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| 1 | 南菲律宾地区类埃达克岩和富铌玄武质熔岩的成因<英文>显示文摘埃达克岩(adakite)最初是指由消减板片玄武岩物质熔融形成的富硅、富钠、高Sr/Y和La/Yb比值的弧火山熔岩。它通常产在会聚带,这个部位的年轻的、因而仍然是热的大洋板片正在发生俯冲消减。富铌的岛弧玄武岩则是中等到高碱的镁铁质熔岩,它们相对于正常的岛弧玄武岩含有较多的高场强元素(HFSE)。这些玄武岩通常与埃达克岩共生,而这一组合一直被用于论证他们的高HFSE含量是因为他们的地幔源区受到板片来源的熔体的交代。先前的区域研究表明,南菲律宾是埃达克岩和富铌岛弧玄武岩的一个典型产地。然而最近的详细研究显示,尽管该地区的一些岛弧火山岩是类埃达克岩的,但是它们很可能是来自地幔楔的母岩浆的分异作用的产物,而这里的地幔楔主要是受沉积来源的成分交代的,此外,菲律宾南部最典型的富铌熔岩中HFSE的富集,也很有可能是起因于似乎是西太平洋边缘特有的富集地幔组分的熔融。这些结果提出了如下问题:南菲律宾是否存在真正的板片来源的熔体?这里的富铌岛弧熔岩是否起因于地幔楔被这种熔体交代? | Paterno R CASTILLO | 2002 | 岩石学报2002，18，2： | 72 |
| 2 | The wonders of BMP9:From mesenchymal stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism to regenerative medicine显示文摘Although bone morphogenetic proteins(BMPs)initially showed effective induction of ectopic bone growth in muscle,it has since been determined that these proteins,as members of the TGF-b superfamily,play a diverse and critical array of biological roles.These roles include regulating skeletal and bone formation,angiogenesis,and development and homeostasis of multiple organ systems.Disruptions of the members of the TGF-b/BMP superfamily result in severe skeletal and extra-skeletal irregularities,suggesting high therapeutic potential from understanding this family of BMP proteins.Although it was once one of the least characterized BMPs,BMP9 has revealed itself to have the highest osteogenic potential across numerous experiments both in vitro and in vivo,with recent studies suggesting that the exceptional potency of BMP9 may result from unique signaling pathways that differentiate it from other BMPs.The effectiveness of BMP9 in inducing bone formation was recently revealed in promising experiments that demonstrated efficacy in the repair of critical sized cranial defects as well as compatibility with bone-inducing bio-implants,revealing the great translational promise of BMP9.Furthermore,emerging evidence indicates that,besides its osteogenic activity,BMP9 exerts a broad range of biological functions,including stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism.This review aims to summarize our current understanding of BMP9 across biology and the body. | Sami Mostafa Mikhail Pakvasa Elam Coalson Allen Zhu Alex Alverdy Hector Castillo Jiaming Fan Alex Li Yixiao Feng Di Wu Elliott Bishop Scott Du Mia Spezia Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Sherwin S·Ho Aravind Athiviraham Michael J·Lee Jennifer Moriatis Wolf Guillermo A·Ameer Hue H·Luu Rex C·Haydon Jason Strelzow Kelly Hynes Tong-Chuan He Russell R·Reid | 2019 | Genes & Diseases2019，6，3： | 15 |
| 3 | HIMU和FOZO型OIB源区形成新模型:沉积碳酸盐再循环显示文摘大多数OIB源区都含有经俯冲作用或其他过程再循环进入地幔的地壳组分。早期研究一般认为再循环地壳组分为MORB,经过海底热液蚀变及俯冲作用后具有高U/Pb值,最终进入OIB源区形成具极端放射性成因Pb同位素组成特征(^206Pb/^204Pb〉20)的HIMU型OIB。但是用俯冲MORB型洋壳来解释HIMU的地球化学特征受到了越来越多的质疑。 | Paterno R Castillo 刘勇胜 | 2015 | 矿物岩石地球化学通报2015，34，4： | 10 |
| 4 | 高精度铅同位素^207Pb-^204Pb双稀释剂TIMS测试方法显示文摘利用热电离质谱(TIMS)和207Pb-204Pb双稀释法测定低含量Pb岩石样品的同位素比值,可以有效校正由质谱分析造成的同位素分馏效应,提高铅同位素比值测定的精度和准确度。本文利用中国科学院广州地球化学研究所Triton TIMS,建立了207Pb-204Pb双稀释剂测试方法,并对Pb含量为5~20 ng的国际标样SRM981进行3个月的TIMS仪器测定,双稀释剂法外部校正后得到的206Pb/204Pb、207Pb/204Pb和208Pb/204Pb外部精度分别为±0.0034、±0.0046和±0.0100(2sd,n=28)。达到或优于其他国际高水平TIMS实验室双稀释剂法测定精度。同时,运用新方法对国际岩石标样AGV-2和BCR-2进行测定,得到的比值分别为:206Pb/204Pb=18.870±0.006、207Pb/204Pb=15.619±0.003、208Pb/204Pb=38.546±0.012和206Pb/204Pb=18.752±0.011、207Pb/204Pb=15.619±0.005、208Pb/204Pb=38.723±0.020,与国际同类实验室测定结果和精度一致,表明该新建方法是可靠的。运用207Pb-204Pb双稀释剂法对岩石样品进行测定,可获得高精度铅同位素比值,尤其对低含量Pb的基性、超基性地质样品测定有很大的优势。 | 刘希军 王桂琴 CASTILLO P R 许继峰 黄丰 余红霞 陈玲 | 2013 | 地球化学2013，42，2： | 6 |
| 5 | Role of cytochrome P-450 2E1 in ethanol-, carbon tetrachloride- and iron-dependent microsomal lipid peroxidation显示文摘 | Castillo T Koop D R Kamimura S | 1992 | Hepatology1992，16，4： | 2 |
| 6 | Lymphoepithelial cysts and cystic lymphangiomas: Underrecognized benign cystic lesions of the pancreas显示文摘AIM: To identify their diagnostic and prognostic clinical characteristics in a large series.METHODS: Retrospective review of clinicopathologic and imaging characteristics of patients diagnosed with lymphoepithelial cysts and cystic lymphangiomas of the pancreas at Massachusetts General Hospital.RESULTS: Twelve patients were identified between 1/1/1997 and 8/1/2007. Their median age was 55.5 years(range 19-78 years), and 6 were females. The le-sion was incidentally discovered in half of the patients.Contrast enhanced computed tomography demonstrat-ed that the cysts had thin walls, without calcifications, pancreatic duct dilation or pancreatic parenchyma inva-sion. Endoscopic ultrasound with fine needle aspiration(EUS/FNA) confirmed the diagnosis of a lymphoepithe-lial cyst in 3 patients, one of whom was spared an op-eration and continues to do well after 6 years. Eleven patients had a resection: 3 pancreaticoduodenecto-mies, 7 distal pancreatectomies, and 1 enucleation. The median size of the cysts was 3 cm(range 2-20 cm). At a median follow-up of 57 mo no recurrences or other pancreas-related conditions occurred.CONCLUSION: Lymphoepithelial cysts and cystic lymphangiomas of the pancreas can be diagnosed with a combination of contrast-enhanced computed tomog-raphy scans and EUS/FNA. If the lesion is asymptom-atic, an operation might be avoided. | Ioannis T Konstantinidis Avinash Kambadakone Onofrio A Catalano Dushyant V Sahani Vikram Deshpe David G Forcione Jennifer A Wargo Carlos Fernandez-del Castillo Keith D Lillemoe Andrew L Warshaw Cristina R Ferrone | 2014 | World Journal of Gastrointestinal Surgery2014，6，7： | 2 |
| 7 | The effect of protein supplementa-tion on nitrogen utilization in lactating dairy cows fed grass si-lage diets显示文摘 | Castillo A R Kebreab E | 2001 | J Anim Sci2001，79，： | 1 |
| 8 | Recommendations on use of direct oral anticoagulants in the perioperative period显示文摘 | Llau JV Ferrandis R Castillo J | 2012 | Med Clin (Barc)2012，1392，： | 1 |
| 9 | Phase H study of neoadjuvant weekly nab-paelitaxel and carboplatin, with bevaci- zumab and trastuzumab, as treatment for women with locally ad- vanced HER2 + breast cancer显示文摘 | Yardley DA Raefsky E Castillo R | 2011 | Clin Breast Cancer2011，11，5： | 1 |
| 10 | Poultry slaughter wastewater treatment with an up-flow anaerobic sludge blanket(UASB)reactor显示文摘 | CHAVEZ P C CASTILLO L R DENDOOVEN L | 2005 | Bioresource Technology2005，96，： | 1 |
| 11 | A blast of gas in the latest Paleocene: simulation first-order effects of massive dissociation of oceanic methane hydrate显示文摘 | Castillo M M Walker J G C | 1997 | Geology1997，25，： | 1 |
| 12 | Structural, optical and electrical characterization of In/CdS/glass thermally annealed system 显示文摘 | Mendoza-Galvan A Ramirez-Bon R | 2000 | Thin Solid Films2000，373，： | 1 |
| 13 | Interactive effects of ozone and drought stress on pigments and activities of antioxidantive enzymes in Pinus halepensis 显示文摘 | Alonso R Elvira S Castillo F J | 2001 | Plant Cell Environ2001，24，： | 1 |
| 14 | Solid-phase microcxtraction as a methodology in the identification of irradiated ground beef显示文摘 | Caja M M Castillo M L R Blanch G P | 2008 | Food Chemistry2008，110，2： | 1 |
| 15 | MLVA geno- typing of human Brucella isolates from Peru显示文摘 | Stairs H L Espinosa B Castillo R | 2009 | Trans R Soc Trop Med Hyg2009，103，4： | 1 |
| 16 | Oral vinorelbine for the treatment of metastatic Non-small Cell Lung Cancer in elderly patients:a phase II trial of efficacy and toxicity显示文摘 | Kanard A Jatoi A Castillo R | 2004 | Lung Cancer2004，43，3： | 1 |
| 17 | Neurological deterioration in acute lacunar infarctions:The role of excitatory and inhibyory neurotransmitters显示文摘 | Serend J Leira R Castillo J | 2001 | Stroke2001，32，： | 1 |
| 18 | Usefulness of free prostate specific antigen in the detection of prostate cancer显示文摘 | Axocar G Castillo O Van-Caawelacrt R | 1999 | Reu Med Chil1999，127，2： | 1 |
| 19 | Agricultural water management and poverty linkages显示文摘 | Namara R E Hanjra M A Castillo G E | 2010 | Agricultural Water Management2010，97，4： | 1 |
| 20 | Nitric oxide-related braindamage in acute ischemic stroke 显示文摘 | Castillo J Rama R Ddvalos A | | Stroke^00031 (4):852 -8570，，4： | 1 |
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