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| 1 | 华南早三叠世错时相沉积及其对复苏期生态系的启示显示文摘二叠纪末的大灭绝不仅重创了古生代海洋生态系,也使得海洋沉积体系发生剧变,导致灭绝之后早三叠世生物复苏期异常的生态系状况和海洋环境.丰富的特殊沉积物及相关沉积构造的广泛出现是早三叠世沉积的显著特征,如扁平砾石砾岩、蠕虫状灰岩、潮下皱纹构造、微生物岩、海底碳酸盐胶结岩扇、薄层灰岩和条带灰岩等.这些特征性的沉积物在奥陶纪之前的海洋环境中曾广泛分布,但在奥陶纪后生动物大发展之后,它们一般仅见于某些极端和异常的环境中.当它们在早三叠世正常浅海环境再次广泛出现时,被认为在时间上或环境上发生了错位,故被称为错时相(anachronistic facies).研究这些特殊沉积构造,对于探索古生代-中生代地质突变期异常的生态系状况和特殊的海洋环境具有重要作用.错时相在中国南方各地的早三叠世地层中广泛存在,分布于下三叠统众多层位中,而且囊括了全球已报道的大多数错时相沉积物,为研究华南早三叠世的海洋环境状况及其与生物复苏的关系提供了契机.'蠕虫状灰岩'是华南下三叠统中最典型、最发育的错时相沉积物,但对其研究相对较少.以湖北三峡地区的蠕虫状灰岩为例,对其类型划分、时空分布进行了重点论述.华南下三叠统中蠕虫状灰岩及其他错时相沉积构造的研究表明:错时相紧接生物大灭绝后出现,并随中生代海洋生态系的重建而退出正常浅海环境,这种耦合关系正是沉积体系和生态系对古生代-中生代地质突变及其导致的'特异'环境的自然响应.因此,错时相的盛衰变化可以作为独立于化石记录分析之外的生态变化指针. | 赵小明 童金南 姚华舟 张克信 Zhongqiang Chen | 2008 | 中国科学(D辑)2008，38，12： | 25 |
| 2 | Loss of 5-hydroxymethylcytosine is linked to gene body hypermethylation in kidney cancer显示文摘5-methylcytosine (5mC ) 和它的氧化形式 5-hydroxymethylcytosine (5hmC ) 被建议了涉及 tumorigenesis。因为印射方法的广泛地使用的 5mC 的读出,定序的重亚硫酸盐(BS-seq ) ,是 5mC 的和, 5hmC 层次, 5mC/5hmC 模式和这二修正的关系仍然保持糟糕理解。由介绍真实 5mC (BS-seq 由帮助 Tet 的 BS-seq 改正了, TAB-seq ) 并且 5hmC (TAB-seq ) 在单个核苷酸的分辨率同时铺平,我们这里证明与匹配的正常纸巾相比没有在肾肿瘤的 5mC 的全球损失。相反地, 5hmC 全球性被失去在几乎所有肾肿瘤纸巾。在肿瘤纸巾的 5hmC 水平是为肾癌症的一个独立预示的标记,与与更短的全面幸存联系的 5hmC 的底层。而且,我们证明 5hmC 的损失与匹配的正常纸巾相比在肿瘤被连接到 hypermethylation,特别地在基因身体区域。惊人地,基因身体 hypermethylation 显著地与肿瘤相关的基因的 silencing 被联系。IDH1 的 Downregulation 作为在肾癌症位于 5hmC 损失下面的机制被识别。恢复 5hmC 层次稀释了肿瘤房间的侵略能力并且在一个异种皮移植模型压制了肿瘤生长。一起,我们的结果证明 5hmC 的损失在由改变 DNA methylation 模式的肾癌症是一个预示的标记和一个 oncogenic 事件。 | Ke Chen Jing Zhang Zhongqiang Guo Qin Ma Zhengzheng Xu Yuanyuan Zhou Ziying Xu Zhongwu Li Xiongjun- Ye Xuesong Li Bifeng Yuan Yuwen Ke Chuan He Liqun Zhou Jiang Liu WeiminCi | 2016 | Cell Research2016，26，1： | 10 |
| 3 | Detection of Salmonella and several common Salmonella serotypes in food by loop-mediated isothermal amplification method显示文摘Salmonella Choleraesuis,S.Enteritidis and S.Typhimurium are the main pathogens that contaminate animal products and cause human Salmonella food poisoning.To establish the loop-mediated isothermal amplification(LAMP)method for the rapid detection of Salmonella and 3 common Salmonella serotypes,inner and outer primer sets targeting Salmonella invE gene and 3 serotype-specific genes fliC,lygD and STM4495 were designed.The LAMP reaction conditions were optimized.The specificity of LAMP primers was identified by testing 10 different bacterial strains including S.Choleraesuis,S.Enteritidis and S.Typhimurium.Take S.Choleraesuis as example,the detection limit of LAMP assay was 1.33×10^1 CFU/mL for bacteria culture and 2.0×10^1 CFU/mL for simulated pork sample.The results show that LAMP is a rapid,sensitive and specific method for Salmonella detection and can be used for the rapid detection of Salmonella in food. | Zhongqiang Chen Ke Zhang Huan Yin Qi Li Lan Wang Zhiguo Liu | 2015 | Food Science and Human Wellness2015，4，2： | 8 |
| 4 | 声波激励的超小型纳机电系统磁电天线显示文摘当前的小型天线依赖于电磁波的谐振,因此天线的尺寸与电磁波波长相关。典型的天线尺寸大于波长的1/10,而进一步缩小天线尺寸在近十年来都是一个公开的挑战。介绍一种通过悬浮铁氧/压电薄膜异质结构的声波激励纳机械磁电天线。这种磁电天线通过其在声波谐振频率处的磁电效应接收和发射电磁波。磁电天线中的体声波激发铁磁薄膜的磁化振荡,产生电磁波的辐射;反之,天线感应电磁波的磁场,得到压电电压输出。这种磁电天线(尺寸仅为波长的千分之一)比现有小型天线的尺寸小1到2个数量级,但性能却没有降低,在便携式无线通信系统中具有很大的应用潜力。 | Tianxiang Nan Hwaider Lin Yuan Gao Alexei Matyushov Guoliang Yu Huaihao Chen Neville Sun Shengjun Wei Zhiguang Wang Menghui Li Xinjun Wang Amine Belkessam Rongdi Guo Brian Chen James Zhou Zhenyun Qian Yu Hui Matteo Rinaldi Michael E.McConney BrANDon M.Howe Zhongqiang Hu John G.Jones Gail J.Brown Nian Xiang Sun 张建强(翻译) 陈鼎鼎(审校) | 2017 | 通信对抗2017，36，4： | 8 |
| 5 | Composition of algal pigments in surface freshen layer after ice melt in the central Arctic显示文摘Seasonal meltwater input creates a thin freshen layer in surface seawater under ice,which largely shifts the algae assemblages.Our recent observation of photosynthetic pigments in the high Arctic showed that ice bottom and 5m of seawater under ice contained relatively high concentration of fucoxanthin,while chlorophyll b and lutein were the major diagnostic pigments in ice-water interface and 0 m of seawater under ice.Additionally,a notable change of dominant phytoplankton occurred in the top 5 m of seawater under ice,from chlorophytes-dominated at surface to diatoms-dominated at 5 m depth,which might attribute to the sharp salinity gradient(salinity from12.5 to 28.1) in the surface seawater under ice.Our results imply that phytoplankton community in surface layer under ice would become more chlorophytes in the future warming Arctic Ocean. | ZHUANG Yanpei JIN Haiyan GU Fan ZHANG Yang BAI Youcheng JI Zhongqiang LU Yong CHEN lianfang | 2017 | Acta Oceanologica Sinica2017，36，8： | 6 |
| 6 | Variations in organic carbon loading of surface sediments from the shelf to the slope of the Chukchi Sea,Arctic Ocean显示文摘The content of organic carbon(OC) normalized to the specific surface area(SSA) of sediment is widely used to trace variations in OC loading(OC/SSA).This study presents observations of OC/SSA of surface sediments collected in the Chukchi Sea,a typical Arctic marginal sea.Shelf sediments exhibit much higher OC/SSA values than slope sediments in the study area.Compared with OC/SSA values reported from the East Siberian Shelf and Mackenzie River,the slope sediments possess lower OC loading.This abrupt decrease in OC/SSA is mostly related to the lower primary production on slope as well as possible oxidization processes.The results of linear regression analysis between OC and SSA indicate a sedimentary source rock for the OC in the Chukchi Sea sediments.Moreover,shelf sediments with low SSA possess a larger rock OC fraction than slope sediments do.The dataset of the present study enables a more thorough understanding of regional OC cycling in the Chukchi Sea. | LI Zhongqiao WANG Xinyi JIN Haiyan JI Zhongqiang BAI Youcheng CHEN Jianfang | 2017 | Acta Oceanologica Sinica2017，36，8： | 6 |
| 7 | Sources and distribution of sedimentary organic matter along the northern Bering and Chukchi Seas显示文摘In this study, lignin-derived phenols were used to determine the sources and distribution of sedimentary organic matter along the northern Bering Sea and Chukchi Sea of the Arctic Ocean. The lignin parameter syringyl/vanillyl(S/V) and cinnamyl/vanillyl(C/V) ratios are used to indicate vegetation sources; and the ratios of vanillic acid/vanillin,(Ad/Al)v and syringic acid/syringaldehyde,(Ad/Al)s are used as indicators of lignin diagenesis. Results showed the predominance of woody gymnosperm signal at the easternmost location in the northern Bering Sea, a mixture of refractory non-woody angiosperm and fresher gymnosperm tissues in the Chukchi Sea, and signal of fresher woody gymnosperm tissues in the northernmost locations in the Chukchi Sea. The lignin materials showed gradual increase in decomposition stage during transport along the northern Bering Sea. Hydrodynamic sorting process, which is the retention of coarser materials nearshore and transportation of finer particles farther offshore, most probably occurred along the east coast of the northern Bering Sea. In Chukchi Sea, the non-woody angiosperm tissues could have originated from the Canadian Arctic and gymnosperm tissues could be from the Russian Arctic side. The fresher materials in the northernmost Chukchi Sea could have been transported here via the ice-rafting process.Detection of fresh lignin materials and the occurrence of lignin decomposition mean that this region could be sensitive to the impact of climate change. | Fanglu Xu Haiyan Jin Zhongqiang Ji Jianfang Chen Pei Sun Loh | 2017 | Journal of Environmental Sciences2017，29，2： | 4 |
| 8 | Decompression alone versus decompression with instrumented fusion for young patients with single-level lumbar disc herniation:a short-term prospective comparative study显示文摘 | Sun Zhuoran Li Weishi Chen Zhongqiang Guo Zhaoqing Qi Qiang Zeng Yan Sun Chuiguo | 2014 | Chinese Medical Journal2014，，11： | 3 |
| 9 | Polydopamine/poly(sulfobetaine methacrylate)Co-deposition coatings triggered by CuSO_(4)/H_(2)O_(2)on implants for improved surface hemocompatibility and antibacterial activity显示文摘Implanted biomaterials such as medical catheters are prone to be adhered by proteins,platelets and bacteria due to their surface hydrophobicity characteristics,and then induce related infections and thrombosis.Hence,the development of a versatile strategy to endow surfaces with antibacterial and antifouling functions is particularly significant for blood-contacting materials.In this work,CuSO_(4)/H_(2)O_(2)was used to trigger polydopamine(PDA)and poly-(sulfobetaine methacrylate)(PSBMA)co-deposition process to endow polyurethane(PU)antibacterial and antifouling surface(PU/PDA(Cu)/PSBMA).The zwitterions contained in the PU/PDA(Cu)/PSBMA coating can significantly improve surface wettability to reduce protein adsorption,thereby improving its blood compatibility.In addition,the copper ions released from the metal-phenolic networks(MPNs)imparted them more than 90%antibacterial activity against E.coli and S.aureus.Notably,PU/PDA(Cu)/PSBMA also exhibits excellent performance in vivo mouse catheter-related infections models.Thus,the PU/PDA(Cu)/PSBMA has great application potential for developing multifunctional surface coatings for blood-contacting materials so as to improve antibacterial and anticoagulant properties. | Zhongqiang Zhu Qiang Gao Ziyue Long Qiuyi Huo Yifan Ge Ntakirutimana Vianney Nishimwe Anodine Daliko Yongchun Meng Jia Qu Hao Chen Bailiang Wang | 2021 | Bioactive Materials2021，6，8： | 3 |
| 10 | Response of phytoplankton community to different water types in the western Arctic Ocean surface water based on pigment analysis in summer 2008显示文摘Nutrients and photosynthesis pigments were investigated in the western Arctic Ocean during the 3rd Chinese Arctic Research Expedition Cruise in summer 2008.The study area was divided into five provinces using the Kmeans clustering method based on the physical and chemical characteristics of the sea water,and to discuss the distribution of the phytoplankton community structure in these provinces.CHEMTAX software was performed using HPLC pigments to estimate the contributions of eight algal classes to the total chlorophyll a(TChl a).The results showed that on the Chukchi Shelf,the Pacific Ocean inflow mainly controlled the Chl a biomass and phytoplankton communities by nutrient concentrations.The high nutrient Anadyr Water and Bering Shelf Water(An W and BSW) controlled region have high Chl a levels and the diatom dominated community structure.In contrast,in the region occupied by low-nutrient like Alaska Coastal Water(ACW),the Chl a biomass was low,with pico-and nano-phytoplankton as dominated species,such as prasinophytes,chrysophytes and cryptophytes.However,over the off-shelf,the ice cover condition which would affect the physical and nutrient concentrations of the water masses,in consequence had a greater impact on the phytoplankton community structure.Diatom dominated in ice cover region and its contribution to Chl a biomass was up to 75%.In the region close to the Mendeleev Abyssal Plain(MAP),controlled by sea-ice melt water with relatively high salinity(MW-HS),higher nutrient and Chl a concentrations were found and the phytoplankton was dominated by pico-and nano-algae,while the diatom abundance reduced to 33%.In the southern Canada Basin,an ice-free basin(IfB) with the lowest nutrient concentrations and most freshened surface water,low Chl a biomass was a consequence of low nutrients.The ice retreating and a prolonged period of open ocean may not be beneficial to the carbon export efficiency due to reducing the Chl a biomass or intriguing smaller size algae growth. | JIN Haiyan ZHUANG Yanpei LI Hongliang CHEN lianfang GAO Shengquan JI Zhongqiang ZHANG Yang | 2017 | Acta Oceanologica Sinica2017，36，8： | 2 |
| 11 | Astronomical Dating of the Middle Miocene Hanjiang Formation in the Pearl River Mouth Basin,South China Sea显示文摘Langhian 年龄的 Hanjiang 形成(中间中新世) 在珍珠河嘴盆(PRMB ) ,华南海由三角形的 siliciclastic 和浅海的架组成焦化有韵律的引申,它形成盆的潜在的水库之一。在盆为勘探的烃和探索改进 stratigraphic 决定,现在的学习承担光谱高分辨率的自然 gamma 光线(NGR ) 的分析决定主导的频率部件并且测试 Milankovitch 轨道的信号是否在有韵律的继任被记录的记载得好的记录。分析结果显示领前(19 ka 和 23 ka ) 的轨道的周期,斜(41 ka ) ,和怪癖(100 ka 和 405 ka ) ,它在有韵律的引申继任为天文驾驶的气候变化提供充分证据。在 biochronological 限制以内,高分辨率的天体的 timescale 通过到地球的轨道的最近的天文计算的变化的 NGR 记录的天体的调节被构造。天文调节的 timescale 能被使用为在整个时期认出的地质的事件和 bioevents 计算天体的年龄。分别地,有孔虫目动物 Globorotalia peripheroronda 和 Globigerinoides sicanus 的第一 downhole 出现在 14.546 妈和 14.919 妈是过时的它与在华南海的更早的估计稍微不同。什么时候与全球海平面的变化相比制图,为基于微化石分布认出的序列的天体的估计有一样的结束时间但是不同开始时间。这可能由于在推迟了全球海平面的升起的效果的海面升降的上升附加的本地或地区性的构造活动。天体的 timescale 也为 Langhian 阶段解决 depositional 进化历史(中间中新世) 与一个变化,那强烈类似于从 13.65 妈预言到 15.97 妈的地球的轨道的怪癖的。我们推断在 Hanjiang 形成控制沉积率的可变性的主要因素与 405-ka-period 怪癖有关。 | TIAN Shifeng CHEN Zhongqiang GAO Changhai ZHA Ming | 2013 | Acta Geologica Sinica(English Edition)2013，87，1： | 2 |
| 12 | Hydrogen Bonding-Assisted Synthesis of Silica/Oxidized Mesocarbon Microbeads Encapsulated in Amorphous Carbon as Stable Anode for Optimized/Enhanced Lithium Storage显示文摘The practical application of silica-based composites as an alternative to commercial graphite anode materials is hampered by their large volumetric expansion,poor conductivity,and low Coulombic efficiency.In this work,a novel silica/oxidized mesocarbon microbead/amorphous carbon(SiO2/O’MCMB/C)hierarchical structure in which SiO2 is sandwiched between spherical graphite and amorphous carbon shell was succes sfully fabricated through hydrogen bonding-assisted self-assembly and post-carbon coating method.The obtained three-layer hierarchical structure effectively accommodates the volumetric expansion of SiO2 and significantly enhances the electronic conductivity of composite materials.Moreover,the outer layer of amorphous carbon effectively increases the diffusion rate of lithium ions and promotes the formation of stable SEI film.As a result,the SiO2/O’MCMB/C composite exhibits superior electrochemical performance with a reversible capacity of 459.5 mA h/g in the first cycle,and the corresponding Coulombic efficiency is 62.8%.After 300 cycles,the capacity climbs to around 600 mA h/g.This synthetic route provides an efficient method for preparing SiO2 supported on graphite with excellent electrochemical performance,which is likely to promote its commercial applications. | Zongjie Cao Huitian Liu Wenlong Huang Peng Chen Yuansheng Liu Yu Yu Zhongqiang Shan Shuxian Meng | 2020 | Transactions of Tianjin University2020，26，1： | 2 |
| 13 | A negative carbon isotope anomaly associated with the earliest Lopingian (Late Permian) mass extinction显示文摘 | Kaiho K Chen Zhongqiang Ohashi T | 2005 | Palaeogeography Palaeoclimatology Palaeoecology2005，223，12： | 1 |
| 14 | A Writable Polypeptide–DNA Hydrogel with Rationally Designed Multi‐modification Sites显示文摘 | Chuang Li Ping Chen Yu Shao Xu Zhou Yuzhou Wu Zhongqiang Yang Zhibo Li Tanja Weil Dongsheng Liu | 2015 | Small2015，，9： | 1 |
| 15 | Comparison between two types of"Scheuermann disease-like people": thoracolumbar disc herniation patients and healthy volunteers with radiological signs of Scheuermann's disease显示文摘 | Guo Xinhu Chen Zhongqiang Liu Ning Guo Zhaoqing Qi Qiang Li Weishi Zeng Yan Sun Chuiguo | 2014 | Chinese Medical Journal2014，，22： | 1 |
| 16 | Rapid Formation of a Supramolecular Polypeptide–DNA Hydrogel for In Situ Three‐Dimensional Multilayer Bioprinting显示文摘 | Chuang Li Alan Faulkner‐Jones Alison R. Dun Juan Jin Ping Chen Yongzheng Xing Zhongqiang Yang Zhibo Li Wenmiao Shu Dongsheng Liu Rory R. Duncan | 2015 | Angew. Chem. Int. Ed2015，，13： | 1 |
| 17 | Effect of the Decompressive Extent on the Magnitude of the Spinal Cord Shift after Expansive Open-door Laminoplasty显示文摘 | Qingquan Kong Li Zhang Limin Liu Tao Li Quan Gong Jiancheng Zeng Yueming Song Hao Liu Shaobo Wang Yu Sun Fengshan Zhang Mai Li Zhongqiang Chen | 2011 | Spine2011，，13： | 1 |
| 18 | Tissue transglu- taminase expression and activity in human ligamentum flavum cells de- rived from thoracic ossification of ligamentum flavum显示文摘 | YIN Xiaoxue CHEN Zhongqiang GUO Zhaoqing | 2010 | Spine2010，35，20： | 1 |
| 19 | A brief survey of program slicing显示文摘 | Baowen Xu Ju Qian Xiaofang Zhang Zhongqiang Wu Lin Chen | 2005 | ACM SIGSOFT Software Engineering Notes2005，，2： | 1 |
| 20 | Detection of pancreatic cancer by indocyanine green-assisted fluorescence imaging in the first and second near-infrared windows显示文摘Dear Editor,In the United States,pancreatic cancer is considered the fourth most common reason for cancer-related deaths;over 53%of patients are diagnosed at end-stage with a 5-year survival rate of less than 3%[1].Incomplete removal of all cancerous cells generally leads to local recurrence of pancreatic cancer[2].Thus,the detection of tumor margin status plays an essential role in the complete resection of pancreatic cancer.Most of the existing imaging modalities,like computed tomography and magnetic resonance imaging,are primarily used for preoperative planning;these modalities also have issues of bulky equipment,radiation concerns,and slow imaging speed[2].Thus,these modalities can neither provide an intraoperative diagnosis of cancer with high sensitivity and specificity nor be used to define tumor margins[3]. | Zhongqiang Li Zheng Li Alexandra Ramos J.Philip Boudreaux Ramcharan Thiagarajan Yvette Bren Mattison Michael E.Dunham Andrew J McWhorter Qing Chen Jian Zhang Ji-Ming Feng Yanping Li Shaomian Yao Jian Xu | 2021 | Cancer Communications2021，41，12： | 1 |
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