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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Determinants of individual engagement in knowledge sharing显示文摘 | Cabrera A Collins W C Salgado J F | 2006 | International Journal of HumanResource Management2006，17，2： | 1 |
| 3 | The identification of KRAS mutations at eodon 12 in plasma DNA is not a prognostic fac- tor in advanced non-small cell lung cancer patients显示文摘 | Camps C Jantus-Lewintre E Cabrera A | 2011 | Lung Canc- er2011，72，3： | 1 |
| 4 | Beneficial effects ofgreen tea-a review 显示文摘 | Cabrera C Artacho R Giménez R | 2006 | Journal of the American College ofNutrition2006，25，2： | 1 |
| 5 | Mapping sugar beet pectin acetylation B pattern 显示文摘 | Ralet M C Cabrera J C Bonnin E | 2005 | Phytochernistry2005，66，15： | 1 |
| 6 | Usefulness of anorectal manometry in the neonatal diagnosis of Hirschsprung disease显示文摘 | Nunez R Cabrera R Moreno C | | 0，，01： | 1 |
| 7 | Treatment of ureteral lithiasis with shock waves显示文摘 | Gonzalez Enquita C Cabrera Perez J Calahorra Fernandez F J | 2001 | Arch Esp Urol2001，54，9： | 1 |
| 8 | The essential oil of Senecio graveolens(Compositae) : Chemical composition and antimicrobial activity tests 显示文摘 | PEREZ C AGNESE A M CABRERA J L | 1999 | Journal of Ethnopharmacology1999，66，2： | 1 |
| 9 | Early hematopoietic recovery after single unit unrelated cord blood transplantation in adults supported by co-infusion of mobilized stem cells from a third party donor显示文摘 | Magro E Regidor C Cabrera R | 2006 | Haematologica2006，91，5： | 1 |
| 10 | Electrochemical and surface analysis study of copper corrosion protection by 1 & hyphen;propanethiol and propyltrimethoxysilane & colon; A comparison with 3 & hyphen; mercaptopropyltrimethoxysilane 显示文摘 | Tremont R Cabrera C R | 2002 | Journal of Applied Electrochemistry2002，32，7： | 1 |
| 11 | Acute exercise activates nuclear factor (NF)-kappaB signaling pathway in rat skeletal muscle 显示文摘 | JI L L GOMEZ CABRERA M C STEINHAFEL N | 2004 | FASEB J2004，18，13： | 1 |
| 12 | Improved endotracheal intubation technique in the rat显示文摘 | Pena H Cabrera C | 1980 | Laboratory Anim Sci1980，30，： | 1 |
| 13 | Preparation of carbon molecular sieves,two step hydrocarbon decomposition with a single hydrocarbon显示文摘 | Cabrera A L Zehner J E Coe C G | | 0，，： | 1 |
| 14 | Selenium, copper, zinc, iron and manganese content of seven meat cuts from Hereford and Braford steers fed pas ture in Uruguay 显示文摘 | Cabrera M C Ramos A Saadoun A | 2010 | Meat Science2010，84，3： | 1 |
| 15 | Hot ductility behavior of boron microalloyed steels显示文摘 | LOPEZ-CHIPRES E MEJIA I MALDONADO C BEDOLLA-JACUINDE A CABRERA J M | 2007 | Mat Sci Eng A2007，，： | 1 |
| 16 | Sorption characteristics of heavy metal ions by a natural zeolite 显示文摘 | Cabrera C Gabaldon C Marzal P | 2005 | Journal of Chemical Technology and Biotechnology2005，80，4： | 1 |
| 17 | Short stature is related to high body fat composition despite body mass index in a Mexican population 显示文摘 | L6pez - Alvarenga JC Montesinos - Cabrera RA Vel6zquez - Alva C et at | 2003 | Arch Med Res2003，34，2： | 1 |
| 18 | Human immunodeficiency virus glycoprotein gp120 as the primary target for the antiviral action of AR177 (Zintevir) 显示文摘 | Este JA Cabrera C Schols D | 1998 | Mol Pharmacol1998，53，2： | 1 |
| 19 | Association of cellular adhesion molecules and oxidative stress with endothelial function in obstructive sleep apnea显示文摘 | Jurado-Gamez B Bujalance Cabrera C Caballero Ballesteros L | 2012 | Intern Med2012，51，4： | 1 |
| 20 | Lab-on-a-chip for drug development 显示文摘 | WEIGL B H BARDELL R L CABRERA C R | 2003 | Advanced Drug Delivery Reviews2003，55，3： | 1 |
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