|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A long-term follow-up study on hepatitis B surface antigen-positive patients undergoing allogeneic hematopoietic stem cell transplantation显示文摘 | Hui CK Lie A Au WY Leung YH Ma SY Cheung WW Zhang HY Chim CS Kwong YL Liang R Lau GK | 2006 | 中国生物学文摘2006，20，5： | 10 |
| 2 | Risk factors and natural history of breast cancer in younger Chinese women显示文摘AIM: To investigate the age differences in the risk factors, clinicopathological characteristics and patterns of treatment of female breast cancer patients. METHODS: Seven thousand one hundred and fiftytwo women with primary breast cancer from the Hong Kong Breast Cancer Registry were recruited after receiving patients' consent, they were asked to complete standardized questionnaires which captured their sociodemographic characteristics and risk factors associated with breast cancer development. Among them, clinicopathological data and patterns of treatment were further collected from medical records of 5523 patients with invasive breast cancers. Patients were divided into two groups according to the age at diagnosis: younger(< 40 years old) vs older patients(≥ 40 years old) for subsequent analyses.RESULTS: Analysis on the sociodemographic characteristics and exposure to risk factors were performed on 7152 women with primary breast cancer and the results revealed that younger patients were more likely to have unhealthy lifestyles; these include a lack of exercise(85.4% vs 73.2%, P < 0.001), having high stress in life(46.1% vs 35.5%, P < 0.001), having dairy/meat-rich diets(20.2% vs 12.9%, P < 0.001),having alcohol drinking habit(7.7% vs 5.2%, P = 0.002). Younger patients were also more likely to have hormone-related risk factors including nulliparity(43.3% vs 17.8%, P < 0.001) and an early age at menarche(20.7% vs 13.2%, P < 0.001). Analyses on clinicopathological characteristics and patterns of treatment were performed on 5523 women diagnosed with invasive breast cancer. The invasive tumours in younger patients showed more aggressive pathological features such as having a higher percentage of grade 3 histology(45.7% vs 36.5%, P < 0.001), having a higher proportion of tumours with lymphovascular invasion(39.6% vs 33.2%, P = 0.003), and having multifocal disease(15.7% vs 10.3%, P < 0.001); they received different patterns of treatment than their older counterparts.CONCLUSION: Younger patients in Hong Kong are more likely to encounter risk factors associated with breast cancer development and have more aggressive tumours than their older counterparts. | Winnie Yeo Hang-Mei Lee Amy Chan Emily YY Chan Miranda CM Chan Keeng-Wai Chan Sharon WW Chan Foon-Yiu Cheung Polly SY Cheung Peter HK Choi Josette SY Chor William WL Foo Wing-Hong Kwan Stephen CK Law Lawrence PK Li Janice WH Tsang Yuk Tung Lorna LS Wong Ting-Ting Wong Chun-Chung Yau Tsz-Kok Yau Benny CY Zee | 2014 | World Journal of Clinical Oncology2014，5，5： | 4 |
| 3 | Drug adherence and the incidence of coronary heart disease-and stroke-specific mortality among 218,047 patients newly prescribed an antihypertensive medication'a five-year cohort study显示文摘 | Wong MC1 Tam WW Cheung CS | 2013 | Int J Cardiol2013，168，2： | 1 |
| 4 | Comparison of dynamic helical CT and dynamic MR imaging in the evaluation of pelvic lymph nodes in cervical carcinoma 显示文摘 | Yang WT Lam WW Yu MY Cheung TH Metreweli C | 2000 | AJR2000，175，： | 1 |
| 5 | Retracted: outcome and immune reconstitution of HBV-specific immunity in patients with reactivation of occult HBV infection after alemtuzumab-containing chemotherapy regimen显示文摘 | Hui CK Cheung WW Leung KW | 2008 | Hepatology2008，48，2： | 1 |
| 6 | Inflammation and cachexia in chronic kidney disease 显示文摘 | Cheung WW Paik KH Mak RH | 2010 | Pediatr Nephrol2010，25，4： | 1 |
| 7 | Vertebroplasty by use of a strontium-containing bioactive bone cement显示文摘 | Lu WW Luk KD | 2005 | Spine2005，30，17： | 1 |
| 8 | Bioactive bone cement as a prin- cipal fixture for spinal burst fracture:an in vitro biomechanical and morphologic study 显示文摘 | Lu WW Cheung KM Li YW | 2001 | Spine2001，26，： | 1 |
| 9 | Bioactive bone cement as a principal fixture for spinal burst fracture: an in vitro biomechanical and morphologic study 显示文摘 | Lu WW Cheung KM Li YW | 2001 | Spine2001，26，： | 1 |
| 10 | The growth hormone-insulin-like growth faetor-I axis in chronic kidney disease显示文摘 | Mak RH Cheung WW | 2008 | Growth Horm IGF Res2008，18，1： | 1 |
| 11 | Kinetics and risk of de novo hepatitis B infection in HBsAgnegative patients undergoing cytotoxic chemotherapy 显示文摘 | Hui CK Cheung WW Zhang HY | 2006 | Gastroenterology2006，131，1： | 1 |
| 12 | Is regular follw-up scan for giant liver haemangioma necessary? 显示文摘 | Ng WW Cheung YS Lee KF | 2007 | Hong Kong Med J2007，13，5： | 1 |
| 13 | Results of high-density silicone oil as a tamponade agent in macular hole retinal detachment in patients with high myopia显示文摘 | Cheung BT Lai TY Yuen CY Lai WW Tsang CW Lam DS | 2007 | Br J Ophthalmol2007，91，6： | 1 |
| 14 | Results of high-density silicone oil as a tamponade agent in macular hole retinai detachment in patients with high myopia显示文摘 | Cheung BT Lai TY Yuen CY Lai WW Tsang CW Lam DS | 2007 | Br J 0phthalmol2007，91，6： | 1 |
| 15 | Inhibitionof gliomainvasion by overexpression of pigment epithelium-de-rived factor显示文摘 | Guan M Pang CP Yam HF Cheung KF Liu WW Lu Y | 2004 | Cancer Gene Ther2004，11，5： | 1 |
| 16 | Bioactive bone cement as a principal fixture for spinal burst fracture:an in vitro biomechanical and morphologic study显示文摘 | Lu WW Cheung KM Li YW | | 0，，1976： | 1 |
| 17 | Pars plana vitrectomy and perfluoropropane(C3F8) tamponade for retinal detachment due to myopic macular hole:a prognostic fact or analysis显示文摘 | Lam RF Lai WW Cheung BT | | 0，，06： | 1 |
| 18 | Endolaparoseopic approach vs conventional open surgery in the treatment of obstructing left- sided colon cancer: a randomized controlled trial显示文摘 | Cheung HY Chung CC Tsang WW | 2009 | Arch Surg2009，144，12： | 1 |
| 19 | Impact of right ventricular dilation on left ventricular myocardial deformation in patients after surgical repair of tetralogy of Fallot显示文摘 | Cheung EW Liang X Lam WW | 2009 | Am J Cardiol2009，104，9： | 1 |
| 20 | Hepatitis B reactivation after withdrawal of pre-emptive lamivudine in patients with haematological malignancy on completion of cytotoxic chemo- therapy显示文摘 | Hui CK Cheung WW Au WY | 2005 | Gut2005，54，11： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员