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| 1 | EIS study of the rust converter effectiveness under different conditions显示文摘 | A. Collazo X.R. Nóvoa C. Pérez B. Puga | 2007 | Electrochimica Acta2007，，25： | 3 |
| 2 | Matrix metalloproteases and their tissue inhibitors in non-alcoholic liver fibrosis of human immunodeficiency virus-infected patients显示文摘AIM To investigate the relationships among diverse metalloproteases(MMPs) and their tissue inhibitors(TIMPs) and non-alcoholic liver fibrosis in human immunodeficiency virus(HIV)-infected patients.METHODS Single nucleotide polymorphisms(SNPs) in MMPs, TNF-α and CCR5 genes, and serum levels of MMPs and TIMPs were determined in HIV-infected individuals with/out hepatitis C virus(HCV) coinfection. A total of 158 patients were included, 57 of whom were HCVcoinfected. All patients drank < 50 g ethanol/day. Diverse SNPs(MMP-1-1607 1G/2G, MMP-8-799C/T, MMP-9-1562 C/T, MMP-13-77A/G, TNF-α-308 G/A,CCR5-?32), and serum levels of MMPs(2, 3, 8, 9 and 10) and TIMPs(1, 2 and 4) were assessed. Liver fibrosis was determined by transient elastometry, although other non-invasive markers of fibrosis were also considered. Significant liver fibrosis(F ≥ 2) was defined by a transient elastometry value ≥ 7.1 kP a.RESULTS A total of 34 patients(21.5%) had liver fibrosis ≥ F2. MMP-2 and TIMP-2 serum levels were higher in patients with liver fibrosis ≥ F2(P = 0.02 and P = 0.03, respectively) and correlated positively with transient elastometry values(P = 0.02 and P = 0.0009, respectively), whereas MMP-9 values were negatively correlated with transient elastometry measurements(P = 0.01). Multivariate analyses showed that high levels of MMP-2(OR = 2.397; 95%CI: 1.191-4.827, P = 0.014) were independently associated with liver fibrosis ≥ F2 in the patients as a whole. MMP-2(OR = 7.179; 95%CI: 1.210-42.581, P = 0.03) and male gender(OR = 10.040; 95%CI: 1.621-62.11, P = 0.013) were also independent predictors of fibrosis ≥ F2 in the HCV-infected subgroup. Likewise, MMP-2, TIMP-2 and MMP-9 were independently associated with transient elastometry values and other non-invasive markers of liver fibrosis. None of the six SNPs evaluated had any significant association with liver fibrosis ≥ F2.CONCLUSION Certain MMPs and TIMPs, particularly MMP-2, seems to be associated with non-alcoholic liver fibrosis in HIVinfected patients with/without HCV coinfection. | Julio Collazos Eulalia Valle-Garay Tomás Suárez-Zarracina Angel-Hugo Montes José A Cartón Víctor Asensi | 2017 | World Journal of Virology2017，6，2： | 3 |
| 3 | Subsets of myeloid-de- rived suppressor cells in tumor-bearing mice 显示文摘 | Youn JI Nagaraj S Collazo M | 2008 | J Immunol2008，181，8： | 1 |
| 4 | Subsets of myeloid-derived suppressor cells in tumor-bearing mice 显示文摘 | Youn JI Nagaraj S Collazo M | 2008 | J Immunol2008，181，8： | 1 |
| 5 | Phenotypical and molecular characterization of the Tomato mottle Taino virus-Nicotiana megalosiphon interaction显示文摘 | COLLAZO C RAMOS P L CHAC(O)N O | | 0，，： | 1 |
| 6 | Subsets of myeloid derived suppressor cells in tumor-bearing mice 显示文摘 | Youn JI Nagaraj S Collazo M | 2008 | J Immuno12008，181，8： | 1 |
| 7 | Opportunistic infections of the CNS in patients with AIDS : diagnosis and management 显示文摘 | Collazos J | 2003 | CNS Drugs2003，17，12： | 1 |
| 8 | Hypersensitivity re-actions to rifampin显示文摘 | MARTINEZ E COLLAZOS J MAYO J | 1999 | Medicine1999，78，： | 1 |
| 9 | Portfolio selection with skewness in emerging market industries 显示文摘 | Canela M A Collazo E P | 2007 | Emerging Markets Review2007，8，3： | 1 |
| 10 | Opportunistic infections of the CNS in patients with AIDS: Diagnosis and management 显示文摘 | Collazos J | 2003 | CNS Drugs2003，17，12： | 1 |
| 11 | Characteriza- tion of the nature of granulocytic myeloid- derived suppressor cells in tumor-bearing mice显示文摘 | YOUN J I COLLAZO M SHALOVA I N | 2012 | J Leukoc Biol2012，91，1： | 1 |
| 12 | Sex differences in the clinical,immunological and virological parameters of HIV-infected patients treated with HAART显示文摘 | Collazos J Asensi V Carton JA | 2007 | AIDS2007，21，7： | 1 |
| 13 | Seasonal variation in haematological parameters in male and female Tinca tinca显示文摘 | María Eugenia Collazos Eduardo Ortega Carmen Barriga Ana Beatriz Rodrìguez | 1998 | Molecular and Cellular Biochemistry (-)1998，，1： | 1 |
| 14 | Subsets of myeloidderived suppressor cells in tumor-bearing mice显示文摘 | Youn JI Nagaraj S Collazo M | 2008 | J Immunol2008，181，8： | 1 |
| 15 | Characterisation of barrier properties of organic paints : the zinc phosphate effectiveness显示文摘 | M BEINENCOURT A COLLAZO M LZQUIERDO | 2003 | Progress in Organic Coatings2003，46，5： | 1 |
| 16 | Intermittent MT lI application evokes repeated anorexia and robust fat and weight loss显示文摘 | ZHANG Y COLLAZO R GAO Y | 2010 | Peptides2010，31，4： | 1 |
| 17 | Corrosion protection performance of sol-gel coatings doped with red mud applied on AA2024-T3 显示文摘 | COLLAZO A COVELO A NOVOA X R PEREZ C | 2012 | Progress in Organic Coatings2012，74，2： | 1 |
| 18 | Pathogen-specific loss ofhost resistance in mice lacking the IFN-y-inducible gene IGTP 显示文摘 | Taylor GA Collazo CM Yap GS | 2000 | ProcNatl Acad Sci USA2000，97，： | 1 |
| 19 | Seasonal variation in haematological parameters in male and female Tinca tinca显示文摘 | COLLAZOS M E ORTEGA E BARRIGA C | 1998 | Molecular and Cellular Biochemistry1998，183，： | 1 |
| 20 | Content Management Systems: Enriched learning opportunities for all?显示文摘 | Griet Lust Norma A. Juarez Collazo Jan Elen Geraldine Clarebout | 2011 | Computers in Human Behavior2011，，3： | 1 |
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