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| 1 | Characterizations on Heavy-tailed Distributions by Means of Hazard Rate显示文摘Let F(x) be a distribution function supp0orted on[0,∞),with an equilibrium distribution function Fe(x).In this paper we shall study the function re(x)=(-in -↑Fe(x))′=-↑Fe(x)/∫x^∞-↑Fe(u)du,which is called the equilibrium hazard rate of F.By the limiting behavior of re(x) we give a criterion to identify F to be heavy-tailed or light-tailed.Two broad classes of heavy-tailed distributions are also introduced and strdied. | ChunSu Qi-heTang | 2003 | Acta Mathematicae Applicatae Sinica2003，19，1： | 18 |
| 2 | Separation and simultaneous quantitation of PGF2α and its epimer 8-iso-PGF2α using modifier-assisted differential mobility spectrometry tandem mass spectrometry显示文摘Because many therapeutic agents are contaminated by epimeric impurities or form epimers as a result of metabolism, analytical tools capable of determining epimers are increasingly in demand. This article is a proof-of-principle report of a novel DMS–MS/MS method to separate and simultaneously quantify epimers, taking PGF2α and its 8-epimer, 8-iso-PGF2α, as an example. Good accuracy and precision were achieved in the range of 10–500 ng/m L with a run time of only 1.5 min. Isopropanol as organic modifier facilitated a good combination of sensitivity and separation. The method is the first example of the quantitation of epimers without chromatographic separation. | Chunsu Liang Hui Sun Xiangjun Meng Lei Yina J.Paul Fawcett Huaidong Yu Ting Liu Jingkai Gu | 2018 | Acta Pharmaceutica Sinica B2018，8，2： | 3 |
| 3 | Almost Sure Convergence of the General Jamison Weighted Sum of B-Valued Random Variables显示文摘In this paper.two new functions are introduced to depict the Jamison weighted sum of random variables instead using the common methods.their properties and relationships are systematically discussed.We also analysed the implication of the conditions in previous papers.Then we apply these consequences to B-valued random variables.and greatly improve the original results of the strong convergence of the general Janfison weighted sum.Furthermore,our discussions are useful to the corresponding questions of real-valued random variables. | ChunSu | 2004 | Acta Mathematica Sinica,English Series2004，20，1： | 3 |
| 4 | Ginseng and diabetes 显示文摘 | XIE Jingtian MEHENDALE S YUAN Chunsu | 2005 | Am J Chin Med2005，33，3： | 1 |
| 5 | Ginsenosides from American ginseng: chemical and pharmacological diversity显示文摘 | Qi Lianwen Wang Chongzhi Yuan Chunsu | 2011 | Phytochemistry2011，72，： | 1 |
| 6 | Fuzzy AHP Analysis of Influence Factors of TBT on Mechanical and Electronic Products显示文摘 | Haiying Ren Chunsu Ji | 2006 | Journal of Systems Science and Information2006，4，1： | 0 |
| 7 | Induction of multiple subroutines of regulated necrosis in murine macrophages by natural BH3-mimetic gossypol显示文摘Macrophages are critical sentinel cells armed with multiple regulated necrosis pathways,including pyroptosis,apoptosis followed by secondary necrosis,and necroptosis,and are poised to undergo distinct form(s)of necrosis for tackling dangers of pathogenic infection or toxic exposure.The natural BH3-mimetic gossypol is a toxic phytochemical that can induce apoptosis and/or pyroptotic-like cell death,but what exact forms of regulated necrosis are induced remains largely unknown.Here we demonstrated that gossypol induces pyroptotic-like cell death in both unprimed and lipopolysaccharide-primed mouse bone marrow-derived macrophages(BMDMs),as evidenced by membrane swelling and ballooning accompanied by propidium iodide incorporation and lactic acid dehydrogenase release.Notably,gossypol simultaneously induces the activation of both pyroptotic and apoptotic(followed by secondary necrosis)pathways but only weakly activates the necroptosis pathway.Unexpectedly,gossypol-induced necrosis is independent of nucleotide-binding oligomerization domain-like receptor family pyrin domain containing 3(NLRP3)inflammasome,as neither inhibitor for the NLRP3 pathway nor NLRP3 deficiency protects the macrophages from the necrosis.Furthermore,necrotic inhibitors or even pan-caspase inhibitor alone does not or only partly inhibit such necrosis.Instead,a combination of inhibitors composed of pan-caspase inhibitor IDN-6556,RIPK3 inhibitor GSK′872 and NADPH oxidase inhibitor GKT137831 not only markedly inhibits the necrosis,with all apoptotic and pyroptotic pathways being blocked,but also attenuates gossypol-induced peritonitis in mice.Lastly,the activation of the NLRP3 pathway and apoptotic caspase-3 appears to be independent of each other.Collectively,gossypol simultaneously induces the activation of multiple subroutines of regulated necrosis in macrophages depending on both apoptotic and inflammatory caspases. | Meiyan Zhong Yuanting Huang Bo Zeng Lihui Xu Chunsu Zhong Jiahao Qiu Xunjia Ye Mingye Chen Bo Hu Dongyun Ouyang Xianhui He | 2022 | Acta Biochimica et Biophysica Sinica2022，54，1： | 0 |
| 8 | Research on the Optimization of Teaching and Learning Path in the Context of Educational Data显示文摘With the repeated in-depth development of the technological revolution,the combination of education and technology constantly shows a new form.Modern education and Internet education have become the new direction of the current education development efforts.The development of technology has brought great Gospel for the national education.Based on this,from the traditional and modern perspectives,this paper discusses the form and significance of teaching and learning paths,to show the new value of education brought by the change of teaching and learning paths under the background of educational data. | Wenya Wang Chunsu Zhang | 2021 | Journal of Contemporary Educational Research2021，5，4： | 0 |
| 9 | Research on Educational Development from the Perspective of “Internet +”显示文摘As the information society continues to develop and progress,“Internet+”as new business type of the Internet has brought new opportunities to traditional industries.In particular,“Internet+”as an emerging information technology has profoundly changed the education industry.In order to explore the educational development from the perspective of“Internet+”,this paper first introduces the concept and key characteristics of“Internet+”,and then probes into the opportunities brought by“Internet+”to educational development from three aspects:course,teaching/learning and evaluation,and finally puts forward two suggestions for the educational development in the view of“Internet+”for future reference. | Zhuangfei Wang Chunsu Zhang | 2020 | Journal of Contemporary Educational Research2020，4，12： | 0 |
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