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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Diurnal variations in hydraulic conductivity and root pressure can be correlated with the expression of putative aquaporlns in the roots of Lotus japonicus显示文摘 | HENZLER T WATERHOUSE R N SMYTH A J CARVAJAL M COOKE D T SCHAFFNER A R STEUDLE E CLARKSOND T | 1999 | Planta1999，210，： | 1 |
| 3 | Archive,records,and power:the making of modern memory显示文摘 | Schwartz J M Cook T | 2002 | Archival Science2002，2，12： | 1 |
| 4 | Tetanus显示文摘 | Farrar J J Yen L M Cook T | 2000 | J Neurol Neurosurg Psychiatry2000，69，： | 1 |
| 5 | The ProSeal laryngeal mask airway: a review of the literature显示文摘 | COOK T M LEE G NOLAN J P | 2005 | Can J Anaesth2005，52，7： | 1 |
| 6 | Retention of nitrogen, phosphorus and silicon in a large semi-arid riverine lake system 显示文摘 | Pert'an L Cook M Aldridge K T | 2010 | Biogeochemistry2010，99，13： | 1 |
| 7 | Interelemental relationship in the soil and plant tissue and photosynthesis of field cultivated wheat growing in naturally enriched copper soils 显示文摘 | Vardaka E Cook C M Lanaras T | 1997 | Journal of Plant Nutrition1997，20，1： | 1 |
| 8 | Evidence of compositional differences between the extracellular and intracellular DNA of a granular sludge biofilm 显示文摘 | Cheng M Cook A E Fukushima T | 2011 | Appl Microbiol Lett2011，53，： | 1 |
| 9 | Complement and glomerular disease:new insights显示文摘 | Pickering M Cook H T | 2011 | Curr Opin Nephrol Hypertens2011，20，3： | 1 |
| 10 | Creating open government ecosystems: A research and development agenda 显示文摘 | Harrison T M Pardo T A Cook M | 2012 | Future Internet2012，4，4： | 1 |
| 11 | Isolation and characterization of a cDNA clone encoding rat 5- lipoxygenase显示文摘 | BALCAREK J M THEISEN T W COOK M N | 1988 | J Biol Chem1988，263，13： | 1 |
| 12 | Velocity spectra and their use in stratigraphic and lithologic differentiation显示文摘 | Cook E E Taner M T | 1969 | Geophysical Prospecting1969，17，4： | 1 |
| 13 | Interelemental relationship in the soil and plant tissue and photosynthesis of field cultivated wheat growing in naturally enriched copper soils显示文摘 | Vardake E Cook C M Lanaras T | 1997 | J Plant Nutr1997，20，45： | 1 |
| 14 | Dietary cholesterol stimulates hepatic biosynthesis of triglyceride and reduces oxidation of fatty acids in the rat显示文摘 | Fungwe T V Cagen L M Cook G A | | 0，，： | 1 |
| 15 | Enhanced in- cidence of legabnormalies in reovirus WVU2937 - infected chickens fedvarious dietary levels of select- ed vitamins显示文摘 | Cook M E Sppinger W T Hebert J A | 1983 | Avian Diseases1983，28，3： | 1 |
| 16 | Reduced coronary events in simvastatintreated payients with coronary heart disease and diabetes or impaired fasting glucose levels:subgroup analyses in the Scandinavian Simvastatin Survival Study显示文摘 | Haffner S M Alexander C M Cook T J | 1999 | Arch Intern Med1999，159，22： | 1 |
| 17 | The ProSeal laryngeal mask airway: a review of the literature显示文摘 | COOK T M LEE G NOLAN J P | 2005 | Can J Anaesth2005，52，7： | 1 |
| 18 | A survey of sketch-based 3D modeling techniques 显示文摘 | Cook M T Agah A | 2009 | Interacting with Computers2009，21，3： | 1 |
| 19 | Xenon purity analysis for exo-200 via mass spectrometry 显示文摘 | Dobi A Hall C Slutsky S Yen Y R Aharmin B Auger M Barbeau P S Benitez-Medina C Breidenbach M Cleveland B Conley R Cook J Cook S Counts I Craddock W Daniels T Davis C G Davis J Devoe R Dixit M Dolinski M J Donato K Fairbank Jr W Farine J Fierlinger P Franco D Giroux G Gornea R Graham K Gratta G Green C Hagemann C Hall K Hallman D Hargrove C Herrin S Hughes M Hodgson J Juget F Karelin A Kaufman L J Kuchenkov A Kumar K Leonard D S Lutter G Mackay D Maclellan R Marino M Mong B Montero Diez M Morgan P MUller A R Neilson R Odian A Oullivan K Piepke A Pocar A Prescott C Y Pushkin K Rivas A Rollin E Rowson P C Sabourov A Sinclair D Skarpaas K Stekhanov V Strickland V Swift M Twelker K Vuilleumier J L Vuilleumier J M Weber M Wichoski U Wodin J Wright J D Yang L | 2012 | Nuclear Instruments and Methods in Physics Research Section A: Accelerators Spectrometers Detectors and Associated Equipment2012，675，： | 1 |
| 20 | Improving results of open arch replacement 显示文摘 | SUNDT T M 3rd ORSZULAK T A COOK D J | 2008 | Ann Thorac Surg2008，86，8： | 1 |
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