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| 1 | The relation between HLA-DQA1 genes and genetic susceptibility to duodenal ulcer in Wuhan Hans显示文摘AIM To study the genetic susceptibility of HLA-DQA1 alleles to duodenal ulcer in Wuhan Hans.METHODS Seventy patients with duodenalulcer and fifty healthy controls were examinedfor HLA-DQA1 genotypes.HLA-DQA1 typing wascarried out by digesting the locus specificpolymerase chain reaction amplified productswith alleles specific restriction enzymes(PCR-RFLP),i.e.,Apal Ⅰ,Bsaj Ⅰ,Hph Ⅰ,Fok Ⅰ,Mbo Ⅱ and Mnl Ⅰ.RESULTS The allele frequencies of DQA1 * 0301and DQA1 * 0102 in patients with duodenal ulcerwere significantly higher and lower respectivelythan those in healthy controls(0.40 vs 0.20,P = 0.003,mcorret = 0.024)and(0.05 vs 0.14,P = 0.012,but Pcorret>0.05),respectively.CONCLUSION DQA1 * 0301 is a susceptiblegene for duodenal ulcer in Wuhan Hans,andthere are immunogenetic differences in HLA-DQA1 locus between duodenal ulcer patients andhealthy controls. | Du YP Deng CS Lu DY Huang MF Guo SF Hou W | 2000 | World Journal of Gastroenterology2000，6，1： | 37 |
| 2 | Leber's hereditary optic neuropathy is associated with the mitochondrial ND4 G11696A mutation in five Chinese families显示文摘 | Zhou XT Wei QP Yang L Tong Y Zhao FX Lu CJ Qian YP Sun YH Lu F Qu J Guan MX | 2006 | 中国生物学文摘2006，20，4： | 18 |
| 3 | Aminoglycoside-induced and non-syndromic hearing loss is associated with the G7444A mutation in the mitochondrial COI/tRNA (Ser(UCN)) genes in two Chinese families显示文摘 | Zhu Y Qian YP Tang XW Wang JD Yang L Liao ZS Li RH Ji JZ Li ZY Chen JF Choo DI Lu JX Guan MX | 2006 | 中国生物学文摘2006，20，4： | 16 |
| 4 | Novel redox potential-based screening strategy for rapid isolation of Klebsiella pneumoniae mutants with enhanced 1,3-propanediol- producing capability显示文摘 | Du, CY Zhang, YP Li, Y Cao, Z | 2007 | 中国生物学文摘2007，21，10： | 15 |
| 5 | 开放手术和经皮螺钉2种内固定方式联合外侧腰椎间融合术(LLIF)治疗成人退变性脊柱侧弯的效果比较显示文摘成人退变性脊柱侧弯(adultdegenerativescoliosis,ADS)老年人常见,50岁以上人群发病率约为6%。采用椎间融合术治疗ADS可获得有效椎间融合,同时纠正畸形。 | Attenello J Chang C Lee YP 陈恩良 吴增晖 | 2018 | 中国骨科临床与基础研究杂志2018，10，3： | 14 |
| 6 | Dietary factors and smoking as risk factors for PD in a rural population in China: a nested case-control study显示文摘 | Ma L Zhang L Gao XH Chen W Wu YP Wang Y Li XF Como P Kieburtz K Qiao YL | 2006 | 中国生物学文摘2006，20，8： | 13 |
| 7 | Symptom clusters and quality of life among patients with advanced heart failure显示文摘ObjectivesTo 与先进的心失败(HF ) 和与他们 .MethodsThis 是的生活(QoL ) 的质量的独立关系在病人之中识别症状簇会见了 119 个病人与的代表性的研究的第二等的数据分析在香港在一所地区性的医院的衰老老人单位推进了 HF。症状侧面和 QoL 被使用埃德蒙顿症状评价规模(ESAS ) 和 McGill QoL 问询表估计。探索因素分析被用来识别症状簇。层次回归分析被用来与他们的 QoL 检验独立关系,在调整病人们在先进年龄的年龄,性,和 comorbidities.ResultsThe 的效果以后(82.9 ±6.5 年) 。三不同症状簇被识别:他们是悲痛簇(呼吸,焦虑,和消沉的包括的短小) , decondition 簇(疲劳,睡意,恶心,和减少的胃口) ,和不快聚类(概括不快的疼痛,和感觉) 。这三症状簇说明了病人症状经验的 63.25% 变化。对在这些症状簇之间的中等关联小显示他们是独立人士互相。在调整年龄,性和 comorbidities 以后,悲痛(β=− 0.635, P <0.001 ) , decondition (β=− 0.148, P = 0.01 ) ,并且不快(β=− 0.258, P <0.001 ) 症状簇独立地预言他们的 QoL.ConclusionsThis 学习与先进 HF 在病人之中识别了特殊症状簇。结果使需要清楚些为为这限制生活的疾病优化症状控制开发辩解的照顾干预。 | Doris SF Yu Helen YL Chan Doris YP Leung Elsie Hui Janet WH Sit | 2016 | Journal of Geriatric Cardiology2016，13，5： | 12 |
| 8 | Transfusion transmitted virus infection in general populations and patients with various liver diseases in south China显示文摘INTRODUCTIONAlthough several specific detecting methods hadbeen applied to determine the hepatitis virus,therewas a lot of cryptogenic hepatitis without anyknown hepatitis infectious marker.Theprevalence of hepatitis G virus (HGV) (also knownas GB-C virus) infection has been reported to be 5%-13% in patients with non-A-E hepatitis andcirrhosis,however,there is little evidencesuggesting that HGV causes hepatitis in human. | Chen YP Liang WF Zhang L He HT Luo KX | 2000 | World Journal of Gastroenterology2000，6，5： | 7 |
| 9 | Quality of life and palliative care needs of elderly patients with advanced heart failure显示文摘 | Helen YL Chan Doris SF Yu Doris YP Leung Aileen WK Chan Elsie Hui | 2016 | Journal of Geriatric Cardiology2016，13，5： | 7 |
| 10 | 血清ALT水平影响非创伤性常规指数诊断乙型肝炎相关肝硬化的准确性显示文摘【据Joural of Viral Hepatitis 2020年8月报道】题:血清ALT水平影响非创伤性常规指数诊断乙型肝炎相关肝硬化的准确性(作者Chen YP等)研究表明,FIB-4及APRI等常规指数诊断慢性乙型肝炎肝硬化、显著肝纤维化在不同研究中存在差异。近期,研究者们也先后提出了多项新的常规指数,包括红细胞体积分布宽度-血小板比值(RPR)、谷氨酰转肽酶-血小板比值(GPR)及简易肝纤维化指数(eLIFT)。为评估ALT水平对这些常规指数诊断表现的影响,1005例慢性乙型肝炎患者被纳入回顾性分析,这些患者均已接受肝活检及常规血液检查。在该研究中,似然比10、0.1的对应值分别被确定为确认诊断、排除诊断界值。 | 林小钰 陈永鹏 CHEN YP HUANG LW LIN XY | 2020 | 临床肝胆病杂志2020，36，9： | 7 |
| 11 | Bioactive asterosaponins from the starfish Culcita novaeguineae显示文摘 | Tang HF Yi YH Li L Sun P Zhang SQ Zhao YP | 2005 | 第二军医大学学报2005，26，8： | 5 |
| 12 | Microbial community comparison of different biological processes for treating the same sewage显示文摘 | Liu, Xin-Chun Yang, Min Zhang, Yu Yang, Xiang-Ping Gan YP | 2007 | 中国生物学文摘2007，21，7： | 5 |
| 13 | Endogenous overproduction of beta-amyloid induces tau hyperphosphorylation and decreases the solubility of tau in N2a cells.显示文摘 | Wang YP Wang XC Tian Q Yang Y Zhang Q Zhang JY Zhallg YC Wang ZF Wang Q Li H Wang JZ | 2006 | 中国生物学文摘2006，20，9： | 5 |
| 14 | A New Isoflavone Glucoside from Astragalus membranaceus显示文摘A new isoflavone glucoside, 3’-methoxy-5’-hydroxy-isoflavone-7-O-β-D-glucoside, was isolated from the roots of Astragalus membranaceus and its structure waselucidated by spectroscopic data. | Cao, ZZ Cao, Y Yi, YJ Wu, YP Len, ZK Li, D Owen, NL | 1998 | Chinese Chemical Letters1998，9，6： | 4 |
| 15 | Structure of nano-copper and nano-conductive fibers显示文摘VARIOUS small inorganic solid grain catalysts, alloys and films consisting of various nano-size particles were prepared by chemical methods. The study of catalytic properties of nanostructured materials integrated material physics with chemistry, which promoted the development of materials science. | Zhang, ZK Cui, ZL Chen, KZ Wang, YN Ning, YP | 1997 | Chinese Science Bulletin1997，42，18： | 4 |
| 16 | Characteristics of alpha-synucleinopathy in centenarians显示文摘 | Ding ZT Wang Y Jiang YP Hashizume Y Yoshida M Mimuro M Inagaki T Iwase T | 2006 | 中国生物学文摘2006，20，8： | 4 |
| 17 | Mitochondrial cytochrome b sequences variation of Protura and molecular systematics of Apterygota显示文摘Mitochondrial cytochrome b genes of about 450 bp fragments from 3 proturan species, 5 collembolan species and 2 dipluran species have been sequenced. The number of nucleotide substitutions and Kimura 2-parameter distances have also been calculated, and a series of molecular phylogenetic trees reconstructed by using parsimony and distance methods. | Shao, HG Zhang, YP Xie, RD Yin, WY | 1999 | Chinese Science Bulletin1999，44，22： | 3 |
| 18 | 环境铅暴露与血压的关系:2003-2010美国健康和营养调查显示文摘在铅暴露逐渐降低的环境下,该文通过分析2003-2010美国健康和营养调查资料,旨在研究血铅与血压、高血压的关系。纳入研究对象12 725人,其中非洲裔21.1%,西语裔20.5%,白人58.4%,女性48.7%。与非非洲裔比较,非洲裔的血压[126.5/71.9比123.9/69.6mm Hg(1mm Hg=0. | Hara A Thijs L Asayama K Gu YM Jacobs L Zhang ZY Liu YP Nawrot TS Staessen JA 刘莉 叶鹏 | 2014 | 中华高血压杂志2014，22，10： | 3 |
| 19 | 美白牙膏去除牙齿外源性色斑的临床效果观察显示文摘目的 与仅含有 0 .32 1%氟化钠的牙膏相比 ,评价含有 0 .32 1%氟化钠及 2 0 %高清洁二氧化硅 (HCS)的牙膏减少外源性牙色斑的效果。方法 采用双盲、分层、二单位平行观察的临床研究方法。根据Lobene色斑指数均数 (色斑指数包括染色部位及染色程度 )、性别、将 15 8名年龄为 18~ 6 5岁的研究对象平衡地分为两组 ,随机地分配使用试验或对照牙膏。于基线、第 4周及第 8周固定由一名检查者完成研究对象的色斑指数测定。结果 4周时 ,使用美白牙膏的研究对象较对照组的牙齿色斑面积减少 17.4% ,染色程度减少 19.2 % (P <0 .0 1)。 8周时 ,使用美白牙膏的研究对象较对照组的牙齿色斑面积减少 38.6 % ,染色程度减少 39.6 % (P <0 .0 1)。结论 与对照组牙膏相比 ,使用含有 0 .32 1%氟化钠及 2 0 | 李雪 胡德渝 YP Zhang S Miller J Miller ME Petrone W Devizio AR Volpe | 2001 | 广东牙病防治2001，9，3： | 3 |
| 20 | Inheritance of resistance to race 7 of Cercospora sojina in soybeans and RAPD tagging of the resistance gene显示文摘Frog-eye leaf spot of soybean caused by Cercospora sojina Hara is a kind of worldwide disease. Resistance to race 7 of C. sojina was found to be due to a single dominant gene through analyzing resistant behavior of the cross NEAU91212 (susceptible to race 7)× NEAU9674 (resistant to all races). 3 RAPD markers linked to the resistant gene Rcsc 7 were identified using the BSA method. 2 fragments of OPS03620 and OPS03580 amplified with primer OPS03 co-dominantly segregated in the F2 individuals. The genetic distance between OPS03620 and the resistant gene is 8.7 cM. According to the co-dominant marker, the accuracy of predicting the homozygous and heterozygous resistant F2 individuals were 100% and 97.6%, respectively. | Zou, JJ Dong, W Yang, QK Cao, YP Chen, SY | 1999 | Chinese Science Bulletin1999，44，5： | 3 |
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