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		题名	作者	年代	出处	被引量
	1	Adjuvant therapy sparing in rectal cancer achieving complete response after chemoradiation显示文摘AIM:To evaluate the long-term results of conventional chemoradiotherapy and laparoscopic mesorectal excision in rectal adenocarcinoma patients without adjuvant therapy.METHODS:Patients with biopsy-proven adenocarcinoma of the rectum staged cT3-T4 by endoscopic ultrasound or magnetic resonance imaging received neoadjuvant continuous infusion of 5-fluorouracil for five weeks and concomitant radiotherapy.Laparoscopic surgery was planned after 5-8 wk.Patients diagnosed with ypT0N0 stage cancer were not treated with adjuvant therapy according to the protocol.Patients with ypT1-2N0 or ypT3-4 or N+were offered 5-fluorouracil-based adjuvant treatment on an individual basis.An external cohort was used as a reference for the findings.RESULTS:One hundred and seventy six patients were treated with induction chemoradiotherapy and 170underwent total mesorectal excision.Cancer staging of ypT0N0 was achieved in 26/170(15.3%)patients.After a median follow-up of 58.3 mo,patients withypT0N0 had five-year disease-free and overall survival rates of 96%(95%CI:77-99)and 100%,respectively.We provide evidence about the natural history of patients with localized rectal cancer achieving a complete response after preoperative chemoradiation.The inherent good prognosis of these patients will have implications for clinical trial design and care of patients.CONCLUSION:Withholding adjuvant chemotherapy after complete response following standard neoadjuvant chemoradiotherapy and laparoscopic mesorectal excision might be safe within an experienced multidisciplinary team.	Xabier García-Albéniz Rosa Gallego Ralf Dieter Hofheinz Gloria Fernández-Esparrach Juan Ramón Ayuso-Colella Josep Antoni Bombí Carles Conill Miriam Cuatrecasas Salvadora Delgado Angels Ginés Rosa Miquel Mario Pagés Estela Pineda Verónica Pereira Aarón Sosa Oscar Reig Iván Victoria Luis Feliz Antonio María de Lacy Antoni Castells Iris Burkholder Andreas Hochhaus Joan Maurel	2014	World Journal of Gastroenterology2014，20，42：	5
	2	Poroplastic damage model for claystones显示文摘	CONIL N DJERAN-MAIGER I CABRILLAR R	2004	Applied Clay Science2004，26，1234：	1
	3	Poroplastic damage model for claystones 显示文摘	CONIL N DJERAN - MAIGRE I CABRILLAC R SU K	2004	Applied Clay Science2004，26，14：	1
	4	Strontium-89 for palliation of pain from bone metastases in patients with prostate and breast cancer显示文摘	Francesca Pons Ramón Herranz Alicia Garcia Sergi Vidal-Sicart Carles Conill Juan José Grau Joan Alcover David Fuster Jordi Setoain	1997	European Journal of Nuclear Medicine1997，，10：	1
	5	Poroplastic damage model for claystones显示文摘	CONIL N DJERAN-MAIGRE I CABRILLAC R	2004	AppliedClay Science2004，26，：	1
	6	Poroplastic damage model for claystones显示文摘	CONIL N DJERAN-Maigre I CABRILLAC R	2004	Applied Clay Science2004，26，：	1
	7	Phase I trial of neoadjuvant chemoradiotherapy (CRT) with capecitabine and weekly irinotecan followed by laparoscopic total mesorectal excision (LTME) in rectal cancer patients显示文摘	Lisardo Ugidos Salvadora Delgado Carlos Conill Angels Ginés Rosa Gallego Juan Ramón Ayuso Rosa Miquel Monica Tosca Antonio Lacy Antoni Castells Joan Maurel	2009	Investigational New Drugs2009，，3：	1

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