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| 1 | A deep learning-enabled portable imaging flow cytometer for cost-effective, highthroughput, and label-free analysis of natural water samples显示文摘We report a deep learning-enabled field-portable and cost-effective imaging flow cytometer that automatically captures phase-contrast color images of the contents of a continuously flowing water sample at a throughput of 100 mL/h.The device is based on partially coherent lens-free holographic microscopy and acquires the diffraction patterns of flowing micro-objects inside a microfluidic channel.These holographic diffraction patterns are reconstructed in real time using a deep learning-based phase-recovery and image-reconstruction method to produce a color image of each micro-object without the use of external labeling.Motion blur is eliminated by simultaneously illuminating the sample with red,green,and blue light-emitting diodes that are pulsed.Operated by a laptop computer,this portable device measures 15.5 cm×15 cm×12.5 cm,weighs 1 kg,and compared to standard imaging flow cytometers,it provides extreme reductions of cost,size and weight while also providing a high volumetric throughput over a large object size range.We demonstrated the capabilities of this device by measuring ocean samples at the Los Angeles coastline and obtaining images of its micro-and nanoplankton composition.Furthermore,we measured the concentration of a potentially toxic alga(Pseudo-nitzschia)in six public beaches in Los Angeles and achieved good agreement with measurements conducted by the California Department of Public Health.The cost-effectiveness,compactness,and simplicity of this computational platform might lead to the creation of a network of imaging flow cytometers for largescale and continuous monitoring of the ocean microbiome,including its plankton composition. | Zoltán Gӧrӧcs Miu Tamamitsu Vittorio Bianco Patrick Wolf Shounak Roy Koyoshi Shindo Kyrollos Yanny Yichen Wu Hatice Ceylan Koydemir Yair Rivenson Aydogan Ozcan | 2018 | Light(Science & Applications)2018，7，1： | 14 |
| 2 | The value of diffusion- weighted MRI in the diagnosis of malignant and benign urinary bladderlesions显示文摘 | Avcu S Koseoglu M N Ceylan K | 2011 | Br J Radiol2011，84，： | 1 |
| 3 | Activated protein C and normal saline infusion might prevent deleterious effects of remote acute lung injury caused by intestinal ischemia- reperfusion: an experimental study in the rat model显示文摘 | Tarhan OR Ceylan BG Kapucuoglu N | 2011 | J Surg Res2011，168，1： | 1 |
| 4 | High available phosphorus corn and phytase in layer diets 显示文摘 | Ceylan N | 2003 | Poultry Science2003，82，5： | 1 |
| 5 | Assessment of left ventricular functions with tissue Doppler,strain and strain rate echocardiography in children with juvenile idiopathic arthritis:An observational study显示文摘 | Yilmaz O Ceylan O Orün UA | | 0，，04： | 1 |
| 6 | Apossible etiology of the internal derangement of thetemporomandibular joint based on the MRI observa-tions of the lateral pteiygoid muscle显示文摘 | Taskaya-Yilmaz N Ceylan G Incesu L | 2005 | Surg RadiolAnat2005，27，1： | 1 |
| 7 | Successful treatment of mul- tidrug-resistant Acinetobacter baumannii ventriculitis with intravenous and intraventricular colistin显示文摘 | Dalqic N Ceylan Y Sancar M | 2009 | Ann Trop Paediatr2009，29，2： | 1 |
| 8 | The importance of administration of early surfactant and nasal continuous positive airway pressure in newborns with respiratory distress syndrome 显示文摘 | Ceylan A Gezer S Demir N | 2014 | Turk Pediatri Ars2014，49，3： | 1 |
| 9 | Menopausal symptoms and quality of life in Turkish women in the climacteric period显示文摘 | Ceylan B Ozerdogan N | 2014 | Climacteric2014，17，： | 1 |
| 10 | Arsenic related hearing loss in miners显示文摘 | Gülin G?k?en Kesici ?lhan ünlü Arzu Ba?türk Top?u Ceylan Demir Bal Engin Tutkun ?mer H?n? Y?lmaz | 2016 | American Journal of Otolaryngology--Head and Neck2016，，1： | 1 |
| 11 | Retrospective, Demographic, and Clinical Investigation of the Causes of Postoperative Infection in Patients With Lumbar Spinal Stenosis Who Underwent Posterior Stabilization显示文摘 | Yaldiz C Yaldiz M Ceylan N | 2015 | Medicine (Baltimore)2015，94，29： | 1 |
| 12 | Successful treatment ofmuitidrug-resistant Acinetobacter baumanii ventriculitis with in-travenous and intraventricular colistin显示文摘 | Dalgic N Ceylan Y Sancar M | 2009 | Ann Trop Paediatr2009，29，2： | 1 |
| 13 | Effect of Be content on some characteris- tics of Cu-AI-Be shape memory alloys 显示文摘 | Balo S N Ceylan M | 2002 | Journal of Materials Processing Technology2002，124，： | 1 |
| 14 | Rural women and agrotourism in the context of sustainable rural development: a case study from Turkey显示文摘 | Akpinar N Talay I Ceylan C | 2004 | Kluwer Journal2004，，6： | 1 |
| 15 | Successful treatment of multidrug-resistant Acinetobacter baumannii ventriculitis with intravenous and intraventricular colistin显示文摘 | Dalgic N Ceylan Y Sancar M | 2009 | Annals of Tropical Paediatrics2009，29，： | 1 |
| 16 | Extracion of pins from the aiway with flexible bronchoscopy显示文摘 | Gencer M Ceylan E Koksal N | | 0，，06： | 1 |
| 17 | Rural women and agritourism in the context of sustainable rural development : a case study from Turkey 显示文摘 | AKPINAR N TALAY I CEYLAN C | 2004 | Kluwer journal2004，，6： | 1 |
| 18 | Rural women and agro tourism in the context of sustainable rural development: a ease study from Turkey显示文摘 | Akpinar N Talay N Ceylan C | 2004 | Environment Development and Sustainability2004，6，4： | 1 |
| 19 | Erectile dysfunction prevalence and sexual function status in patient with chronic ob- structive pulmonary disease显示文摘 | Koseoglu N Koseoglu H Ceylan E | 2005 | J Urol2005，174，： | 1 |
| 20 | Pulmonary and vascular manifestations of Behcet disease imaging findings显示文摘 | Ceylan N Bayraktaroglu S Erturk S M | 2010 | AJR2010，194，2： | 1 |
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