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| 1 | Blood loss,predictors of bleeding,transfusion practice and strategies of blood cell salvaging during liver transplantation显示文摘Blood loss during liver transplantation (OLTx) is a common consequence of pre-existing abnormalities of the hemostatic system,portal hypertension with multiple collateral vessels,portal vein thrombosis,previous abdominal surgery,splenomegaly,and poor 'functional' recovery of the new liver.The intrinsic coagulopathic features of end stage cirrhosis along with surgical technical difficulties make transfusion-free liver transplantation a major challenge,and,despite the improvements in understanding of intraoperative coagulation profiles and strategies to control blood loss,the requirements for blood or blood products remains high.The impact of blood transfusion has been shown to be significant and independent of other well-known predictors of posttransplant-outcome.Negative effects on immunomodulation and an increased risk of postoperative complications and mortality have been repeatedly demonstrated.Isovolemic hemodilution,the extensive utilization of thromboelastogram and the use of autotransfusion devices are among the commonly adopted procedures to limit the amount of blood transfusion.The use of intraoperative blood salvage and autologous blood transfusion should still be considered an important method to reduce the need for allogenic blood and the associated complications.In this article we report on the common preoperative and intraoperative factors contributing to blood loss,intraoperative transfusion practices,anesthesiologic and surgical strategies to prevent blood loss,and on intraoperative blood salvaging techniques and autologous blood transfusion.Even though the advances in surgical technique and anesthetic management,as well as a better understanding of the risk factors,have resulted in a steady decrease in intraoperative bleeding,most patients still bleed extensively.Blood transfusion therapy is still a critical feature during OLTx and various studies have shown a large variability in the use of blood products among different centers and even among individual anesthesiologists within the same center.Unfortunately,despite the large number of OLTx performed each year,there is still paucity of large randomized,multicentre,and controlled studies which indicate how to prevent bleeding,the transfusion needs and thresholds,and the 'evidence based' perioperative strategies to reduce the amount of transfusion. | Feltracco Paolo Brezzi Marialuisa Barbieri Stefania Galligioni Helmut Milevoj Moira Carollo Cristiana Ori Carlo | 2013 | World Journal of Hepatology2013，5，1： | 37 |
| 2 | Early respiratory complications after liver transplantation显示文摘The poor clinical conditions associated with end-stage cirrhosis,pre-existing pulmonary abnormalities,and high comorbidity rates in patients with high Model for End-Stage Liver Disease scores are all well-recognized factors that increase the risk of pulmonary complications after orthotopic liver transplantation(OLT)surgery.Many intraoperative and postoperative events,such as fluid overload,massive transfusion of blood products,hemodynamic instability,unexpected coagulation abnormalities,renal dysfunction,and serious adverse effects of reperfusion syndrome,are other factors that predispose an individual to postoperative respiratory disorders.Despite advances in surgical techniques and anesthesiological management,the lung may still suffer throughout the perioperative period from various types of injury and ventilatory impairment,with different clinical outcomes.Pulmonary complications after OLT can be classified as infectious or non-infectious.Pleural effusion,atelectasis,pulmonary edema,respiratory distress syndrome,and pneumonia may contribute considerably to early morbidity and mortality in liver transplant patients.It is of paramount importance to accurately identify lung disorders because infectious pulmonary complications warrant speedy and aggressive treatment to prevent diffuse lung injury and the risk of evolution into multisystem organ failure.This review discusses the most common perioperative factors that predispose an individual to postoperative pulmonary complications and these complications’early clinical manifestations after OLT and influence on patient outcome. | Paolo Feltracco Cristiana Carollo Stefania Barbieri Tommaso Pettenuzzo Carlo Ori | 2013 | World Journal of Gastroenterology2013，19，48： | 32 |
| 3 | Intensive care management of liver transplanted patients显示文摘Advances in pre-transplant treatment of cirrhosis-related organ dysfunction,intraoperative patient management,and improvements in the treatment of rejection and infections have made human liver transplantation an effective and valuable option for patients with end stage liver disease.However,many important factors,related both to an increasing 'marginality' of the implanted graft and unexpected perioperative complications still make immediate post-operative care challenging and the early outcome unpredictable.In recent years sicker patients with multiple comorbidities and organ dysfunction have been undergoing Liver transplantation;appropriate critical care management is required to support prompt graft recovery and prevent systemic complications.Early post-operative management is highly demanding as significant changes may occur in both the allograft and the 'distant' organs.A functioning transplanted liver is almost always associated with organ system recovery,resulting in a new life for the patient.However,in the unfortunate event of graft dysfunction,the unavoidable development of multi-organ failure will require an enhanced level of critical care support and a prolonged ICU stay.Strict monitoring and sustainment of cardiorespiratory function,frequent assessment of graft performance,timely recognition of unexpected complications and the institution of prophylactic measures to prevent extrahepatic organ system dysfunction are mandatoryin the immediate post-operative period.A reduced rate of complications and satisfactory outcomes have been obtained from multidisciplinary,collaborative efforts,skillful vigilance,and a thorough knowledge of pathophysiologic characteristics of the transplanted liver. | Paolo Feltracco Stefania Barbieri Helmut Galligioni Elisa Michieletto Cristiana Carollo Carlo Ori | 2011 | World Journal of Hepatology2011，3，3： | 13 |
| 4 | Interventional radiology procedures in adult patients who underwent liver transplantation显示文摘Interventional radiology has acquired a key role in every liver transplantation(LT)program by treating the majority of vascular and non-vascular post-transplant complications,improving graft and patient survival and avoiding,in the majority of cases,surgical revision and/or re-transplantation.The aim of this paper is to review indications,technical consideration,results achievable and potential complications of interventional radiology procedures after deceased donor LT and living related adult LT. | Roberto Miraglia Luigi Maruzzelli Settimo Caruso Mariapina Milazzo Gianluca Marrone Giuseppe Mamone Vincenzo Carollo Salvatore Gruttadauria Angelo Luca Bruno Gridelli | 2009 | World Journal of Gastroenterology2009，15，6： | 11 |
| 5 | Multidisciplinary imaging of liver hydatidosis显示文摘Liver hydatidosis is a parasitic endemic disease affecting extensive areas in our planet,a significant stigma within medicine to manage because of its incidence,possible complications,and diagnostic involvements.The diagnosis of liver hydatidosis should be as fast as possible because of the relevant complications that may arise with disease progression,involving multiple organs and neighboring structures causing disruption,migration,contamination.The aim of this essay is to illustrate the role of imaging as ultrasonography(US),multi detector row computed tomography,and magnetic resonance imaging(MRI)in the evaluation of liver hydatidosis:the diagnosis,the assessment of extension,the identification of possible complications and the monitoring the response to therapy.US is the screening method of choice.Computed tomography(CT)is indicated in cases in which US is inadequate and has high sensitivity and specificity for calcified hydatid cysts.Magnetic resonance is the best imaging procedure to demonstrate a cystic component and to show a biliary tree involvement.Diagnostic tests such as CT and MRI are mandatory in liver hydatidosis because they allow thorough knowledge regarding lesion size,location,and relations to intrahepatic vascular and biliary structures,providing useful information for effective treatment and decrease in post-operative morbidity.Hydatid disease is classified into four types on the basis of their radiologic appearance. | Gianluca Marrone Francesca Crino' Settimo Caruso Giuseppe Mamone Vincenzo Carollo Mariapina Milazzo Salvatore Gruttadauria Angelo Luca Bruno Gridelli | 2012 | World Journal of Gastroenterology2012，18，13： | 10 |
| 6 | Dexmedetomidine: a re- view of clinical applications显示文摘 | Carollo DS Nossaman BD Ramadhyani U | 2008 | Curr Opin Anaesthesiol2008，21，4： | 1 |
| 7 | Dexmedetomidiue : a re- view of clinical applications 显示文摘 | Carollo DS Nossaman BD Ramadhyani U | 2008 | Curr Opin A naesthesion2008，21，4： | 1 |
| 8 | Dexmedetomidine : a review of clinical applications显示文摘 | Carollo DS Nossaman BD Ramadhyani U | 2008 | Curr OpiAnaesthesiol2008，21，4： | 1 |
| 9 | Dexmedetomidine: a review of clinical applications显示文摘 | Carollo DS Nossaman BD Ramadhyani U | 2008 | Curr Opin Anaesthesiol2008，21，4： | 1 |
| 10 | Dexmedetomidine: clinical application as an adjunct for intravenous regional anesthesia显示文摘 | RAMADHYANI U PARK J L CAROLLO D S | 2010 | Anesthesiot Clin2010，28，4： | 1 |
| 11 | Dexmedetomidine: a review of clinical applications显示文摘 | Carollo DS Nossaman BD Ramadhyani U | 2008 | Curt Opin Anaesthesiol2008，21，4： | 1 |
| 12 | Analysis of organophos-phorus pesticides by gas chromatography- mass spectrometry with negative chemical ionization: a study on the ionization conditions显示文摘 | Amendola L Botre F Carollo A S | 2002 | Anal Chim Acta2002，461，： | 1 |
| 13 | Dexmedetomidine: a review of clinical applications 显示文摘 | Carollo D S Nossaman B D Ramadhyani U | 2008 | Curr Opin Anaesthesiol2008，21，4： | 1 |
| 14 | Dexmedetomidine: a review of clinical applications显示文摘 | Carollo DS Nossaman BD Ramadhyani U | 2008 | Curt Opin Anaesthesiol2008，21，4： | 1 |
| 15 | Dihydropyrimidine dehydrogenase deficiency in an Indian population显示文摘 | Muhammad Wasif Saif Lori Mattison Tom Carollo Hany Ezzeldin Robert B. Diasio | 2006 | Cancer Chemotherapy and Pharmacology2006，，3： | 1 |
| 16 | Flow velocity measurements in vegetated channels显示文摘 | Carollo F G Ferro V Termini D | 2002 | Journal of Hydraulic Engineering2002，128，7： | 1 |
| 17 | Hydroxycinnamic acids as markers of Italian blood orange juices显示文摘 | RAPISARDA P CAROLLO G FALLICO B | 1998 | Journal of Agricultural and Food Chemistry1998，46，27： | 1 |
| 18 | 查看详情显示文摘 | Carollo A C M Pachos J K | | 0，，： | 1 |
| 19 | Dexmedetomidine:a review of clinical applica- tions 显示文摘 | Carollo DS Nossaman BD Ramadhyani U | 2008 | Curt Opin Anaesthesiol2008，21，4： | 1 |
| 20 | Dexmedetomidine: a review of clinical applications 显示文摘 | Carollo DS Nossaman BD Ramadhyani U | 2008 | Curr Opin Anaesthesio12008，21，4： | 1 |
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