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| 1 | Could autophagy dysregulation link neurotropic viruses to Alzheimer’s disease?显示文摘Neurotropic herpesviruses have been associated with the onset and progression of Alzheimer’s disease,a common form of dementia that afflicts a large percentage of elderly individuals.Interestingly,among the neurotropic herpesviruses,herpes simplex virus-1,human herpesvirus-6A,and human herpesvirus-6B have been reported to infect several cell types present in the central nervous system and to dysregulate autophagy,a process required for homeostasis of cells,especially neurons.Indeed autophagosome accumulation,indicating an unbalance between autophagosome formation and autophagosome degradation,has been observed in neurons of Alzheimer’s disease patients and may play a role in the intracellular and extracellular accumulation of amyloidβand in the altered protein tau metabolism.Moreover,herpesvirus infection of central nervous system cells such as glia and microglia can increase the production of oxidant species through the alteration of mitochondrial dynamics and promote inflammation,another hallmark of Alzheimer’s disease.This evidence suggests that it is worth further investigating the role of neurotropic herpesviruses,particularly human herpesvirus-6A/B,in the etiopathogenesis of Alzheimer’s disease. | Maria Anele Romeo Alberto Faggioni Mara Cirone | 2019 | Neural Regeneration Research2019，14，9： | 6 |
| 2 | Comparison of Goldmann applanation tonometry and dynamic contour tonometry in the measurement of intraocular pressure in eyes with different corneal thicknesses显示文摘 | Roszkowska AM De Grazia L Cirone M | 2009 | Ophthalmologica2009，223，4： | 1 |
| 3 | Gene therapy of the brain in the dog model of Hurler' s ayndrome显示文摘 | Ciron C Desmaris N Colle MA | 2006 | Ann Neurol2006，60，2： | 1 |
| 4 | Heterogeneity within the hemagglutinin genes of canine distemper virus (CDV) strains detected in Italy显示文摘 | Martella V Cirone F Elia G | | 0，，4： | 1 |
| 5 | Heterogeneity within the hemagglutinin genes of Canine distemper virus (CDV) strains detected in Italy 显示文摘 | Martella V Cirone F Elia G | 2006 | Veterinary Microbiology2006，116，4： | 1 |
| 6 | Detection and genetic characterization of canine distemper virus(CDV) from free-ranging red foxes in Italy显示文摘 | MARTELLA V PRATELLI A CIRONE F | 2002 | Mol Cell Probes2002，16，1： | 1 |
| 7 | Epstein - Barr virus infection induces aberrant TLR activation pathway and fibroblast-myofibroblast conversion in scleroderma 显示文摘 | Farina A Cirone M York M | 2014 | Journal of Investigative Dermatology2014，134，4： | 1 |
| 8 | Heterogeneity within the hemagglutinin genes of canine distemper virus (CDV) strains detected in Italy显示文摘 | Martella V Cirone F Elia G | 2006 | Vet Microbiol2006，116，4： | 1 |
| 9 | Elevated antinuclear antibodies and altered anti-Epstein-Barr virus immune responses 显示文摘 | Cuomo L Cirone M Gregorio AO | 2014 | Virus Res2014，195，2： | 1 |
| 10 | HHV -8 reduces dendritic cell migration through down - regulation of cell - surfaceCCR6 and CCR7 and cytoskeleton reorganization 显示文摘 | Cirone M Conte V Farina A | 2012 | Virol J2012，9，： | 1 |
| 11 | Antibody levels and protection to canine parvovirus type 2显示文摘 | Elia G Cavalli A Cirone F | 2005 | J Vet Med B Infect Dis Vet Pub- lic Health2005，52，78： | 1 |
| 12 | Genotyping canine distemper virus (CDV) by a hemi-nested multiplex PCR provides a rapid approach for investigation of CDV outbreaks显示文摘 | Vito Martella Gabriella Elia Maria Stella Lucente Nicola Decaro Eleonora Lorusso Krisztian Banyai Merete Blixenkrone-M?ller Nguyen Thi Lan Ryoji Yamaguchi Francesco Cirone Leland Eugene Carmichael Canio Buonavoglia | 2007 | Veterinary Microbiology2007，，1： | 1 |
| 13 | Sedation and anesthesia mediated by distinct GABA(A)receptor isoforms显示文摘 | Reynolds DS Rosahl TW Cirone J | 2003 | J Neurosci2003，23，： | 1 |
| 14 | Elevated antinuclear antibodies and altered anti-Epstein-Barr virus immune responses 显示文摘 | Cuomo L Cirone M Di Gregorio AO | 2015 | ~irusRes2015，195，7： | 1 |
| 15 | Heterogeneity within the hemagglutinin genes of canine distemper virus (CDV) strains detected in Italy 显示文摘 | Martella V Cirone F Elia G | 2006 | Vet Microbiol2006，116，： | 1 |
| 16 | Multi-azimuth 3D survey in the Barents sea显示文摘 | Buia M Cirone C Leutscher J | 2010 | First Break2010，28，12： | 1 |
| 17 | Effect of microfluidization of heat-treated milk on rheology and sensory properties of reduced fat yoghurt显示文摘 | Chr Ian E Ciron Vivian L Gee Alan L Kelly | 2011 | Food Hydrocolloids2011，25，： | 1 |
| 18 | Heterogeneity within the hemagglutinin genes of canine distemper virus (CDV) strains detected in Italy显示文摘 | MARTELLA V CIRONE F ELIA G | 2006 | Vet Microbiol2006，116，4： | 1 |
| 19 | PGC-lalpha activity in nigral dopamine neurons determines vulnerability to alpha-synuclein 显示文摘 | Ciron C Zheng L Bobela W | 2015 | Acta Neuropathol Commun2015，3，1： | 1 |
| 20 | Genomic characterization of pestiviruses from lambs and kids in southern Italy显示文摘 | Pratelli A Martella V Cirone F | 2001 | J Virol Methods2001，94，12： | 1 |
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