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| 1 | Patulin Imprinted Nanoparticles Decorated Surface Plasmon Resonance Chips for Patulin Detection显示文摘In this study,the patulin imprinted and the non-imprinted nanoparticles are synthesized by the two-phase mini emulsion polymerization method and characterized by zeta-size analysis,Fourier transform infrared spectroscopy,and scanning electron microscopy.Afterwards,the patulin imprinted and the non-imprinted nanoparticles are attached on the surface of surface plasmon resonance(SPR)chips.The patulin imprinted and the non-imprinted SPR nanosensors are characterized by using atomic force microscope,ellipsometer,and contact angle measurements.Kinetic studies for patulin detection are carried out in the concentration range of 0.5nmol-750nmol.The limit of detection and the limit of quantification values are obtained as 0.011 nmol and 0.036 nmol,respectively.In all kinetic analysis,the response time is 13 min for equilibration,adsorption,and desorption cycles.The selectivity studies of the patulin imprinted and the non-imprinted SPR nanosensors are determined in the presence of ochratoxin A and aflatoxin Bl.In order to demonstrate the applicability,validation studies of the patulin imprinted SPR nanosensor are performed by liquid chromatography-tandem mass spectrometry(LC-MS). | Duygu CIMEN Nilay BERELI Adil DENIZLI | 2022 | Photonic Sensors2022，12，2： | 3 |
| 2 | Development of Rapid,Sensitive,and Effective Plasmonic Nanosensor for the Detection of Vitamins in Infact Formula and Milk Samples显示文摘The aim of the present study is to develop a surface plasmon resonance sensor for the detection of vitamin B2,vitamin B9,and vitamin B12 in food samples by using the molecular imprinting technique.The vitamin B2,vitamin B9,and vitamin B12 imprinted and the non-imprinted surface plasmon resonance sensor chip surfaces were characterized by using contact angle measurements,atomic force microscopy,ellipsometry,and Fourier transform infrared-attenuated total reflectance.The real-time detection of vitamin B2,vitamin B9,and vitamin B12 was analyzed by using aqueous solutions in the concentration range of 0.01 ng/mL−10 ng/mL for vitamin B2,0.1 ng/mL−8.0 ng/mL for vitamin B9,and 0.01 ng/mL−1.5 ng/mL for vitamin B12.The limit of detection values was calculated as 1.6×10^(−4) ng/mL for vitamin B2,13.5×10^(−4) ng/mL for vitamin B9,and 2.5×10^(−4) ng/mL for vitamin B12,respectively.Selectivity experiments were performed by using vitamin B1 and vitamin B6.The reproducibility of surface plasmon resonance sensors was investigated both on the same day and on different days for four times.Validation studies of the prepared surface plasmon resonance(SPR)sensors were performed by liquid chromatography-tandem mass spectrometry(LC-MS/MS). | Duygu CIMEN Adil DENIZLI | 2020 | Photonic Sensors2020，10，4： | 2 |
| 3 | Truncus arteriosus:Diagnosis with dual-source computed tomography angiography and low radiation dose显示文摘Truncus arteriosus is an uncommon congenital cardiac abnormality which is characterized by a single arterial trunk origin from the heart that supplies both the systemic,pulmonary and coronary circulation.We present a preterm newborn female patient with type 2 truncusarteriosus,left superior vena cava and aberrant subclavian artery diagnosed with low dose dual-source cardiac computed tomography(CT).We discuss that low dose dual-source cardiac CT has more advantages than other imaging methods and it is an important modality for assessment of patients with conotruncal anomalies such as truncusarteriosus. | Mustafa Koplay Derya Cimen Mesut Sivri Osman Güvenc Derya Arslan Alaaddin Nayman Bulent Oran | 2014 | World Journal of Radiology2014，6，11： | 2 |
| 4 | Protective effects of Rutin against methanol induced acute toxic optic neuropathy:an experimental study显示文摘AIM:To determine the effects of Rutin on methanol induced optic neuropathy and compare the results with the effects of ethanol.METHODS:Totally 30 rats were divided into 5 groups,with 6 rats in each group as follows:healthy controls(C),methotrexate(MTX),methotrexate+methanol(MTM),methotrexate+methanol+ethanol(MTME) and methotrexate+ methanol+Rutin(MTMR).In all rabbits except those of the control group,MTX,diluted in sterile serum physiologic,0.3 mg/kg per oral was applied for 7 d by the aid of a tube.After this procedure to the rats of MTM,MTME and MTMR groups,20% methanol with a dose of 3 g/kg per oral was given by the aid of a tube.In MTME group,4 h after the application of methanol,20% ethanol was applied by the same way with a dose of 0.5 g/kg.On the other hand,in MTMR group 4 h after the application of methanol,Rutin,which was dissolved in distilled water,was applied by the same way with a dose of 50 mg/kg.RESULTS:There were statistically significant differences in tissue 8-hydroxy-2 deoxyguanine(8-OHdG),interleukin-1β(IL-1β),tumor necrosis factor-alpha(TNF-α),malondialdehyde(MDA),myeloperoxidase(MPO).glutathione peroxidase(t GSH) and superoxide dismutase(SOD) levels between groups(P<0.001).In MTMR group tissue 8-OHdG,IL-1β,MDA,and MPO levels were similar with the healthy controls but significantly different than the other groups.In histopathological evaluations,in MTX group there was moderate focal destruction,hemorrhage and decrease innumber of astrocytes and oligodendrocytes;in MTM group there was severe destruction and edema with decrease in number of astrocytes and oligodendrocytes;in MTME group there was mild hemorrhage,mild edema,mildly dilated blood vessels with congestion while in MTMR group,optic nerve tissue was resembling the healthy controls.CONCLUSION:Rutin may prevent methanol-induced optic neuropathy via anti-inflammatory effects and decreasing the oxidative stress.New treatment options are warranted in this disease to avoid loss of vision in patients. | Nurdan Gamze Tasli Ferda Keskin Cimen Yücel Karakurt Turgay Ucak Renad Mammadov Bahadir Suleyman Nezahat Kurt Halis Suleyman | 2018 | International Journal of Ophthalmology(English edition)2018，11，5： | 2 |
| 5 | Comparison of buccal and nasal dexmedetomidine premeditation for pe- diatric patients显示文摘 | Cimen ZS Hanci A Sivrikaya GU | 2013 | Paediatr Anaesth2013，23，2： | 1 |
| 6 | Cardiac hydatid cysts with intracavitary expansion显示文摘 | Kaplan M Demirtas M Cimen S | 2001 | Ann Thorac Surg2001，71，： | 1 |
| 7 | Increased lipid peroxidation and impaired enzymatic antioxidant defense mechanism in thyroid tissue with multinodular goiter and papillary carcinoma显示文摘 | Erdamar H Cimen B Giilcemal H | 2010 | Clin Biochem2010，43，78： | 1 |
| 8 | Development and validation of mathematical model for control of constrained non-linear oil tanker motion显示文摘 | Cimen T | 2009 | Mathematical and Com- puter Modeling of Dynamical Systems: Methods Tools and Applications in Engineering and Related Sciences2009，15，1： | 1 |
| 9 | Congenital seminal vesicle cyst accompanying ipsilateral renal agenesis and rudimentary ureter显示文摘 | Cihanl A Cimen S Secil M | 2006 | Int Urol Nephrol2006，38，1： | 1 |
| 10 | Effects of pulsed versus conventional radiofrequency current on rabbit dorsal root ganglion morphology 显示文摘 | ERDINE S YUCEL A CIMEN A | 2005 | Eur J Pain2005，9，3： | 1 |
| 11 | Pereutaneous lumber nucleoplasty显示文摘 | Erdine S Ozyalein NS Cimen A | 2003 | Agri Dergiai2003，17，2： | 1 |
| 12 | Myofascial pain syndrome in the dif- ferential diagnosis of chronic abdominal pain显示文摘 | Cimen A Celik M Erdine S | 2004 | Agri2004，163，： | 1 |
| 13 | Concurrent microvascular and infarct remodeling after successful reperfusion of ST-elevation acute myocardial infarction显示文摘 | Sezer M Aslanger EK Cimen AO | 2010 | Circ Cardiovasc Intervm2010，3，3： | 1 |
| 14 | 15‐lipoxygenase‐1 exerts its tumor suppressive role by inhibiting nuclear factor‐kappa B via activation of PPAR gamma显示文摘 | I. Cimen E. Astarci S. Banerjee | 2011 | J Cell Biochem2011，，9： | 1 |
| 15 | Cardiac operations for patients with chronic liver disease显示文摘 | Kaplan M Cimen S Kut MS | 2002 | Heart Surg Forum2002，5，1： | 1 |
| 16 | Comparison of pulsed radiofrequency with conventional radiofrequency in the treatment of idiopathic trigeminal neuralgia显示文摘 | Erdine S Ozyalcin NS Cimen A Celik M Talu GK Di sci R | 2006 | Eur J Pain2006，6，： | 1 |
| 17 | Pegylated interferon alfa-2B induced lupus in a patient with chronic hepatitis B virus infection: case report显示文摘 | Sema Y?lmaz Kadriye Akar Cimen | 2009 | Clinical Rheumatology2009，，10： | 1 |
| 18 | Global optimal feedback control for general nonlinear systems with nonquadratic performance criteria显示文摘 | CIMEN T BANKS S P | 2004 | Systems & Control Letters2004，53，5： | 1 |
| 19 | Comparison of buccal and nasal dexmedetomidine premedication for pediatric patients 显示文摘 | Cimen ZS Hanci A Sivrikaya GU | 2013 | Paediatr Anaesth2013，23，2： | 1 |
| 20 | Congenital fusion of cervical vertebrae and its clinical significance显示文摘 | Erdil H Yildiz N Cimen M | 2003 | J Anat Soc India2003，52，2： | 1 |
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