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| 1 | FAIR Principles:Interpretations and Implementation Considerations显示文摘The FAIR principles have been widely cited,endorsed and adopted by a broad range of stakeholders since their publication in 2016.By intention,the 15 FAIR guiding principles do not dictate specific technological implementations,but provide guidance for improving Findability,Accessibility,Interoperability and Reusability of digital resources.This has likely contributed to the broad adoption of the FAIR principles,because individual stakeholder communities can implement their own FAIR solutions.However,it has also resulted in inconsistent interpretations that carry the risk of leading to incompatible implementations.Thus,while the FAIR principles are formulated on a high level and may be interpreted and implemented in different ways,for true interoperability we need to support convergence in implementation choices that are widely accessible and(re)-usable.We introduce the concept of FAIR implementation considerations to assist accelerated global participation and convergence towards accessible,robust,widespread and consistent FAIR implementations.Any self-identified stakeholder community may either choose to reuse solutions from existing implementations,or when they spot a gap,accept the challenge to create the needed solution,which,ideally,can be used again by other communities in the future.Here,we provide interpretations and implementation considerations(choices and challenges)for each FAIR principle. | Annika Jacobsen Ricardo de Miranda Azevedo Nick Juty Dominique Batista Simon Coles Ronald Cornet Melanie Courtot Merce Crosas Michel Dumontier Chris T.Evelo Carole Goble Giancarlo Guizzardi Karsten Kryger Hansen Ali Hasnain Kristina Hettne Jaap Heringa Rob W.W.Hooft Melanie Imming Keith G.Jeffery Rajaram Kaliyaperumal Martijn GKersloot Christine R.Kirkpatrick Tobias Kuhn Ignasi Labastida Barbara Magagna PeterMcQuilton Natalie Meyers Annalisa Montesanti Mirjam van Reisen Philippe Rocca-Serra Robert Pergl Susanna-Assunta Sansone Luiz Olavo Bonino da Silva Santos Juliane Schneider George Strawn Mark Thompson Andra Waagmeester Tobias Weigel Mark D.Wilkinson Egon L.Willighagen Peter Wittenburg Marco Roos Barend Mons Erik Schultes | 2020 | Data Intelligence2020，2，1： | 26 |
| 2 | The prevalence of human papilIomavirus in cervical cancer:a systematic review显示文摘 | Rgosa MI Silva OD cle Azedo $im es PW | 2015 | lnt J Gynecol Cancer2015，25，5： | 1 |
| 3 | DNA damage and repair in haemolymph cells of golden mussel exposed to environmental contaminants显示文摘 | Villela IV Oliveria IM Silva J | 2006 | Mutation Research2006，605，： | 1 |
| 4 | NR3C1 polymor- phisms in Brazilians of Caucasian, African, and Asian ancestry: glucocorticoid sensitivity and genotype association显示文摘 | Souza MC Martins CS Silva -Junior IM | 2014 | Arq Bras En- docrinol Metabol2014，58，： | 1 |
| 5 | Mixed testicular germ cell tumour in a patient with previous pineal germinoma显示文摘 | Silva VB Azevedo AL Costa IM | 2011 | J Neurooncol2011，101，1： | 1 |
| 6 | Therapeutic failure of praziquantel in the treatment of Schistosoma haematobium infec- tion in Brazilians returning from Africa显示文摘 | Silva IM Thiengo R Concei o MJ | 2005 | Memorias do Instituto Oswaldo Cruz2005，100，4： | 1 |
| 7 | Catalyticstudy in wet oxidation of effluents from formaldehyde industry显示文摘 | Silva AMT Castelo-Branco IM Quinta-ferreira RM | 2003 | Chemical Engineering Science2003，58，36： | 1 |
| 8 | Evaluation of inoculum of Candida guilliermondii grown in presence of glucose on xylose reductase and xylitoldehydrogenase activities and xylitol production during batch fermentation of sugarcane bagasse hydrolysate显示文摘 | Silva DDV Felipe MGA Mancilha IM | 2005 | Appl Biochem Biotechnol2005，121，： | 1 |
| 9 | Development of the BG-Malaria trap as an alternative to human-landing catches for the capture of Anopheles darlingi 显示文摘 | Gama RA Silva IM Geier M | 2013 | Mere Inst Oswaldo Cruz2013，108，6： | 1 |
| 10 | Schistosomiasis haemato- bia: histopathologieal course determined by eystoscopy in a pa- tient in whom praziquantel treatment failed 显示文摘 | Silva IM Pereira FE Thiengo R | 2008 | Rev Inst Med Trop Sao Paulo2008，50，6： | 1 |
| 11 | Therapeutic failure of praziquantel in the treatment of Schistosoma haematobium infection in Brazilians returning from Africa 显示文摘 | Silva IM Thiengo R Conceicao MJ | 2005 | Mere Inst Oswaldo Cruz2005，100，4： | 1 |
| 12 | I)etermi- nation of 3-a-hydroxytibolone in human plasma by LC-MS/MS: applica- tion for a pharmacokinetic study after administration of a tibolone formu- lation 显示文摘 | de Santana e Silva Cardoso FF C6sar IC Mundim IM | 2013 | Biomed Chromatogr2013，27，11： | 1 |
| 13 | Aging of signal transduction pathways, and pathology显示文摘 | Carlson ME Silva HS Conboy IM | 2008 | Exp Cell Res2008，314，9： | 1 |
| 14 | Inhibition of PI3K/Akt pathway impairs G2/M transition of cell cycle in late developing progenitors of the avian embryo retina显示文摘 | Ornelas IM Silva TM Fragel-Madeira L | 2013 | Plo S one2013，8，53： | 1 |
| 15 | Blood pressure level, trend, and variabityin Dunedin children: an 8 year study of single birth cohort 显示文摘 | George IM Williams SM Silva PA | 1990 | Circulation1990，82，： | 1 |
| 16 | Therapeutic failure of praziquantel in the treatment of Schistosoma haematobium infection in Brazilians returning from Africa 显示文摘 | Silva IM Thiengo R Conceicao MJ | 2005 | Mem Inst Oswaldo Cruz2005，100，4： | 1 |
| 17 | The epidemiolo- gy of carcinoid tumors in England and Scotland 显示文摘 | Newton JN Swerdlow A J dos Santos Silva IM | 1994 | Br J Cancer1994，70，： | 1 |
| 18 | Production of β-carotene by a Rhodotorula strain grown on sugarcane juice显示文摘 | Matelli HL Silva IM Souza NO | 1990 | Biotechnol Lett1990，12，3： | 1 |
| 19 | Therapeutic failure of praziquantel in the treatment of Schistosoma haematobium infection in Brazilians returning from Africa 显示文摘 | Silva IM Thiengo R Coneeiqao M J | 2005 | Mem Inst Oswaldo Cruz2005，100，4： | 1 |
| 20 | The epidemiology of carcinoid tumours in England and Scotland显示文摘 | Newton JN Swerdlow AJ dos Santos Silva IM | 1994 | Br J Cancer1994，70，5： | 1 |
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