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| 1 | Comparison of high-resolution ultrasound and MR-enterography in patients with inflammatory bowel disease显示文摘AIM:To compare the results of high-resolution ultrasound(HR-US) and magnetic resonance enterography(MRE) examinations in patients with inflammatory bowel disease(IBD).METHODS:The reports of 250 consecutive cases with known IBD,who had an MRE and HR-US examination,were retrospectively analyzed.Using a patient-based approach we evaluated morphological disease features such as affected bowel wall,stenosis,abscess and fistula.The comparison between the two modalities was based on the hypothesis,that any pathological change described in any imaging modality was a true finding,as no further standard of reference was available for complete assessment.RESULTS:Two hundred and fifty examinations representing 207 different patients were evaluated.Both modalities assessed similar bowel wall changes in 65% of the examinations,with more US findings in 11% and more MRE findings in 15%.When the reports were analyzed with regard to 'bowel wall inflammation',US reported more findings in 2%,while MRE reported more findings in 53%.Stenoses were assessed to be identical in 8%,while US found more in 3% and MRE in 29%(P < 0.01).For abscess detection,US showed more findings in 2%(n = 4) while MRE detected more in 6%(n = 16).US detected more fistulas in 1%(n = 2),while MRE detected more in 13%(n = 32)(P < 0.001).The most common reason for no detected pathology by US was a difficult to assess anatomical region(lesser pelvis,n = 72).CONCLUSION:US can miss clinically relevant pathological changes in patients with IBD mostly due to difficulty in assessing certain anatomical regions. | Andreas G Schreyer Cynthia Menzel Chris Friedrich Florian Poschenrieder Lukas Egger Christian Dornia Gabriela Schill Lena M Dendl Doris Schacherer Christl Girlich Ernst-Michael Jung | 2011 | World Journal of Gastroenterology2011，17，8： | 7 |
| 2 | Escitalopram-induced liver injury: A case report and review of literature显示文摘BACKGROUND Depression is a growing public health problem that affects over 350 million people globally and accounts for approximately 7.5%of healthy years lost due to disability.Escitalopram,one of the first-line medications for the treatment of depression,is a selective serotonin reuptake inhibitor and one of the most commonly prescribed antidepressant medications worldwide.Although thought to be generally safe and with minimal drug-drug interactions,we herein present an unusual case of cholestatic liver injury,likely secondary to escitalopram initiation.CASE SUMMARY A 56-year-old Chinese lady presented with fever and cholestatic liver injury two weeks after initiation of escitalopram for the treatment of psychotic depression.Physical examination was unremarkable.Further investigations,including a computed tomography scan of the abdomen and pelvis and tests for hepatitis A,B and C and for autoimmune liver disease were unyielding.Hence,a diagnosis of escitalopram-induced liver injury was made.Upon stopping escitalopram,repeat liver function tests showed downtrending liver enzymes with eventual normalization of serum aspartate aminotransferase and alanine aminotransferase one-week post-discharge.CONCLUSION Clinicians should be aware of the possibility of escitalopram-induced liver injury when initiating depressed patients on antidepressant treatment.This requires extra vigilance as most patients may remain asymptomatic.Measurement of liver function tests could be considered after initiation of antidepressant treatment,especially in patients with pre-existing liver disease. | Qin Xiang Ng Christl Suet Kwan Yong Wayren Loke Wee Song Yeo Alex Yu Sen Soh | 2019 | World Journal of Hepatology2019，11，10： | 3 |
| 3 | Chemical heterogeneity of humic substances: characterization of size fractions obtained by hollow-fiber ultrafiltration 显示文摘 | Christl I Knicker H Kogel-Knabner I | 2000 | Europ J of Soil Sci2000，51，4： | 2 |
| 4 | C-1s NEXAFS spectroscopy reveals chemical fractionation of humic acid by cation-induced coagulation显示文摘 | Christl I Kretzschmar R | 2007 | Environ Sci Technol2007，41，6： | 1 |
| 5 | TNF-α pretreatment induces protective effects against focal cerebral ischemia in mice显示文摘 | Nawashiro H Tasaki K Christl AR | 1997 | J Cereb Blood Flow Metab1997，17，5： | 1 |
| 6 | Bats:A new tool for AMS data reduction显示文摘 | Wacker L Christl M Synal H A | 2010 | Nuclear Instruments and Methods in Physics Research Section B:Beam Interactions with Materials and Atoms2010，268，7： | 1 |
| 7 | Reduction and reoxidation of humic acid:influence on spectroscopic properies and proton binding显示文摘 | Maurer F Christl I Kretzschmar R | 2010 | Environmental Science & Technology2010，44，15： | 1 |
| 8 | Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong显示文摘 | Christl A Donnelly Azra C Ghani Gabriel M Leung | 2003 | Lancet2003，361，： | 1 |
| 9 | The role of smooth muscle in the pathogenesis of pelvic organ prolapse—an immunohistochemical and morphometric analysis of the cervical third of the uterosacral ligament显示文摘 | Christl Reisenauer Thomas Shiozawa Matthias Oppitz Christian Busch Andreas Kirschniak Tanja Fehm Ulrich Drews | 2008 | International Urogynecology Journal2008，，3： | 1 |
| 10 | Effect of humie and fulvie acid concentrations and ionic strength on eopper and lead binding 显示文摘 | CHRISTL I METZGER A HEIDMANN I et ul | 2005 | Environmental Science & Technology2005，39，14： | 1 |
| 11 | FGF-4 or FGF-2 administration induces apoptosis,collagen type I expression,and mineralization in the developing coronal suture显示文摘 | Hans-van L Christl VK | 2001 | J Craniofac Surg2001，12，： | 1 |
| 12 | Aerobic reduction of Chromium( VI ) by Pseudomonas corrugata 28 : Influence of metabolism and fate of reduced Chromium 显示文摘 | Christl I Imseng M Tatti E | 2012 | Geomicrobiol J2012，29，2： | 1 |
| 13 | Competitive sorption of copper and lead at the oxid - water interface: Implications for surface site density 显示文摘 | Iso Christl | 1999 | Geochimica et Cosmochimica Acta1999，63，1920： | 1 |
| 14 | Advanced series compensation with thyristor controlled impedance 显示文摘 | CHRISTL N HEDIN R SADEK K | 1992 | CIGRE Paper1992，11，7： | 1 |
| 15 | Anatomical conditions for pelvic floor renconstruction with polypropylene implant and its application for the treatment of vaginal prolapse显示文摘 | Christl R Andreas K Ulrich D et a1 | 2007 | Eur J Obstet Gynecol R B2007，131，： | 1 |
| 16 | Quantum entanglement at ambient conditions in a macroscopic solid-state spin ensemble 显示文摘 | Klimov P V Falk A L Christle D J | 2015 | Science Advances2015，1，15： | 1 |
| 17 | Anatomical conditions for pelvic floor renconstruction with polypropylene implant and its application for the treatment of vaginal prolapse显示文摘 | Christl R Andreas K Ulrich D | | 0，，06： | 1 |
| 18 | Plasticity and hydrolytic weakening of quartz single crystals显示文摘 | Christle J M | 1984 | J Geophy Res1984，89，6： | 1 |
| 19 | Chemical heterogeneity of humic substances: Characterization of size fractions obtained by hollow-fibre ultrafiltration 显示文摘 | Christl I Knicker H Kogel-Knabner I | 2000 | Eur J Soil Sci2000，51，4： | 1 |
| 20 | A Re-appraisal of Merchant's contribution to the theory of consolidation显示文摘 | CHRISTLE I F | 1964 | Geotechnique1964，14，4： | 1 |
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