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| 1 | Systems metabolic engineering strategies for the production of amino acids显示文摘Systems metabolic engineering is a multidisciplinary area that integrates systems biology,synthetic biology and evolutionary engineering.It is an efficient approach for strain improvement and process optimization,and has been successfully applied in the microbial production of various chemicals including amino acids.In this review,systems metabolic engineering strategies including pathwayfocused approaches,systems biology-based approaches,evolutionary approaches and their applications in two major amino acid producing microorganisms:Corynebacterium glutamicum and Escherichia coli,are summarized. | Qian Ma Quanwei Zhang Qingyang Xu Chenglin Zhang Yanjun Li Xiaoguang Fan Xixian Xie Ning Chen | 2017 | Synthetic and Systems Biotechnology2017，2，2： | 10 |
| 2 | A Novel Approach to Automatic Security Protocol Analysis Based on Authentication Event Logic显示文摘Since security protocols form the cornerstones of modern secure networked systems, it is important to develop informative, accurate, and deployable approach for finding errors and proving that protocols meet their security requirements. We propose a novel approach to check security properties of cryptographic protocols using authentication event logic. Compared with logic of algorithm knowledge, authentication event logic guarantees that any well-typed protocol is robustly safe under attack while reasoning only about the actions of honest principals in the protocol. It puts no bound on the size of the principal and requires no state space enumeration and it is decidable. The types for protocol data provide some intuitive explanation of how the protocol works. Our approach has led us to the independent rediscovery of flaws in existing protocols and to the design of improved protocols. | XIAO Meihua MA Chenglin DENG Chunyan ZHU Ke | 2015 | Chinese Journal of Electronics2015，24，1： | 10 |
| 3 | Synthesis of Fe_3O_4@SiO_2@polymer nanoparticles for controlled drug release显示文摘Novel multifunctional nanoparticles containing a magnetic Fe3O4@SiO2 sphere and a biocompatible block copolymer poly(ethylene glycol)-b-poly(aspartate)(PEG-b-PAsp) were prepared.The silica coated on the superparamagnetic core was able to achieve a magnetic dispersivity,as well as to protect Fe3O4 against oxidation and acid corrosion.The PAsp block was grafted to the surface of Fe3O4@SiO2 nanoparticles by amido bonds,and the PEG block formed the outermost shell.The anticancer agent doxorubicin(DOX) was loaded into the hybrid nanoparticles via an electrostatic interaction between DOX and PAsp.The release rate of DOX could be adjusted by the pH value. | WU ChengLin,HE Huan,GAO HongJun,LIU Gan,MA RuJiang,AN YingLi & SHI LinQi Key Laboratory of Functional Polymer Materials,Ministry of Education Institute of Polymer Chemistry,Nankai University,Tianjin 300071,China | 2010 | Science China Chemistry2010，53，3： | 9 |
| 4 | Advanced hydrogels for the repair of cartilage defects and regeneration显示文摘Cartilage defects are one of the most common symptoms of osteoarthritis(OA),a degenerative disease that affects millions of people world-wide and places a significant socio-economic burden on society.Hydrogels,which are a class of biomaterials that are elastic,and display smooth surfaces while exhibiting high water content,are promising candidates for cartilage regeneration.In recent years,various kinds of hydrogels have been developed and applied for the repair of cartilage defects in vitro or in vivo,some of which are hopeful to enter clinical trials.In this review,recent research findings and developments of hydrogels for cartilage defects repair are summarized.We discuss the principle of cartilage regeneration,and outline the requirements that have to be fulfilled for the deployment of hydrogels for medical applications.We also highlight the development of advanced hydrogels with tailored properties for different kinds of cartilage defects to meet the requirements of cartilage tissue engineering and precision medicine. | Wei Wei Yuanzhu Ma Xudong Yao Wenyan Zhou Xiaozhao Wang Chenglin Li Junxin Lin Qiulin He Sebastian Leptihn Hongwei Ouyang | 2021 | Bioactive Materials2021，6，4： | 8 |
| 5 | Enrichment of putative human epidermal stem cells based on cell size and collagen type IV adhesiveness显示文摘人的表皮的干细胞(EpSCs ) 的丰富和鉴定具有为基本研究和临床的申请的首要的重要性。尽管为 EpSCs 的丰富的几条途径被建立了,充实可行 EpSCs 的一张纯人口仍然是一项挑战性的任务。一条改进途径值得发展提高 EpSCs 的纯净和生存能力。这里,我们报导那种房间尺寸与骨胶原类型 IV 粘着性结合了能在一条改进途径被使用充实纯、可行的人的 EpSCs。我们分开了很快支持者 keratinocytes 进从 5-7 microm (人口 A )在尺寸 的三张人口到 7-9 microm (人口 B ),到>或在直径的 =9 microm (人口 C ),并且发现人的通常认为的 EpSCs 能进一步与最小的尺寸在人口 A 被充实。在三张人口之中,人口 A 显示了 beta1-integrin 受体的最高的密度,在 G0/G1 阶段包含了房间的最高的百分比,显示出最高的原子核到细胞质比率,并且拥有了最高的殖民地形成效率(CFE ) 。当注入了鼠科的胚囊时,这些房间参予了多织物形成。与根据 beta1-integrin 抗体染色排序通常认为的 EpSCs 的一条以前的途径相比,更显著地, EpSCs 的生存能力由改进途径充实显著地被提高。我们的结果为人的 EpSCs 的丰富提供通常认为的策略,并且在干细胞生物学鼓励进一步的学习进房间尺寸的角色。 | Juxue Li Chenglin Miao Welxiang Guo Liwei Jia Jiaxi Zhou Baohua Ma Sha Peng Shuang Liu Yujing Cao Enkui Duan | 2008 | Cell Research2008，18，3： | 8 |
| 6 | Heavy metal contamination of urban topsoil in a petrochemical industrial city in Xinjiang, China显示文摘Heavy metal pollution is a widespread phenomenon in many countries of the world.In this study,we conducted a field investigation to assess the status of heavy metal pollution in urban soils of Dushanzi,a district of Karamay city in Xinjiang,China.A total of 56 soil samples in the topsoil layer of 0–15 cm were collected within the urban area and seven elements(Cu,Zn,Cd,Pb,Cr,As and Ni) were analyzed.The mean concentrations of these metals were all higher than their corresponding background values of soils in Xinjiang.We used the pollution index and ecological risk index to assess the degree of heavy metal pollution and the potential ecological risk of urban soils.The pollution index values of Cu,Zn,Cd,Pb,Cr,As and Ni were 1.81,1.35,4.64,1.27,1.80,1.39 and 1.22,respectively;and the potential ecological risk index values for them were 12.03,1.79,185.05,8.39,4.78,18.44 and 1.79,respectively.These results indicated that urban soils in Dushanzi were polluted by heavy metals to some extent and demonstrated a high ecological risk,as influenced by industrial activities.Cd was the key element for the metal pollution of urban soils in the study area.Correlation analyses,principal component analysis coupled with the spatial distribution maps of element concentrations further revealed that heavy metal pollution of urban soils can be mainly attributed to petrochemical industry,coal chemical industry,traffic and commercial activities. | WANG Wei LAI Yingshuai MA Yuanyuan LIU Zilong WANG Shufen HONG Chenglin | 2016 | Journal of Arid Land2016，8，6： | 7 |
| 7 | Use of catalytic wet air oxidation (CWAO) for pretreatment of high-salinity high-organic wastewater显示文摘Catalytic wet air oxidation(CWAO)coupled desalination technology provides a possibility for the effective and economic degradation of high salinity and high organic wastewater.Chloride widely occurs in natural and wastewaters,and its high content jeopardizes the efficacy of Advanced oxidation process(AOPs).Thus,a novel chlorine ion resistant catalyst Bsite Ru doped LaFe_(1-x)Ru_(x)O_(3-)δin CWAO treatment of chlorine ion wastewater was examined.Especially,LaFe_(0.85)Ru_(0.15)O_(3-δ)was 45.5% better than that of the 6%RuO_(2)@TiO_(2)(commercial carrier)on total organic carbon(TOC)removal.Also,doped catalysts LaFe_(1-x)Ru_(x)O_(3-)δshowed better activity than supported catalysts RuO_(2)@LaFeO_(3) and RuO_(2)@TiO_(2) with the same Ru content.Moreover,LaFe_(0.85)Ru_(0.15)O_(3-)δhas novel chlorine ion resistance no matter the concentration of Cl^(−) and no Ru dissolves after the reaction.X-ray diffraction(XRD)refinement,X-ray photoelectron spectroscopy(XPS),transmission electron microscope(TEM),and X-ray absorption fine structure(XAFS)measurements verified the structure of LaFe_(0.85)Ru_(0.15)O_(3-)δ.Kinetic data and density functional theory(DFT)proved that Fe is the site of acetic acid oxidation and adsorption of chloride ions.The existence of Fe in LaFe_(0.85)Ru_(0.15)O_(3-)δcould adsorb chlorine ion(catalytic activity inhibitor),which can protect the Ru site and other active oxygen species to exert catalytic activity.This work is essential for the development of chloride-resistant catalyst in CWAO. | Wenjing Sun Hongxia Lv Lei Ma Xiangdong Tan Chengyu Jin Huiling Wu Lili Chen Mengyang Liu Huangzhao Wei Chenglin Sun | 2022 | Journal of Environmental Sciences2022，34，10： | 4 |
| 8 | An Asynchronous Quasi-Cloud/Edge/Client Collaborative Federated Learning Mechanism for Fault Diagnosis显示文摘Although the federated learning method has the ability to balance data and protect data privacy by means of model aggregation,while the existing methods are difficult to achieve the effectiveness of centralized learning under data sharing.The existing federated structure only has a certain degree of confidentiality for data privacy,that is to say,each client can reconstruct a part of the information of other clients based on the model parameters shared between the server and the clients under certain conditions.In order to make the federated learning mechanism more confidential,we breaks the existing mechanism that the parameters between the federated model and the client model are completely shared,and establishes a new asynchronous quasi-cloud/edge/client collaborative federated learning mechanism.We construct a hierarchical multi-level confidential communication network,where the network parameters are shared in a way of quasi-cloud/edge/client coordination without data communication.The cloud and the edges respectively use the sequential Kalman filter algorithm to perform an asynchronous fusion of the network parameters uploaded in their respective fusion centers for the next round of updates;The effectiveness of the proposed algorithm is verified on the data of a type of rotating machinery. | MA Xue WEN Chenglin | 2021 | Chinese Journal of Electronics2021，30，5： | 2 |
| 9 | Aluminum hydride for solid-state hydrogen storage:Structure,synthesis, thermodynamics, kinetics, and regeneration显示文摘Aluminum hydride(AlH3) is a binary metal hydride that contains more than 10.1 wt% of hydrogen and possesses a high volumetric hydrogen density of 148 kg H2 m^(-3).Pristine AlH3 can readily release hydrogen at a moderate temperature below 200℃.Such high hydrogen density and low desorption temperature make AlH3 one of most promising hydrogen storage media for mobile application.This review covers the research activity on the structures,synthesis,decomposition thermodynamics and kinetics,regeneration and application validation of AlH3 over the past decades.Finally,the future research directions of AlH3 as a hydrogen storage material will be revealed. | Haizhen Liu Longfei Zhang Hongyu Ma Chenglin Lu Hui Luo Xinhua Wang Xiantun Huang Zhiqiang Lan Jin Guo | 2021 | Journal of Energy Chemistry2021，30，1： | 2 |
| 10 | Discovery of Palaeozoic Karsts in the Qaidam Basin and Their Oil and Gas Prospects显示文摘Objective Complex geological factors have been constraining the oil and gas exploration in the Paleozoic strata of the Qaidam Basin,although there are high-quality hydrocarbon source rocks.One of the most important reasons may be reservoir densification due to the multiple stages of destructive cementation,which has hindered our understanding of the Paleozoic petroleum enrichment rules in the Qaidam basin.In recent years,the | PENG Bo LIU Chenglin LI Zongxing MA Yinsheng CAO Jun WANG Bing ZHANG Xu | 2016 | Acta Geologica Sinica(English Edition)2016，90，5： | 2 |
| 11 | Geothermal Field and Tectono-Thermal Evolution since the Late Paleozoic of the Qaidam Basin,Western China显示文摘The Qaidam basin is the largest intermountain basin inside Tibet,and is one of the three major petroliferous basins in western China.This study discussed the geothermal field and tectono-thermal evolution of the basin,in an effort to provide evidence for intracontinental or intraplate continental dynamics and basin dynamics,petroleum resources assessment,and to serve petroleum production. | LI Zongxing LIU Chenglin MA Yinsheng | 2015 | Acta Geologica Sinica(English Edition)2015，89，2： | 2 |
| 12 | Study on universal blade rotor for rototilling and stubble-breaking machine 显示文摘 | Jia Honglei Ma Chenglin Tong Jin | 2007 | Soil and Tillage Research2007，94，1： | 1 |
| 13 | Hierarchically Designed SiOx/SiOy Bilayer Nanomembranes as Stable Anodes for Lithium Ion Batteries显示文摘 | Lin Zhang Junwen Deng Lifeng Liu Wenping Si Steffen Oswald Lixia Xi Manab Kundu Guozhi Ma Thomas Gemming Stefan Baunack Fei Ding Chenglin Yan Oliver G. Schmidt | 2014 | Adv Mater2014，，26： | 1 |
| 14 | Study on universal blade rotor for rototilling and stubble-breaking machine显示文摘 | Jia Honglei Ma Chenglin Tong Jin | 2007 | Soil & Tillage Research2007，94，1： | 1 |
| 15 | Study on universal blade rotor for rototilling and stubble-breaking machine显示文摘 | Jia Honglei Ma Chenglin Tong Jin | 2007 | Soil & Tillage Research2007，94，1： | 1 |
| 16 | Effect of equal channel angular pressing and heat treatment on the microstructure of Cu-Al-Be-B shape memory alloy显示文摘 | Zhang Ping Ma Aibin Lu Sheng Chenglin Chu | 2009 | Materials Letters2009，63，： | 1 |
| 17 | Food safety assurance systems in China显示文摘 | Li Bai Chenglin Ma Shunlong Gong Yinsheng Yang | 2007 | Food Control2007，，18： | 1 |
| 18 | Development of Measuring System of Plant Electrical Potential and Its Application显示文摘Based on the characters of plant potentials, it introduced the construction and technology in developing the measuring system of plant electrical potentials, the input impedance of the amplifier must be enough high(= 1010~ 1012Ω) in order to measuring the plant weak signals and ensuring high common mode rejection ratio (CMRR). And wavelet transform was applied in denoising based on cross-validation (CV)threshold value. the experiment showed that this system could effectively detect the change of plant potentials,four-week old cucumber was stimulated by heat wounding, the variation potential (VP) and action potential(AP) would be evoked, the AP's varying amplitude can reach 40mV; the AP changed very fast, its duration time is about 0.01~0.02s and its amplitude often change from 15μV~5mV. | Yu Haiye Li Guochen Ma Chenglin | 2005 | 仪器仪表学报2005，26，z1： | 1 |
| 19 | Study on universal blade rotor for rototilling and stubble-breaking machine显示文摘 | Jia Honglei Ma chenglin Tong Jin | 2007 | Soil and Tillage Research2007，94，1： | 1 |
| 20 | Combined rototilling-stubble-breaking-planting machine显示文摘 | Jia Honglei Ma chenglin Li Guangyu | 2007 | Soil and Tillage Research2007，96，12： | 1 |
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