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| 1 | Potential beneficial effects of butyrate in intestinal and extraintestinal diseases显示文摘The multiple beneficial effects on human health of the short-chain fatty acid butyrate,synthesized from nonabsorbed carbohydrate by colonic microbiota,are well documented.At the intestinal level,butyrate plays a regulatory role on the transepithelial fluid transport,ameliorates mucosal inflammation and oxidative status,reinforces the epithelial defense barrier,and modulates visceral sensitivity and intestinal motility.In addition,a growing number of studies have stressed the role of butyrate in the prevention and inhibition of colorectal cancer.At the extraintestinal level,butyrate exerts potentially useful effects on many conditions,including hemoglobinopathies,genetic metabolic diseases,hypercholesterolemia,insulin resistance,and ischemic stroke.The mechanisms of action of butyrate are different;many of these are related to its potent regulatory effects on gene expression.These data suggest a wide spectrum of positive effects exerted by butyrate,with a high potential for a therapeutic use in human medicine. | Roberto Berni Canani Margherita Di Costanzo Ludovica Leone Monica Pedata Rosaria Meli Antonio Calignano | 2011 | World Journal of Gastroenterology2011，17，12： | 52 |
| 2 | Probiotics as an emerging therapeutic strategy to treat NAFLD: focus on molecular and biochemical mechanisms显示文摘 | Anna Iacono Giuseppina Mattace Raso Roberto Berni Canani Antonio Calignano Rosaria Meli | 2011 | The Journal of Nutritional Biochemistry2011，，8： | 4 |
| 3 | Design Optimization of Supports for Overhanging Structures in Aluminum and Titanium Alloys by Selective Laser Melting显示文摘 | Calignano F | 2014 | Materials Design2014，64，9： | 1 |
| 4 | Function-al role of high - affinity anandamide transport, as re- vealed by selective inhibition 显示文摘 | Beltramo M Stella N Calignano A | 1997 | Science1997，277，5329： | 1 |
| 5 | A morphological methodology for three dimensional human face soft-tissue landmarks extraction: a pre- liminary study 显示文摘 | Calignano F Vezzetti E | 2011 | Aesthetic Plast Surg2011，35，3： | 1 |
| 6 | Palmitoylethanolamide in CNS health and disase 显示文摘 | Mattaee Raso G Russo R Calignano A | 2014 | Pharmacological Research2014，86，： | 1 |
| 7 | Multiple control of inflammation by glucocorticoids显示文摘 | M. Rosa A. Calignano R. Carnuccio A. Ialenti L. Sautebin | 1986 | Agents and Actions (-)1986，，3： | 1 |
| 8 | Probiotics reduce the inflammatory response induced by a high-fat diet in the liver of young rats 显示文摘 | Esposito E Iacono A Bianco G Autore G Cuzzocrea S Vajro P Canani RB Calignano A Raso GM Meli R | 2009 | J Nutr2009，139，5： | 1 |
| 9 | Control of pain initiation by endogenous cannabinoinds 显示文摘 | Calignano A LaRana G Giuffida A | 1998 | Nature1998，394，15： | 1 |
| 10 | Bidirectional control of airway responsiveness by endogenous cannabinoids显示文摘 | Calignano A Katona I Desarnaud F Giuffrida A La Rana G Mackie K | | 0，，： | 1 |
| 11 | From powders to dense metal parts,Characterization of a commercial AISiMg alloy processed through direct metal laser sintering 显示文摘 | MANFREDI D CALIGNANO F KRISHNAN M | 2013 | Materials2013，6，3： | 1 |
| 12 | NCX-4016:antiinflammatory analgesic antithrombotic显示文摘 | Calignano A Sannicolo F | 1997 | 22(11):1231-12331997，22，11： | 1 |
| 13 | Anti-Inflammatory,analgesic, anti-thrombotic drugs: NCX-4016 显示文摘 | Cirino G Calignano A Sannicolo F | 1992 | Drugs Fur1992，22，11： | 1 |
| 14 | A role for the endogenous cannabinoid system in the peripheral control of pain initiation显示文摘 | Calignano A La Rana G Loubet-lescouli P | 2000 | Prog Brain Res2000，129，1： | 1 |
| 15 | Palmitoylethanolamide in CNS health and disease显示文摘 | Mattace Raso G Russo R Calignano A | 2014 | Pharmacol Res2014，86，： | 1 |
| 16 | The endocannabinoid system as a target for therapeutic drugs显示文摘 | Piomelli D Giuffrida A Calignano A | 2000 | Trends Pharmacol Sci2000，21，6： | 1 |
| 17 | A role for the endogenous cannabinoid system in the peripheral control of pain initiation 显示文摘 | Calignano A La Rana G Loubet-Lescouli P | 2000 | Prog Brain Res2000，129，1： | 1 |
| 18 | Functional role of high-affinity anandamide transport, as revealed by selective inhibition 显示文摘 | Behramo M Stella N Calignano A | 1997 | Science1997，277，： | 1 |
| 19 | Role of innate Immune response in non-alcoholic fatty liver disease: meta- bolic complications and therapeutic tools显示文摘 | MELI R MATTACE R G CALIGNANO A | 2014 | Frontiers in Immunology2014，5，： | 1 |
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