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| 1 | Lipid-dependent conformational dynamics underlie the functional versatility of T-cell receptor显示文摘T 房间 receptor-CD3 建筑群(TCR ) 是能基于 CD3 细胞质的领域的各种各样的生物化学的变化开始抗原特定的有免疫力的回答的一台万用的发信号机器,但是内在的结构的基础留下逃犯。这里,我们开发了生物物理的途径学习 CD3 细胞质的领域的 conformational 动力学(CD3 CD ) 。在单个分子的水平,我们发现那 CD3 CD 能与三个功能的主题的不同坦诚有多重 conformational 状态,即, ITAM, BRS 和 PRS。因为,这些符合构造被产生 CD3 CD 有异构的类脂化合物绑定性质因此有异构的动力学。实时房间的成像实验证明不同抗原刺激能稳定 CD3 在不同符合构造的 CD 。类脂化合物依赖者 conformational 动力学因此为 TCR 的万用的发信号性质提供结构的基础。 | Xingdong Guo Chengsong Yan Hua Li Wenmao Huan Xiaoshan Shi Min Huang Yingfang Wang Weiling Pan Mingjun Cai Lunyi Li Wei Wu Yibing Bai Chi Zhang Zhijun Liu Xinyan Wang Xiaohui F Zhang Chun Tang Hongda Wang Wanli Liu Bo Ouyang Catherine C Wong Yi Cao Chenqi Xu | 2017 | Cell Research2017，27，4： | 5 |
| 2 | Effect of EM Bokashi application on control of secondary soil salinization显示文摘In order to ameliorate saline-alkaline soil, EM Bokashi has been applied to rice production in conjunction with subdrainage in Ningxia Autonomous Region and Zhejiang Province. The preliminary results can be summarized as follows: EM Bokashi can increase soil organic matter content, improve soil porosity and permeability, and raise the soil's levels of available nutrients; and EM Bokashi combined with subdrainage treatment is more effective in controlling secondary soil salinization and raising the grain yield and quality than other treatments. The results suggest that EM Bokashi can reduce the necessary amount of chemical fertilizer application, thereby improving the agricultural environment, and that the introduction of EM Bokashi into systems of secondary soil salinization control systems has resulted in significant benefits. | Shao Xiaohou Tan Min Jiang Ping Cao Weiling | 2008 | Water Science and Engineering2008，1，4： | 3 |
| 3 | The C_(6)D_(6)detector system on the Back-n beam line of CSNS显示文摘Introduction The neutron capture cross sections are very important in the field of nuclear device design and basic physics research.Hydrogen-free liquid scintillator such as C_(6)D_(6)detectors are widely used in the neutron capture cross-sectional measurements for the low neutron sensitivity and fast time response.The Back-n white neutron source at China Spallation Neutron Source is the first spallation white neutron source in China,and it is suitable for neutron capture cross-sectional measurement.Materials and methods A C_(6)D_(6)detector system was built in the Back-n experimental station.The pulse height weighting technique was used to determine the system’s detection efficiency.The response to gamma rays of the C_(6)D_(6)detector was measured,and the energy resolution function was determined.Monte Carlo simulation with Geant4 code was carried out to get the weighting function of this C_(6)D_(6)detector system.Additionally,the systematic uncertainty of the weighting function was also determined.Conclusion According to the experimental and simulation results,this C_(6)D_(6)detector system can be used to measure neutron capture cross section. | Jie Ren Xichao Ruan Jie Bao Guangyuan Luan Wei Jiang Qi An Huaiyong Bai Ping Cao Qiping Chen Yonghao Chen Pinjing Cheng Zengqi Cui Ruirui Fan Changqing Feng Minhao Gu Fengqin Guo Changcai Han Zijie Han Guozhu He Yongcheng He Yuefeng He Hanxiong Huang Weiling Huang Xiru Huang Xiaolu Ji Xuyang Ji Haoyu Jiang Hantao Jing Ling Kang Mingtao Kang Bo Li Lun Li Qiang Li Xiao Li Yang Li Yang Li Rong Liu Shubin Liu Xingyan Liu Yinglin Ma Changjun Ning Binbin Qi Zhaohui Song Hong Sun Xiaoyang Sun Zhijia Sun Zhixin Tan Hongqing Tang Jingyu Tang Pengcheng Wang Qi Wang Taofeng Wang Yanfeng Wang Zhaohui Wang Zheng Wang Jie Wen Zhongwei Wen Qingbiao Wu Xiaoguang Wu Xuan Wu Likun Xie Yiwei Yang Han Yi Li Yu Tao Yu Yongji Yu Guohui Zhang Jing Zhang Linhao Zhang Liying Zhang Qingmin Zhang Qiwei Zhang Xianpeng Zhang Yuliang Zhang Zhiyong Zhang Yingtan Zhao Liang Zhou Zuying Zhou Danyang Zhu Kejun Zhu Peng Zhu | 2019 | Radiation Detection Technology and Methods2019，3，3： | 1 |
| 4 | Vasopressor agents for cardiopulmonary resuscitation显示文摘 | Cao L Weil MH Sun S | 2003 | Cardiovasc Pharmacol Ther2003，8，： | 1 |
| 5 | Time-varying network tomography: router link data 显示文摘 | CAO J DAVIS D vander WEIL S | 2000 | Journal of the American Statistical Association2000，95，452： | 1 |
| 6 | Time-varying network tomography:router link data显示文摘 | CAO J DAVIS D WEIL S V | 2000 | Journal of American Statistics Association2000，95，452： | 1 |
| 7 | Time-Varying Network Tomography显示文摘 | CAO J DAVIS D VANDER WEIL S | 2000 | Journal of the American Statistical Association2000，95，452： | 1 |
| 8 | The analysis of a plane wave pseudopotential density functional theory code on a GPU machine显示文摘 | Jia Weile Cao Zongyan Wang Long | 2013 | Computer Physics Communica- tions2013，184，1： | 1 |
| 9 | Vasopressor agents for cardiopulmonary resuscitation 显示文摘 | Cao L Weil MH Sun S | 2003 | Cardiovasc Pharmacol Ther2003，8，： | 1 |
| 10 | Time-varying network tomography:router rink data显示文摘 | Cao J Davis D Weil SV Yu B | 2000 | Journal of American Statistics Association2000，95，452： | 1 |
| 11 | Time-varying network tomography: router link data 显示文摘 | CAO Jin DAVIS D WEIL S V | 2000 | Journal of American Statistics Association2000，95，452： | 1 |
| 12 | Vasopressor agents for cardiopulmonary resuscitation 显示文摘 | Cao L Weil MH Sun S | 2003 | Cardiovasc Pharmacol Ther2003，8，2： | 1 |
| 13 | Time-vary- ing Network Tomography: router link data显示文摘 | CAO J DAVIS D WEIL S V | 2000 | Journal of the American Statistical Association2000，95，： | 1 |
| 14 | Vasopressor agents for cardiopulmonary resuscitation 显示文摘 | Cao L Weil MH Sun S | 2003 | J Cardiovasc Pharmacol Ther2003，8，2： | 1 |
| 15 | Vasopressor agents for cardfopulmonary resuscitation显示文摘 | Cao L Weil MH Sun S | 2003 | Cardiovasc Pharmacol Ther2003，8，2： | 1 |
| 16 | Expression of Key Steroidogenic Enzymes in Human Placenta and Associated Adverse Pregnancy Outcomes显示文摘Steroid hormones,including progestagens,estrogens,androgens,corticosteroids,and their precursor cholesterol,perform essential functions in the successful establishment and maintenance of pregnancy and normal fetal development.As the core endocrine organ at the prenatal stage,the human placenta is involved in the biosynthesis,metabolism,and delivery of steroid hormones.Steroidogenic pathways are tightly regulated by placenta-intrinsic cytochrome P450 and hydroxysteroid dehydrogenase.However,the relationship between placental steroidogenic enzyme expression and adverse pregnancy outcomes is controversial.In this review,we summarize the possible upstream regulatory mechanisms of placental steroidogenic enzymes in physiologic and pathophysiologic states.We also describe the human placental barrier model and examine the potential of single-cell sequencing for evaluating the primary functions and cellular origin of steroidogenic enzymes.Finally,we examine the existing evidence for the association between placental steroidogenic enzyme dysregulation and adverse pregnancy outcomes. | Jiasong Cao Yixin Wang Shuqi Wang Yongmei Shen Wen Li Zhuo Weil Shanshan Li Qimei Lin Ying Chang | 2023 | Maternal-Fetal Medicine2023，5，3： | 0 |
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