|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Subchronic Oral Cadmium Exposure Exerts both Stimulatory and Suppressive Effects on Pulmonary Inflammation/Immune Reactivity in Rats显示文摘Objective The aim of this study is to investigate the effects of oral cadmium(Cd) ingestion on the pulmonary immune response. Methods Determination of Cd content in lungs and histopathological evaluation of the tissue was performed in rats following 30-day oral Cd administration(5 and 50 mg/L). Antioxidant enzyme defense(superoxide dismutase and catalase), cell infiltration, and production of tumor necrosis factor(TNF) and interferon(IFN)-γ, as well as the activity of myeloperoxidase(MPO), nitric oxide(NO), and various cytokines [interleukin(IL)-1β, IL-6, IL-10, and IL-17] were investigated. Results Cd caused tissue damage and cell infiltration in the lungs, and this damage was more pronounced at higher doses. Cd deposition resulted in lung inflammation characterized by a dose-dependent IL-1β increase in lung homogenates, increased TNF levels at both doses, and IL-6 stimulation at low doses with inhibition observed at higher doses. Cd exerted differential effects on lung leukocytes isolated by enzyme digestion, and these effects were characterized by a lack of change in the production of reactive oxygen and nitrogen species, an inhibition of IL-1β and TNF, and stimulation of MPO and IFN-γ. The higher capacity of Cd-exposed lung cells to respond to the opportunistic pathogen Staphylococcus epidermidis was demonstrated in vitro. Conclusion The potential of ingested Cd to exert both proinflammatory and immunosuppressive effects on pulmonary tissue inflammation and immune reactivity highlights the complex immunomodulatory actions of this metal. | KULAS Jelena NINKOV Marina TUCOVIC Dina POPOV Aleksandrov Aleksandra UKROPINA Mirela CAKIC MILOSEVIC Maja MUTIC Jelena KATARANOVSKI Milena MIKROV Ivana | 2019 | Biomedical and Environmental Sciences2019，32，7： | 4 |
| 2 | Effects of the acrylic polyol structure and the selectivity of the employed catalyst on the performance of two-component aqueous polyurethane coatings 显示文摘 | Cakic S Lacnjevac C Stamenkovic J | 2007 | Sensors2007，7，： | 1 |
| 3 | Effects of the acrylic polyol structureand the selectivity of the employed catalyst on the performance of two-component aqueous polyurethane coatings显示文摘 | Cakic S Lacnjevac C Stamenkovic J | 2007 | Sensors2007，7，5： | 1 |
| 4 | 显示文摘 | Suzana M Cakic Ivan S Ristic Vladislav M J aso | 2012 | Pro- gress in Organic Coatings2012，73，4： | 1 |
| 5 | Synthesis and degradation profile of cast fihns of PPG - DMPA - IPDI aqueous pol- yurethane dispersions based on selective catalysts显示文摘 | SUZANA M CAKIC JAKOV V STAMENKOVIC | 2009 | Polymer Deg- radation and Stability2009，94，11： | 1 |
| 6 | Synthesis and degradation profile of cast films of PPG-DMPA-IPDI aqueous polyurethane dispersions based on selective catalysts 显示文摘 | Cakic S M Stamenkovic J V Djordjevic D M | 2009 | Polymer Degradation and Stability2009，94，11： | 1 |
| 7 | The effects of the Marinovic-Cincovic M, structure and molecular weight of the macrodiol on the properties polyurethane anionic adhesives显示文摘 | Cakic S M Ristic I S | 2013 | International Journal of Adhesion and Adhesives2013，41，： | 1 |
| 8 | Synthesis and degradation profile of cast films of PPG-DMPA-IPDI aqueous polyurethane dispersions based on selective catalysts 显示文摘 | Cakic S M Stamenkovic J V Djordjevic D M | 2009 | Polymer Degradation and Stability2009，94，11： | 1 |
| 9 | The waterborne polyurethane dispersions based on polycarbonate diol: Effect of ionic content 显示文摘 | Cakic S M Milena Ristic S I | 2013 | Materials Chemistry and Physics2013，38，1： | 1 |
| 10 | Synthesisand degradation profile of cast films of PPG - DMPA - IPDI aqueous polyure- thane dispersions based on selective cata- lysts 显示文摘 | Suzana M Cakic Jakov V Stamenkovic Dragan M Djordjevic | 2009 | Polymer Degradation Stability2009，94，11： | 1 |
| 11 | The effects of the structure and molecular weight of the macrodiol on the properties polyurethane anionic adhesives 显示文摘 | CAKIC S M RISTIC I S MARINOVIC-CINCOVIC M | 2013 | International Journal of Adhesion and Adhesives2013，41，： | 1 |
| 12 | The effects of the structure and molecular weight of the maerodiol on the p,'operlies polyurethane anionic adhesives 显示文摘 | CAKIC S M RISTIC 1 S MARINOVIC-CINCOVIC M | 2013 | International Journal of Adhesion and Adhesives2013，，41： | 1 |
| 13 | The waterborne polyurethane dispersions based on polycarbonate diol:Effect of ionic content显示文摘 | Cakic S M Spirkova M Ristic I S | 2013 | Materials Chemistry and Physics2013，138，1： | 1 |
| 14 | Glycolyzed poly(ethylene terephthalate) waste and castor oil-based polyols for waterborne polyurethane adhesives containing hexamethoxymethyl melamine 显示文摘 | CAKIC S M RISTIC I S CINCOVIC M M | 2015 | Progress in Organic Coatings2015，78，： | 1 |
| 15 | Salivary antioxidants as periodontal biomarkers in evaluation of tissue status and treatment outcome显示文摘 | N. Novakovic T. Todorovic M. Rakic I. Milinkovic I. Dozic S. Jankovic Z. Aleksic S. Cakic | 2014 | J Periodont Res2014，，1： | 1 |
| 16 | Synthesis and degradation profile of cast films of PPG-DMPA-IPDI aqueous polyurethane dispersions based on selective catalysts显示文摘 | Suzana M Cakic Jakov V Stamenkovic Dragan M Djordjevic | 2009 | Polymer Degradation and Stability2009，94，11： | 1 |
| 17 | Catalysis of the isocyanate-hidroxyl reaction by non-tin catalysts in water borne two component polyurethane coatings显示文摘 | STAMENKOVIC J CAKIC S KONSTANTINOVIC S | 2004 | Facta Universitatis-Series:Working and Living Environmental Protection2004，2，4： | 1 |
| 18 | Gingival crevicular fluid in the diagnosis of periodontaland systemic diseases 显示文摘 | CakicS | 2009 | Srp Arh Celok Lek2009，137，56： | 1 |
| 19 | Periodontal Therapy Improves Gastric Helicobacter pylori Eradication显示文摘 | Zaric S Bojic B Jankovic Lj Dapcevic B Popovic B Cakic S Milasin J | 2009 | Journal of Dental Research2009，，10： | 1 |
| 20 | Fast fourier transform IR characterization of epoxy GY systems crosslinked with aliphatic and cyeloaliphatie EH polyamine adducts显示文摘 | NIKOLIC G ZLATKOVIC S CAKIC M | 2010 | Sen- sors2010，10，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员