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| 1 | Sini powder ameliorates the inflammatory response in rats with stress-induced non-alcoholic fatty liver disease by inhibiting the nuclear factor kappa-B/pyrin domain-containing protein 3 pathway显示文摘OBJECTIVE: To evaluate the effectiveness of Sini powder for the treatment of non-alcoholic fatty liver disease(NAFLD) in rats and the molecular mechanisms involved.METHODS: A rat model of stress-induced NAFLD was established by a combination of long-term tethering and feeding of a high-fat, high-calorie diet. These rats were then intragastrically administered with either simvastatin, Sini powder, or vehicle for 1 week. The body mass and field test scores for each group were recorded weekly. Serum aspartate aminotransferase and alanine aminotransferase activities, and triglyceride, total cholesterol,and free fatty acid concentrations were measured.Liver tissue histopathology was examined on hematoxylin and eosin-stained paraffin sections and oil red O-stained frozen sections. The hepatic m RNA expression of nuclear factor kappa-B(NF-κB),NOD-, LRR-, and pyrin domain-containing protein 3(NLRP3), apoptosis-associated speck-like protein containing CARD(ASC), and caspase-1 were measured by reverse transcription-polymerase chain reaction(RT-PCR). The hepatic protein concentrations of NF-κB and NLRP3, ASC, caspase-1, interleukin-1β(IL-1β), interleukin-6(IL-6), and the serum concentrations of IL-1β and IL-6 were measured by enzyme-linked immunosorbent assay.RESULTS: Compared with the Blank group, rats in the Compound model group showed significant pathologic manifestations of NAFLD, and the expression of NF-κB, NLRP3, ASC, caspase-1, IL-1βand IL-6 were significantly higher(all P < 0.01). Both simvastatin and Sini powder significantly ameliorated the NAFLD pathology and the abnormal expression of NF-κB, NLRP3, ASC, caspase-1, IL-1β, and IL-6(all P < 0.01).CONCLUSION: Sini powder inhibits the inflamma-tory response in rats with NAFLD, which is mediated by NF-κB/NLRP3, IL-1β, and IL-6, reduces the effects of psychological stress, and improves lipid metabolism. Therefore, Sini powder may be effective for the treatment of stress-related NAFLD through multiple mechanisms. | Mu Jie Cheng Fafeng Wang Qingguo Wang Xueqian Zhu Wenxiang Ma Chongyang Yin Xiangjun Ren Beida Lian Yajun Du Xin Zhang Haixia Liu Shuling Zhang Shuang | 2020 | Journal of Traditional Chinese Medicine2020，40，2： | 9 |
| 2 | Microcalcifi cation detection using fuzzy logic and scale space ap proaches显示文摘 | Cheng H D Wang Jingli Shi Xiangjun | 2004 | Pattern Recognition2004，，37： | 1 |
| 3 | Contrast Enhancement Based on a Novel Homogeneity Measurement显示文摘 | Cheng Hengda Xue Mei Shi Xiangjun | 2003 | Pattern Recognition2003，36，11： | 1 |
| 4 | Influence of the injected water on gas outburst disasters in coal mine显示文摘 | Chen Xiangjun Cheng Yuanping | 2015 | Natural Hazards2015，76，2： | 1 |
| 5 | Impact of injected water on the gas desorption index of drill cuttings显示文摘 | Chen Xiangjun Cheng Yuanping | 2013 | Disaster Advances2013，6，7： | 1 |
| 6 | Microcalcification Detection Using Fuzzy Logic and Scale Space Approaches显示文摘 | CHENG H D WANG Jingli SHI Xiangjun | 2004 | Pattern Recognition2004，，8： | 1 |
| 7 | Comparing of Aviation Network Structure of Mid-south,Northwest and Southwest of China Based on Hierarchical Index Model显示文摘In order to compare the aviation network of mid-south,northwest and southwest of China to reveal the structure similarity and difference for providing quantitative evidence to construct regional aviation network and improve its structure,hierarchical index model of regional aviation network was established through dividing the aviation network into layers to research its structure characters.Data matrixes were defined to record the basic state of regional aviation network.Index matrixes were constructed to describe the quantitative features of regional aviation network.On the basis of these indexes,several structure indexes of all layers of aviation network were calculated to show the structure features of aviation network,such as ratio of passenger volume within the region with across the region,share rate of passenger volume among layers,ratio of average number of airline for each airport,ratio of average passenger volume for each airline and ratio of airline rate.According to the statistical data,similar structure of share rate of passenger volume among layers and average passenger volume for each airline in their regional aviation network was found after calculating.But on the side of ratio of passenger volume within the region with across the region,ratio of average number of airlines for each airport and ratio of airline rate were different. | Cheng Xiangjun Yang Fang Xie Li | 2020 | Journal of Traffic and Transportation Engineering2020，8，1： | 1 |
| 8 | System of Multigrid Nonlinear Least-squares Four-dimensional Variational Data Assimilation for Numerical Weather Prediction(SNAP):System Formulation and Preliminary Evaluation显示文摘A new forecasting system-the System of Multigrid Nonlinear Least-squares Four-dimensional Variational(NLS-4DVar)Data Assimilation for Numerical Weather Prediction(SNAP)-was established by building upon the multigrid NLS-4DVar data assimilation scheme,the operational Gridpoint Statistical Interpolation(GSI)−based data-processing and observation operators,and the widely used Weather Research and Forecasting numerical model.Drawing upon lessons learned from the superiority of the operational GSI analysis system,for its various observation operators and the ability to assimilate multiple-source observations,SNAP adopts GSI-based data-processing and observation operator modules to compute the observation innovations.The multigrid NLS-4DVar assimilation framework is used for the analysis,which can adequately correct errors from large to small scales and accelerate iteration solutions.The analysis variables are model state variables,rather than the control variables adopted in the conventional 4DVar system.Currently,we have achieved the assimilation of conventional observations,and we will continue to improve the assimilation of radar and satellite observations in the future.SNAP was evaluated by case evaluation experiments and one-week cycling assimilation experiments.In the case evaluation experiments,two six-hour time windows were established for assimilation experiments and precipitation forecasts were verified against hourly precipitation observations from more than 2400 national observation sites.This showed that SNAP can absorb observations and improve the initial field,thereby improving the precipitation forecast.In the one-week cycling assimilation experiments,six-hourly assimilation cycles were run in one week.SNAP produced slightly lower forecast RMSEs than the GSI 4DEnVar(Four-dimensional Ensemble Variational)as a whole and the threat scores of precipitation forecasts initialized from the analysis of SNAP were higher than those obtained from the analysis of GSI 4DEnVar. | Hongqin ZHANG Xiangjun TIAN Wei CHENG Lipeng JIANG | 2020 | Advances in Atmospheric Sciences2020，37，11： | 1 |
| 9 | Nonlinear Relationship and Its Evolutionary Trace between Node Degree and Average Path Length of China Aviation Network Based on Complex Network显示文摘In order to reveal the complex network characteristics and evolution principle of China aviation network,the relationship between the node degree and the average path length of China aviation network in 1988,1994,2001,2008 and 2015 was studied.According to the theory and method of complex network,the network system was constructed with the city where the airport was located as the network node and the airline as the edge of the network.On the basis of the statistical data,the node average path length of China aviation network in 1988,1994,2001,2008 and 2015 was calculated.Through regression analysis,it was found that the node degree had a logarithmic relationship with the average length of node path,and the two parameters of the logarithmic relationship had linear evolutionary trace.Key word:China aviation network,complex network,node degree,average length of node path,logarithmic relationship,evolutionary trace. | Cheng Xiangjun Zhang Xiaoxuan Li Yangqi | 2024 | Journal of Traffic and Transportation Engineering2024，12，1： | 0 |
| 10 | Nonlinear Relationship and Its Evolutionary Trace between Node Degree and Nearest Neighbor Average Degree of China Aviation Network Based on Complex Network显示文摘In order to reveal the complex network characteristics and evolution principle of China aviation network, the relationship between the node degree and the nearest neighbor average degree and its evolution trace of China aviation network in 1988, 1994, 2001, 2008 and 2015 were studied. According to the theory and method of complex network, the network system was constructed with the city where the airport was located as the network node and the airline as the edge of the network. According to the statistical data, the node nearest neighbor average degree of China aviation network in 1988, 1994, 2001, 2008 and 2015 was calculated. Through regression analysis, it was found that the node degree had a negative exponential relationship with the nearest neighbor average degree, and the two parameters of the negative exponential relationship had linear evolution trace. | Cheng Xiangjun Zhang Chunyue Zhang Xiaoxuan | 2023 | Journal of Traffic and Transportation Engineering2023，11，4： | 0 |
| 11 | Probability Distribution of Average Length of Node Path and Its Evolution Trace of Aviation Network of China Based on Complex Network显示文摘In order to reveal the complex network feature and its evolution principle of aviation network of China,probability distribution and its evolution trace of average length of node path of aviation network of China were researched according to statistics data in years 1988,1994,2001,2008 and 2015 of civil aviation of China.Floyd algorithm to calculate the path length between any two nodes of network was applied and average length of node path of aviation network was obtained according to this algorithm.It was discovered that average length of node path to other nodes had normal distribution function in each year.At meantime,the location parameter and scale parameter of normal distribution function had linear evolution trace.Airline rate was an index to describe the density of airline.It was found that average length of node path of aviation network of China evolved synchronously with airline rate and they had linear relationship. | Cheng Xiangjun Yang Fang Li Tao | 2021 | Journal of Traffic and Transportation Engineering2021，9，2： | 0 |
| 12 | Probability Distribution and Their Non-linear Relationship between Node Degree and Clustering Coefficient of Aviation Network of China Based on Complex Network显示文摘In order to reveal the complex network feature of aviation network of China,probability distribution of node degree and clustering coefficient of aviation network of China was researched according to statistics data of civil aviation of China.It was verified that node degree had power function probability distribution.Clustering coefficient of nodes with exponential function probability distribution was discovered.It was found that node degree and clustering coefficient had single peak nonlinear relationship.At the left side of the peak,there is no certain relationship between them.At the right side of the peak,clustering coefficient became smaller with the rise of node degree and there was negative exponential function relationship between them by regression analysis. | Cheng Xiangjun Yu Aihui Chen Xumei | 2020 | Journal of Traffic and Transportation Engineering2020，8，2： | 0 |
| 13 | Probability Distribution of China Aviation Network Average Degree of Edge Vertices and Its Evolutionary Trace Based on Complex Network显示文摘In order to reveal the complex network characteristics and evolution principle of China aviation network, the probability distribution and evolution trace of average degree of edge vertices of China aviation network were studied based on the statistics data of China civil aviation network in 1988, 1994, 2001, 2008 and 2015. According to the theory and method of complex network, the network system was constructed with the city where the airport was located as the network node and the route between cities as the edge of the network. Based on the statistical data, the average degrees of edge vertices in China aviation network in 1988, 1994, 2001, 2008 and 2015 were calculated. Using the probability statistical analysis method and regression analysis approach, it was found that the average degree of edge vertices had the probability distribution of normal function and the position parameters and scale parameters of the probability distribution had linear evolution trace. | Cheng Xiangjun Zhang Chunyue Liang Yanping | 2024 | Journal of Traffic and Transportation Engineering2024，12，2： | 0 |
| 14 | Analysis on the Epidemiological Characteristics of Escherichia coli O157:H7 Infection in Xuzhou,Jiangsu,China,1999显示文摘Objective:To determine epidemiologic features of an Escherichia coli O157:H7 outbreak occurred in Xuzhou,Jiangsu Province,China in 1999,and assess the incidence of E. coli O157:H7 in diarrhea patients and host animals and its relationship with disease onset,and provide a scientific basis for establishing prevention and control strategies. Methods: Epidemiological,microbiological,and molecular methods were performed to identify risk factors and describe the ecology of E. coli O157:H7 in the environment. Results: From May to September,in 1999,99 cases of E. coli O157:H7 infection were confirmed. Fifty-six patients were enrolled in the case-control study. Bad personal health habits and poor sanitary conditions in the kitchen were associated with increased risks of infection,whereas hand washing was protective. The household survey indicated that residents in the epidemic region during the outbreak had higher than expected rates of diarrhea. The total E. coli O157:H7 carrier rate in the livestock was 12.36%(22/178),specifically 19.15% in cattle,12.50% in goat,and 11.11% in swine. Numerical analysis of pulsed-field gel electrophoresis(PFGE) profiles divided strains into two clusters with 77.5% homology. One cluster contained 11 strains isolated from diarrheal patients,foods,and animals. The other cluster comprised 10 strains from patients and environment. Conclusion: In a large outbreak of E. coli O157:H7 infection among predominantly elderly residents in Xuzhou,high rates of carriage of E. coli O157: H7 among host animals most likely resulted in contamination of the environment,thereby leading to the outbreak. Effective and preventive control measures should be taken to avoid contamination,including environmental and family health improvement,good personal hygiene,and safe food handling practices. | Yefei Zhu Ling Gu Jiaxi Yu Jingchuan Yang Xiangjun Zhai Cheng Dong Huimin Qian Zhongming Tan Hongxing Pan Jiabin Liu Fengcai Zhu Hua Wang | 2009 | Journal of Nanjing Medical University2009，23，1： | 0 |
| 15 | Probability Distribution of China Aviation Network Nearest Neighbor Average Degree and Its Evolutionary Trace Based on Complex Network显示文摘In order to reveal the complex network characteristics and evolution principle of China aviation network,the probability distribution and evolution trace of node nearest neighbor average degree of China aviation network were studied based on the statistics data of China civil aviation network in 1988,1994,2001,2008 and 2015.According to the theory and method of complex network,the network system was constructed with the city where the airport was located as the network node and the route between cities as the edge of the network.Based on the statistical data,the nearest neighbor average degrees of nodes in China aviation network in 1988,1994,2001,2008 and 2015 were calculated.Using the probability statistical analysis method,it was found that the nearest neighbor average degree had the probability distribution of normal function and the position parameters and scale parameters of the probability distribution had linear evolution trace. | Cheng Xiangjun Zhang Chunyue Guo Jianyuan | 2023 | Journal of Traffic and Transportation Engineering2023，11，3： | 0 |
| 16 | Probability Distribution of Edge in Adjacent Matrix of Aviation Network of China and Algorithm of Searching Non-overlap Community Structure Based on Complex Network显示文摘In order to discover the probability distribution feature of edge in aviation network adjacent matrix of China and on the basis of this feature to establish an algorithm of searching non-overlap community structure in network to reveal the inner principle of complex network with the feature of small world in aspect of adjacent matrix and community structure,aviation network adjacent matrix of China was transformed according to the node rank and the matrix was arranged on the basis of ascending node rank with the center point as original point.Adjacent probability from the original point to extension around in approximate area was calculated.Through fitting probability distribution curve,power function of probability distribution of edge in adjacent matrix arranged by ascending node rank was found.According to the feature of adjacent probability distribution,deleting step by step with node rank ascending algorithm was set up to search non-overlap community structure in network and the flow chart of algorithm was given.A non-overlap community structure with 10 different scale communities in aviation network of China was found by the computer program written on the basis of this algorithm. | Cheng Xiangjun Yang Fang Wei Chong | 2021 | Journal of Traffic and Transportation Engineering2021，9，1： | 0 |
| 17 | Structure Evolution of China Aviation Network Based on Hierarchical Model显示文摘The annual passenger volume of airport reflected its passenger transport scale and the role in aviation network.The airports in whole country were divided into three layers:first layer airports,second layer airports and third layer airports.The airlines from the first layer airports consisted the first layer aviation network.The airlines from the second layer airports consisted the second layer aviation network.The airlines from the third layer airports consisted the third layer aviation network.The structure and function of different layer aviation network had significant differences.These differences were shown in the number of airlines,average number of airlines of each airport,annual passenger volume of airport and average passenger volume of each airline.National aviation network hierarchical model was constructed to describe the whole country aviation network.The matrix was built to describe the airline number,annual passenger volume,average number of airlines,average passenger volume of each airport and airline rate of aviation network.The index of national aviation network structure was constructed to show the ratio of index between different aviation network layer to describe the aviation network structure.The structure index was built to illustrate the macrostructural features of national aviation network.The statistics data in year 1988,1994,2001,2008 and 2015 of China aviation network were analyzed and basic data matrixes,basic index matrixes and structure index matrixes were calculated.The trend of ratio of corresponding index between the first layer and the second layer showed the change of basic structure of China aviation network.At meantime,the tendency of ratio of corresponding index between the third layer and the second layer also showed the change of basic structure.The trend of network general structure index illustrated that the large scaled new airports and airlines construction had significant influence on the national aviation network structure. | Cheng Xiangjun Chen Xumei Li Tao | 2022 | Journal of Traffic and Transportation Engineering2022，10，3： | 0 |
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