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110篇 您的检索式:作者名="Chan EM"
    题名 作者 年代 出处 被引量
1WRN解旋酶是治疗微卫星不稳定型癌症的新靶点显示文摘由基因突变或启动子超甲基化引发的DNA错配修复(MMR)缺陷会造成核苷酸重复区(微卫星)序列超突变,即微卫星不稳定性(MSI).MSI可促进多种癌症的发生,包括结肠(15%)、胃(22%)、子宫内膜(20%~30%)和卵巢(12%),其中有45%~60%不响应免疫检查点封锁.因此,MSI型肿瘤需要新的治疗方法.研究人员猜测由MSI导致的基因组缺陷能与其他基因的失活形成合成致死关系,协同杀死癌细胞.Chan EM Shibue T McFarland JM 2019国际老年医学杂志2019,40,6:3
2Lafora progressiveMyoclonus Epilepsy mutation database-EPM2A andNHLRC1(EPM2B)genes显示文摘Ianzano L Zhang J Chan EM 2005Hum Mutat2005,26,4:1
3The Arabidopsis CDPK-SnRK superfamily of protein kinases显示文摘Hrabak EM Chan CW Gribskov M 2003Plant Physiol2003,132,:1
4Apolipoprotein C-Ⅲ: understanding an emerging cardiovascular risk factor显示文摘Ooi EM Barrett PH Chan DC 2008Clin Sci (Lond)2008,114,:1
5Plasma apolipoprotein C-Ⅲ metabo- lism in patients with chronic kidney disease显示文摘Ooi EM Chan DT Watts GF 2011J Lipid Res2011,,:1
6Antineutrophil eytoplasmic autoantibodies : Diagnostically specific immune markers 显示文摘Tan EM Chan EKL Sullivan KF 1998Clin Exp Immunol1998,47,:1
7neurotrophin receptor P75NTR as a positive modulator of myelination显示文摘Cosgaya JM Chan JR Shooter EM 2002Science2002,298,5596:1
8Atorvastatin and fenofibrate have comparable effects on VLDL2apolipoprotein C-Ⅲ kinetics in men with the metabolic syndrome 显示文摘Chan DC Watts GF Ooi EM 2008Arterioscler Thromb Vasc Biol2008,28,:1
9Demystifying the management of hypertriglyceridaemia显示文摘Watts GF Ooi EM Chan DC 0,,:1
10Genetic mapping of a new Lafora progressive myoclonus epilepsy locus (EPM2B) on 6p22显示文摘Chan EM Bulman DE Paterson AD 2003J Med Genet2003,40,9:1
11Plasma apolipoprotein C-Ⅲmetabolism in patients with chronic kidney disease显示文摘Ooi EM Chan DT Watts GF 0,,:1
12Antinudear antibodies (ANAs):diagnostically specific immune markers and clues toward the understanding of systemic autoimmnity 显示文摘 Chan EK Sullivan KF Clin lmmunol Lmmunopathol 1 988 470,121,123:1
13Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells显示文摘Chan EM Ratanasirintrawoot S Park IH 0,,11:1
14Meniscus structure and function 显示文摘Wojtys EM Chan DB 2005Instr Course Lect2005,54,:1
15Association of apolipoprotein M with high-density lipoprotein kinetics in overweight-obese men显示文摘Ooi EM Watts GF Chan DC 2010Atherosclerosis2010,210,1:1
16Perfusion computed tomography:prediction of final infarct extent and stroke outcome显示文摘Parsons MW Pepper EM Chan V 2005Ann Neurol2005,58,5:1
17Spinal pseudoarthrosis complicating ankylosing spondylitis:comparison of CT and conventional tomog- raphy显示文摘Chan FL Ho EK Chau EM 1988AJR Am J Roentgenol1988,150,3:1
18The neurotrophin receptor p75NTR as a positive modulator of myelination 显示文摘Cosgaya JM Chan JR Shooter EM 2002Science2002,298,5596:1
19Plasma apolipoprotein CIII metab-olism in patients with chronic kidney disease显示文摘Ooi EM Chan DT Watts GF 2011J Lipid Res2011,52,4:1
20Guidelines for pr event ion of NSAID2relat ed ulcer complicat ions显示文摘Lanza FL Chan FK Quigley EM 2009Am J Gastroenterol2009,104,3:1
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