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| 1 | Role of gut microbiota in cardiovascular diseases显示文摘The human gut is colonized by a community of microbiota,primarily bacteria,that exist in a symbiotic relationship with the host.Intestinal microbiota-host interactions play a critical role in the regulation of human physiology.Deleterious changes to the composition of gut microbiota,referred to as gut dysbiosis,has been linked to the development and progression of numerous diseases,including cardiovascular disease(CVD).Imbalances in host-microbial interaction impair homeostatic mechanisms that regulate health and can activate multiple pathways leading to CVD risk factor progression.Most CVD risk factors,including aging,obesity,dietary patterns,and a sedentary lifestyle,have been shown to induce gut dysbiosis.Dysbiosis is associated with intestinal inflammation and reduced integrity of the gut barrier,which in turn increases circulating levels of bacterial structural components and microbial metabolites,including trimethylamine-N-oxide and short-chain fatty acids,that may facilitate the development of CVD.This article reviews the normal function and composition of the gut microbiome,mechanisms leading to the leaky gut syndrome,its mechanistic link to CVD and potential novel therapeutic approaches aimed towards restoring gut microbiome and CVD prevention.As CVD is the leading cause of deaths globally,investigating the gut microbiota as a locus of intervention presents a novel and clinically relevant avenue for future research. | Marko Novakovic Amit Rout Thomas Kingsley Robert Kirchoff Amteshwar Singh Vipin Verma Ravi Kant Rahul Chaudhary | 2020 | World Journal of Cardiology2020，12，4： | 6 |
| 2 | 添加凹凸棒黏土对生物质固体成型燃料抗结渣性的影响显示文摘针对当前生物质固体成型燃料抗结渣剂成本高、抗结渣效果差等实际问题,该研究采用凹土作为天然复合添加剂,制备了凹土添加量为0~7%的生物质固体成型燃料,并对其进行了工业分析及高位热值测定。燃烧生物质固体成型燃料获得灰样,采用高速相机采集灰样宏观形貌,采用扫描电镜(Scanning Electron Microscope,SEM)对灰样微观形貌进行分析。最后借助X荧光(X-ray Fluorescence,XRF)、X射线衍射(X-ray Diffraction,XRD)对生物质灰成分进行确定,以分析凹土抗结渣机理。结果表明,凹土添加量为3%以下时,热值下降速度较小,但灰分随凹土添加量增大而增加较快。由宏观形貌和微观形貌谱图发现,凹土可以极好地提升生物质固体成型燃料抗结渣性,这主要是因为添加凹土后,凹土改变了K的迁移途径,生成了更多KAlSiO_(4)、KAlSi_(2)O_(6)、Ca_(2)Mg(Si_(2)O_(7))等高熔点的复盐。该研究可为解决生物质固体成型燃料行业缺乏高效低成本抗结渣剂问题提供良好解决方案。 | 李发达 李金平 王志峰 王金明 Vojislav Novakovic | 2022 | 农业工程学报2022，38，6： | 2 |
| 3 | 寒冷地区空气源热泵辅助太阳能热水器供暖性能显示文摘为提高太阳能热水器供暖的稳定性并大幅降低空气源热泵供暖的成本,提出空气源热泵辅助太阳能真空管热水器供暖构想,在甘肃省兰州市七里河区魏岭乡绿化村搭建空气源热泵辅助太阳能热水器供暖试验系统,详细研究了晴天、阴天及多云3种典型工况下系统的集热效率、热泵性能系数、系统太阳能保证率和系统能效比等.研究结果表明,晴天、阴天及多云工况下太阳能集热器有效得热量分别为75.5、4.1和49.2 kW·h,集热效率分别为61.3%、26.6%、55.2%,太阳能热泵平均性能系数(COP)分别为3.6、3.4、3.6,空气源热泵平均COP分别为0、2.9、3.1,系统实际供热量分别为113.4、125.9和124.8 kW·h,系统耗电量分别为33.4、50.5和42.7 kW·h,系统太阳能保证率分别为66.6%、3.3%、39.4%,系统能效比分别为3.4,2.5,2.9.研究证明了太阳能真空管集热器-空气源热泵系统用于寒冷地区供暖的可行性,为寒冷地区供暖提供了一种新途径. | 李金平 董玉慧 李彩军 代静波 牛轶男 NOVAKOVIC Vojislav | 2023 | 上海交通大学学报2023，57，7： | 2 |
| 4 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 5 | Bioreact or cultivationconditions modulate the composition and mechanical properties of tissue-engineering cartlage显示文摘 | VUNJAK Novakovic G MARTIN I OBRADOVIC B | 1999 | J Orthop Res1999，17，1： | 1 |
| 6 | Dynamic cell seeding of polymer scaffolds for cartilage tissue engineering显示文摘 | Obradovic B Martin I | 1998 | Biotechnol Prog1998，14，2： | 1 |
| 7 | Dynamic cell seeding of polymer scaffolds for cartilage tissue engineering显示文摘 | Vunjak Novakovic G Obradovic B Martin I | 1998 | Biotechnol Prog1998，14，2： | 1 |
| 8 | The immunohistochemical and serological of p53 protein in patients with maligant lyphomas 显示文摘 | Jezersek Novakovic B Frkovic Grazio S Novakovic S | 2002 | Neoplasma2002，49，1： | 1 |
| 9 | Stem cell-based tissue engineering with silk biomaterials 显示文摘 | Wang Y Z Kim H J Novakovic G V | 2006 | Biomaterials2006，27，36： | 1 |
| 10 | The effects of Bestradiol on SHSY5Y neuroblastoma cells during heavy induced oxidative stress, neurotoxicity and B--amyloid secretion显示文摘 | Olivieri G Novakovic M Savaskan E | 2002 | Neuroscience2002，113，4： | 1 |
| 11 | Clinical staging and histopathological findings after radical hysterectomy in FIGO stage IIB cervical cancer显示文摘 | Mandic A Novakovic P Mihajlovic O | 2008 | J BUON2008，13，1： | 1 |
| 12 | XAFS studies of nickel-doped lead telluride 显示文摘 | Radisavljevic I Novakovic N N Ivanovic | 2009 | Physica B: Condensed Matter2009，404，2324： | 1 |
| 13 | Immunocytochemical localization of P2X3 purinoceptors in sensory neurons in naive rats and following neuropathic injury显示文摘 | Novakovic S D Kassotakis L C Oglesby I B | 1999 | Paty1999，80，12： | 1 |
| 14 | Cloud condensation nucleus activity of organic compounds: a laboratory study 显示文摘 | CORRIGAN C E NOVAKOV T | 1999 | Atmospheric Environment1999，33，： | 1 |
| 15 | Large Contribution of Organic Aerosols to Cloud-condensation Nuclei Concentrations显示文摘 | Novakov T Penner J E | 1993 | Nature1993，365，： | 1 |
| 16 | Immunocytochemical localization of P2X3 purinoceptors in sensory neurons in naive rats and following neuropathie injury显示文摘 | Novakovic SD Kassotakis LC Oqlesby IB | 1999 | Pain1999，80，12： | 1 |
| 17 | Electroless NiP-TiOz composite coatings: Their production and properties 显示文摘 | NOVAKOVIC J VASSILIOU P SAMARA K L | 2006 | Surface Coating Technology2006，201，34： | 1 |
| 18 | Vacuum heated electroless nickel plated contacts 显示文摘 | DERVOS C T VASSILIOU P NOVAKOVIC J | 2004 | IEEE Trans Compon Packag Technology2004，27，1： | 1 |
| 19 | An Analytic Ap-proach to Fuzzy Robot Control Synthesis显示文摘 | Scap D Novakovic D | 2000 | Artifi-cial Intelligence2000，13，： | 1 |
| 20 | Combined effect of CYP1B1,COMT,GSTP1,and MnSOD genotypes and risk of postmenopausal breast cancer显示文摘 | CERNE J Z POHAR PERME M NOVAKOVIC S | | 0，，02： | 1 |
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