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| 1 | 在糖尿病的 nephropathy 吸烟: 在燃料坦克的火花吗?显示文摘 Diabetic nephropathy is associated with high morbidity and mortality and the prevalence of this disease is continuously increasing worldwide.Long-term diabetes increases the likelihood of developing secondary complications like nephropathy,the most common cause of end stage renal disease.Usually,other factors like hypertension,alcoholism and smoking also partly contribute to the progression of diabetic nephropathy.Among this,cigarette smoking in diabetes has been repeatedly confirmed as an independent risk factor for the onset and progression of diabetic nephropathy.Various studies suggest that smoking is a major fuel in the development of high oxidative stress and subsequently hyperlipidemia,accumulation of advanced glycation end products,activation of the renin angiotensin system and Rho-kinase,which are observed to play a pathogenic role in the progression of diabetic nephropathy.Furthermore,cigarette smoking in diabetic patients with vascular complications produces a variety of pathological changes in the kidney,such as thickening of the glomerular basement membrane and mesangial expansion with progression in glomerulosclerosis and interstitial fibrosis,which ultimately results in end stage renal failure.Strong associations are consistently found between chronic cigarette smoking and diabetic microvascular complications.A diverse group of studies unveil potentialmechanisms that may explain the role of cigarette smoking in the progression of diabetic nephropathy.Tremendous efforts are being made to control smoking mediated progression of diabetic nephropathy,but no promising therapy is yet available.The present review critically discusses the possible detrimental role of chronic cigarette smoking in the progression of diabetic nephropathy and various possible pharmacological interventions to attenuate the exacerbation of diabetic nephropathy. | Vishal Arvind Chakkarwar | 2012 | World Journal of Diabetes2012，3，12： | 4 |
| 2 | Ameliorative effect of combination of benfotiamine and fenofibrate in diabetes-induced vascular endothelial dysfunction and nephropathy in the rat显示文摘 | Pitchai Balakumar Vishal Arvind Chakkarwar Manjeet Singh | 2009 | Molecular and Cellular Biochemistry (-)2009，，1： | 3 |
| 3 | Vascular endothelial dysfunction: a tug of war in diabetic nephropa- thy? 显示文摘 | Balakumar P Chakkarwar VA Krishan P | 2009 | Biomed Pharmacother2009，63，： | 1 |
| 4 | Ameliorative effect of combina-tion of benfotiamine and fenofibrate in diabetes-induced vascular endo-thelial dysfunction and nephropathy in the rat显示文摘 | Balakumar P Chakkarwar VA Singh M | | 0，，1： | 1 |
| 5 | Vascular endothelial dysfunction:a tug of war in diabetic nephropathy显示文摘 | Balakumar P Chakkarwar V A Krishan P | 2009 | Biomedicine&Pharmacotherapy2009，63，3： | 1 |
| 6 | Experimental models for nephropathy 显示文摘 | Balakumar P Chakkarwar V A Kumar V | 2008 | J Renin Angiotensin Aldosterone Syst2008，9，4： | 1 |
| 7 | Amelinrative effct of com- bination of benfotiamine and fenofibrate in diabetes -induced vas- cular endothelial dysfunction and nephropathy in the rat 显示文摘 | Balakumar P Chakkarwar VA Singh M | 2009 | Mol Cell Biochem2009，320，： | 1 |
| 8 | Fenofibrate attenuates nicotine-induced vascular endothelial dysfunction in the rat 显示文摘 | Chakkarwar VA | 2011 | Vascular Pharmacol2011，55，56： | 1 |
| 9 | Image Stitching Using Harris Feature Detection and Random Sampling显示文摘 | Chandratre R Chakkarwar V | 2014 | International Journal of Computer Applications2014，89，05： | 1 |
| 10 | Insulin glargine:a lung acting insulin analog显示文摘 | Chakkarwar PN Manjrekar NA | 2005 | J Postgrad Med2005，51，1： | 1 |
| 11 | Ameliorative effect of combination of benfotiamine and fenofibrate in diabetes- induced vascular endothelial dysfunction and nephropathy in the rat 显示文摘 | Balakumar P Chakkarwar VA Singh M | 2009 | Mol Cell Biochem2009，320，12： | 1 |
| 12 | Experimental models for nephropathy 显示文摘 | Balakumar P Chakkarwar VA Kumar V | 2008 | J Renin Angiotensin Aldosterone Syst2008，9，4： | 1 |
| 13 | An observational non-interventional study of people with diabetes beginning or changed to insulin analogue therapy in non-Western countries: The A 1 chieve study显示文摘 | Philip Home Nabil El Naggar Mohammed Khamseh Guillermo Gonzalez-Galvez Chunduo Shen Praful Chakkarwar Yang Wenying | 2011 | Diabetes Research and Clinical Practice2011，，3： | 1 |
| 14 | Ameliorative effect of combination of benfotiamine and fenofibrate in diabetes-induced vascular endothelial dysfunction and nephropathy in the rat显示文摘 | Balakumar P Chakkarwar VA Singh M | | 0，，： | 1 |
| 15 | Insulin glargine:a long acting insulin analog 显示文摘 | Chakkarwar P N Manjrekar N A | 2005 | J Postgrad Med2005，51，1： | 1 |
| 16 | Ameliorative effect ofcombination of benfotiamine and fenofibrate in diabetes-induced vascular endothelial dysfunction and nephropathy in the rat 显示文摘 | Balakumar P Chakkarwar VA Singh M | 2009 | Mol Cell Biochem2009，320，： | 1 |
| 17 | Ameliorative effect of combinaiion of beltfotiamine and fenofibrate in diabetes-induced vascularendothelial dysfunction and nephropathy in the rat 显示文摘 | Balakumar P Chakkarwar VA Singh M | 2009 | Mol Cell Biochem2009，320，12： | 1 |
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