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| 1 | Impacts of land use and land cover changes on hydrological processes and sediment yield determined using the SWAT model显示文摘Land use and land cover(LULC)changes strongly affect local hydrology and sediment yields.The current study focused on a basin in the Brazilian Amazon and had the following three objectives:(1)to perform an effective diagnosis of flow and sediment yield,(2)to evaluate the impacts of LULC changes over the last 40 years on the hydro-sedimentological variables,and(3)to investigate the impacts of the possible trends or breaking points in the flow,surface runoff,and sediment yield series.The Soil and Water Assessment Tool(SWAT)model validation showed that the simulated results were consistent with the data measured in the dynamic reproduction of flow seasonality.Furthermore,changes in LULC altered surface runoff,sediment yield,and flow according to the Mann-Kendall and Pettitt non-parametric tests.It was also observed that the sub-basins in which pastureland is predominant are more susceptible to increased surface runoff and sediment yield.According to trend and homogeneity tests,these sub-basins had break points in the time series of these variables.On the other hand,in the sub-basins whose land cover is predominantly forest,the time series is homogeneous and trendless.The current study highlighted the impacts that 40 years of LULC changes in an Amazonian basin had on hydro-sedimentological variables,which,in turn,can play an important role in changing the hydrological cycle,consequently these changes can also impact diverse human activities in the region,such as agribusiness,livestock,energy production,food security,and public water supply.Thus,it is concluded that the SWAT model is a good estimator of hydro-sedimentological processes in Amazonian basins and can be used by decision makers in the management of water and environmental resources. | Edivaldo Afonso de Oliveira Serrao Madson Tavares Silva Thomas Rocha Ferreira Lorena Conceiçao Paiva de Ataide Cleber Assis dos Santos Aline Maria Meiguins de Lima Vicente de Paulo Rodrigues da Silva Francisco de Assis Salviano de Sousa Denis Jose Cardoso Gomes | 2022 | International Journal of Sediment Research2022，37，1： | 3 |
| 2 | Adverse effects of cadmium exposure on mouse sperm显示文摘 | Helena Oliveira Marcello Spanò Concei??o Santos Maria de Lourdes Pereira | 2009 | Reproductive Toxicology2009，，4： | 2 |
| 3 | 定期运动有助于改善高血压患者蛋白质稳态、炎症和血管活性显示文摘体育锻炼是一种公认的非药物控制血压的策略,除了降低血压外,运动还能对高血压患者的炎症特征、自主功能、内皮功能和抗氧化状态产生积极的影响。但其对高血压患者的蛋白质稳态的影响尚不清楚。已有动物研究表明,运动训练干预可以改善蛋白质质量控制机制,但在动物模型中报告的积极作用仍有待于在人类身上得到证实。本研究旨在根据报告的运动习惯,评估患高血压成年人的蛋白质稳态,生活质量以及炎症、氧化应激和血管活性生物标记物状态。 | Teixeira M Gouveia M Duarte A Ferreira M Simões MI Conceição M Silva G Magalhães S Ferreira R Nunes A Vieira SI Ribeiro F 周卫(译) 叶鹏(审校) | 2020 | 中华高血压杂志2020，28，12： | 2 |
| 4 | Doehlert matrix for optimisation of procedure for determination of nickel in saline oil-refinery effluents by use of flame atomic absorption spectrometry after preconcentration by cloud-point extraction显示文摘 | Marcos Bezerra André L. B. Concei??o Sérgio L. C. Ferreira | 2004 | Analytical and Bioanalytical Chemistry2004，，3： | 1 |
| 5 | Regulation of chlorophyll biosynthesis and degradation by salt stress in sunflower leaves显示文摘 | Concei??o Vieira Santos | 2004 | Scientia Horticulturae2004，，1： | 1 |
| 6 | Effect of pomegranate (Punica granatum) juice intake on hepatic oxidative stress显示文摘 | Ana Faria Rosário Monteiro Nuno Mateus Isabel Azevedo Concei??o Calhau | 2007 | European Journal of Nutrition2007，，5： | 1 |
| 7 | A new environmental Kuznets curves?Relationship between direct material input and income per capita:evidence from industrialised countries显示文摘 | CANAS?ngela Ferr?o Paulo Concei??o Pedro | 2003 | Ecological Economics2003，46，2： | 1 |
| 8 | Specific schistosomiasis treatment as a strategy for disease control显示文摘 | Coura JR Concei o MJ | 2010 | Mem Inst Oswaldo Cruz2010，105，4： | 1 |
| 9 | Keggin-type polyoxotungstates as catalysts in the oxidationof cyclohexane by dilute aqueous hydrogen peroxide显示文摘 | Sim5es M M Q Concei^a C M M Gamelas J A F | 1999 | JMol Coia//41999，144，46： | 1 |
| 10 | The rmoanalytical characterization of castor oil biodiesel 显示文摘 | MARTA M CONCEI FERNANDO C SILVA | 2007 | Renewable and Sustainable Energy Reviews2007，11，5： | 1 |
| 11 | Sympathetic activity in breast cancer and metastasis:partners in crime显示文摘The vast majority of patients with advanced breast cancer present skeletal complications that severely compromise their quality of life.Breast cancer cells are characterized by a strong tropism to the bone niche.After engraftment and colonization of bone,breast cancer cells interact with native bone cells to hinder the normal bone remodeling process and establish an osteolytic“metastatic vicious cycle”.The sympathetic nervous system has emerged in recent years as an important modulator of breast cancer progression and metastasis,potentiating and accelerating the onset of the vicious cycle and leading to extensive bone degradation.Furthermore,sympathetic neurotransmitters and their cognate receptors have been shown to promote several hallmarks of breast cancer,such as proliferation,angiogenesis,immune escape,and invasion of the extracellular matrix.In this review,we assembled the current knowledge concerning the complex interactions that take place in the tumor microenvironment,with a special emphasis on sympathetic modulation of breast cancer cells and stromal cells.Notably,the differential action of epinephrine and norepinephrine,through eitherα-orβ-adrenergic receptors,on breast cancer progression prompts careful consideration when designing new therapeutic options.In addition,the contribution of sympathetic innervation to the formation of bone metastatic foci is highlighted.In particular,we address the remarkable ability of adrenergic signaling to condition the native bone remodeling process and modulate the bone vasculature,driving breast cancer cell engraftment in the bone niche.Finally,clinical perspectives and developments on the use ofβ-adrenergic receptor inhibitors for breast cancer management and treatment are discussed. | Francisco Conceição Daniela M.Sousa Joana Paredes Meriem Lamghari | 2021 | Bone Research2021，9，1： | 1 |
| 12 | 2-aminoethyl Dihydrogen Phosphate as a Modulator of Proliferative and Apoptotic Effects in Breast Cancer Cell Lines显示文摘Background: Breast cancer is a type of cancer that affects more women throughout the world, in developing anddeveloped countries. 2-AEH2P is a phospholipid analog of cellular membrane, which makes it different from existing molecules fortheir absorption, stability and display anti-inflammatory, anti-proliferative and pro-apoptotic properties. Methods: MCF-7 humanbreast adenocarcinoma cells were treated with 2-AEH2P. The viability and adhesion cells were evaluated by MTT assay. Cell cyclephases, apoptosis, markers and mitochondrial potential were assessed by flow cytometry. Morphological ultrastructural analyzeswere performed by laser confocal microscopy. Results: MCF-7 Tumor cells acquired round shapes, lost cytoplasmic expansions,formed clusters in suspension and decreased significantly viability. There were changes in the morphology, membrane fragmentationand loss of cytoplasmic projection. The obtained concentrations for IC50% were 37.2;25.8;1.8 mM for periods of 24, 48 and 72 h,respectively. Changes in the distribution of cell population phases of the cell cycle showed an increase in fragmented DNA and anincrease in the G2/M phase. The expression β-gal showed proliferative reduction induced by 2-AEH2P. Laser confocal microscopyshowed changes in the mitochondrial membrane and alteration in distribution. Proliferative index of MCF-7 tumor cells treated with2-AEH2P decreased significantly when compared to fibroblast normal cells. The compound 2-AEH2P is a phospholipid withantiproliferative potential and apoptosis modulator. | Manuela Garcia Laveli da Silva Laertty Garcia de Sousa Cabral Monique Gonçalves Alves Thais deOliveira Conceição Henrique Hesse Rosa Andrea Nogueira Laiso Daniel da Conceição Rabelo Durvanei Augusto Maria | 2021 | Journal of Pharmacy and Pharmacology2021，9，3： | 1 |
| 13 | Therapeutic failure of praziquantel in the treatment of Schistosoma haematobium infec- tion in Brazilians returning from Africa显示文摘 | Silva IM Thiengo R Concei o MJ | 2005 | Memorias do Instituto Oswaldo Cruz2005，100，4： | 1 |
| 14 | Physiological responses of Senegalese sole(Solea senegalensis Kaup,1858)after stress challenge:Effects on non-specific immune parameters,plasma free amino acids and energy metabolism显示文摘 | Costas B Conceiao L E C Aragao C | 2011 | Aquaculture2011，316，1： | 1 |
| 15 | Soil vapor extraction in sandy soils:Influence of airflow rate显示文摘 | JoséTomás Albergaria Maria Da Conceio M Delerue-Matos Cristina | 2008 | Chemosphere2008，73，9： | 1 |
| 16 | Physiological responses of Senegalese sole(Solea senegalensis Kaup,1858) after stress challenge:Effects on non-specific immune parameters,plasma free amino acids and energy metabolism显示文摘 | Costas B Concei??o L E C Arag?o C | 2011 | Aquaculture2011，316，1： | 1 |
| 17 | The commercialization decisions of research - based spin - off: targeting the market for technology 显示文摘 | CONCEI CAO O | 2012 | Techn- ovation2012，，32： | 1 |
| 18 | High-level expression of IMP-5 carbapenemase owing to point mutation in the -35 promoter region of class 1 integron among Pseudomonas aeruginosa clinical isolates显示文摘 | Brízio A Concei Pimentel M | | 0，，01： | 1 |
| 19 | Thermoanalytical,kinetic and rheological parameters of commercial edible vegetable oils显示文摘 | SANTOS J C O SANTOS I M G CONCEI C'A-O M M | 2004 | Journal of thermal analysis and calorimetry2004，75，2： | 1 |
| 20 | Corporate Legal Responsibility: A Levinasian Perspective显示文摘 | Concei??o Soares | 2008 | Journal of Business Ethics2008，，3： | 1 |
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