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| 1 | Therapeutic effect of caffeic acid phenethyl ester on cerulein-induced acute pancreatitis显示文摘AIM: To evaluate the therapeutic role of caffeic acid phenethyl ester (CAPE) in a rat model of ceruleaninduced acute pancreatitis (AP).METHODS: Seventy male Wistar albino rats were divided into seven groups. Acute edematous pancreatitis was induced by subcutaneous cerulein injection (20 μg/kg) four times at 1-h intervals. CAPE (30 mg/kg) was given by subcutaneous injection at the beginning (CAPE 1 group) and 12 h after the last cerulein injection (CAPE 2 group). Serum amylase, lipase, white blood cell count, and tumor necrosis factor (TNF)-α levels were measured, and pancreatic histopathology was assessed. RESULTS: In the AP group, amylase and lipase levels were found to be elevated and the histopathological evaluation showed massive edema and inflammation of the pancreas, with less fatty necrosis when compared with sham and control groups. Amylase and lipase levels and edema formation decreased signif icantly in the CAPE therapy groups (P < 0001); especially in the CAPE 2 group, edema was improved nearly completely (P = 0001). Inflammation and fatty necrosis were partially recovered by CAPE treatment. The pathologicalresults and amylase level in the placebo groups were similar to those in the AP group. White blood cell count and TNF-α concentration was nearly the same in the CAPE and placebo groups.CONCLUSION: CAPE may be useful agent in treatment of AP but more experimental and clinical studies are needed to support our observation of benef icial effects of CAPE before clinical usage of this agent. | Mehmet Buyukberber M Cemil Savas Cahit Bagci Mehmet Koruk Murat T Gulsen Ediz Tutar Tugba Bilgic Nurdan Ceylan | 2009 | World Journal of Gastroenterology2009，15，41： | 4 |
| 2 | Comparison of tenofovir and entecavir in patients with chronic HBV infection 显示文摘 | Ceylan B Yardimci C Fincanci M | 2013 | Eur Rev Med Pharmacol Sei2013，17，18： | 1 |
| 3 | Investigation of the casting microstructure of a Fe-base, Cr Ni Mo du- plex alloy显示文摘 | Ceylan M Kuzucu V Aksoy M | 1997 | Journal of Materials Processing Technolo- gy1997，69，： | 1 |
| 4 | Adsorption of boron from aqueous solutions by activated carbon impregnated with salicylic acid: Equilibrium, kinetic and thermodynamic studies显示文摘 | CAN BZ CEYLAN Z KOCAKERIM M M | 2012 | Desalination and Water Treatment2012，40，123： | 1 |
| 5 | Evaluation of Co listin-Ampicillin/Sulbactam Combination Efficacy in Imi penem-Resistant Acinetobacter baumann{i Strains 显示文摘 | Cikman A Ceylan MR Parlak M | 2013 | Mikrobiyol Bul2013，47，1： | 1 |
| 6 | Estimation of Flexural Capacity of Quadrilateral FRP-Confined RC Columns Using Combined Artificial Neural Network 显示文摘 | Koroglu M A Ceylan M Arslan M H | 2012 | Engineering Structures2012，42，： | 1 |
| 7 | The value of diffusion- weighted MRI in the diagnosis of malignant and benign urinary bladderlesions显示文摘 | Avcu S Koseoglu M N Ceylan K | 2011 | Br J Radiol2011，84，： | 1 |
| 8 | The con- stituents of essential oil and in vitro antimicrobial activity of Micromeria cilicica from Turkey 显示文摘 | DURU M E OZTURK MU A CEYLAN O | 2004 | J Ethnopharmacol2004，94，1： | 1 |
| 9 | Hybridizing the harmony search algorithm with a spreadsheet 4 solver ’ for solving continuous engineering optimization problems 显示文摘 | Ayvaz M T Kayhan A H Ceylan H | 2009 | Engineering Optimization2009，41，12： | 1 |
| 10 | Single step synthesis of nanocrystalline ZnO via wet-milling 显示文摘 | OZCAN S CAN M M CEYLAN A | 2010 | Materials Letters2010，64，22： | 1 |
| 11 | The expression of MMP-2, MMP-7, MMP 9, and TIMP- 1 in chronic rhinosinusitis and nasal polyposis显示文摘 | CAN I H CEYLAN K CAYDERE M | 2008 | Otolaryngol Head Neck Surg2008，139，： | 1 |
| 12 | Coagulopathy in multiple traumas 显示文摘 | Turtay M G Kirimlioglu V Ceylan C | 2010 | Ulus Travma Aeil Cerrahi Derg2010，16，3： | 1 |
| 13 | Successful treatment of mul- tidrug-resistant Acinetobacter baumannii ventriculitis with intravenous and intraventricular colistin显示文摘 | Dalqic N Ceylan Y Sancar M | 2009 | Ann Trop Paediatr2009，29，2： | 1 |
| 14 | A hybrid intrusion detection system design for computer network security 显示文摘 | Ali Aydin M Halim Zaim A Gokhan Ceylan K | 2009 | Computers & Electrical Engineering2009，35，18： | 1 |
| 15 | Retrospective, Demographic, and Clinical Investigation of the Causes of Postoperative Infection in Patients With Lumbar Spinal Stenosis Who Underwent Posterior Stabilization显示文摘 | Yaldiz C Yaldiz M Ceylan N | 2015 | Medicine (Baltimore)2015，94，29： | 1 |
| 16 | Adiponeetin as a biomarker of systemic inflammatory response in smoker patients with stable and exacerbation phases of chronic obstructive pulmonary disease 显示文摘 | Krdar S Serter M Ceylan E | 2009 | Scand J Clin Lab Invest2009，69，2： | 1 |
| 17 | Adiponectin as a biomarker of systemic inflammatory response in smoker patients with stable and exacerbation phases of chronic ob- structive pulmonary disease 显示文摘 | Kirdar S Serter M Ceylan E | 2009 | Scand J Clin Lab Invest2009，69，2： | 1 |
| 18 | The evaluation of myocardial function of patients in the early stage of acute ischemic stroke by two-dimensional speckle tracking echocardiography显示文摘 | Ermis E Demirelli S Ceylan M | 2016 | J Clin Ultrasound2016，44，5： | 1 |
| 19 | Successful treatment ofmuitidrug-resistant Acinetobacter baumanii ventriculitis with in-travenous and intraventricular colistin显示文摘 | Dalgic N Ceylan Y Sancar M | 2009 | Ann Trop Paediatr2009，29，2： | 1 |
| 20 | Effect of Be content on some characteris- tics of Cu-AI-Be shape memory alloys 显示文摘 | Balo S N Ceylan M | 2002 | Journal of Materials Processing Technology2002，124，： | 1 |
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