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| 1 | Depositional environment in the southern Ulleung Basin,East Sea(Sea of Japan),during the last 48000 years显示文摘The present study is based on the sedimentological data from a piston core KCES1 off the southern Ulleung Basin margin,the East Sea(Sea of Japan).The data include sediment color(L*),X-ray radiographs,grain size distribution and AMS14C date.Four kinds of sediments(homogeneous,laminated,crudely laminated and hybrid sediments) are identified according to the characters of the sedimentary structures that were considered to reflect changes in bottom-water oxygenation.Alternations of dark laminated/crudely laminated sediments and light homogeneous sediments represent millennial-scale variations that are possibly associated with the high-resolution changes in the East Asian monsoon(EAM).The relative contributions of the East China Sea Coastal Water(ECSCW) and the Tsushima Warm Current(TWC) were likely the main reasons for the repetition of the anoxic and oxic depositional conditions in the East Sea since the last 48 ka BP.During the interstadial,the strengthen summer EAM was attributed to the expansion of the ECSCW because of more humid climate in central Asia,and then more strongly low-salinity,nutrient-enriched water was introduced into the East Sea.The ventilation of deep water was restricted and therefore the dark laminated layer deposited under the anoxic bottom water condition.During the lowest stand of sea level in the last glacial maximum(LGM),the isolated East Sea dominated by stratified water masses and the euxinic depositional environment formed.The homogenous sediments have been predominating since 17.5 ka BP indicating that the TWC has intruded into the East Sea gradually with the stepwise rise of sea level and the bottom water oxygen level was high.During the late Younger Dryas(YD) period,the last dark laminated layer deposited because the ventilation of bottom water was restricted by stronger summer EAM.The TWC strengthened and the bottom water became oxic again from 10.5 ka BP. | LIU Yanguang SHA Longbin SHI Xuefa SUK Bong-Chool LI Chaoxin WANG Kunshan LI Xiaoyan | 2010 | Acta Oceanologica Sinica2010,29,5: | 4 |
| 2 | Multi-scale mechanotransduction of the poroelastic signals from osteon to osteocyte in bone tissue显示文摘In order to quantify the poroelastic mechanical signals conduction and evaluate the biomechanical effectiveness of functional units(osteocyte processes,canaliculi and lacuna)in lacunar-canalicular system(LCS),a multiscale poroelastic finite element model was established by using the Comsol Multiphysics software.The poroelastic mechanical signals(pore pressure,fluid velocity,von-Mises stress,strain)were analyzed inside the osteon-osteocyte system.The effects of osteocyte(OCY)’s shape(ellipse and circle),long axis directions(horizontal and vertical)and mechanical properties(Elastic modulus and permeability)on its poroelastic responses were examined.It is found that the OCY processes is the best mechanosensor compared with the OCY body,lacunae and canaliculi.The mechanotransduction ability of the elliptic shaped OCY is stronger than that of circular shaped.The pore pressure and flow velocity around OCYs increase as the elastic modulus and permeability of OCY increase.The established model can be used for studying the mechanism of bone mechanotransduction at the multiscale level. | Xiaogang Wu Chaoxin Li Kuijun Chen Yuqin Sun Weilun Yu Meizhen Zhang Yanqin Wang Yixian Qin Weiyi Chen | 2020 | Acta Mechanica Sinica2020,36,4: | 2 |
| 3 | Immunometabolism and potential targets in severe COVID-19 peripheral immune responses显示文摘In a recent single cell transcriptomic investigation of the peripheral immune responses of the patients with severe COVID-19[1],no substantial expression of pro-inflammatory cytokines has been identified in the peripheral monocytes and lymphocytes,while these peripheral immune cells exhibit phenotypes of heterogeneously expressed interferon-stimulated genes in certain COVID-19 patients.These genes may contribute to the inhibitory response to the viral entry,translation,replication and egress.Questions remain regarding why the peripheral cytokine production is constrained,what additional roles these peripheral immune cells may play in COVID-19 pathophysiology,and which potential targets can be explored for facilitating COVID-19 therapeutics. | Shanshan Wang Xian Zeng Yali Wang Yuzong Chen Chaoxin Wang Dongzhi Zhuoma Fengying Zhang Yufen Zhao | 2021 | Asian Journal of Pharmaceutical Sciences2021,16,6: | 1 |
| 4 | A fluid flow model in the lacunar-canalicular system under the pressure gradient and electrical field driven loads显示文摘The lacunar-canalicular system(LCS)is acknowledged to directly participate in bone tissue remodeling.The fluid flow in the LCS is synergic driven by the pressure gradient and electric field loads due to the electro-mechanical properties of bone.In this paper,an idealized annulus Maxwell fluid flow model in bone canaliculus is established,and the analytical solutions of the fluid velocity,the fluid shear stress,and the fluid flow rate are obtained.The results of the fluid flow under pressure gradient driven(PGD),electric field driven(EFD),and pressure-electricity synergic driven(P-ESD)patterns are compared and discussed.The effects of the diameter of canaliculi and osteocyte processes are evaluated.The results show that the P-ESD pattern can combine the regulatory advantages of single PGD and EFD patterns,and the osteocyte process surface can feel a relatively uniform shear stress distribution.As the bone canalicular inner radius increases,the produced shear stress under the PGD or P-ESD pattern increases slightly but changes little under the EFD pattern.The increase in the viscosity makes the flow slow down but does not affect the fluid shear stress(FSS)on the canalicular inner wall and osteocyte process surface.The increase in the high-valent ions does not affect the flow velocity and the flow rate,but the FSS on the canalicular inner wall and osteocyte process surface increases linearly.In this study,the results show that the shear stress sensed by the osteocyte process under the P-ESD pattern can be regulated by changing the pressure gradient and the intensity of electric field,as well as the parameters of the annulus fluid and the canaliculus size,which is helpful for the osteocyte mechanical responses.The established model provides a basis for the study of the mechanisms of electro-mechanical signals stimulating bone tissue(cells)growth. | Xiaogang WU Xiyu WANG Chaoxin LI Zhaowei WANG Yuqin SUN Yang YAN Yixian QIN Pengcui LI Yanqin WANG Xiaochun WEI Weiyi CHEN | 2022 | Applied Mathematics and Mechanics(English Edition)2022,43,6: | 0 |
| 5 | Study of the spatial growth of stimulated Brillouin scattering in a gas-filled hohlraum via detecting the driven ion acoustic wave显示文摘In an experiment performed on the Shenguang-III prototype laser facility, collective Thomson scattering (TS) is used to study the spatialgrowth of stimulated Brillouin scattering (SBS) in a gas-filled hohlraum by detecting the SBS-driven ion acoustic wave. High-quality timeresolved SBS and TS spectra are obtained simultaneously in the experiment, and these are analyzed by a steady-state code based on theray-tracing model. The analysis indicates that ion–ion collisions may play an important role in suppressing SBS growth in the Au plasma;as aresult, the SBS excited in the filled gas region is dominant. In the early phase of the laser pulse, SBS originates primarily from the high-densityplasma at the edges of the interaction beam channel, which is piled up by the heating of the interaction beam. Throughout the duration of thelaser pulse, the presence of the TS probe beam might mitigate SBS by perturbing the density distribution around the region overlapping withthe interaction beam. | Chaoxin Chen Tao Gong Zhichao Li Liang Hao Yonggang Liu Xiangming Liu Hang Zhao Yaoyuan Liu Kaiqiang Pan Qi Li Sanwei Li Zhijun Li Sai Jin Feng Wang Dong Yang | 2024 | Matter and Radiation at Extremes2024,9,2: | 0 |
| 6 | An amorphous FeMoO_(4) nanorod array enabled high-efficiency oxygen evolution electrocatalysis in alkaline seawater显示文摘The development of highly efficient and durable oxygen evolution reaction(OER)catalysts for seawater electrolysis is of great importance for applications.Here,an amorphous FeMoO_(4) nanorod array on Ni foam is reported as a highly active OER electrocatalyst in alkaline seawater,requiring only overpotentials of 303 and 332 mV to achieve 100 and 300 mA·cm^(-2),respectively.Moreover,it shows strong long-term electrochemical durability for at least 50 h. | Jie Tang Shengjun Sun Xun He Hui Zhang Chaoxin Yang Min Zhang Meng Yue Hefeng Wang Yuntong Sun Yonglan Luo Sulaiman Alfaifi Asmaa Farouk Mohamed S.Hamdy Xuping Sun Huiqing Wang Binwu Ying | 2024 | Nano Research2024,17,4: | 0 |
| 7 | The effect of pore size on the mechanical properties, biodegradation and osteogenic effects of additively manufactured magnesium scaffolds after high temperature oxidation: An in vitro and in vivo study显示文摘The effects of pore size in additively manufactured biodegradable porous magnesium on the mechanical properties and biodegradation of the scaffolds as well as new bone formation have rarely been reported. In this work, we found that high temperature oxidation improves the corrosion resistance of magnesium scaffold. And the effects of pore size on the mechanical characteristics and biodegradation of scaffolds, as well as new bone formation, were investigated using magnesium scaffolds with three different pore sizes, namely, 500, 800, and 1400 μm (P500, P800, and P1400). We discovered that the mechanical characteristics of the P500 group were much better than those of the other two groups. In vitro and in vivo investigations showed that WE43 magnesium alloy scaffolds supported the survival of mesenchymal stem cells and did not cause any local toxicity. Due to their larger specific surface area, the scaffolds in the P500 group released more magnesium ions within reasonable range and improved the osteogenic differentiation of bone mesenchymal stem cells compared with the other two scaffolds. In a rabbit femoral condyle defect model, the P500 group demonstrated unique performance in promoting new bone formation, indicating its great potential for use in bone defect regeneration therapy. | Chaoxin Wang Jinge Liu Shuyuan Min Yu Liu Bingchuan Liu Yuanyu Hu Zhengguang Wang Fengbiao Mao Caimei Wang Xiaolin Ma Peng Wen Yufeng Zheng Yun Tian | 2023 | Bioactive Materials2023,,10: | 0 |
| 8 | Enhancing the stability of Ni Fe-layered double hydroxide nanosheet array for alkaline seawater oxidation by Ce doping显示文摘Electrocatalytic hydrogen production from seawater holds enormous promise for clean energy generation.Nevertheless,the direct electrolysis of seawater encounters significant challenges due to poor anodic stability caused by detrimental chlorine chemistry.Herein,we present our recent discovery that the incorporation of Ce into Ni Fe layered double hydroxide nanosheet array on Ni foam(Ce-Ni Fe LDH/NF)emerges as a robust electrocatalyst for seawater oxidation.During the seawater oxidation process,CeO_(2)is generated,effectively repelling Cl^(-)and inhibiting the formation of Cl O-,resulting in a notable enhancement in the oxidation activity and stability of alkaline seawater.The prepared Ce-Ni Fe LDH/NF requires only overpotential of 390 m V to achieve the current density of 1 A cm^(-2),while maintaining long-term stability for 500 h,outperforming the performance of Ni Fe LDH/NF(430 m V,150 h)by a significant margin.This study highlights the effectiveness of a Ce-doping strategy in augmenting the activity and stability of materials based on Ni Fe LDH in seawater electrolysis for oxygen evolution. | Yongchao Yao Shengjun Sun Hui Zhang Zixiao Li Chaoxin Yang Zhengwei Cai Xun He Kai Dong Yonglan Luo Yan Wang Yuchun Ren Qian Liu Dongdong Zheng Weihua Zhuang Bo Tang Xuping Sun Wenchuang(Walter)Hu | 2024 | Journal of Energy Chemistry2024,91,4: | 0 |
| 9 | Mace-like TTF-TCNQ/HKUST-1 composite structures for rapid NO_(2) detection: Synergistically induced ultrahigh sensitivity and outstanding selectivity显示文摘Integration and synergy of the unique functions of different components have been developed into one of the most convenient and effective ways to construct the composite advanced materials with collective properties and improved performances.In this work,the mace-like tetrathiafulvalene-tetracyanoquinodimethane(TTF-TCNQ)/HKUST-1 composite structures with single single-crystalline TTF-TCNQ submicrorods covered by ordered HKUST-1 nanosheet arrays were successfully constructed by an efficient TTF-TCNQ seed-mediated growth approach.Impressively,thanks to the synergetic and complementary effects between TTF-TCNQ and HKUST-1,the sensors based on such mace-like TTF-TCNQ/HKUST-1 composite structures not only displayed an experimental detection limit of 10 part per billion(ppb)for NO_(2) detection,but also exhibited outstanding selectivity even if the concentration of the interfering gases was 10 times that of NO_(2).Meanwhile,good reproducibility and rapid response were also achieved.This work opens the avenue for creation of novel high-performance sensing materials for application in gas sensing. | Chaoxin Lin Kumchol Kim Zuochao Wang Zhuang Yan Zhiyong Tang Yaling Liu | 2023 | Nano Research2023,16,12: | 0 |