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| 1 | Distributed Adaptive Fault-Tolerant Output Regulation of Heterogeneous Multi-Agent Systems With Coupling Uncertainties and Actuator Faults显示文摘In this paper, we consider the distributed adaptive fault-tolerant output regulation problem for heterogeneous multiagent systems with matched system uncertainties and mismatched coupling uncertainties among subsystems under the influence of actuator faults. First, distributed finite-time observers are proposed for all subsystems to observe the state of the exosystem. Then, a novel fault-tolerant controller is designed to compensate for the influence of matched system uncertainties and actuator faults. By using the linear matrix inequality technique, a sufficient condition is provided to guarantee the solvability of the considered problem in the presence of mismatched coupling uncertainties. Moreover, it is shown that the system in closed-loop with the developed controller can achieve output regulation by using the Lyapunov stability theory and cyclic-small-gain theory.Finally, a numerical example is given to illustrate the effectiveness of the obtained result. | Chao Deng Weinan Gao Weiwei Che | 2020 | IEEE/CAA Journal of Automatica Sinica2020，7，4： | 6 |
| 2 | Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling显示文摘Glioblastoma(GBM)is a prevalent and highly lethal form of glioma,with rapid tumor progression and frequent recurrence.Excessive outgrowth of pericytes in GBM governs the ecology of the perivascular niche,but their function in mediating chemoresistance has not been fully explored.Herein,we uncovered that pericytes potentiate DNA damage repair(DDR)in GBM cells residing in the perivascular niche,which induces temozolomide(TMZ)chemoresistance.We found that increased pericyte proportion correlates with accelerated tumor recurrence and worse prognosis.Genetic depletion of pericytes in GBM xenografts enhances TMZ-induced cytotoxicity and prolongs survival of tumor-bearing mice.Mechanistically,C-C motif chemokine ligand 5(CCL5)secreted by pericytes activates C-C motif chemokine receptor 5(CCR5)on GBM cells to enable DNA-dependent protein kinase catalytic subunit(DNA-PKcs)-mediated DDR upon TMZ treatment.Disrupting CCL5-CCR5 paracrine signaling through the brain-penetrable CCR5 antagonist maraviroc(MVC)potently inhibits pericyte-promoted DDR and effectively improves the chemotherapeutic efficacy of TMZ.GBM patient-derived xenografts with high CCL5 expression benefit from combined treatment with TMZ and MVC.Our study reveals the role of pericytes as an extrinsic stimulator potentiating DDR signaling in GBM cells and suggests that targeting CCL5-CCR5 signaling could be an effective therapeutic strategy to improve chemotherapeutic efficacy against GBM. | Xiao-Ning Zhang Kai-Di Yang Cong Chen Zhi-Cheng He Qiang-Hu Wang Hua Feng Sheng-Qing Lv Yan Wang Min Mao Qing Liu Yao-Yao Tan Wen-Ying Wang Tian-Ran Li Lin-Rong Che Zhong-Yi Qin Ling-Xiang Wu Min Luo Chun-Hua Luo Yu-Qi Liu Wen Yin Chao Wang Hai-Tao Guo Qing-Rui Li Bin Wang Wei Chen Shuang Wang Yu Shi Xiu-Wu Bian Yi-Fang Ping | 2021 | Cell Research2021，31，10： | 5 |
| 3 | Hibernate Combined TableViewer in the Application of Medicines Inventory Management System显示文摘To solve the data persistence problem in the management system, this paper used the popular object-relational mapping framework Hibernate to achieve the persistence layer which in a medicines inventory management system. This paper described the advantages and principles of the Hibernate, and then showed the written work of the configuration files, mapping files, persistent classes, etc. Finally, the paper showed how to display the specific data information in the TableViewer based on the Eclipse RCP framework. It is observed that, operating the objects in the Hibernate framework is more flexible and efficient than using JDBC directly. Ad in addition, the application based on Eclipse RCP framework can take over many excellent features of Eclipse, and the developers can improve their efficiency by these features. | HONG Wen-qiang CHE Chao ZHANG Qiang WEI Xiao-peng | 2014 | Computer Aided Drafting,Design and Manufacturing2014，24，2： | 5 |
| 4 | A Facile Synthetic Method for (3Z,6Z,9S,10R)-9,10-Epoxy-3,6-heneicosadiene,Sex Pheromone Component of Hyphantria Cunea (Drug)显示文摘Total synthesis of (3Z, 6Z, 9S, 10R)-9, 10-epoxy-3, 6-heneicosadiene, sex pheromone component of Hyphantria cunea (Drug), was achieved using Sharpless AE kinetic resolution and alkylative epoxide rearrangement as key steps. | Chao CHE, Zhong Ning ZHANG StateKey Laboratory IntegratedManagementofInsectsandRodents,Institute of Zoology, Chinese Academy of Sciences, Beijing 100080 Graduate School of the Chinese Academy of Sciences, Beijing 100039 | 2005 | Chinese Chemical Letters2005，16，4： | 4 |
| 5 | The mutation network for the hemagglutinin gene from the novel influenza A (H1N1) virus显示文摘A mutation network for the hemagglutinin gene(HA) of the novel type A(H1N1) influenza virus was constructed.Sequence homology analysis indicated that one HA sequence type from the viruses mainly isolated from Mexico was likely the original type in this epidemic.Based on the 658A and 1408T mutations in HA,the viruses evolving into this epidemic were divided into three categories,the Mexico,the transitional and the New York type.The three groups of viruses presented distinctive clustering features in their geographic distributions. | HE YunGang DING GuoHui BIAN Chao HUANG Zhong LAN Ke SUN Bing WANG XueCai LI YiXue WANG HongYan WANG XiaoNing YANG Zhong ZHONG Yang JIN WeiRong XIONG Hui DAI JianXin GUO YaJun WANG Hao CHE XiaoYan WU Fan YUAN ZhenAn ZHANG Xi CAO ZhiWei ZHOU XiaoNong ZHOU JiaHai MA ZhiYong TONG GuangZhi ZHAO GuoPing JIN Li | 2009 | Chinese Science Bulletin2009，54，13： | 3 |
| 6 | Influence of fluvastatin on cardiac function and baroreflex sensitivity in diabetic rats显示文摘 | Fang XIE Chao SUN Li-hua SUN Jing-yuan LI Xin CHEN Hui CHE Guan-yi LU Bao-feng YANG Jing AI | 2011 | Acta Pharmacologica Sinica2011，32，3： | 3 |
| 7 | Adult metaplastic hutch diverticulum with robotic-assisted diverticulectomy and reconstruction:A case report显示文摘BACKGROUND Hutch diverticulum arises from the compromised muscular development at the ureteral orifice.It is a congenital disease and extremely rare in adult,only accounting for about 3%occurrence worldwide.It can be either symptomatic or asymptomatic,and relies on image tools for diagnosis and preoperative planning.Indications for surgery are dependent on the complications from the diverticulum.Metaplasia is about 10%among those with hutch diverticulum,and it still has chances turning into malignancy,especially urothelial cell carcinoma.CASE SUMMARY A 27-year-old man was presented with frequently recurrent urinary tract infection for one year,and had suffered from intermittent right flank pain for 3 mo.No past medical histories were recorded before.No obvious abnormalities on laboratory data and urine examination were found.Under ultrasound,right hydronephrosis was seen and an anatomical abnormality was observed on intravenous pyelography.Further computed tomography urogram showed one diverticulum seated at superolateral side of right ureteral orifice.Cystoscopy was done and biopsy results showed focal metaplasia.After discussing with him,roboticassisted diverticulectomy with reconstruction was performed.Right hydronephrosis was greatly improved after surgery.He has completed his 1.5-year follow-ups,and no malignancies were seen from urine cytology and image of intravenous pyelography.CONCLUSION Robotic-assisted diverticulectomy and reconstruction to hutch diverticulum is a safe and efficient operation,providing several advantages over open and laparoscopic ones. | Che H Yang Yi S Lin Yen C Ou Wei C Weng Li H Huang Chin H Lu Chao Y Hsu Min C Tung | 2020 | World Journal of Clinical Cases2020，8，20： | 2 |
| 8 | The silicothermic reduction of magnesium in flowing argon and numerical simulation of novel technology显示文摘The silicothermic reduction of magnesium was investigated by the non-isothermal thermoanalysis in flowing argon,while the traditional investigations of silicothermic process for magnesium reduction were carried out under vacuum conditions.Firstly,the thermal gravimetric(TG)and derivative thermogravimetric(DTG)characteristic of briquettes prepared with calcined dolomite,ferrosilicon and fluorite were characterized by the thermogravimetric analyzer(TGA)at different heating rates.The intrinsic chemical kinetic mechanism was identified as a formal chemical reaction with the Nth order type which showed apparent activation energy E and reaction order n were 290.168 kJ mol^(-1) and 1.076,respectively.Then,a novel technique of magnesium production without vacuum was put forward and a three-dimensional unsteady numerical model incorporating the chemical reaction,radiation,heat conduction and heat convection was established and simulated,which was verified by Pidgeon process and novel tech no logy.rIhe nu merical results showed that the cycle time of the novel technique could be reduced when the argon temperature was higher than 1343 K and the argon entrance velocity was over 0.05 m s^(-1).And the effect of the argon temperature on reduction degree was much larger than that of entrance velocity. | Yusi Che Chao Zhang Jianxun Song Xiaojia Shang Xiping Chen Jilin He | 2020 | Journal of Magnesium and Alloys2020，8，3： | 2 |
| 9 | Structure modeling and spatial epitope analysis for HA protein of the novel H1N1 influenza virus显示文摘In recent months,a novel influenza virus H1N1 broke out around the world.With bioinformatics technology,the 3D structure of HA protein was obtained,and the epitope residues were predicted with the method developed in our group for this novel flu virus.58 amino acids were identified as potential epitope residues,the majority of which clustered at the surface of the globular head of HA protein.Although it is located at the similar position,the epitope of HA protein for the novel H1N1 flu virus has obvious differences in the electrostatic potential compared to that of HA proteins from previous flu viruses. | WU Di XU TianLei SUN Jing DAI JianXin DING GuoHui HE YunGang ZHOU ZhengFeng XIONG Hui DONG Hui JIN WeiRong BIAN Chao JIN Li WANG HongYan WANG XiaoNing YANG Zhong ZHONG Yang WANG Hao CHE XiaoYan HUANG Zhong LAN Ke SUN Bing WU Fan YUAN ZhenAn ZHANG Xi ZHOU XiaoNong ZHOU JiaHai MA ZhiYong TONG GuangZhi GUO YaJun ZHAO GuoPing LI YiXue CAO ZhiWei | 2009 | Chinese Science Bulletin2009，54，13： | 2 |
| 10 | Feasibility of Intermediate Fluid Vaporizer with Spiral Wound Tubes显示文摘A novel intermediate fluid vaporization (IFV) technology for LNG re-gasification process with spiral-wound heat exchanging tubes is proposed. The new IFV project combines the advantage of running the shell and tube heat exchangers at high pressure with the advantage of compact space of heat exchangers. Thermal analysis on the two processes of forced convection and vaporization type heat transfer in the spiral wound tubes and vapor condensation /re-boiling type of heat transfer via intermediate fluid in shell side shows the feasibility of this promising technology. | Liu Fengxia Dai Yuqiang Wei Wei Zou Jiupeng Zhu Che Dong Chao Hu Dapeng | 2013 | China Petroleum Processing & Petrochemical Technology2013，15，1： | 2 |
| 11 | Realization of warm white light emitting in single phase Gd(P_(x)V_(1−x))O_(4):y at% Sm^(3+),1 at% Bi^(3+) phosphor显示文摘A series of single phase,warm white light emitting phosphors,Gd(P_(x)V_(1−x))O_(4):y at%Sm^(3+),with 1 at%Bi^(3+) doping concentration were synthesized by high temperature solid state method in this work.The experimental results indicate broadband cyan emission of Bi^(3+)and characteristic orange-red emission of Sm^(3+)can be effectively tuned by changing the ratios of PO^(3−)_(4)/VO^(3−)_(4) in Gd(P_(x)V_(1−x))O_(4):1 at%Sm^(3+),1 at%Bi^(3+),and the energy transfer process among VO^(3−)_(4),Sm^(3+),Bi^(3+) also can be adjusted.Based on this,warm white light emitting can be realized by further optimizing the doping concentration of Sm^(3+) in the phosphors.At 423 K,the PL intensity of Gd(P_(0.7)V_(0.3))O_(4):2 at%Sm^(3+),1 at%Bi^(3+) remains~84.3%of the initial value at 293 K,while the measured quantum efficiency is 67.8%.EL spectrum analysis results of the fabricated white light emitting diode(wLED)based on a 310 nm UV-chip and Gd(P_(0.7)V_(0.3))O4:2 at%Sm^(3+),1 at%Bi^(3+)phosphors imply low correlated color temperature(3132 K)and appropriate color-rending index(R_(a)=82.7).These results demonstrate that Gd(P_(0.7)V_(0.3))O4:2 at%Sm^(3+),1 at%Bi^(3+)is a good candidate for manufacturing UV-activated warm white light emitting diodes. | Chao Dou Yanzhen Yin Fei Zheng Zhen Wang Shijia Sun Chen Hu Yang Che Bing Teng Degao Zhong | 2022 | Journal of Rare Earths2022，40，4： | 2 |
| 12 | The Nature-Based Ecological Engineering Paradigm: Symbiosis, Coupling, and Coordination显示文摘1.Introduction We are currently facing three major ecological threats on a global scale:biodiversity loss,climate change,and environmental pollution exacerbation.The degradation of terrestrial and marine ecosystems poses a major risk to human survival and development,brings serious impacts to the wellbeing of 3.2 billion people,and causes the loss of about 10%of the annual global gross domestic product(GDP)[1,2].Meanwhile,the coronavirus disease 2019(COVID-19)epidemic is still spreading rapidly throughout the world,showing that the present relationship between humans and nature is unsustainable.It is necessary to protect nature so as to maintain the self-resilience of ecosystems. | Xiahui Wang Jinnan Wang Bo Wang Benjamin Burkhard Lulu Che Chao Dai Lijie Zheng | 2022 | Engineering2022，，12： | 2 |
| 13 | Epidermal thickness and biomechanical properties of plantar tissues in diabetic foot显示文摘 | Chao CYL Zheng YP Cheing GLY | 2011 | Ultrasound Med Biol2011，37，7： | 1 |
| 14 | Eight-year follow-up of locally advanced lymphoepithelioma-like carcinoma at upper urinary tract: A case report显示文摘BACKGROUND Urinary tract lymphoepithelioma-like carcinoma is rarely seen.Although it is termed after lymphoepithelioma at the nasopharynx,it behaves more like high grade urothelial carcinoma by immunohistochemical features.Most published literatures focused on its rarity but few discussed results of long-term follow-ups.As no available guidelines are applicable,we postulated that principles should be similar to that of urothelial carcinoma at urinary tract.As of now,this work features the longest follow-up of this cancer at the upper urinary tract.CASE SUMMARY A 63-year-old female had a chief complaint of intermittent left flank pain for 2 mo,along with accompanying symptoms including vomiting and body weight loss,about 7 kg over 2 mo.Laboratory data showed normocytic anemia,mildly poor renal function,and hyperparathyroidism.Urine analysis showed mild hematuria.Computed tomography showed a 4.2-cm-width irregular mass over left renal pelvic and enlarged lymph node at the left renal hilum.Whole-body bone scan was negative of active bone lesions.Biopsy from ureteroscopy showed urothelial carcinoma.Specimen from laparoscopic nephroureterectomy with bladder cuff resection showed lymphoepithelioma-like carcinoma with muscular invasion(pT3).She took adjuvant chemotherapies of 2 cycles and full courses of radiation therapy.No recurrence was observed with designed investigative programs.CONCLUSION Locally advanced urinary tract lymphoepithelioma-like carcinoma could benefit from nephroureterectomy and bladder cuff excision in terms of recurrence-free survival. | Che H Yang Wei C Weng Yi S Lin Li H Huang Chin H Lu Chao Y Hsu Yen C Ou Min C Tung | 2020 | World Journal of Clinical Cases2020，8，19： | 1 |
| 15 | Epidermal thickness and biomechanical properties of plantar tissues in diabetic foot 显示文摘 | Chao CY Zheng YP Cheing GL | 2011 | Ultra- sound Med Biol2011，37，7： | 1 |
| 16 | A new stretch forming process based on loading at discrete points and its numerical investigation显示文摘 | Cai Zhong-yi Wang Mi Che Chao jie | 2013 | Applied Mechanics and Materials2013，，： | 1 |
| 17 | The effects of lower-extremity functional electric stimulation on the orthostatic responses of people with tetraplegia显示文摘 | Chao YC Cheing LG | 2005 | Arch Phys Med Rehabil2005，86，7： | 1 |
| 18 | Epidermal thickness and biome-chanical properties of plantar tissues in diabetic foot显示文摘 | Chao CY Zheng YP Cheing GL | | 0，，： | 1 |
| 19 | Spatial and temporal distribution of the cloud optical depth over China based on MODIS satellite data during 2003–2016显示文摘The cloud optical depth(COD) is one of the important parameters used to characterize atmospheric clouds. We analyzed the seasonal variations in the COD over East Asia in 2011 using cloud mode data from the AERONET(Aerosol Robotic Network) ground-based observational network. The applicability of the MODIS(Moderate Resolution Imaging Spectroradiometer) COD product was verified and compared with the AERONET cloud mode dataset. There was a good correlation between the AERONET and the MODIS. The spatial and temporal distribution and trends in the COD over China were then analyzed using MODIS satellite data from 2003 to 2016. The seasonal changes in the AERONET data and the time sequence variation of the satellite data suggest that the seasonal variations in the COD are significant. The result shows that the COD first decreases and then increases with the season in northern China, and reaches the maximum in summer and minimum in winter.However, the spatial distribution change is just the opposite in southern China. The spatial variation trend shows the COD in China decreases first with time and gradually increases after 2014. And the trend of COD in the western and central China is consistent with that in China. While the trend of COD shows a continuously increasing over time in northeast China and the Pearl River Delta. | Xiaopan Li Huizheng Che Hong Wang Xiang'ao Xia Quanliang Chen Ke Gui Hujia Zhao Linchang An Yu Zheng Tianze Sun Zhizhong Sheng Chao Liu Xiaoye Zhang | 2019 | Journal of Environmental Sciences2019，31，6： | 1 |
| 20 | Observer-based event-triggered control for linear MASs under a directed graph and DoS attacks显示文摘In this paper,we investigate the observer-based event-triggered consensus problem for linear multi-agent systems(MASs)under a directed graph and denial-of-service(DoS)attacks.A type of DoS attacks launched by malicious attackers at irregular intervals is considered,which can cause communication channel disruption.A novel event-triggered secure control scheme based on a closed-loop observer is proposed to determine the scheduling of the controller update,and a separation method with less conservativeness is employed to design the controller and observer gains.Then,the frequency and duration of DoS attacks that can be tolerated are analysed for the observer-based secure consensus problem.In addition,a strictly positive minimal event-triggered time interval for each agent is designed with the help of the proposed eventtriggered condition to eliminate the Zeno behaviour.Finally,a numerical simulation is given to verify the theoretical analysis. | Shuo-Qiu Zhang Wei-Wei Che Chao Deng | 2022 | Journal of Control and Decision2022，9，3： | 1 |
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