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| 1 | 1961-2005年宁夏极端降水事件变化趋势分析显示文摘利用1961—2005年宁夏逐日降水量资料,将降水量划分为9个级别,分析了宁夏45a来各级别降水日数的变化趋势。结果表明:年降水量以平均3.6mm/10a的速率减少;近15a来,冬、春季降水量明显减少,夏、秋季10.0mm以下降水日数明显减少,25.0mm以上降水日数明显增加。以1986年为界的气候变暖前后25.1~50.0mm级别的降水日数夏季和年增加的显著性概率分别达到了5%和1%,降水频率分布呈现向高级别降水量增加的变化趋势。 | 陈晓光 Declan Conway 陈晓娟 郑广芬 | 2008 | 气候变化研究进展2008,4,3: | 51 |
| 2 | 1961—2004年宁夏极端气温变化趋势分析显示文摘利用1961—2004年宁夏逐日最高、最低气温资料,分析了宁夏44a来最高、最低气温的变化趋势。结果表明:宁夏的最高、最低气温表现出了明显的变化趋势,最高气温<0℃的日数减少,>30℃的日数增加;在年平均最低气温升高的同时,极冷日数也在增加,相对于1961—1990年的平均值,20世纪90年代和21世纪最初的4a年极冷日数分别增加了1.1d和0.7d,距平百分率分别达350%和275%。 | 陈晓光 Declan Conway 郑广芬 陈晓娟 | 2008 | 气候变化研究进展2008,4,2: | 34 |
| 3 | 澄江化石库中的双胚层动物新知显示文摘作为观察寒武纪大爆发主幕奥秘的最佳科学窗口,澄江化石库展示了三胚层动物(即两侧对称动物)首次全面大辐射的历史产物,让学术界终于看到了已知最古老的同时包括原口类和后口类两大支系的动物谱系庞大“树冠”的主体轮廓,从而给许多较高级动物类群的起源和早期演化研究提供了十分重要的信息。然而,该化石宝库中却很少见到作为“树干”的双胚层动物(即辐射动物)的化石记录,这给“真动物”的源头探秘蒙上了阴影。尽管广布于前寒武纪末期全球浅海域的“文德生物群”一直被认为是动物界早期一次“失败的演化试验”的牺牲品,但其中一支成功延续到早寒武世的春光虫(Stromatoveris)具有叠覆状梳齿构造,很可能代表着栉水母类的一类原始祖先。文中描述新的羽毛状动物王氏澄江海笔(Chengjiangopennawangii)不同于春光虫,前者具有彼此分离的羽枝,且羽枝上保存了排列规整的珊瑚个体虫室,因而与现代八射珊瑚中海笔类的形态学特征十分一致;新的谱系分析显示,它应该代表刺胞动物门中的一个原始类群。 | 舒德干 Simon CONWAY MORRIS | 2006 | 地学前缘2006,13,6: | 7 |
| 4 | Inferring the Tree of Life of the order Cypriniformes, the earth's most diverse clade of freshwater fishes: Implications of varied taxon and character sampling显示文摘The phylogenetic relationships of species are fundamental to any biological investigation, including all evolutionary studies. Accurate inferences of sister group relationships provide the researcher with an historical framework within which the attributes or geographic origin of species (or supraspecific groups) evolved. Taken out of this phylogenetic context, interpretations of evolutionary processes or origins, geographic distributions, or speciation rates and mechanisms, are subject to nothing less than a biological experiment without controls. Cypriniformes is the most diverse clade of freshwater fishes with estimates of diversity of nearly 3,500 species. These fishes display an amazing array of morphological, ecological, behavioral, and geographic diversity and offer a tremendous opportunity to enhance our understanding of the biotic and abiotic factors associated with diversification and adaptation to environments. Given the nearly global distribution of these fishes, they serve as an important model group for a plethora of biological investigations, including indicator species for future cli-matic changes. The occurrence of the zebrafish, Danio rerio, in this order makes this clade a critical component in understanding and predicting the relationship between mutagenesis and phenotypic expressions in vertebrates, including humans. With the tremendous diversity in Cypriniformes, our understanding of their phylogenetic relationships has not proceeded at an acceptable rate, despite a plethora of morphological and more recent mo-lecular studies. Most studies are pre-Hennigian in origin or include relatively small numbers of taxa. Given that analyses of small numbers of taxa for molecular characters can be compromised by peculiarities of long-branch attraction and nodal-density effect, it is critical that significant progress in our understanding of the relationships of these important fishes occurs with increasing sampling of species to mitigate these potential problems. The recent Cypriniformes Tree of Life initiative is an effort to achieve this goal with morphological and molecular (mitochondrial and nuclear) data. In this early synthesis of our understanding of the phylogenetic relationships of these fishes, all types of data have contributed historically to improving our understanding, but not all analyses are complementary in taxon sampling, thus precluding direct understanding of the impact of taxon sampling on achieving accurate phylogenetic inferences. However, recent molecular studies do provide some insight and in some instances taxon sampling can be implicated as a variable that can influence sister group relationships. Other instances may also exist but without inclusion of more taxa for both mitochondrial and nuclear genes, one cannot distinguish between inferences being dictated by taxon sampling or the origins of the molecular data. | Richard L. MAYDEN Kevin L. TANG Robert M. WOOD Wei-Jen CHEN Mary K. AGNEW Kevin W. CONWAY Lei YANG Andrew M. SIMONS Henry L. BART Phillip M. HARRIS Junbing LI Xuzhen WANG Kenji SAITOH Shunping HE Huanzhang LIU Yiyu CHEN Mutstmi NISHIDA Masaki MIYA | 2008 | 植物分类学报2008,46,3: | 5 |
| 5 | Risk of liver disease in methotrexate treated patients显示文摘Methotrexate is the first line drug treatment for anumber of rheumatic and non-rheumatic diseases. It is effective in controlling disease activity and preventing disease-related damage, and significantly cheaper than many alternatives. Use in rheumatoid arthritis infers a significant morbidity and mortality benefit. Methotrexate is generally well tolerated but can cause symptomatic adverse events. Multiple serious adverse events have been attributed to methotrexate, based largely on older reports using high or daily doses, and subsequent case reports and circumstantial evidence. The risk with modern dosing regimens: Lower doses, weekly schedules, and concomitant folic acid is less clear. Clarification and dissemination of the actual risk is crucial so appropriate judgements can be made for patients who may benefit from this treatment. Methotrexate has been associated with a range of liver related adverse events ranging from asymptomatic transaminase elevations to fibrosis and fatal hepatic necrosis. Concern over potential liver toxicity has resulted in treatment avoidance, cessation, or recommendations for investigations which may be costly, invasive and unwarranted. Modern laboratory monitoring of liver blood tests may also influence the risk of more serious complications. The majority of present day studies report an approximate doubling of the relative risk of elevated transaminases in methotrexate treated patients but no increased risk of symptomatic or severe liver related adverse events. In this article we will review the evidence around methotrexate and liver related adverse events. | Richard Conway John J Carey | 2017 | World Journal of Hepatology2017,9,26: | 5 |
| 6 | Current state of endohepatology: Diagnosis and treatment of portal hypertension and its complications with endoscopic ultrasound显示文摘The diagnosis and management of cirrhosis and portal hypertension(PH)with its complications including variceal hemorrhage,ascites,and hepatic encephalopathy continues to evolve.Although there are established“standards of care”in liver biopsy and measurement of PH,gastric varices remain an area without a universally accepted therapeutic approach.The concept of“Endo Hepatology”has been used to describe of the applications of endoscopic ultrasound(EUS)to these challenges.EUS-liver biopsy(EUS-LB)offers an alternative to percutaneous and transjuglar liver biopsy without compromising safety or efficacy,and with added advantages including the potential to reduce sampling error by allowing biopsies in both hepatic lobes.Furthermore,EUS-LB can be performed during the same procedure as EUS-guided portal pressure gradient(PPG)measurements,allowing for the collection of valuable diagnostic and prognostic data.EUS-guided PPG measurements provide an appealing alternative to the transjugular approach,with proposed advantages including the ability to directly measure portal vein pressure.In addition,EUS-guided treatment of gastric varices(GV)offers several possible advantages to current therapies.EUS-guided treatment of GV allows detailed assessment of the vascular anatomy,similar efficacy and safety to current therapies,and allows the evaluation of treatment effect through doppler ultrasound visualization.The appropriate selection of patients for these procedures is paramount to ensuring generation of useful clinical data and patient safety. | Sean R Rudnick Jason D Conway Mark W Russo | 2021 | World Journal of Hepatology2021,13,8: | 4 |
| 7 | 二氧化碳、碳酸氢盐与有机伯胺和仲胺反应机理显示文摘采用停留光谱法和核磁共振(氢谱)法系统地研究了二氧化碳(aq)、碳酸氢盐与一乙醇胺(MEA)、L-氨基丙醇(2-AP)、1-氨基-2-丙醇(1-AP)、N-甲基正丙胺(IBA)、3-氨基丙醇(3-AP)、二乙醇胺(DEA)、吗啉(MORP)、哌啶(PIPD)和4-哌啶甲醇(4-PIPDM)在水溶液中25℃下的反应动力学,阐明其反应机理,给出二氧化碳、碳酸氢盐与有机胺的反应速率常数、氨基甲酸盐质子化常数和氨基甲酸盐的稳定常数。研究发现:二氧化碳与伯胺和仲胺的反应速率常数与其氨基甲酸盐的稳定常数具有线性关系。发现氨基甲酸盐稳定常数代表液态有机胺(氨)分子的空间位阻效应、溶剂化效应和电子效应的协同作用,它对于设计新型液态有机胺分子具有重要理论指导作用。 | 张国辉 王晓光 William Conway Marcel Maeder 孙琦 于海 | 2013 | 化工学报2013,64,8: | 4 |
| 8 | 使用离子束治疗法成功治疗侵入眼内的结膜鳞状上皮细胞癌显示文摘由于长时间的紫外线照射,结膜鳞状上皮细胞癌在世界范围内变得越来越流行。尽管如此,原发结膜鳞状上皮细胞癌侵人眼内仍然十分罕见,因此经常导致误诊。侵及眼部大且侵袭力强的病变仅通过标准的切除手术和冷冻术往往较难治愈。对于这种病变的治疗,大多数研究者会建议行眼球摘除术,当有证据显示病变侵及眼眶时则行眶内容物剜除术^1-4。目前的病例显示使用离子束治疗侵入眼内的结膜鳞状上皮细胞癌是眼球摘除术外的另一种选择。就我们所知,这是第一例关于使用离子束治疗侵袭性结膜鳞状上皮细胞癌的病例报道。 | Krista M. Ramonas R. Max Conway Inder K. Daftari J. Brooks Crawford Joan M. O' Brien 张弛(译) | 2006 | 美国医学会眼科杂志(中文版)2006,18,3: | 3 |
| 9 | The role and utilization of pseudocapacitance for energy storage by supercapacitors显示文摘 | B.E. Conway V. Birss J. Wojtowicz | 1997 | Journal of Power Sources1997,,1: | 3 |
| 10 | Factors influencing time course of pain after depot oil intramuscular injection of testosterone undecanoate显示文摘疼痛追随者仓库肌内(IM ) 油的注射基于车辆的药是学习的很少。这研究试图有希望地在 4-mL 海狸油车辆在 1 000 mg 睾丸激素 undecanoate (TU ) 的 IM 注射以后在这个星期期间决定流行,决定因素,严厉和疼痛的功能的后果。在一个学术 andrology 诊所收到常规 T 代替治疗的雄激素缺乏的人被招募在深 IM 臀的注射以后在第一天和日报在七次用有色的视觉线性类似物规模报导疼痛分数一个星期。时间功课和 covariables 影响疼痛分数被变化(ANOVA ) 的混合模型分析分析。在 125 个人,的追随者 168 注射疼痛被 80% 人报导,在注射以后立即达到顶点,到达仅仅中等的严厉,持续 1 鈥?天并且在白天回到基线 4。疼痛几乎没要求很少止痛使用并且在每日的活动生产了最小的干扰。疼痛分数的时间功课在经历了二连续注射的 43 个人是可再现的。疼痛在有更早痛苦的注射,而是在严重的更少的人是更严重的更旧并且更多的肥胖的人。根据在管理注射的富有经验的护士之间的注射以后的疼痛经验有可以忽略的差别。在 4-mL 海狸油的仓库 TU 的深 IM 臀的注射很好被容忍,注射以后的疼痛被更早痛苦的注射经验,以及年龄和肥胖影响。 | Gideon Sartorius Carolyn Fennell Sasa Spasevska Leo Turner Ann J. Conway David J. Handelsman | 2010 | Asian Journal of Andrology2010,12,2: | 3 |
| 11 | Do adjunctive art therapies reduce symptomatology in schizophrenia? A meta-analysis显示文摘BACKGROUND Art therapies are advocated by national bodies,such as the United Kingdom’s National Institute for Health and Care Excellence,to alleviate the negative symptoms associated with schizophrenia.The last decade has however,seen several new larger well-controlled trials published suggesting an update is timely.AIM To asses randomised controlled trials(RCT)of art therapies for reducing the symptoms of schizophrenia–particularly negative symptoms.METHODS Searches of PubMed and Scopus were conducted until May 2019 for RCTs examining the impact of art therapies on psychosis(positive,negative and total)symptoms in people diagnosed with schizophrenia.Study quality was assessed using the Cochrane risk of bias tool.Random effects meta-analyses were used to derive overall effect sizes.Moderator analyses were conducted using both metaregression and categorical comparisons.RESULTS We identified 133 articles,of which 9 RCTs involving 948 participants(475 assigned to art therapies and 473 controls)met our inclusion criteria.Using random effects models,we calculated pooled effect sizes(Hedges g)for end-oftrial symptomatic outcomes.Effect sizes both for total symptoms[g=-0.27,95%confidence interval(CI)-0.60 to 0.05,k=6]and for positive symptoms(g=-0.10,95%CI-0.35 to 0.15,k=6)were non-significant;however,we did find significant reduction of negative symptoms(g=-0.42,95%CI-0.70 to-0.14,k=9).Metaregression revealed that negative symptom reduction was larger in trials with a greater proportion of women and in trials with younger patients.Crucially,the negative symptom reduction following art therapies was limited to lower quality trials and did not emerge in trials that used blind assessment of outcomes.CONCLUSION This review presents a comprehensive meta-analysis of art therapies in schizophrenia in terms of both studies included and participant numbers.We found that art therapies did not significantly reduce total or positive symptoms.A'small'therapeutic effect was found for negative symptoms,but we show that the effect is not present in blind trials and may be subject to publication bias. | Keith R Laws William Conway | 2019 | World Journal of Psychiatry2019,9,8: | 3 |
| 12 | Helicobacter pylori eradication in Western Australia using novel quadruple therapy combinations显示文摘 | C. Y. Tay H. M. Windsor F. Thirriot W. Lu C. Conway T. T. Perkins B. J. Marshall | 2012 | Aliment Pharmacol Ther (pt)2012,,11: | 3 |
| 13 | Endoscopic mucosal resection and endoscopic submucosal dissection显示文摘 | Sergey V. Kantsevoy Douglas G. Adler Jason D. Conway David L. Diehl Francis A. Farraye Richard Kwon Petar Mamula Sarah Rodriguez Raj J. Shah Louis Michel Wong Kee Song William M. Tierney | 2008 | Gastrointestinal Endoscopy2008,,1: | 2 |
| 14 | The Genetic Architecture of Multiple Myeloma显示文摘 | Steven M. Prideaux Emma Conway O’Brien Timothy J. Chevassut G?sta Gahrton | 2014 | Advances in Hematology2014,,: | 2 |
| 15 | Diagnostic analyses for mechanisms of self-discharge of electrochemical capacitors and batteries显示文摘 | Brian E. Conway W.G. Pell T-C. Liu | 1997 | Journal of Power Sources1997,,1: | 2 |
| 16 | CT virtual simulation显示文摘 | Conway J Robinson M H | 1997 | Br J Radiol1997,70,: | 2 |
| 17 | 高速光传输中PMD障碍的分析及解决显示文摘1引言 在流媒体和其他多媒体应用的推动下,用户对带宽的需求越来越高,促使电信运营商不断提高网络容量。对于10Gbit/s、40Gbit/s或更高的传输速率,现有的网络设备已可以支持,但是现有的光网络不一定能够支持,高速传输时的色散(CD)和偏振模色散(PMD)等都会导致网络异常。在CD方面业界已开发出经济、有效的解决方案,并已在网络中部署,但是在PMD方面仍然没有完善的解决方案。 | Francis Audet Robert Conway | 2009 | 电信科学2009,25,3: | 2 |
| 18 | Microstructure-based multiphysics modeling for semiconductor integration and packaging显示文摘Semiconductor technology and packaging is advancing rapidly toward system integration where the packaging is co-designed and co-manufactured along with the wafer fabrication.However,materials issues,in particular the mesoscale microstructure,have to date been excluded from the integrated product design cycle of electronic packaging due to the myriad of materials used and the complex nature of the material phenomena that require a multiphysics approach to describe.In the context of the materials genome initiative,we present an overview of a series of studies that aim to establish the linkages between the material microstructure and its responses by considering the multiple perspectives of the various multiphysics fields.The microstructure was predicted using thermodynamic calculations,sharp interface kinetic models,phase field,and phase field crystal modelingtechniques.Based on the predicted mesoscale microstructure,linear elastic mechanical analyses and electromigration simulations on the ultrafine interconnects were performed.The microstructural index extracted by a method based on singular value decomposition exhibits a monotonous decrease with an increase in the interconnect size.An artificial neural network-based fitting revealed a nonlinear relationship between the microstructure index and the average von Mises stress in the ultrafine interconnects.Future work to address the randomness of microstructure and the resulting scatter in the reliability is discussed in this study. | Zhiheng Huang Hua Xiong Zhiyong Wu Paul Conway Hugh Davies Alan Dinsdale Yunfei En Qingfeng Zeng | 2014 | Chinese Science Bulletin2014,59,15: | 2 |
| 19 | Transition from ''supercapacitor'' to ''battery'' behavior in electrochemical storage 显示文摘 | CONWAY R E | 1991 | J Electrochem Soc1991,138,6: | 2 |
| 20 | 87Sr/86Sr,143Nd/144Nd and REEs in Silurian phosphatic fossils显示文摘 | Bertram C J Elderfield H Aldridge R J Conway Morris S | 1992 | Earth Planetary Science Letter1992,113,: | 2 |