle Michael Torbenson Erik Pulkstenis G Mani Subramanian John G McHutchison Stefan Zeuzem | 2011 | World Journal of Gastroenterology2011，17，41： | 4 |
| 2 | Context Effects in Subjective Mental Workload Ratings 显示文摘 | Colle H A Reid G B | 1998 | Human Factors1998，40，4： | 1 |
| 3 | Experimental mouse models for hepatocellular carcinoma research显示文摘 | Heindryckx F Colle I Van Vlierberghe H | 2009 | Int J Exp Pathol2009，90，4： | 1 |
| 4 | International HRM inthe 21st century: Emerging themes and contemporary debates 显示文摘 | SCUllION H COllINGS D G GUNNGlE P | 2007 | Human Resource Management Journal2007，17，4： | 1 |
| 5 | PhysicalLayer Security of TAS/MRC with Antenna Correlation显示文摘 | YANGN SURAWEERA H A COLLINGS I B | 2013 | IEEETransactions on Information Forensics and Security2013，8，1： | 1 |
| 6 | Impact of MELD on short-term and long-term outcome following liver transplantation:A European perspective显示文摘 | Nagler E Van V1ierberghe H Colle I | 2005 | Eur J Gastroenterol Hepatol2005，17，： | 1 |
| 7 | Modelling and hourly simulation of a solar ejector cooling system 显示文摘 | Vidal H Colle S | 2006 | Applied Thermal Engineering2006，26，7： | 1 |
| 8 | A Bifurcated Hydrogen-bouded Conformation in the d (A · T) Base Pairs of the DNA Dodecamer d (CGCAAATTTGCG) and its Complex with Distamycin显示文摘 | COLL M FREDERICK C A WANG A H | 1987 | Proc Natl Acad Sci USA1987，84，： | 1 |
| 9 | Effects of CO2 gas as leaks from geological storage sites on agro-ecosystems显示文摘 | Patil R H Colls J J Steven M D | 2010 | Energy2010，35，12： | 1 |
| 10 | Campylobaeter- associated Guillain-Barr syndrome after orthotopie liver transplantation for hepatitis C cirrhosis: a case report显示文摘 | Colle I Van Vlierberghe H Troisi R | 2002 | Hepatol Res2002，24，2： | 1 |
| 11 | Modelling and hourly simulation of a solar ejector cooling system显示文摘 | VIDAL H COLLE S PEREIRAL G | 2006 | Applied Thermal Engineering2006，26，7： | 1 |
| 12 | Global Talent Management显示文摘 | SCULLION H COLLINGS D G CALIGIURI P | 2010 | Journal of World Busi- ness2010，45，2： | 1 |
| 13 | The establishment of quality systems in veterinary diagnostic testing laboratories in developing coun- tries: experiences with the FAO/IAEA External Quality Assurance Programme显示文摘 | Colling A Jeggo M Louvandini H | 2008 | Accred Qual Assur2008，13，1： | 1 |
| 14 | The ealpain system 显示文摘 | Coll DE Thompson VF Li H | 2003 | Physiol Rev2003，83，3： | 1 |
| 15 | Obtaining patients' views ofnursing rare to inform the development of a patient satisfaction scale显示文摘 | Thomas L H Mac Millan J Mc Coll E el al | 1995 | lnt JQual Health Care1995，72，2： | 1 |
| 16 | Erosion of metals by fly ash particle显示文摘 | YEE K H SHAYLER P J COLLINGS N | 1983 | Wear1983，，91： | 1 |
| 17 | Systemic and splanchnic haemody namic effects of sildenafil in an in vivo animal model of cirrhosis support for a risk in cirhotic patients显示文摘 | Colle I De Vriese AS Van vlierberghe H | 2004 | Liver Int2004，24，1： | 1 |
| 18 | 显示文摘 | NEWSOME W H YEUNG J M COLLING P G | 1993 | J AOAC Int1993，76，： | 1 |
| 19 | , Kline-Rogers,Influence of con- current renal dysfunction on outcomes of patients with acute coronary syndromes and implications of the use of glycoprotein lib/Ilia inhibitors显示文摘 | Freeman R V Mehta R H A1 Badr W Cooper J V E Eagle K A J Am Coll Cardiol 41(5) | | 0，，： | 1 |
| 20 | Laminating Effects in Glued- Laminated Timber Beams显示文摘 | Robert H Francois Colling | 1995 | Journal of Structural Engineering1995，121，12： | 1 |
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