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| 1 | Mammary gland growth and vascularity at parturition and during lactation in primiparous ewes fed differing levels of selenium and nutritional plane during gestation显示文摘Background: Objectives were to examine the effects of selenium(Se) supply and maternal nutritional plane during gestation on mammary gland growth, cellular proliferation, and vascularity at parturition and d 20 of lactation. Rambouillet primiparous ewes(n = 84) were allocated to treatments in a 2 x 3 factorial. Factors were dietary Se(adequate Se [ASe, 11.5 μg/kg BW] or high Se [HSe, 77.0 μg/kg BW]) and nutritional plane(60% [RES], 100% [CON], or 140% [EXC]). At parturition, lambs were removed and 42 ewes(7/treatment) were necropsied. Remaining ewes were fed a common diet meeting requirements for lactation and mechanically milked twice daily until necropsy on d 20. At both necropsy periods, mammary glands were dissected and tissues harvested. Samples were analyzed for RNA, DNA, and protein content, cell proliferation, and vascularity. Where interactions were present(P ≤ 0.05), least squares means from the highest-order interaction are presented. Results: Final body weight of ewes was least(P ≤ 0.002) in RES, intermediate for CON, and greatest for EXC, regardless of stage of the ewe at necropsy(parturition or d 20 of lactation). In ewes necropsied at parturition, mammary glands were heavier(P = 0.02) in EXC compared to RES, with CON intermediate. Concentration of RNA(mg/g) was decreased(P = 0.01) in EXC compared to CON at parturition. There was a tendency(P = 0.07) for a Se by nutrition interaction in percentage of cells proliferating where ASe-EXC ewes had greater(P ≤ 0.02) number of proliferating cells then all other treatments. Mammary vascular area tended(P = 0.08) to be affected by a Se by nutrition interaction where ASe-CON had less(P = 0.007) vascular area than HSe-CON ewes. In ewes necropsied at d 20 of lactation, the number of alveoli per area was decreased(P ≤ 0.05) in RES compared to CON and EXC-fed ewes. Conclusions: Results of this study indicate that proper maternal nutritional plane during gestation is important for mammary gland development, even out to d 20 of lactation. | Tammi L Neville Allison M Meyer Arshi Reyaz Pawel B Borowicz Dale A Redmer Lawrence P Reynolds Joel S Caton Kimberly A Vonnahme | 2013 | Journal of Animal Science and Biotechnology2013，4，4： | 3 |
| 2 | The antigenic structure of the influenza virus A/PR/8/34 hemagglutinin (H1 subtype)显示文摘 | Caton AJ Brownlee GG Yewde11 JW | 1982 | Ce111982，31，21： | 1 |
| 3 | The search for authenticity in the pilgrim experience 显示文摘 | BelhassenY ? Caton K and Stewart K C | 2008 | Annals of Tourism Re-search2008，35，3： | 1 |
| 4 | Risk factors for isolated biliary atresia, National Birth Defects Prevention Study, 1997-2002显示文摘 | THE N S HONEIN M A CATON A R | 2007 | Am J Med Genet A2007，143，19： | 1 |
| 5 | Wind measurement by Doppler radar显示文摘 | Caton P A F | 1963 | Metet / or Mag1963，92，： | 1 |
| 6 | An investigation of a cause of backfire and its control due to crevice volumes in hydro- gen fueled engine显示文摘 | Lee J T Caton J A Lee C W | 2001 | Journal of Engineering for Gas Tur bines and Power2001，123，1： | 1 |
| 7 | Influence of energy supplementation on grazing ruminants:requirements and responses显示文摘 | CATON J S DHUYVETTER D V | 1997 | Journal of Animal Science1997，75，2： | 1 |
| 8 | Notch2 receptor signal- ing controls functional differentiation of dendritic cells in the spleen and intestine 显示文摘 | Lewis KL Caton ML Bogunovic M | 2011 | Immunity2011，35，5： | 1 |
| 9 | The antigenici- ty and evolution of influenza H1 haemagglutinin, from 1950-1957 and 1977-1983: two pathways from one gene 显示文摘 | Raymond F L Caton A J Cox N J | 1986 | Virology1986，148，2： | 1 |
| 10 | Influence of undegraded intake protein on intake,digestion,serum hormones and metabolites,and nitrogen balance in sheep显示文摘 | Swanson K C Caton J S Redmer D A | 2000 | Small Rumin Res2000，35，： | 1 |
| 11 | Tibial autogenous cancel ous bone as an alternative donor site in maxil ofacial surgery:a preliminary report显示文摘 | Catone GA Reimer BL McNeir D | | 0，，12： | 1 |
| 12 | Role of hyperglycemia in nitrotyrosine postprandial generation显示文摘 | Jones SC Saunders HJ Catone B | | 0，，： | 1 |
| 13 | Statistical analysis of the vehicle pollutant emissions derived from several European road tunnel studies 显示文摘 | COLBERG A Christina TONA Bruno CATONE Giovanni | 2005 | Atmospheric Environment2005，39，13： | 1 |
| 14 | On the destruction of availability (exergy) due to combustion processes: With specific application to internal-combustion engines显示文摘 | Caton Jerald A | 2000 | Energy2000，25，11： | 1 |
| 15 | Management of impacted teeth显示文摘 | Ailing C C Catone G A | 1993 | J Oral Maxillofac Surg1993，51，11： | 1 |
| 16 | Nicotinamide mononueleotide protects against pro- inflammatory cytokine-mediated impairment of mouse islet function 显示文摘 | CATON P W KIESWICH J YAQOOB M M | 2011 | Diabetologia2011，54，12： | 1 |
| 17 | Uteroplacental vascular development and pla-centalfunction:an update显示文摘 | Reynolds LP Borowicz PP Caton JS | 2010 | Int J Dev Biol2010，54，23： | 1 |
| 18 | The antigenic structure of the influenza virus A/PR/8 /34hemagglutinin (H1 subtype) 显示文摘 | CATON A J BROWNLEE G G YEWDELL J W | 1982 | Cell1982，31，21： | 1 |
| 19 | Complications of llizarov leg lengthening: a comparative study between patients with leg length dis- crepancy and short stature显示文摘 | Vargas Barreto B Caton J Merabet Z | 2007 | Int Orthop2007，31，： | 1 |
| 20 | CD4 * CD25 + regulatory T ceils in autoimmune arthritis显示文摘 | Oh S Rankin AL Caton AJ | 2010 | Immunol Rev2010，233，1： | 1 |
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